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The map label for this gene is pdxS [H]

Identifier: 18977901

GI number: 18977901

Start: 1425928

End: 1426935

Strand: Reverse

Name: pdxS [H]

Synonym: PF1529

Alternate gene names: 18977901

Gene position: 1426935-1425928 (Counterclockwise)

Preceding gene: 18977902

Following gene: 18977900

Centisome position: 74.78

GC content: 44.94

Gene sequence:

>1008_bases
ATGGATAAGATGAAAATAATTATGGAGAAGGGAACTGAAAGGCTCAAGAGAGGATTTGCAAAGATGGTAAAGGGCGGAGT
CATTATGGACGTTACGAATGCTGAACAGGCTAGAATTGCAGAGGAAGCTGGTGCTGTAGCAGTAATGGCTCTTCACAAGG
TCCCCGCTGATATTAGAAAGGCTGGTGGAGTTGCTAGAATGGCGCCAGTGGAGAAGATTCAGGAGATAATGGATGCCGTT
ACAATTCCAGTAATGGCAAAGGTTAGAATTGGCCATGAAGCTGAGGCAAGAATTCTTGAGGCCTTAGGGGTTGATATGAT
CGATGAAAGTGAAGTTCTAACTCCAGCAGATCCATTCTTCCACATATATAAGAAGAAGTTCACAGTTCCATTCGTTTGTG
GTGCAAGGAACTTAGGAGAGGCCGTGAGGAGGATATGGGAAGGAGCCGCAATGATTAGAACAAAGGGAGAAGCAGGAACT
GGAAACATTATTGAGGCCGTGAGGCATGTGAGGCTAGTTAATGAAAACATAAGATTAATTCAGAGAATGACTGATGAGGA
AATATATGGTGTTGCAGAGAAGTTTGCAGAACCATACTTAAGGTTGGCATTCAGCGTTAAGGAAATAAGCGGTTTACCAA
AGAGAGTCCTCGAAAATGAGCCCATCTATGAGGGCTTTACATACAGGGAAATCGTTGATGGTCTCTACAAGATTCTCTTA
GAGATAAAGAAGCTTGGAAGGTTGCCAGTAGTGAACTTTGCTGCAGGTGGAGTTGCCACACCAGCTGATGCAGCTCTAAT
GATGGCAATGGGTATGGACGGTGTGTTCGTAGGTTCTGGAATCTTCAAGAGCTCAAACCCACCAGCAATGGCAAGGGCAA
TAGTTGAGGCAGTGAACCACTGGGATGAGCCTGATGTTCTTGCCGAGATAAGCAGGGAAATTGGTGAACCAATGCGTGGG
CAAGATATAGCGGAGTTAGAAGTTAGAATGGAAGAGAGGGGAGTTTGA

Upstream 100 bases:

>100_bases
TTTTATTCTTTTTTGCCAATGGTTTGCTAAATTTTAGGTAAGGTTTATATAAAGTTTTAACTTGATATTTTGTTGAAAGA
CTATACTTGAGGTGGTTAGC

Downstream 100 bases:

>100_bases
ATTTCTCTTCTCTATTTTTTGAGGTGATTTAATGGTCAAGATAGGTGTTATTGGCCTTCAGGGAGATGTAAGCGAGCACA
TTGAAGCTACTAAAAGGGCC

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MDKMKIIMEKGTERLKRGFAKMVKGGVIMDVTNAEQARIAEEAGAVAVMALHKVPADIRKAGGVARMAPVEKIQEIMDAV
TIPVMAKVRIGHEAEARILEALGVDMIDESEVLTPADPFFHIYKKKFTVPFVCGARNLGEAVRRIWEGAAMIRTKGEAGT
GNIIEAVRHVRLVNENIRLIQRMTDEEIYGVAEKFAEPYLRLAFSVKEISGLPKRVLENEPIYEGFTYREIVDGLYKILL
EIKKLGRLPVVNFAAGGVATPADAALMMAMGMDGVFVGSGIFKSSNPPAMARAIVEAVNHWDEPDVLAEISREIGEPMRG
QDIAELEVRMEERGV

Sequences:

