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The map label for this gene is porA

Identifier: 18977338

GI number: 18977338

Start: 926380

End: 927570

Strand: Reverse

Name: porA

Synonym: PF0966

Alternate gene names: 18977338

Gene position: 927570-926380 (Counterclockwise)

Preceding gene: 18977339

Following gene: 18977337

Centisome position: 48.61

GC content: 44.25

Gene sequence:

>1191_bases
ATGCCAATTAGGAAAGTTATGAAGGCTAATGAAGCCGCTGCTTGGGCTGCTAAGTTGGCTAAACCAAAGGTTATAGCAGC
ATTCCCAATTACACCTTCAACCCTAATACCCGAGAAGATTAGTGAATTCGTGGCAAATGGTGAACTAGACGCAGAGTTTA
TTAAAGTTGAAAGTGAGCACTCAGCAATTTCAGCATGTGTAGGTGCGGCTGCTGCAGGTGTTAGAACCTTCACAGCAACA
GCCTCTCAAGGTTTGGCTTTAATGCACGAAATTCTATTCATTGCTGCTGGCATGAGATTGCCAATTGTAATGGCAATTGG
TAACAGAGCTTTGTCAGCTCCAATTAACATCTGGAATGACTGGCAAGACACAATTAGCCAAAGAGATACTGGATGGATGC
AGTTCTATGCAGAAAACAACCAAGAGGCTCTAGACTTGATCCTAATAGCTTACAAAGTTGCAGAAGATGAAAGAGTCCTC
CTTCCAGCCATGGTTGGATTCGATGCATTCATCCTAACCCATACAGTTGAACCAGTAGAAATCCCAGACCAAGAGGTTGT
TGATGAATTCCTAGGAGAATACGAGCCCAAGCACGCATATATTGATCCCGCAAGGCCTATAACTCAAGGAAGCCTTGCAT
TCCCGGCCCACTATATGGAGAGCAGATACACAGTTTGGGAGGCTATGGAGAGAGCAAAGAAGGTAATAGACGAAGCATTT
GCAGAATTCGAGAAGAAGTTCGGAAGAAAGTACCAGAAGATTGAGGAGTACAAGACAGAGGATGCAGACATAATCTTCGT
AACAATGGGTTCACTGGCTGGAACCCTTAAAGAGTGGATAGACAAGAAGAGAGAGGAAGGTTACAAAGTCGGTGCAGCAA
AGATAACCGTTTATAGGCCATTCCCAGTAGAAGAGATAAGAGAACTAGCAAAGAAGGCAAAGGTTCTCGCATTCCTAGAG
AAGAACATCACAATCGGCCTTTATGGTGCAGTCTTTACGGATGCATCAGCAGCTCTCATCAACGAGAGCGAAAAGCCACT
AATGGTCGACTTCATAGTTGGCCTAGGTGGAAGAGATGTAACCTTCAACCAGCTTGACGAAGCCCTGGAAATTGCAGAGA
AGGCACTCAAGGAAGGTAAAGTTGAGAATCCAATTAACTGGATTGGATTAAGATGGGAACTTGTGAAGTGA

Upstream 100 bases:

>100_bases
GTTTTTGACTACGACTATTGTAAGGGTTGTGGAATCTGTGCTAATGAGTGTCCAACAAAAGCCATTGAAATGGTTAGAGA
AGTTAAGTGAGGTGGTTTAG

Downstream 100 bases:

>100_bases
GGTGATTGAGATGGCAGTTAGAAAGCCCCCAATAACTACCCGTGAATATTGGGCTCCTGGTCATGCCGCATGTGCAGGTT
GTGGGTGTGCTACTGCTCTA

Product: pyruvate ferredoxin oxidoreductase subunit alpha

Products: NA

Alternate protein names: Pyruvate oxidoreductase alpha chain; POR; Pyruvic-ferredoxin oxidoreductase subunit alpha

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MPIRKVMKANEAAAWAAKLAKPKVIAAFPITPSTLIPEKISEFVANGELDAEFIKVESEHSAISACVGAAAAGVRTFTAT
ASQGLALMHEILFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTISQRDTGWMQFYAENNQEALDLILIAYKVAEDERVL
LPAMVGFDAFILTHTVEPVEIPDQEVVDEFLGEYEPKHAYIDPARPITQGSLAFPAHYMESRYTVWEAMERAKKVIDEAF
AEFEKKFGRKYQKIEEYKTEDADIIFVTMGSLAGTLKEWIDKKREEGYKVGAAKITVYRPFPVEEIRELAKKAKVLAFLE
KNITIGLYGAVFTDASAALINESEKPLMVDFIVGLGGRDVTFNQLDEALEIAEKALKEGKVENPINWIGLRWELVK

Sequences:

