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The map label for this gene is 18977844

Identifier: 18977844

GI number: 18977844

Start: 1377755

End: 1378906

Strand: Reverse

Name: 18977844

Synonym: PF1472

Alternate gene names: NA

Gene position: 1378906-1377755 (Counterclockwise)

Preceding gene: 18977846

Following gene: 18977842

Centisome position: 72.26

GC content: 44.01

Gene sequence:

>1152_bases
ATGGAGTTTGAAGAGGCATTTAAAGAAGTTTACGAGCTTGTGAAACCTAAGTACAAGCTTTTCACAGCGGGTCCTGTTGC
CTGTTTCCCGGAAGTTCTCGAGATAATGAAAGTTCAGATGTTTAGCCACAGATCCAAAGAGTATAGGGCTGTTCACGTTG
ATACAGTTAAGAGGCTTAAAAACTTCCTCGAAGCGGAGAAGGGAGAAGTACTCCTAGTTCCAAGCTCTGGAACAGGAATA
ATGGAGGCTAGCATAAGAAACGGAGTTAGTAAAGGTGGAAAGGTTCTCGTAACTATAATTGGAGCATTTGGAAAAAGATA
CAAGGAAGTCGTTGAGTCTAATGGTAGAAAAGCTGTTGTTCTACAAAAAGACCCAGGGAAGGCTGTTAAGCCTGAAGAGC
TCGATGATGCACTAAGGAAGAATCCAGATGTTGAGGCCGTGACGATCACCTACAACGAAACCTCAACTGGAGTTCTCAAC
CCACTTCCAGAACTCGCAAAAGTTGCAAAGGAGCACGATAAGTTAGTGTTTGTCGATGCTGTTTCTGCTATGGGTGGGGC
AGATATAAAGTTTGACAAGTGGGATTTAGATGTAGTGTTCTCAAGCTCTCAGAAGGCCTTCGGTGTTCCTCCAGGATTGG
CTATTGGGGTCTTCAGCGAGAGGTTCTTGGAGATAGCTGAGAAAATGCCTGAAAGGGGATGGTACTTTGACATTCCACTC
TATGTGAAGTATCTGAAGGAAAAGGAGTCAACACCTTCGACCCCACCAATGCCTCAAGTATTTGGCCTAAACGTTGTTCT
CAGAATCATTGAAAAGATGGGTGGAAAAGAGAAGTGGCTAGAGATGTACGAAAAGAGAGCAAAGATGGTGAGGGAAGGAG
TTAAGGAAATCGGCCTTGGAATCCTTGCGGAGCCTGGATATGAGAGTCCAACGATTACAGCAGTACTTACTCCACCTGGG
ATAAAGGGTGATGAAGTGTATGAGGCAATGAGAAAGAGGGGCTTTGAGCTGGCAAAGGGTTATGGAAGCGTAAAGGAGAT
AACCTTTAGAATCGGTCACATGGGATATATGACTTTCGATGACATAAGAGAGATGCTTGATAACCTAAGAGAAGTAATTG
AGGAGCTTAAGAGAGAAAAAGGAATAGCTTAG

Upstream 100 bases:

>100_bases
TTTATTTAACACATCCTTATTTATTAATTGAAGCATGGCCAACTTCCCCACCATAGTATTTTTATACCTGTAAAATAACA
TTTACGTCGAGGTGGTTTAG

Downstream 100 bases:

>100_bases
CATATCTTTTCCAACTTTTCATCCTTTATTTCATATATTGCATTGACTTTTCTATGCCCGGTTTGTATGTCTCTGTACAA
TTCTATAACGACGTCAAACT

Product: aspartate/serine transaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MEFEEAFKEVYELVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRAVHVDTVKRLKNFLEAEKGEVLLVPSSGTGI
MEASIRNGVSKGGKVLVTIIGAFGKRYKEVVESNGRKAVVLQKDPGKAVKPEELDDALRKNPDVEAVTITYNETSTGVLN
PLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWDLDVVFSSSQKAFGVPPGLAIGVFSERFLEIAEKMPERGWYFDIPL
YVKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTITAVLTPPG
IKGDEVYEAMRKRGFELAKGYGSVKEITFRIGHMGYMTFDDIREMLDNLREVIEELKREKGIA

Sequences:

>Translated_383_residues
MEFEEAFKEVYELVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRAVHVDTVKRLKNFLEAEKGEVLLVPSSGTGI
MEASIRNGVSKGGKVLVTIIGAFGKRYKEVVESNGRKAVVLQKDPGKAVKPEELDDALRKNPDVEAVTITYNETSTGVLN
PLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWDLDVVFSSSQKAFGVPPGLAIGVFSERFLEIAEKMPERGWYFDIPL
YVKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTITAVLTPPG
IKGDEVYEAMRKRGFELAKGYGSVKEITFRIGHMGYMTFDDIREMLDNLREVIEELKREKGIA
>Mature_383_residues
MEFEEAFKEVYELVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRAVHVDTVKRLKNFLEAEKGEVLLVPSSGTGI
MEASIRNGVSKGGKVLVTIIGAFGKRYKEVVESNGRKAVVLQKDPGKAVKPEELDDALRKNPDVEAVTITYNETSTGVLN
PLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWDLDVVFSSSQKAFGVPPGLAIGVFSERFLEIAEKMPERGWYFDIPL
YVKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTITAVLTPPG
IKGDEVYEAMRKRGFELAKGYGSVKEITFRIGHMGYMTFDDIREMLDNLREVIEELKREKGIA

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=376, Percent_Identity=24.7340425531915, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17536281, Length=377, Percent_Identity=26.790450928382, Blast_Score=128, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6321079, Length=386, Percent_Identity=26.4248704663212, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17530823, Length=376, Percent_Identity=28.4574468085106, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 42926; Mature: 42926

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFEEAFKEVYELVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRAVHVDTVKRLK
CCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHH
NFLEAEKGEVLLVPSSGTGIMEASIRNGVSKGGKVLVTIIGAFGKRYKEVVESNGRKAVV
HHHHCCCCCEEEEECCCCCEEHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCEEEE
LQKDPGKAVKPEELDDALRKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDA
EECCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEE
VSAMGGADIKFDKWDLDVVFSSSQKAFGVPPGLAIGVFSERFLEIAEKMPERGWYFDIPL
HHHCCCCCCEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEHHH
YVKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLG
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
ILAEPGYESPTITAVLTPPGIKGDEVYEAMRKRGFELAKGYGSVKEITFRIGHMGYMTFD
EEECCCCCCCEEEEEECCCCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHCCCCCCHH
DIREMLDNLREVIEELKREKGIA
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEFEEAFKEVYELVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRAVHVDTVKRLK
CCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHH
NFLEAEKGEVLLVPSSGTGIMEASIRNGVSKGGKVLVTIIGAFGKRYKEVVESNGRKAVV
HHHHCCCCCEEEEECCCCCEEHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCEEEE
LQKDPGKAVKPEELDDALRKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDA
EECCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEE
VSAMGGADIKFDKWDLDVVFSSSQKAFGVPPGLAIGVFSERFLEIAEKMPERGWYFDIPL
HHHCCCCCCEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEHHH
YVKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLG
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
ILAEPGYESPTITAVLTPPGIKGDEVYEAMRKRGFELAKGYGSVKEITFRIGHMGYMTFD
EEECCCCCCCEEEEEECCCCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHCCCCCCHH
DIREMLDNLREVIEELKREKGIA
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]