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The map label for this gene is aroB

Identifier: 18978063

GI number: 18978063

Start: 1571339

End: 1572346

Strand: Direct

Name: aroB

Synonym: PF1691

Alternate gene names: 18978063

Gene position: 1571339-1572346 (Clockwise)

Preceding gene: 18978062

Following gene: 18978064

Centisome position: 82.34

GC content: 37.9

Gene sequence:

>1008_bases
ATGGAAGGGATAATTTTTGGAGATCTTTCAACACTTCCCGATTTGCTTTCTTCTCTTTCTCCCTACAAGGTAGTAGTTCT
AACTAACACAACTCTAAAGGAATTATGGCTCGAAGAAGTTCTAACGTGGTTAAAAGAGTTCAAACCCCAGACAATCGTTG
TTCCAGATGGGGAAAAATACAAAGATTTAGATACAGTTAGATATATTTGGGAAAAATTACTAGAAATGGGATTTACACGA
AGATCACTCCTAATAGGGTTAGGTGGAGGGGTTATAACAGACATTGCTGGTTTTGTTGCCTCAACATATATGAGAGGAAC
ATACCTAGGTCTCGTTCCCACAACACTTCTAGCCCAAGTTGATGCAGCTATTGGGGGAAAAACTGGCATAAATTTCTACG
GGAAGAATATAATTGGAACATTTTACCTTCCGAAATTCGTGCTAATTTGTAGGGACTTTCTCAAGACCCTCCCAATGGTG
GAAATTCTTAATGGGTTAGCTGAAGTTGTGAAGTATGGAATACTAGACAAAGAAGTCTACAATGCAATTAAAACAATGAA
CTCTCCCAGGGAAATTGTAGAAAGGGAGGATATAATAAAGAAATCTGTAGCGGTAAAACTGAGAATCGTAGAGGAAGATT
TAAAGGAAAACGGAAAGAGGAGAGTTCTAAACTTGGGTCACACAGTAGGACATGCCATAGAGAAAATTTCTGACTACAAA
ATAAAACACGGCTTCGCAGTTTCAATGGGATTAGTTGTGGAAGCAAAAATTGGAGAAATATTGTATGGCTTTGATTCAGG
GAAAGTTGTTGAGATACTAACTAAATTTGGTTTGCCTGTAAAAATACCCTTTGATCCATACACAACTCTTCAAGCCATGA
AAATCGACAAAAAGGCTTGGTACGGAAAGATAGTTATTGTTGTTCCGGTTGAGATTGGAAAAGCCAATATTGAGGAGGTA
GATGAAAAGATAATTCTACAAGCGCTGGAGGAAGCTAAAAATGCCTAA

Upstream 100 bases:

>100_bases
TTGAAGTTCATCCAGAACCAGAAAAGGCACTCTCAGATTCCCAGCAACAACTAACGTTTGATGACTTCTTACAACTACTA
AAAGAGCTGGAGGCCCTGGG

Downstream 100 bases:

>100_bases
ATTGGCCGGAGTTATAATAGCTAAAACCATTGAAGAAGCTGTAAAAAAGATAAAGCTACATGAAGCCGACCTTTATGAGC
TTAGAGTAGATTACCTGGAG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MEGIIFGDLSTLPDLLSSLSPYKVVVLTNTTLKELWLEEVLTWLKEFKPQTIVVPDGEKYKDLDTVRYIWEKLLEMGFTR
RSLLIGLGGGVITDIAGFVASTYMRGTYLGLVPTTLLAQVDAAIGGKTGINFYGKNIIGTFYLPKFVLICRDFLKTLPMV
EILNGLAEVVKYGILDKEVYNAIKTMNSPREIVEREDIIKKSVAVKLRIVEEDLKENGKRRVLNLGHTVGHAIEKISDYK
IKHGFAVSMGLVVEAKIGEILYGFDSGKVVEILTKFGLPVKIPFDPYTTLQAMKIDKKAWYGKIVIVVPVEIGKANIEEV
DEKIILQALEEAKNA

Sequences:

