BacMap

Definition	Pyrococcus furiosus DSM 3638, complete genome.
Accession	NC_003413
Length	1,908,256

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The map label for this gene is sufC [H]

Identifier: 18977659

GI number: 18977659

Start: 1214251

End: 1214982

Strand: Reverse

Name: sufC [H]

Synonym: PF1287

Alternate gene names: 18977659

Gene position: 1214982-1214251 (Counterclockwise)

Preceding gene: 18977660

Following gene: 18977658

Centisome position: 63.67

GC content: 37.84

Gene sequence:

>732_bases
ATGCTAAAAGTAGAGAATCTATGGGTTAAAGTCGAAGATAAAGAAATACTCAAGGGCATTAACTTAAATATTGGAGAGAA
CGAACTCCACGTAGTAATGGGACCTAATGGAAGTGGAAAATCGACCTTAGCACTAACAATCGCTGGCCATCCCAAGTATA
AAGTTATACAGGGGAGTATACTATTCGAAGGAGAGGAAATAACGTCGCTTCCTCCAGAGGAACGTGTAAAAAAAGGAATA
TTTCTGAGCTTTCAACACCCTGTAGAAGTAGATGGAGTAAAGATAATTCATTTCCTACAGAGAATTCTCAAAAATCTAAA
AGGAATGGACGAGATAAAAGCATATGAAGCTATTTACACGGCTATCAAGGAACTCGGTCTAGATGAATCAATTCTAACGA
GGTTTCTAAATGTAGGATTTTCAGGAGGCGAAAGAAAGAAATTAGAGATGCTTCAGGCTTATTTAGTAGAACCTAAACTT
TTGATTCTTGATGAACCTGACAGTGGGGTTGACGTCGATTCTTTAAAGACAATAGCAAAAATTATACGAAGACTTTACGA
ACGGGGAACGTCAGTGCTTTTGATTACCCACTACGGAAGGATATTGGAGTATCTAAATCCAACAAAAGTCCACGTAATAA
AAAATGGAAAAATAGTAGCCTCAGGAAGCATTGATCTTGTCAAAATTATAGAAGAGAGAGGATATTCGGCGGTGGGGGAC
AATGAAGAGTAA

Upstream 100 bases:

>100_bases
GTCTTCTGTAACCCTCTATATTTTACCCAAATTTGGGTAAGAAAGACTTAAAAATGTATATTTTTACTCAAAATTAGACA
AGTTAGGAATGGTGATCACC

Downstream 100 bases:

>100_bases
AAGTCACTTAGAAGAAATTCTAAAAGCGGGATCCTTAGAAGAAATCTTAGGTACTGCCGTTCCGTATCCTAAAGAGATTG
AGATAAAGGGGAAAATTAGT

Product: putative ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MLKVENLWVKVEDKEILKGINLNIGENELHVVMGPNGSGKSTLALTIAGHPKYKVIQGSILFEGEEITSLPPEERVKKGI
FLSFQHPVEVDGVKIIHFLQRILKNLKGMDEIKAYEAIYTAIKELGLDESILTRFLNVGFSGGERKKLEMLQAYLVEPKL
LILDEPDSGVDVDSLKTIAKIIRRLYERGTSVLLITHYGRILEYLNPTKVHVIKNGKIVASGSIDLVKIIEERGYSAVGD
NEE

Sequences:

>Translated_243_residues
MLKVENLWVKVEDKEILKGINLNIGENELHVVMGPNGSGKSTLALTIAGHPKYKVIQGSILFEGEEITSLPPEERVKKGI
FLSFQHPVEVDGVKIIHFLQRILKNLKGMDEIKAYEAIYTAIKELGLDESILTRFLNVGFSGGERKKLEMLQAYLVEPKL
LILDEPDSGVDVDSLKTIAKIIRRLYERGTSVLLITHYGRILEYLNPTKVHVIKNGKIVASGSIDLVKIIEERGYSAVGD
NEE
>Mature_243_residues
MLKVENLWVKVEDKEILKGINLNIGENELHVVMGPNGSGKSTLALTIAGHPKYKVIQGSILFEGEEITSLPPEERVKKGI
FLSFQHPVEVDGVKIIHFLQRILKNLKGMDEIKAYEAIYTAIKELGLDESILTRFLNVGFSGGERKKLEMLQAYLVEPKL
LILDEPDSGVDVDSLKTIAKIIRRLYERGTSVLLITHYGRILEYLNPTKVHVIKNGKIVASGSIDLVKIIEERGYSAVGD
NEE

