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The map label for this gene is moaA [C]

Identifier: 18977826

GI number: 18977826

Start: 1360246

End: 1362012

Strand: Direct

Name: moaA [C]

Synonym: PF1454

Alternate gene names: 18977826

Gene position: 1360246-1362012 (Clockwise)

Preceding gene: 18977812

Following gene: 18977827

Centisome position: 71.28

GC content: 40.63

Gene sequence:

>1767_bases
ATGGCTGAGAATTTAAGTGCTGGGGAAGTTCCGAGTGGTGAGAAAGAGTTCGAAGCACTAACTAAAAGAATGCGGGAAAT
AATAGAATTTCCCGAGATAAGTGAAGAGGAATTTGAAGAAATGCTAAAAAATGCAAATCGAGGTTACGGAGAACCACTCC
CCCATAGAACCTACTCACTCTGTCCTGAGAGTAGGAGAGTAGTTCCCGCAGTCGTTTGGGAAAAGGATGGAATGGTCTGG
ATAACGAAGAAGTGTCCCGAAGGTATAATTACAGACTTATATTCTGAAGATGTTGACTTATATTATAGATTTCTACGATG
GAAGTTCGAAGATAAAAAGCTATTCTCAGTAAATGTTCCTAATACTGGAATTAACTGTCCCTTTGACTGTGGCCTTTGTG
CAAGACATAGATCTCACACAAACCTTCTCAACATAGTCCTCACAAACAGGTGTAATCTTAGCTGCTGGTACTGCTTCTTC
TATGCAAGAGAAGGAGAACCAGTATACGAGCCAACTCTAGAGCAAATAAGGATGATGCTAAGAAATGCAAAGAAGGAAAA
CCCAATTGGAGCAAACGCAGTCCAGTTCACTGGAGGAGAGCCCACTTTAAGAGACGATTTAATTGAAATAATAAAGATAG
CCAAAGAGGAAGGATACGACCACGTTCAGCTAAACACCGATGGAATAAGACTAGCATTTGAGCCTGAATTAGTTAAGAAG
ATAAGAGAAGCAGGAGTAAACACTCTATACTTGAGCTATGATGGAATGACGCCTCAAACTAACTGGAAGAATCACTGGGA
GATTCCACTGATATTTGAAAACGTGAGAAAAGCCGGTGGCCCCGGAATAGTTCTAGTCCCAACACTAATTAGAAATGTCA
ATGACCACGAAGCTGGGGCTATAATAAACTTCGGACTTAATCATCTTGACATAGTTAGAGGAGTAAACTTCCAGCCAATA
TCCCTAGTTGGTAGGGTACCCAAGAAGGAGAGGCAGAGGTTCAGAATAACGATTGCAGGAGCAATTAAGAAGATAGAAGA
GCAAACAAATGGGGCTATATCTAGAGATGACTGGTACCCAATTCCAATAGCGGGTTACATAGCTAGGTTCTTCGAAGCAT
TTACAGGAAAGCACTACTATATGACCAGCCACTATGCCTGTGGAGCTGCAACCTATGTTTTTCTCGACAAAGAGGAGAAG
AAGGTTATCCCAATTCCCAGGTTCATAGATGTAGAAGGATTTGTTGAATTCTTAGTTGAGAAGGCTGAAGAAATAGAAAG
AGCAAGATTCAAAGGTTTAGCAAAGCTAAAAGCAATAGGAGAGACAGTCTTTATAAAATTCAAGCAGTTCTATGACGAAA
AGTATGCACCAAAAGGGTTAGATGTACTTGGACTAATTAAGAATGCATTCATGCATGGAAACTATGATGCCTTAGGACAG
TTCCACACTAAGACCCTCTTCCTGGGAATGATGCACTTCATGGATGAGTACAACTACGATGTGGAGAGAGTTGAAAGATG
TGTAATTCACTATGCAATGCCCGATGGAAGGATAGTTCCATTCTGTACCTTTAATGTAATACCAGAAATATATAGAGACA
AAGTCCAGAGACAATTTAGTTATTCCTGGGAAGAGTGGAAGAAGCTACACCCAGATTGGGACTATAAGAAGGACAAGTAC
TTCAGGACAAGAGAATTCGTCGAAAAAATGAAGAACAGCGAGCTCTACAGGAAGACTTACATTGACATAGTCAACTACTT
TGAGTGA

