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The map label for this gene is hypE [C]

Identifier: 18977958

GI number: 18977958

Start: 1481131

End: 1482198

Strand: Reverse

Name: hypE [C]

Synonym: PF1586

Alternate gene names: 18977958

Gene position: 1482198-1481131 (Counterclockwise)

Preceding gene: 18977960

Following gene: 18977954

Centisome position: 77.67

GC content: 39.79

Gene sequence:

>1068_bases
ATGCTAAGCATTCATACTGCACCTTCATTATTATCACCGAAAACATTTTTTTGTTGGGGAATCCTTCCTATTTGGGGGAG
CAAAATGTTTGCAGGTAAAGTTCCACCAGAGGTACTTAAAGAAATCGTTTTTAAAAACTTGAACGTGGAAAAGGCTCATA
GGCTAATAATTGGCCCAGGAGTTGGAATAGATGCTGCTGCTTTAGATTTTGGGGATTACGTAGTAGTTGCTTCAACTGAT
CCAATCACAGGTGCTGAGGAGAGAATTGGATTTTATGCTGTTCATGTAAATGCCAATGACGTGGCAACATTTGGAGCTAA
ACCTAAGTGGTTTCTTGTTAACATATTACTTCCAGAGGGAAGTGATGAGTCTACTTTAAGGGAAATCATGGATGAAATAA
GAGAAGTAGCCTCTTCGCTGGACGTTTCAATAATTGGGGGACATACTGAGGTTACTCCAGGATTGAAGAAGCCAATAGTT
GTTGGAACTATGCTGGGAGAAGTGGAAAAAGATAAGCTGGTAATTCCAAATCCCAGGCCAGGAGATGCTATAATATTAAC
TAAAGGAGTTGGAATTGAGGGGACTTCTATAATTGCTCATGAGAGGGAAAAAGAGCTGAGAAGTATATTTGGAAAAGAGT
TTGTTGAGAGGGCCAAATCATACATCAATGAAATAAGTGTGGTTAAGGAAGCTTTAATAGCTAGAGAATTTGCAACTGCA
ATGCACGATCCTACAGAGGGAGGAGTTGCAAATGGGCTTCATGAGATGGCAGACATAAATGATTTGGGGTTTAGAGTTTT
CAAGAATAAGTTGATAATTAGAGAAGAGACAAAGAGGATTTGCACATTTTATGACATTGACCCGCTGTCTCTGATAAGTT
CTGGGGCTTTACTTATCTCTGTTCCCAGGGACAGCGCTCAGTTGGTTGTTCAAAAATTGCAAAGTAATGGAATAAAAGCA
AGTATAATAGGAGAATTTTTAGCTGAGAAGAAGAGGGTCATAATAGAAAATGGTGTTGAGAGACCTCTTAGGCGTCCTGA
GACTGACGAGCTTTGGAAGGTTGTGTAG

Upstream 100 bases:

>100_bases
TCATTAGCAATTAGCTTTGATGCGAGTATCATCCCTTGCTTTCTAAAATTTAAGTCTTCTGTTGCCATCTCGGCTATTCT
TTGGCATTGATTTGCTATAC

Downstream 100 bases:

>100_bases
TTTCTCTTTCTTCGATTTCTTTCCAAGCTTCTAGCAATGCTGAGAACAATCCTATTGATATGGGGCCCAGAAGAATGCCT
ACAGCACCAAAGGCCATTAT

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MLSIHTAPSLLSPKTFFCWGILPIWGSKMFAGKVPPEVLKEIVFKNLNVEKAHRLIIGPGVGIDAAALDFGDYVVVASTD
PITGAEERIGFYAVHVNANDVATFGAKPKWFLVNILLPEGSDESTLREIMDEIREVASSLDVSIIGGHTEVTPGLKKPIV
VGTMLGEVEKDKLVIPNPRPGDAIILTKGVGIEGTSIIAHEREKELRSIFGKEFVERAKSYINEISVVKEALIAREFATA
MHDPTEGGVANGLHEMADINDLGFRVFKNKLIIREETKRICTFYDIDPLSLISSGALLISVPRDSAQLVVQKLQSNGIKA
SIIGEFLAEKKRVIIENGVERPLRRPETDELWKVV

Sequences:

