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The map label for this gene is yafV [C]

Identifier: 18977389

GI number: 18977389

Start: 973527

End: 974315

Strand: Reverse

Name: yafV [C]

Synonym: PF1017

Alternate gene names: 18977389

Gene position: 974315-973527 (Counterclockwise)

Preceding gene: 18977394

Following gene: 18977388

Centisome position: 51.06

GC content: 40.3

Gene sequence:

>789_bases
ATGGTTAAGGTTGCCTATGTGCAAATGGAACCTAAAATACTTGAACTTGACAAGAATCTCTCAAAGGCTGAAAAATTAGT
AAAAGAGGCAGCAAAGAGAGAAGCTAAACTCATAGTTCTCCCTGAGCTTTTTGACACTGGATACAATTTTGAAAGCAGAG
ATGAAGTATTTGAAATAGCTCAAAGAATACCTGAAGGAGAAACAACTACCTTTCTCATGGACCTTGCTGGAGATTTAGAG
GTCTACATTGTGGCAGGTACTGCTGAAAAATATAACGATCGCTTATACAATTCAGCAGTTCTCGTAGGTCCCACTGGCTA
CCTGGGAAAATATAGAAAGATCCACCTCTTTTATAGGGAGAAGGTATTCTTTGACCCGGGGGATCTTGGCTTTAATGTAT
TTGACCTGGGGTTTATAAGAGTAGGAATTATGATATGCTTCGATTGGTTTTTCCCTGAATCTGCCAGAACTCTTGCCTTG
AAAGGAGCGGATATTATAGCTCATCCAGCCAATTTAGTTATGCCCTATGCTCCTAGAGCCATGCCCATAAGGGCTCTTGA
AAACAGGGTATATATAATAACTGCAGATAGAGTAGGAGAAGAAAGAGGGCTAAGATTCATTGGAAAAAGCTTGATTGCCT
CTCCAAAAGCGGAAGTTCTAGCCATGGGAAGCGAAACTGAAGAAGAGGTGGGAGTTGCAGAAGTAGACATCTCATTAGTA
AGAAACAAGAGGATAAACGATTTAAATGATATCTTCAAGGATAGGAGGCCGGAATATTACTTTAGGTGA

Upstream 100 bases:

>100_bases
CTAACAGAATTGAAAAAATGTGATCTTAGGAGATCTGAGAGTTTTTCTTATAATCTAAACATTGAAATACTAAATAAGCA
ACTAGATATGGGGGGTTATC

Downstream 100 bases:

>100_bases
TGAGCATGAGTTTTGTTAGGCTTCCTTTTAGAGATAGCTATTATGAGCTAAGGCCAACCAAGATAATAGCTCTAGCAAAG
AACTATGCAGAGCATGCAAA

Product: hypothetical protein

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MVKVAYVQMEPKILELDKNLSKAEKLVKEAAKREAKLIVLPELFDTGYNFESRDEVFEIAQRIPEGETTTFLMDLAGDLE
VYIVAGTAEKYNDRLYNSAVLVGPTGYLGKYRKIHLFYREKVFFDPGDLGFNVFDLGFIRVGIMICFDWFFPESARTLAL
KGADIIAHPANLVMPYAPRAMPIRALENRVYIITADRVGEERGLRFIGKSLIASPKAEVLAMGSETEEEVGVAEVDISLV
RNKRINDLNDIFKDRRPEYYFR

Sequences:

>Translated_262_residues
MVKVAYVQMEPKILELDKNLSKAEKLVKEAAKREAKLIVLPELFDTGYNFESRDEVFEIAQRIPEGETTTFLMDLAGDLE
VYIVAGTAEKYNDRLYNSAVLVGPTGYLGKYRKIHLFYREKVFFDPGDLGFNVFDLGFIRVGIMICFDWFFPESARTLAL
KGADIIAHPANLVMPYAPRAMPIRALENRVYIITADRVGEERGLRFIGKSLIASPKAEVLAMGSETEEEVGVAEVDISLV
RNKRINDLNDIFKDRRPEYYFR
>Mature_262_residues
MVKVAYVQMEPKILELDKNLSKAEKLVKEAAKREAKLIVLPELFDTGYNFESRDEVFEIAQRIPEGETTTFLMDLAGDLE
VYIVAGTAEKYNDRLYNSAVLVGPTGYLGKYRKIHLFYREKVFFDPGDLGFNVFDLGFIRVGIMICFDWFFPESARTLAL
KGADIIAHPANLVMPYAPRAMPIRALENRVYIITADRVGEERGLRFIGKSLIASPKAEVLAMGSETEEEVGVAEVDISLV
RNKRINDLNDIFKDRRPEYYFR

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=274, Percent_Identity=31.021897810219, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI7706509, Length=267, Percent_Identity=26.2172284644195, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1786412, Length=249, Percent_Identity=24.0963855421687, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17533173, Length=281, Percent_Identity=27.0462633451957, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17557111, Length=293, Percent_Identity=26.6211604095563, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17556280, Length=277, Percent_Identity=24.9097472924188, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323383, Length=263, Percent_Identity=26.9961977186312, Blast_Score=96, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21355835, Length=281, Percent_Identity=30.2491103202847, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17933642, Length=257, Percent_Identity=29.5719844357977, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21358471, Length=252, Percent_Identity=24.2063492063492, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 29864; Mature: 29864

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVAYVQMEPKILELDKNLSKAEKLVKEAAKREAKLIVLPELFDTGYNFESRDEVFEIA
CEEEEEEEECCCCEECCCCHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCHHHHHHHH
QRIPEGETTTFLMDLAGDLEVYIVAGTAEKYNDRLYNSAVLVGPTGYLGKYRKIHLFYRE
HHCCCCCCEEEEEEECCCEEEEEEECCCHHHHHHHHCCEEEECCCCCCCCCEEEEEEEEE
KVFFDPGDLGFNVFDLGFIRVGIMICFDWFFPESARTLALKGADIIAHPANLVMPYAPRA
EEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEECCCCEEECCCCCC
MPIRALENRVYIITADRVGEERGLRFIGKSLIASPKAEVLAMGSETEEEVGVAEVDISLV
CCHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHCCCHHHHHHHH
RNKRINDLNDIFKDRRPEYYFR
HCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVKVAYVQMEPKILELDKNLSKAEKLVKEAAKREAKLIVLPELFDTGYNFESRDEVFEIA
CEEEEEEEECCCCEECCCCHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCHHHHHHHH
QRIPEGETTTFLMDLAGDLEVYIVAGTAEKYNDRLYNSAVLVGPTGYLGKYRKIHLFYRE
HHCCCCCCEEEEEEECCCEEEEEEECCCHHHHHHHHCCEEEECCCCCCCCCEEEEEEEEE
KVFFDPGDLGFNVFDLGFIRVGIMICFDWFFPESARTLALKGADIIAHPANLVMPYAPRA
EEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEECCCCEEECCCCCC
MPIRALENRVYIITADRVGEERGLRFIGKSLIASPKAEVLAMGSETEEEVGVAEVDISLV
CCHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHCCCHHHHHHHH
RNKRINDLNDIFKDRRPEYYFR
HCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8526497 [H]