Click here to switch to the map view.

The map label for this gene is tldD [C]

Identifier: 18977448

GI number: 18977448

Start: 1026067

End: 1027488

Strand: Direct

Name: tldD [C]

Synonym: PF1076

Alternate gene names: 18977448

Gene position: 1026067-1027488 (Clockwise)

Preceding gene: 18977447

Following gene: 18977449

Centisome position: 53.77

GC content: 45.78

Gene sequence:

>1422_bases
ATGCATGACCTAGTTGAGTTCGCCGTTAACCGTGCTCTGGAGCTCGGTGCCGATTATGCAGAAGCAAGGTTCGAAGAAAA
GCAGGGAACTTTTCTTGCAATGAAAAACGGAAATCCAGAAGGACTAGGAATCCTAGCAGATAAGGGAATTGGAGTGAGAG
TCCTAGTAAATGGGGGAATGGGATTTGCCAGCACAAATGTGCTCACAAAGGAGAGCATAGCGAGGACTGTGGAGAGAGCA
ATAAAGATGGCAAAGGCCGCAGCAAAGCTAAGAAAAGAGCCAATAAAATTTAGCGAAGAAGACTTCCACGAAGTGTACTA
TGAGGTAAAGATGAGAAAGGACATAAGAGATGTCCCGCCAGAGGAGAAGTTGGAAATTCTGAAGAAAATAGAAGAGGAAG
TAACATCAACAAACGCTAACGTACCAATGAGATTCCTAAGATACAATGACTTCATTTGGCATAAGATATTCATGAACAAC
GAGGGTGCTTTGGTGGAGAGTGTAATTCCCAGGGTCTCGGTAATGTATAATCTAGTTGTATTTGAGAACGGCCAGATGGA
GCAGGCCCCATTCGTTCAGAGGGCATTCTCCGGAGGATTAGAACTCATAGAGAAGGACGAACCCTGGGAAAGGGCTAGGA
GAGAGGTAGAGACGCTAAAGAAAATTATAGTAGAGGGTAAAAGACCCCCAGAGGGGAAAGTAGACCTAGTTTTAGCACCA
GAAGTCGTTGGAATTGCAGTTCACGAGAGCGTTGGGCACCCGTATGAGCTTGACAGAATAATGGGAAGAGAAGCCGCACA
GGCAGGAGAGAGCTTCGTAAAGCCAGACATGCTGGGTGAGAGAATCGGAAGTGACGTGGTTACGGTAATTGAAGACCCCA
CAATTCCAAACAGCTGGGGATTCTATCTGTATGATGATGAGGGAGTTAAGGCAAGACCCAGGTACTTGATAAGGAATGGA
ATTATAACAGAGTTTTTAATGAACAGAGAATATGCCGCAAAGCTCGGCCTTAAGTCAAATGCAGCTGCGAGAGCAATAAA
TTACAATAGAGAGCCAATTATCAGAATGGCCAACACATACCTAGCTCCTGGGGATTACACATTCGAGGAGCTAATCGAGG
ACGTAAAGCTCGGTGTTTACATGGTGTCATTTAACGAGTGGAACATCGATGATAGGAGATATCAGCAGAGATACATTGGA
AGGGAAGCCTATCTCATAGAGAATGGAGAGATAAAGTATCCAGTAAGGAGGCCCATTCTAGAGATTACTACAAAAGGTCT
CTGGAGCAGTGTTGACGCCGTTGGCAGGGAGGTTGAGTTCTTCCCAGGAACATGTGGAAAAGGAGAACCAGGACAGGGAG
TCCCAGTGTGGATGGGAGGAGCTCATGCGAGATTGAGGGATATTCCACTAAGAAGGCCTTGA

Upstream 100 bases:

>100_bases
TTAGGATGCTGGTCTAGTATCAATAAGACAAACATCGAAACGAAAAGATTTTTATACTTATGTTTCATCAATATTATTGC
ATTAAGGAGGTGTTGAGGAC

Downstream 100 bases:

>100_bases
GGTGAGGGAAAATGTTTGATGTTAACGAGCTCATACTTAAAAAGGCAAAGGAAATGGGATTTGGAGATGTTGTAGTCCTC
AGTTACGAAACTAACAGGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MHDLVEFAVNRALELGADYAEARFEEKQGTFLAMKNGNPEGLGILADKGIGVRVLVNGGMGFASTNVLTKESIARTVERA
IKMAKAAAKLRKEPIKFSEEDFHEVYYEVKMRKDIRDVPPEEKLEILKKIEEEVTSTNANVPMRFLRYNDFIWHKIFMNN
EGALVESVIPRVSVMYNLVVFENGQMEQAPFVQRAFSGGLELIEKDEPWERARREVETLKKIIVEGKRPPEGKVDLVLAP
EVVGIAVHESVGHPYELDRIMGREAAQAGESFVKPDMLGERIGSDVVTVIEDPTIPNSWGFYLYDDEGVKARPRYLIRNG
IITEFLMNREYAAKLGLKSNAAARAINYNREPIIRMANTYLAPGDYTFEELIEDVKLGVYMVSFNEWNIDDRRYQQRYIG
REAYLIENGEIKYPVRRPILEITTKGLWSSVDAVGREVEFFPGTCGKGEPGQGVPVWMGGAHARLRDIPLRRP

Sequences:

>Translated_473_residues
MHDLVEFAVNRALELGADYAEARFEEKQGTFLAMKNGNPEGLGILADKGIGVRVLVNGGMGFASTNVLTKESIARTVERA
IKMAKAAAKLRKEPIKFSEEDFHEVYYEVKMRKDIRDVPPEEKLEILKKIEEEVTSTNANVPMRFLRYNDFIWHKIFMNN
EGALVESVIPRVSVMYNLVVFENGQMEQAPFVQRAFSGGLELIEKDEPWERARREVETLKKIIVEGKRPPEGKVDLVLAP
EVVGIAVHESVGHPYELDRIMGREAAQAGESFVKPDMLGERIGSDVVTVIEDPTIPNSWGFYLYDDEGVKARPRYLIRNG
IITEFLMNREYAAKLGLKSNAAARAINYNREPIIRMANTYLAPGDYTFEELIEDVKLGVYMVSFNEWNIDDRRYQQRYIG
REAYLIENGEIKYPVRRPILEITTKGLWSSVDAVGREVEFFPGTCGKGEPGQGVPVWMGGAHARLRDIPLRRP
>Mature_473_residues
MHDLVEFAVNRALELGADYAEARFEEKQGTFLAMKNGNPEGLGILADKGIGVRVLVNGGMGFASTNVLTKESIARTVERA
IKMAKAAAKLRKEPIKFSEEDFHEVYYEVKMRKDIRDVPPEEKLEILKKIEEEVTSTNANVPMRFLRYNDFIWHKIFMNN
EGALVESVIPRVSVMYNLVVFENGQMEQAPFVQRAFSGGLELIEKDEPWERARREVETLKKIIVEGKRPPEGKVDLVLAP
EVVGIAVHESVGHPYELDRIMGREAAQAGESFVKPDMLGERIGSDVVTVIEDPTIPNSWGFYLYDDEGVKARPRYLIRNG
IITEFLMNREYAAKLGLKSNAAARAINYNREPIIRMANTYLAPGDYTFEELIEDVKLGVYMVSFNEWNIDDRRYQQRYIG
REAYLIENGEIKYPVRRPILEITTKGLWSSVDAVGREVEFFPGTCGKGEPGQGVPVWMGGAHARLRDIPLRRP

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=419, Percent_Identity=24.8210023866348, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1790682, Length=453, Percent_Identity=24.9448123620309, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 53678; Mature: 53678

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDLVEFAVNRALELGADYAEARFEEKQGTFLAMKNGNPEGLGILADKGIGVRVLVNGGM
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCEEEEEECCC
GFASTNVLTKESIARTVERAIKMAKAAAKLRKEPIKFSEEDFHEVYYEVKMRKDIRDVPP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
EEKLEILKKIEEEVTSTNANVPMRFLRYNDFIWHKIFMNNEGALVESVIPRVSVMYNLVV
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHEEEEE
FENGQMEQAPFVQRAFSGGLELIEKDEPWERARREVETLKKIIVEGKRPPEGKVDLVLAP
EECCCCCCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
EVVGIAVHESVGHPYELDRIMGREAAQAGESFVKPDMLGERIGSDVVTVIEDPTIPNSWG
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCCC
FYLYDDEGVKARPRYLIRNGIITEFLMNREYAAKLGLKSNAAARAINYNREPIIRMANTY
EEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHCCCCCCHHHHHHCCE
LAPGDYTFEELIEDVKLGVYMVSFNEWNIDDRRYQQRYIGREAYLIENGEIKYPVRRPIL
ECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCEECHHHCCHH
EITTKGLWSSVDAVGREVEFFPGTCGKGEPGQGVPVWMGGAHARLRDIPLRRP
HHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCEEEECCCCHHHHCCCCCCC
>Mature Secondary Structure
MHDLVEFAVNRALELGADYAEARFEEKQGTFLAMKNGNPEGLGILADKGIGVRVLVNGGM
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCEEEEEECCC
GFASTNVLTKESIARTVERAIKMAKAAAKLRKEPIKFSEEDFHEVYYEVKMRKDIRDVPP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
EEKLEILKKIEEEVTSTNANVPMRFLRYNDFIWHKIFMNNEGALVESVIPRVSVMYNLVV
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHEEEEE
FENGQMEQAPFVQRAFSGGLELIEKDEPWERARREVETLKKIIVEGKRPPEGKVDLVLAP
EECCCCCCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
EVVGIAVHESVGHPYELDRIMGREAAQAGESFVKPDMLGERIGSDVVTVIEDPTIPNSWG
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCCC
FYLYDDEGVKARPRYLIRNGIITEFLMNREYAAKLGLKSNAAARAINYNREPIIRMANTY
EEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHCCCCCCHHHHHHCCE
LAPGDYTFEELIEDVKLGVYMVSFNEWNIDDRRYQQRYIGREAYLIENGEIKYPVRRPIL
ECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCEECHHHCCHH
EITTKGLWSSVDAVGREVEFFPGTCGKGEPGQGVPVWMGGAHARLRDIPLRRP
HHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCEEEECCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]