Upstream 100 bases:

>100_bases
GAGATTATGAAATCAAAATTTCATACATATGAAAATTTAGTTTCAAATATAGGCAAAACCTTTTATAGGGAGAAGGGGGT
ATAGGTCTTCAGGTGGTAAC

Downstream 100 bases:

>100_bases
GGTGGTAGGATGAAGTGGATAAAATTCACGACTAACTTAACTCCAGAAGAAGCAAAAATCGTCCAGTATGAACTCTCAAC
GAGAGATGAATTTTACAGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 587

Protein sequence:

>588_residues
MAENLSAGEVPSGEKEFEALTKRMREIIEFPEISEEEFEEMLKNANRGYGEPLPHRTYSLCPESRRVVPAVVWEKDGMVW
ITKKCPEGIITDLYSEDVDLYYRFLRWKFEDKKLFSVNVPNTGINCPFDCGLCARHRSHTNLLNIVLTNRCNLSCWYCFF
YAREGEPVYEPTLEQIRMMLRNAKKENPIGANAVQFTGGEPTLRDDLIEIIKIAKEEGYDHVQLNTDGIRLAFEPELVKK
IREAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPI
SLVGRVPKKERQRFRITIAGAIKKIEEQTNGAISRDDWYPIPIAGYIARFFEAFTGKHYYMTSHYACGAATYVFLDKEEK
KVIPIPRFIDVEGFVEFLVEKAEEIERARFKGLAKLKAIGETVFIKFKQFYDEKYAPKGLDVLGLIKNAFMHGNYDALGQ
FHTKTLFLGMMHFMDEYNYDVERVERCVIHYAMPDGRIVPFCTFNVIPEIYRDKVQRQFSYSWEEWKKLHPDWDYKKDKY
FRTREFVEKMKNSELYRKTYIDIVNYFE

Sequences:

>Translated_588_residues
MAENLSAGEVPSGEKEFEALTKRMREIIEFPEISEEEFEEMLKNANRGYGEPLPHRTYSLCPESRRVVPAVVWEKDGMVW
ITKKCPEGIITDLYSEDVDLYYRFLRWKFEDKKLFSVNVPNTGINCPFDCGLCARHRSHTNLLNIVLTNRCNLSCWYCFF
YAREGEPVYEPTLEQIRMMLRNAKKENPIGANAVQFTGGEPTLRDDLIEIIKIAKEEGYDHVQLNTDGIRLAFEPELVKK
IREAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPI
SLVGRVPKKERQRFRITIAGAIKKIEEQTNGAISRDDWYPIPIAGYIARFFEAFTGKHYYMTSHYACGAATYVFLDKEEK
KVIPIPRFIDVEGFVEFLVEKAEEIERARFKGLAKLKAIGETVFIKFKQFYDEKYAPKGLDVLGLIKNAFMHGNYDALGQ
FHTKTLFLGMMHFMDEYNYDVERVERCVIHYAMPDGRIVPFCTFNVIPEIYRDKVQRQFSYSWEEWKKLHPDWDYKKDKY
FRTREFVEKMKNSELYRKTYIDIVNYFE
>Mature_587_residues
AENLSAGEVPSGEKEFEALTKRMREIIEFPEISEEEFEEMLKNANRGYGEPLPHRTYSLCPESRRVVPAVVWEKDGMVWI
TKKCPEGIITDLYSEDVDLYYRFLRWKFEDKKLFSVNVPNTGINCPFDCGLCARHRSHTNLLNIVLTNRCNLSCWYCFFY
AREGEPVYEPTLEQIRMMLRNAKKENPIGANAVQFTGGEPTLRDDLIEIIKIAKEEGYDHVQLNTDGIRLAFEPELVKKI
REAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPIS
LVGRVPKKERQRFRITIAGAIKKIEEQTNGAISRDDWYPIPIAGYIARFFEAFTGKHYYMTSHYACGAATYVFLDKEEKK
VIPIPRFIDVEGFVEFLVEKAEEIERARFKGLAKLKAIGETVFIKFKQFYDEKYAPKGLDVLGLIKNAFMHGNYDALGQF
HTKTLFLGMMHFMDEYNYDVERVERCVIHYAMPDGRIVPFCTFNVIPEIYRDKVQRQFSYSWEEWKKLHPDWDYKKDKYF
RTREFVEKMKNSELYRKTYIDIVNYFE