>Translated_335_residues
MEGIIFGDLSTLPDLLSSLSPYKVVVLTNTTLKELWLEEVLTWLKEFKPQTIVVPDGEKYKDLDTVRYIWEKLLEMGFTR
RSLLIGLGGGVITDIAGFVASTYMRGTYLGLVPTTLLAQVDAAIGGKTGINFYGKNIIGTFYLPKFVLICRDFLKTLPMV
EILNGLAEVVKYGILDKEVYNAIKTMNSPREIVEREDIIKKSVAVKLRIVEEDLKENGKRRVLNLGHTVGHAIEKISDYK
IKHGFAVSMGLVVEAKIGEILYGFDSGKVVEILTKFGLPVKIPFDPYTTLQAMKIDKKAWYGKIVIVVPVEIGKANIEEV
DEKIILQALEEAKNA
>Mature_335_residues
MEGIIFGDLSTLPDLLSSLSPYKVVVLTNTTLKELWLEEVLTWLKEFKPQTIVVPDGEKYKDLDTVRYIWEKLLEMGFTR
RSLLIGLGGGVITDIAGFVASTYMRGTYLGLVPTTLLAQVDAAIGGKTGINFYGKNIIGTFYLPKFVLICRDFLKTLPMV
EILNGLAEVVKYGILDKEVYNAIKTMNSPREIVEREDIIKKSVAVKLRIVEEDLKENGKRRVLNLGHTVGHAIEKISDYK
IKHGFAVSMGLVVEAKIGEILYGFDSGKVVEILTKFGLPVKIPFDPYTTLQAMKIDKKAWYGKIVIVVPVEIGKANIEEV
DEKIILQALEEAKNA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=331, Percent_Identity=38.0664652567976, Blast_Score=196, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6320332, Length=346, Percent_Identity=34.393063583815, Blast_Score=159, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_PYRFU (Q8U0A8)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_579420.1
- ProteinModelPortal:   Q8U0A8
- SMR:   Q8U0A8
- EnsemblBacteria:   EBPYRT00000005582
- GeneID:   1469568
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1691
- NMPDR:   fig|186497.1.peg.1739
- GeneTree:   EBGT00050000022389
- HOGENOM:   HBG632303
- OMA:   TERMISD
- ProtClustDB:   PRK00002
- BRENDA:   4.2.3.4
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 37385; Mature: 37385

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGIIFGDLSTLPDLLSSLSPYKVVVLTNTTLKELWLEEVLTWLKEFKPQTIVVPDGEKY
CCCEEECCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
KDLDTVRYIWEKLLEMGFTRRSLLIGLGGGVITDIAGFVASTYMRGTYLGLVPTTLLAQV
CHHHHHHHHHHHHHHCCCCHHHHEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
DAAIGGKTGINFYGKNIIGTFYLPKFVLICRDFLKTLPMVEILNGLAEVVKYGILDKEVY
HHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHH
NAIKTMNSPREIVEREDIIKKSVAVKLRIVEEDLKENGKRRVLNLGHTVGHAIEKISDYK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCH
IKHGFAVSMGLVVEAKIGEILYGFDSGKVVEILTKFGLPVKIPFDPYTTLQAMKIDKKAW
HCCCEEEEECEEEEEECCCEEEECCCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHH
YGKIVIVVPVEIGKANIEEVDEKIILQALEEAKNA
HCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEGIIFGDLSTLPDLLSSLSPYKVVVLTNTTLKELWLEEVLTWLKEFKPQTIVVPDGEKY
CCCEEECCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
KDLDTVRYIWEKLLEMGFTRRSLLIGLGGGVITDIAGFVASTYMRGTYLGLVPTTLLAQV
CHHHHHHHHHHHHHHCCCCHHHHEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
DAAIGGKTGINFYGKNIIGTFYLPKFVLICRDFLKTLPMVEILNGLAEVVKYGILDKEVY
HHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHH
NAIKTMNSPREIVEREDIIKKSVAVKLRIVEEDLKENGKRRVLNLGHTVGHAIEKISDYK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCH
IKHGFAVSMGLVVEAKIGEILYGFDSGKVVEILTKFGLPVKIPFDPYTTLQAMKIDKKAW
HCCCEEEEECEEEEEECCCEEEECCCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHH
YGKIVIVVPVEIGKANIEEVDEKIILQALEEAKNA
HCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA