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The map label for this gene is ycfF [C]

Identifier: 18977479

GI number: 18977479

Start: 1054030

End: 1054470

Strand: Reverse

Name: ycfF [C]

Synonym: PF1107

Alternate gene names: 18977479

Gene position: 1054470-1054030 (Counterclockwise)

Preceding gene: 18977483

Following gene: 18977478

Centisome position: 55.26

GC content: 42.63

Gene sequence:

>441_bases
ATGCCGTGTCCATTTTGCAATCCTCCAGCCGAGAACATTGTCTATGAAGATGATAAAATAAGAATTCTCTTAGACAGCTT
TCCCGCTAATCCTGGACATCTTTTAGTCGTCCCAAAGAGGCACATAACCAACATTGAGGGGCTTAATGAGGAGGAAAAAG
TTATGCTTATGAAGGGAGTTGAGATGGCAATCAAAGCCTTGAAAGAAGCATTAAATCCAGATGGATTTAATGTGGGAATA
AATTTGGGAAAGGCTGCTGGCCAAACGGTTTCTCATCTTCATGTCCATGTTATTCCCAGGTACAAGGGAGATTGTAAGCA
TCCTGAGGGTGGTATCAGAAAGGCCGTTTTAAATGCGAAGGATGAGAACTTAGGAAGGCAGGATAAGAGGCTTGAAAGTA
AGTACGTCGAAATCCTGAGGGGGCTACTTAATGAGAAGTAG

Upstream 100 bases:

>100_bases
ACCGCGGGACCCTACTGTGAACCCCAATGGATTTTCATCAGATATGGATTTATAAACTTTTCGCGATGCCTATTTAAGCA
TATTCACATCTAATCCTTTC

Downstream 100 bases:

>100_bases
CATAGTTTTTGGAGCTCTAGGGGCTGTAATCTTGATTTTAGTTAGTCTAACAGTTAAGCCGTTCTTCTCTTCCTTTTTCT
TTGCATTTGTAACAGCTTAT

Product: hit family protein

Products: NA

Alternate protein names: ATP adenylyltransferase; Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase; AP,A phosphorylase [H]

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MPCPFCNPPAENIVYEDDKIRILLDSFPANPGHLLVVPKRHITNIEGLNEEEKVMLMKGVEMAIKALKEALNPDGFNVGI
NLGKAAGQTVSHLHVHVIPRYKGDCKHPEGGIRKAVLNAKDENLGRQDKRLESKYVEILRGLLNEK

Sequences:

>Translated_146_residues
MPCPFCNPPAENIVYEDDKIRILLDSFPANPGHLLVVPKRHITNIEGLNEEEKVMLMKGVEMAIKALKEALNPDGFNVGI
NLGKAAGQTVSHLHVHVIPRYKGDCKHPEGGIRKAVLNAKDENLGRQDKRLESKYVEILRGLLNEK
>Mature_145_residues
PCPFCNPPAENIVYEDDKIRILLDSFPANPGHLLVVPKRHITNIEGLNEEEKVMLMKGVEMAIKALKEALNPDGFNVGIN
LGKAAGQTVSHLHVHVIPRYKGDCKHPEGGIRKAVLNAKDENLGRQDKRLESKYVEILRGLLNEK

Specific function: Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues [H]

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320511, Length=94, Percent_Identity=36.1702127659575, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: =2.7.7.53 [H]

Molecular weight: Translated: 16281; Mature: 16150

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCPFCNPPAENIVYEDDKIRILLDSFPANPGHLLVVPKRHITNIEGLNEEEKVMLMKGV
CCCCCCCCCCCCEEECCCCEEEEEECCCCCCCEEEEECCHHHCCCCCCCHHHHHHHHHHH
EMAIKALKEALNPDGFNVGINLGKAAGQTVSHLHVHVIPRYKGDCKHPEGGIRKAVLNAK
HHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHCCC
DENLGRQDKRLESKYVEILRGLLNEK
CCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PCPFCNPPAENIVYEDDKIRILLDSFPANPGHLLVVPKRHITNIEGLNEEEKVMLMKGV
CCCCCCCCCCCEEECCCCEEEEEECCCCCCCEEEEECCHHHCCCCCCCHHHHHHHHHHH
EMAIKALKEALNPDGFNVGINLGKAAGQTVSHLHVHVIPRYKGDCKHPEGGIRKAVLNAK
HHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHCCC
DENLGRQDKRLESKYVEILRGLLNEK
CCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]