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI116734710, Length=226, Percent_Identity=27.8761061946903, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI62526033, Length=237, Percent_Identity=26.1603375527426, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI153792144, Length=209, Percent_Identity=26.7942583732057, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI21729873, Length=216, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI15149474, Length=216, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI45446740, Length=225, Percent_Identity=27.5555555555556, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI47078218, Length=225, Percent_Identity=27.5555555555556, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI21536376, Length=213, Percent_Identity=27.6995305164319, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI105990541, Length=206, Percent_Identity=26.6990291262136, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787972, Length=241, Percent_Identity=45.2282157676349, Blast_Score=221, Evalue=4e-59,
Organism=Escherichia coli, GI1789891, Length=217, Percent_Identity=29.4930875576037, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1786563, Length=200, Percent_Identity=32.5, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788472, Length=216, Percent_Identity=30.0925925925926, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1788506, Length=238, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786698, Length=203, Percent_Identity=29.5566502463054, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789864, Length=243, Percent_Identity=23.8683127572016, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1787500, Length=227, Percent_Identity=27.3127753303965, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1789593, Length=228, Percent_Identity=27.1929824561404, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786319, Length=215, Percent_Identity=27.906976744186, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1787029, Length=230, Percent_Identity=24.3478260869565, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI87082267, Length=184, Percent_Identity=28.2608695652174, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1787112, Length=222, Percent_Identity=29.2792792792793, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790162, Length=205, Percent_Identity=27.8048780487805, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87081834, Length=207, Percent_Identity=25.6038647342995, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994883, Length=209, Percent_Identity=29.1866028708134, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787712, Length=211, Percent_Identity=26.0663507109005, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789991, Length=253, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786975, Length=206, Percent_Identity=28.6407766990291, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787105, Length=223, Percent_Identity=26.457399103139, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1786654, Length=217, Percent_Identity=26.2672811059908, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787792, Length=223, Percent_Identity=25.1121076233184, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081782, Length=230, Percent_Identity=25.2173913043478, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=225, Percent_Identity=28.8888888888889, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71996809, Length=217, Percent_Identity=26.2672811059908, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI212646699, Length=220, Percent_Identity=26.3636363636364, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193211015, Length=217, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=217, Percent_Identity=25.8064516129032, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=216, Percent_Identity=26.8518518518519, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71983516, Length=229, Percent_Identity=26.6375545851528, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=229, Percent_Identity=26.6375545851528, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71983523, Length=229, Percent_Identity=26.6375545851528, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=224, Percent_Identity=25, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193209708, Length=223, Percent_Identity=27.3542600896861, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193202349, Length=221, Percent_Identity=25.3393665158371, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=221, Percent_Identity=24.8868778280543, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6323217, Length=223, Percent_Identity=30.9417040358744, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324498, Length=243, Percent_Identity=29.2181069958848, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI221500365, Length=220, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007184, Length=220, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI161076682, Length=228, Percent_Identity=26.7543859649123, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161076684, Length=228, Percent_Identity=26.7543859649123, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24581617, Length=228, Percent_Identity=26.7543859649123, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24581615, Length=228, Percent_Identity=26.7543859649123, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24643674, Length=237, Percent_Identity=23.6286919831224, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17647959, Length=220, Percent_Identity=29.0909090909091, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920532, Length=232, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24580930, Length=232, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24666092, Length=214, Percent_Identity=26.6355140186916, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI85816269, Length=233, Percent_Identity=26.1802575107296, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24580553, Length=233, Percent_Identity=26.1802575107296, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI85724864, Length=233, Percent_Identity=26.1802575107296, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24580555, Length=233, Percent_Identity=26.1802575107296, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281363262, Length=217, Percent_Identity=28.110599078341, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28574533, Length=218, Percent_Identity=26.605504587156, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24653245, Length=217, Percent_Identity=28.110599078341, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI28574744, Length=226, Percent_Identity=24.3362831858407, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24648314, Length=230, Percent_Identity=24.3478260869565, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI116007328, Length=212, Percent_Identity=28.7735849056604, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28574150, Length=212, Percent_Identity=28.7735849056604, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27160; Mature: 27160

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVENLWVKVEDKEILKGINLNIGENELHVVMGPNGSGKSTLALTIAGHPKYKVIQGSI
CEEEEEEEEEECCHHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCEEEEEEEE
LFEGEEITSLPPEERVKKGIFLSFQHPVEVDGVKIIHFLQRILKNLKGMDEIKAYEAIYT
EECCCHHCCCCCHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AIKELGLDESILTRFLNVGFSGGERKKLEMLQAYLVEPKLLILDEPDSGVDVDSLKTIAK
HHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHH
IIRRLYERGTSVLLITHYGRILEYLNPTKVHVIKNGKIVASGSIDLVKIIEERGYSAVGD
HHHHHHHCCCCEEEEEHHHHHHHHCCCCEEEEEECCEEEEECCCHHHHHHHHCCCCCCCC
NEE
CCC
>Mature Secondary Structure
MLKVENLWVKVEDKEILKGINLNIGENELHVVMGPNGSGKSTLALTIAGHPKYKVIQGSI
CEEEEEEEEEECCHHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCEEEEEEEE
LFEGEEITSLPPEERVKKGIFLSFQHPVEVDGVKIIHFLQRILKNLKGMDEIKAYEAIYT
EECCCHHCCCCCHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AIKELGLDESILTRFLNVGFSGGERKKLEMLQAYLVEPKLLILDEPDSGVDVDSLKTIAK
HHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHH
IIRRLYERGTSVLLITHYGRILEYLNPTKVHVIKNGKIVASGSIDLVKIIEERGYSAVGD
HHHHHHHCCCCEEEEEHHHHHHHHCCCCEEEEEECCEEEEECCCHHHHHHHHCCCCCCCC
NEE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]