Specific function: Together With Moac, Is Involved In The Conversion Of A Guanosine Derivative (Gxp) Into Molybdopterin Precursor Z. [C]

COG id: COG1964

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI116734668, Length=183, Percent_Identity=29.5081967213115, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI22027536, Length=137, Percent_Identity=32.1167883211679, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561210, Length=195, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 68722; Mature: 68590

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENLSAGEVPSGEKEFEALTKRMREIIEFPEISEEEFEEMLKNANRGYGEPLPHRTYSL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHC
CPESRRVVPAVVWEKDGMVWITKKCPEGIITDLYSEDVDLYYRFLRWKFEDKKLFSVNVP
CCCCCCEEEEEEEECCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHEECCCEEEEEECC
NTGINCPFDCGLCARHRSHTNLLNIVLTNRCNLSCWYCFFYAREGEPVYEPTLEQIRMML
CCCCCCCCCCCHHHHCCCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCHHHHHHHHHHH
RNAKKENPIGANAVQFTGGEPTLRDDLIEIIKIAKEEGYDHVQLNTDGIRLAFEPELVKK
HHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECHHHHHH
IREAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGA
HHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEHHHHHCCCCCCCCCE
IINFGLNHLDIVRGVNFQPISLVGRVPKKERQRFRITIAGAIKKIEEQTNGAISRDDWYP
EEECCCCHHHHHHCCCCCCHHHHCCCCHHHHHEEEEEHHHHHHHHHHHHCCCCCCCCCCC
IPIAGYIARFFEAFTGKHYYMTSHYACGAATYVFLDKEEKKVIPIPRFIDVEGFVEFLVE
CCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEECCCCCCCCCCCEECHHHHHHHHHH
KAEEIERARFKGLAKLKAIGETVFIKFKQFYDEKYAPKGLDVLGLIKNAFMHGNYDALGQ
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHH
FHTKTLFLGMMHFMDEYNYDVERVERCVIHYAMPDGRIVPFCTFNVIPEIYRDKVQRQFS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEECCCCCEEEEEEHHHHHHHHHHHHHHHHC
YSWEEWKKLHPDWDYKKDKYFRTREFVEKMKNSELYRKTYIDIVNYFE
CCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AENLSAGEVPSGEKEFEALTKRMREIIEFPEISEEEFEEMLKNANRGYGEPLPHRTYSL
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHC
CPESRRVVPAVVWEKDGMVWITKKCPEGIITDLYSEDVDLYYRFLRWKFEDKKLFSVNVP
CCCCCCEEEEEEEECCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHEECCCEEEEEECC
NTGINCPFDCGLCARHRSHTNLLNIVLTNRCNLSCWYCFFYAREGEPVYEPTLEQIRMML
CCCCCCCCCCCHHHHCCCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCHHHHHHHHHHH
RNAKKENPIGANAVQFTGGEPTLRDDLIEIIKIAKEEGYDHVQLNTDGIRLAFEPELVKK
HHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECHHHHHH
IREAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGA
HHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEHHHHHCCCCCCCCCE
IINFGLNHLDIVRGVNFQPISLVGRVPKKERQRFRITIAGAIKKIEEQTNGAISRDDWYP
EEECCCCHHHHHHCCCCCCHHHHCCCCHHHHHEEEEEHHHHHHHHHHHHCCCCCCCCCCC
IPIAGYIARFFEAFTGKHYYMTSHYACGAATYVFLDKEEKKVIPIPRFIDVEGFVEFLVE
CCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEECCCCCCCCCCCEECHHHHHHHHHH
KAEEIERARFKGLAKLKAIGETVFIKFKQFYDEKYAPKGLDVLGLIKNAFMHGNYDALGQ
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHH
FHTKTLFLGMMHFMDEYNYDVERVERCVIHYAMPDGRIVPFCTFNVIPEIYRDKVQRQFS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEECCCCCEEEEEEHHHHHHHHHHHHHHHHC
YSWEEWKKLHPDWDYKKDKYFRTREFVEKMKNSELYRKTYIDIVNYFE
CCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]