>Translated_396_residues
MPIRKVMKANEAAAWAAKLAKPKVIAAFPITPSTLIPEKISEFVANGELDAEFIKVESEHSAISACVGAAAAGVRTFTAT
ASQGLALMHEILFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTISQRDTGWMQFYAENNQEALDLILIAYKVAEDERVL
LPAMVGFDAFILTHTVEPVEIPDQEVVDEFLGEYEPKHAYIDPARPITQGSLAFPAHYMESRYTVWEAMERAKKVIDEAF
AEFEKKFGRKYQKIEEYKTEDADIIFVTMGSLAGTLKEWIDKKREEGYKVGAAKITVYRPFPVEEIRELAKKAKVLAFLE
KNITIGLYGAVFTDASAALINESEKPLMVDFIVGLGGRDVTFNQLDEALEIAEKALKEGKVENPINWIGLRWELVK
>Mature_395_residues
PIRKVMKANEAAAWAAKLAKPKVIAAFPITPSTLIPEKISEFVANGELDAEFIKVESEHSAISACVGAAAAGVRTFTATA
SQGLALMHEILFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTISQRDTGWMQFYAENNQEALDLILIAYKVAEDERVLL
PAMVGFDAFILTHTVEPVEIPDQEVVDEFLGEYEPKHAYIDPARPITQGSLAFPAHYMESRYTVWEAMERAKKVIDEAFA
EFEKKFGRKYQKIEEYKTEDADIIFVTMGSLAGTLKEWIDKKREEGYKVGAAKITVYRPFPVEEIRELAKKAKVLAFLEK
NITIGLYGAVFTDASAALINESEKPLMVDFIVGLGGRDVTFNQLDEALEIAEKALKEGKVENPINWIGLRWELVK

Specific function: Oxidoreductase Required For The Transfer Of Electrons From Pyruvate To Flavodoxin (Potential). [C]

COG id: COG0674

COG function: function code C; Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787642, Length=352, Percent_Identity=29.8295454545455, Blast_Score=135, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PORA_PYRFU (Q51804)

Other databases:

- EMBL:   X85250
- EMBL:   AE009950
- PIR:   T45088
- RefSeq:   NP_578695.1
- ProteinModelPortal:   Q51804
- EnsemblBacteria:   EBPYRT00000005763
- GeneID:   1468831
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF0966
- NMPDR:   fig|186497.1.peg.1002
- GeneTree:   EBGT00050000022252
- HOGENOM:   HBG313202
- OMA:   ESEHAAM
- ProtClustDB:   PRK08367
- BRENDA:   1.2.7.1
- InterPro:   IPR002880
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005476
- Gene3D:   G3DSA:3.40.50.920

Pfam domain/function: PF01855 POR_N; PF02780 Transketolase_C; SSF52922 Transketo_C_like

EC number: =1.2.7.1

Molecular weight: Translated: 44177; Mature: 44046

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRKVMKANEAAAWAAKLAKPKVIAAFPITPSTLIPEKISEFVANGELDAEFIKVESEH
CCHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCHHHEEEECHH
SAISACVGAAAAGVRTFTATASQGLALMHEILFIAAGMRLPIVMAIGNRALSAPINIWND
HHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHCCCCCCCCC
WQDTISQRDTGWMQFYAENNQEALDLILIAYKVAEDERVLLPAMVGFDAFILTHTVEPVE
HHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCC
IPDQEVVDEFLGEYEPKHAYIDPARPITQGSLAFPAHYMESRYTVWEAMERAKKVIDEAF
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AEFEKKFGRKYQKIEEYKTEDADIIFVTMGSLAGTLKEWIDKKREEGYKVGAAKITVYRP
HHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEECEEEEEEECC
FPVEEIRELAKKAKVLAFLEKNITIGLYGAVFTDASAALINESEKPLMVDFIVGLGGRDV
CCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCHHHHHCCCCCCEEEEEEECCCCCCC
TFNQLDEALEIAEKALKEGKVENPINWIGLRWELVK
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure 
PIRKVMKANEAAAWAAKLAKPKVIAAFPITPSTLIPEKISEFVANGELDAEFIKVESEH
CHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCHHHEEEECHH
SAISACVGAAAAGVRTFTATASQGLALMHEILFIAAGMRLPIVMAIGNRALSAPINIWND
HHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHCCCCCCCCC
WQDTISQRDTGWMQFYAENNQEALDLILIAYKVAEDERVLLPAMVGFDAFILTHTVEPVE
HHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCC
IPDQEVVDEFLGEYEPKHAYIDPARPITQGSLAFPAHYMESRYTVWEAMERAKKVIDEAF
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AEFEKKFGRKYQKIEEYKTEDADIIFVTMGSLAGTLKEWIDKKREEGYKVGAAKITVYRP
HHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEECEEEEEEECC
FPVEEIRELAKKAKVLAFLEKNITIGLYGAVFTDASAALINESEKPLMVDFIVGLGGRDV
CCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCHHHHHCCCCCCEEEEEEECCCCCCC
TFNQLDEALEIAEKALKEGKVENPINWIGLRWELVK
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550425; 8305426; 8380721