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The map label for this gene is 18977370

Identifier: 18977370

GI number: 18977370

Start: 955455

End: 956522

Strand: Direct

Name: 18977370

Synonym: PF0998

Alternate gene names: NA

Gene position: 955455-956522 (Clockwise)

Preceding gene: 18977369

Following gene: 18977374

Centisome position: 50.07

GC content: 38.3

Gene sequence:

>1068_bases
GTGAAGCAGAAGAAGGCATGGGCAATAGTAAAGGAGGTCATCAATGAGGCAGATATAGTTGTTGAGGTAGTCGATGCTAG
GGATCCCATAGGAACCAGAAACAGGAAACTTGAAAGGATGGTTTTAGAGAGCGGTAAAAAGCTTCTATTGGTTATGAATA
AAGCAGACTTAGTCCCTAAAGACTGGGCTGAAGAATATAAGAGGAAAAGCGAAATTCCAGTTGTGTTTATTTCAGCTAGA
GAAAGGAAGGGAACTGGTATCTTTCGAAAGGAACTGAAGAAATTGGCTAAAGAGATAGACAAAGAGAAGGTGAAAGTCGC
TCTAATTGGATATCCAAATGTCGGGAAGAGCACGATAATAAATGTGTTAAAAGGTAAACATGCAGTTGGAACAGCTCCAA
TTCCTGGGTATACGAAGGGAAAGCAACTCATAAGATTAACTAAAAGGATATGGCTACTAGACACCCCAGGTGTTGTTCCA
ATAGATGACTTTGATGAGTTAGTTATTAAAGGAGGATTTCCGGCAGATAAAATCAGGGATCCTGTAAAGCCTGCATTAAA
GTTAATCAAGAGAATTCTTGAAACAAGAAAAGAAGCTATAACAGAGAAATTTGGAATTGAGAAGTTTGAAAACGAGGAGG
AAATTCTAGAGGAGATAGGAAAAAGAAGGGGTCTTATAAAGGCGGGTGGTGAAGTAGATATTGAAGAAACCGCAAGGTGG
TTTCTTCGTGAGTGGCAAACTGGAAGATTCACTTTATTTGGAAAAGAAGAAAAAAGAGAAGAGGAATATTTGCCAAGCTT
TCATGATATCCTTGAATACATCAAAAAAGAGAAAATTACAGAGCCCAGGATGATACTATGGAAGTTTGGAAAAAAGCTAG
AAGAGTATTTGGGAAGTGAAAAGAGGCTTGGGACAATCCAAATAGATGAATTCACTGTAGCAATAGCTACGGGATTTAAG
AAGTGTCCAAACGCATTGAAGTTTATCGAAAAAGTCACTGGAAAAACAGTAATCTCAGCAGAATGCTTTGGAAAGAAATG
GAAGGGAATAGTGGCAATTCTAGAATAA

Upstream 100 bases:

>100_bases
GGTCTCGGAAAGAATGGAAAAGCATATGTTCAATGTCTAGACCCAGGTCCCCCCTATACTGAAGGTGGAACAGTGATATT
TGAAATTGAGGTGGTCAGAA

Downstream 100 bases:

>100_bases
TCATTTGTTGGAAGAAATTAAGACAAAACTTGCACTTAAAGCTGCCATAAAAAGGCCTGGGGGAAGTATCCACCACCAAT
ACCCGCCATAGATTGCTCCC

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKQKKAWAIVKEVINEADIVVEVVDARDPIGTRNRKLERMVLESGKKLLLVMNKADLVPKDWAEEYKRKSEIPVVFISAR
ERKGTGIFRKELKKLAKEIDKEKVKVALIGYPNVGKSTIINVLKGKHAVGTAPIPGYTKGKQLIRLTKRIWLLDTPGVVP
IDDFDELVIKGGFPADKIRDPVKPALKLIKRILETRKEAITEKFGIEKFENEEEILEEIGKRRGLIKAGGEVDIEETARW
FLREWQTGRFTLFGKEEKREEEYLPSFHDILEYIKKEKITEPRMILWKFGKKLEEYLGSEKRLGTIQIDEFTVAIATGFK
KCPNALKFIEKVTGKTVISAECFGKKWKGIVAILE

Sequences:

>Translated_355_residues
MKQKKAWAIVKEVINEADIVVEVVDARDPIGTRNRKLERMVLESGKKLLLVMNKADLVPKDWAEEYKRKSEIPVVFISAR
ERKGTGIFRKELKKLAKEIDKEKVKVALIGYPNVGKSTIINVLKGKHAVGTAPIPGYTKGKQLIRLTKRIWLLDTPGVVP
IDDFDELVIKGGFPADKIRDPVKPALKLIKRILETRKEAITEKFGIEKFENEEEILEEIGKRRGLIKAGGEVDIEETARW
FLREWQTGRFTLFGKEEKREEEYLPSFHDILEYIKKEKITEPRMILWKFGKKLEEYLGSEKRLGTIQIDEFTVAIATGFK
KCPNALKFIEKVTGKTVISAECFGKKWKGIVAILE
>Mature_355_residues
MKQKKAWAIVKEVINEADIVVEVVDARDPIGTRNRKLERMVLESGKKLLLVMNKADLVPKDWAEEYKRKSEIPVVFISAR
ERKGTGIFRKELKKLAKEIDKEKVKVALIGYPNVGKSTIINVLKGKHAVGTAPIPGYTKGKQLIRLTKRIWLLDTPGVVP
IDDFDELVIKGGFPADKIRDPVKPALKLIKRILETRKEAITEKFGIEKFENEEEILEEIGKRRGLIKAGGEVDIEETARW
FLREWQTGRFTLFGKEEKREEEYLPSFHDILEYIKKEKITEPRMILWKFGKKLEEYLGSEKRLGTIQIDEFTVAIATGFK
KCPNALKFIEKVTGKTVISAECFGKKWKGIVAILE

Specific function: Unknown

COG id: COG1161

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI7019419, Length=275, Percent_Identity=36, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI296317324, Length=280, Percent_Identity=30.7142857142857, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI9506611, Length=280, Percent_Identity=30.7142857142857, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI45593130, Length=274, Percent_Identity=30.2919708029197, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI45643129, Length=274, Percent_Identity=30.2919708029197, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI45643127, Length=274, Percent_Identity=30.2919708029197, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI223029424, Length=221, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17534827, Length=320, Percent_Identity=30, Blast_Score=150, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI32563985, Length=275, Percent_Identity=33.4545454545455, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71990926, Length=275, Percent_Identity=33.4545454545455, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32563983, Length=275, Percent_Identity=33.4545454545455, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25143545, Length=280, Percent_Identity=30.3571428571429, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI115535155, Length=285, Percent_Identity=29.8245614035088, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71982363, Length=220, Percent_Identity=33.1818181818182, Blast_Score=105, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6324381, Length=262, Percent_Identity=30.5343511450382, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320842, Length=294, Percent_Identity=29.5918367346939, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6321339, Length=310, Percent_Identity=29.3548387096774, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19922460, Length=263, Percent_Identity=35.361216730038, Blast_Score=151, Evalue=8e-37,
Organism=Drosophila melanogaster, GI28572990, Length=273, Percent_Identity=30.4029304029304, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI18543229, Length=165, Percent_Identity=32.7272727272727, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023179
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR000795 [H]

Pfam domain/function: PF00009 GTP_EFTU; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 40688; Mature: 40688

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKKAWAIVKEVINEADIVVEVVDARDPIGTRNRKLERMVLESGKKLLLVMNKADLVPK
CCCHHHHHHHHHHHCCHHEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCH
DWAEEYKRKSEIPVVFISARERKGTGIFRKELKKLAKEIDKEKVKVALIGYPNVGKSTII
HHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCHHHEEEEEEECCCCCHHHHH
NVLKGKHAVGTAPIPGYTKGKQLIRLTKRIWLLDTPGVVPIDDFDELVIKGGFPADKIRD
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCCHHHHHEECCCCHHHHCC
PVKPALKLIKRILETRKEAITEKFGIEKFENEEEILEEIGKRRGLIKAGGEVDIEETARW
HHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCCCEECCCCCCHHHHHHH
FLREWQTGRFTLFGKEEKREEEYLPSFHDILEYIKKEKITEPRMILWKFGKKLEEYLGSE
HHHHCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
KRLGTIQIDEFTVAIATGFKKCPNALKFIEKVTGKTVISAECFGKKWKGIVAILE
CCCCEEEEHHEEEHHHHHHHHCHHHHHHHHHHHCCEEEEHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MKQKKAWAIVKEVINEADIVVEVVDARDPIGTRNRKLERMVLESGKKLLLVMNKADLVPK
CCCHHHHHHHHHHHCCHHEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCH
DWAEEYKRKSEIPVVFISARERKGTGIFRKELKKLAKEIDKEKVKVALIGYPNVGKSTII
HHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCHHHEEEEEEECCCCCHHHHH
NVLKGKHAVGTAPIPGYTKGKQLIRLTKRIWLLDTPGVVPIDDFDELVIKGGFPADKIRD
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCCHHHHHEECCCCHHHHCC
PVKPALKLIKRILETRKEAITEKFGIEKFENEEEILEEIGKRRGLIKAGGEVDIEETARW
HHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCCCEECCCCCCHHHHHHH
FLREWQTGRFTLFGKEEKREEEYLPSFHDILEYIKKEKITEPRMILWKFGKKLEEYLGSE
HHHHCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
KRLGTIQIDEFTVAIATGFKKCPNALKFIEKVTGKTVISAECFGKKWKGIVAILE
CCCCEEEEHHEEEHHHHHHHHCHHHHHHHHHHHCCEEEEHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]