>Translated_355_residues
MLSIHTAPSLLSPKTFFCWGILPIWGSKMFAGKVPPEVLKEIVFKNLNVEKAHRLIIGPGVGIDAAALDFGDYVVVASTD
PITGAEERIGFYAVHVNANDVATFGAKPKWFLVNILLPEGSDESTLREIMDEIREVASSLDVSIIGGHTEVTPGLKKPIV
VGTMLGEVEKDKLVIPNPRPGDAIILTKGVGIEGTSIIAHEREKELRSIFGKEFVERAKSYINEISVVKEALIAREFATA
MHDPTEGGVANGLHEMADINDLGFRVFKNKLIIREETKRICTFYDIDPLSLISSGALLISVPRDSAQLVVQKLQSNGIKA
SIIGEFLAEKKRVIIENGVERPLRRPETDELWKVV
>Mature_355_residues
MLSIHTAPSLLSPKTFFCWGILPIWGSKMFAGKVPPEVLKEIVFKNLNVEKAHRLIIGPGVGIDAAALDFGDYVVVASTD
PITGAEERIGFYAVHVNANDVATFGAKPKWFLVNILLPEGSDESTLREIMDEIREVASSLDVSIIGGHTEVTPGLKKPIV
VGTMLGEVEKDKLVIPNPRPGDAIILTKGVGIEGTSIIAHEREKELRSIFGKEFVERAKSYINEISVVKEALIAREFATA
MHDPTEGGVANGLHEMADINDLGFRVFKNKLIIREETKRICTFYDIDPLSLISSGALLISVPRDSAQLVVQKLQSNGIKA
SIIGEFLAEKKRVIIENGVERPLRRPETDELWKVV

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=300, Percent_Identity=25.6666666666667, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 38940; Mature: 38940

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIHTAPSLLSPKTFFCWGILPIWGSKMFAGKVPPEVLKEIVFKNLNVEKAHRLIIGPG
CCEECCCCCCCCCCCEEEEEHHHHHCCCEECCCCCHHHHHHHHHHCCCHHHHCEEEEECC
VGIDAAALDFGDYVVVASTDPITGAEERIGFYAVHVNANDVATFGAKPKWFLVNILLPEG
CCCCHHEECCCCEEEEECCCCCCCCCCCCEEEEEEECCCCEEECCCCCCEEEEEEEECCC
SDESTLREIMDEIREVASSLDVSIIGGHTEVTPGLKKPIVVGTMLGEVEKDKLVIPNPRP
CCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEEEHHHCCCCCCCEECCCCCC
GDAIILTKGVGIEGTSIIAHEREKELRSIFGKEFVERAKSYINEISVVKEALIAREFATA
CCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MHDPTEGGVANGLHEMADINDLGFRVFKNKLIIREETKRICTFYDIDPLSLISSGALLIS
HCCCCCCCHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCEEEEECCCHHHHHCCCCEEEE
VPRDSAQLVVQKLQSNGIKASIIGEFLAEKKRVIIENGVERPLRRPETDELWKVV
ECCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCHHHCCCCCHHHHHHCC
>Mature Secondary Structure
MLSIHTAPSLLSPKTFFCWGILPIWGSKMFAGKVPPEVLKEIVFKNLNVEKAHRLIIGPG
CCEECCCCCCCCCCCEEEEEHHHHHCCCEECCCCCHHHHHHHHHHCCCHHHHCEEEEECC
VGIDAAALDFGDYVVVASTDPITGAEERIGFYAVHVNANDVATFGAKPKWFLVNILLPEG
CCCCHHEECCCCEEEEECCCCCCCCCCCCEEEEEEECCCCEEECCCCCCEEEEEEEECCC
SDESTLREIMDEIREVASSLDVSIIGGHTEVTPGLKKPIVVGTMLGEVEKDKLVIPNPRP
CCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEEEHHHCCCCCCCEECCCCCC
GDAIILTKGVGIEGTSIIAHEREKELRSIFGKEFVERAKSYINEISVVKEALIAREFATA
CCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MHDPTEGGVANGLHEMADINDLGFRVFKNKLIIREETKRICTFYDIDPLSLISSGALLIS
HCCCCCCCHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCEEEEECCCHHHHHCCCCEEEE
VPRDSAQLVVQKLQSNGIKASIIGEFLAEKKRVIIENGVERPLRRPETDELWKVV
ECCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCHHHCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]