>Translated_335_residues
MDKMKIIMEKGTERLKRGFAKMVKGGVIMDVTNAEQARIAEEAGAVAVMALHKVPADIRKAGGVARMAPVEKIQEIMDAV
TIPVMAKVRIGHEAEARILEALGVDMIDESEVLTPADPFFHIYKKKFTVPFVCGARNLGEAVRRIWEGAAMIRTKGEAGT
GNIIEAVRHVRLVNENIRLIQRMTDEEIYGVAEKFAEPYLRLAFSVKEISGLPKRVLENEPIYEGFTYREIVDGLYKILL
EIKKLGRLPVVNFAAGGVATPADAALMMAMGMDGVFVGSGIFKSSNPPAMARAIVEAVNHWDEPDVLAEISREIGEPMRG
QDIAELEVRMEERGV
>Mature_335_residues
MDKMKIIMEKGTERLKRGFAKMVKGGVIMDVTNAEQARIAEEAGAVAVMALHKVPADIRKAGGVARMAPVEKIQEIMDAV
TIPVMAKVRIGHEAEARILEALGVDMIDESEVLTPADPFFHIYKKKFTVPFVCGARNLGEAVRRIWEGAAMIRTKGEAGT
GNIIEAVRHVRLVNENIRLIQRMTDEEIYGVAEKFAEPYLRLAFSVKEISGLPKRVLENEPIYEGFTYREIVDGLYKILL
EIKKLGRLPVVNFAAGGVATPADAALMMAMGMDGVFVGSGIFKSSNPPAMARAIVEAVNHWDEPDVLAEISREIGEPMRG
QDIAELEVRMEERGV

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring [H]

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323743, Length=327, Percent_Identity=54.1284403669725, Blast_Score=323, Evalue=4e-89,
Organism=Saccharomyces cerevisiae, GI6323996, Length=313, Percent_Identity=54.3130990415335, Blast_Score=300, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6321049, Length=313, Percent_Identity=53.9936102236422, Blast_Score=299, Evalue=4e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852
- InterPro:   IPR008867 [H]

Pfam domain/function: PF01680 SOR_SNZ; PF05690 ThiG [H]

EC number: NA

Molecular weight: Translated: 36901; Mature: 36901

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS01235 PDXS_SNZ_1 ; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKMKIIMEKGTERLKRGFAKMVKGGVIMDVTNAEQARIAEEAGAVAVMALHKVPADIRK
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCHHHHHHHHHCCHHHHH
AGGVARMAPVEKIQEIMDAVTIPVMAKVRIGHEAEARILEALGVDMIDESEVLTPADPFF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHH
HIYKKKFTVPFVCGARNLGEAVRRIWEGAAMIRTKGEAGTGNIIEAVRHVRLVNENIRLI
HHHHHHCCCEEEECCHHHHHHHHHHHCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHH
QRMTDEEIYGVAEKFAEPYLRLAFSVKEISGLPKRVLENEPIYEGFTYREIVDGLYKILL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHH
EIKKLGRLPVVNFAAGGVATPADAALMMAMGMDGVFVGSGIFKSSNPPAMARAIVEAVNH
HHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHC
WDEPDVLAEISREIGEPMRGQDIAELEVRMEERGV
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDKMKIIMEKGTERLKRGFAKMVKGGVIMDVTNAEQARIAEEAGAVAVMALHKVPADIRK
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCHHHHHHHHHCCHHHHH
AGGVARMAPVEKIQEIMDAVTIPVMAKVRIGHEAEARILEALGVDMIDESEVLTPADPFF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHH
HIYKKKFTVPFVCGARNLGEAVRRIWEGAAMIRTKGEAGTGNIIEAVRHVRLVNENIRLI
HHHHHHCCCEEEECCHHHHHHHHHHHCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHH
QRMTDEEIYGVAEKFAEPYLRLAFSVKEISGLPKRVLENEPIYEGFTYREIVDGLYKILL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHH
EIKKLGRLPVVNFAAGGVATPADAALMMAMGMDGVFVGSGIFKSSNPPAMARAIVEAVNH
HHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHC
WDEPDVLAEISREIGEPMRGQDIAELEVRMEERGV
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]