Click here to switch to the map view.

The map label for this gene is fni

Identifier: 18977228

GI number: 18977228

Start: 830358

End: 831542

Strand: Direct

Name: fni

Synonym: PF0856

Alternate gene names: 18977228

Gene position: 830358-831542 (Clockwise)

Preceding gene: 18977223

Following gene: 33359517

Centisome position: 43.51

GC content: 43.63

Gene sequence:

>1185_bases
ATGGATGAAGGGACTCGCACTGTTCTTAGAAAGTTTGAGCACATAGAGCACTGCCTCAAGAGAAATGTTGAGGCCCACGC
AACTAATGGCTTTGAAGATGTTCACTTCGTCCATATGAGCCTTCCAGAGATTGATAAGGATGAGATTGATCTTTCAGTAA
AATTCCTAGGAAGGAAGTTTGATTATCCAATAATGATTACTGGGATGACTGGTGGAACAAGAAAAGGAGAAGTAGCGTGG
AAAATCAACAGAACACTTGCCCAAGCGGCTGAAGAGCTAAATATTCCTCTTGGGGTGGGAAGTCAAAGGGCCATGATAGA
GAAGCCAGAAACTTGGGAAAGTTATTATGTGAGAGATGTGGCCCCGAATGTCTTCTTAGTTGGAAATTTAGGGGCACCTC
AGTTTGGGAGGAATGCAAAGAGGAAGTATGGGGTGAAGGAAGTTCTTTATGCAATAGAAAAGATAGATGCGGATGCCATA
GCAATCCACATGAATCCACTTCAGGAGAGCGTTCAGCCAGAGGGGGATACGACATTTTCAGGCGTTCTTGAAGCTTTGGC
CGAGATAACTTCTTCAATAGATTATCCTGTAATAGCGAAGGAGACAGGAGCTGGAGTTTCGAAGGAGGTTGCAATAAAGC
TGGAGAGCATTGGAGTTAGTGCAATAGATATTAGCGGTGTTGGGGGGACAAGCTGGAGTGGAGTGGAATATTATAGGGCC
AAAGATGAGTTGGGAAAGAGGTTGGCTCTAAGATTTTGGGATTGGGGGATAAAAACGGCCATAAGCTTAGCTGAAGTTAG
GTTTTCAACTAACCTCCCAATAATAGCCAGTGGTGGTATGAGGGATGGAATTACAATGGCAAAAGCTCTAGCCATGGGAG
CTTCTCTTGTTGGAATAGCGTTACCTGTTCTGAAACCTGCCGCAAAAGGGGATGTAGAAGGGGTGATCAAAGTCATCAAA
GGATACGTTGAAGAAATCAAGAACGCAATGTTTCTCGTTGGAGCTAGAAATGTAGAAGAGCTGAGAAAAGTCCCGATAGT
ATTTACCGGATTTGTCAGAGAGTGGTTGGAGCAGAGGATAGATCTGCAAGAGTTTGTAAAAAAGAGGGCAAAGTTAAGAT
TTGAATTTTGGAACGTAGGCTTTTATTCCTATCCTTACACATCCTCCTCCACACACCTCTTTTAA

Upstream 100 bases:

>100_bases
GGCCGGTAGCTCAGCCTGGAAGAGCGCCGCCCTCGCAAGGCGGAGGCCGCGGGTTCAAATCCCGCCCGGTCCACCAAATT
CTTCTTAGGGAGGGAATCAA

Downstream 100 bases:

>100_bases
TGGACAATTGTTGCAGCTCTCTGCCTCTACTTCCTCAATGTAATCTAAGGCCTTTAAGATTTCTAACATCCCTTTTACCT
CCTCTCTCGAAACTCTAAGT

Product: isopentenyl pyrophosphate isomerase

Products: NA

Alternate protein names: IPP isomerase; Isopentenyl pyrophosphate isomerase

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MDEGTRTVLRKFEHIEHCLKRNVEAHATNGFEDVHFVHMSLPEIDKDEIDLSVKFLGRKFDYPIMITGMTGGTRKGEVAW
KINRTLAQAAEELNIPLGVGSQRAMIEKPETWESYYVRDVAPNVFLVGNLGAPQFGRNAKRKYGVKEVLYAIEKIDADAI
AIHMNPLQESVQPEGDTTFSGVLEALAEITSSIDYPVIAKETGAGVSKEVAIKLESIGVSAIDISGVGGTSWSGVEYYRA
KDELGKRLALRFWDWGIKTAISLAEVRFSTNLPIIASGGMRDGITMAKALAMGASLVGIALPVLKPAAKGDVEGVIKVIK
GYVEEIKNAMFLVGARNVEELRKVPIVFTGFVREWLEQRIDLQEFVKKRAKLRFEFWNVGFYSYPYTSSSTHLF

Sequences:

>Translated_394_residues
MDEGTRTVLRKFEHIEHCLKRNVEAHATNGFEDVHFVHMSLPEIDKDEIDLSVKFLGRKFDYPIMITGMTGGTRKGEVAW
KINRTLAQAAEELNIPLGVGSQRAMIEKPETWESYYVRDVAPNVFLVGNLGAPQFGRNAKRKYGVKEVLYAIEKIDADAI
AIHMNPLQESVQPEGDTTFSGVLEALAEITSSIDYPVIAKETGAGVSKEVAIKLESIGVSAIDISGVGGTSWSGVEYYRA
KDELGKRLALRFWDWGIKTAISLAEVRFSTNLPIIASGGMRDGITMAKALAMGASLVGIALPVLKPAAKGDVEGVIKVIK
GYVEEIKNAMFLVGARNVEELRKVPIVFTGFVREWLEQRIDLQEFVKKRAKLRFEFWNVGFYSYPYTSSSTHLF
>Mature_394_residues
MDEGTRTVLRKFEHIEHCLKRNVEAHATNGFEDVHFVHMSLPEIDKDEIDLSVKFLGRKFDYPIMITGMTGGTRKGEVAW
KINRTLAQAAEELNIPLGVGSQRAMIEKPETWESYYVRDVAPNVFLVGNLGAPQFGRNAKRKYGVKEVLYAIEKIDADAI
AIHMNPLQESVQPEGDTTFSGVLEALAEITSSIDYPVIAKETGAGVSKEVAIKLESIGVSAIDISGVGGTSWSGVEYYRA
KDELGKRLALRFWDWGIKTAISLAEVRFSTNLPIIASGGMRDGITMAKALAMGASLVGIALPVLKPAAKGDVEGVIKVIK
GYVEEIKNAMFLVGARNVEELRKVPIVFTGFVREWLEQRIDLQEFVKKRAKLRFEFWNVGFYSYPYTSSSTHLF

Specific function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IPP isomerase type 2 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IDI2_PYRFU (Q8U2H9)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_578585.1
- ProteinModelPortal:   Q8U2H9
- SMR:   Q8U2H9
- EnsemblBacteria:   EBPYRT00000005897
- GeneID:   1468714
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF0856
- NMPDR:   fig|186497.1.peg.885
- GeneTree:   EBGT00050000022727
- HOGENOM:   HBG354479
- OMA:   GSQRAAI
- ProtClustDB:   PRK05437
- BRENDA:   5.3.3.2
- GO:   GO:0005737
- HAMAP:   MF_00354
- InterPro:   IPR013785
- InterPro:   IPR000262
- InterPro:   IPR011179
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10578:SF3
- PIRSF:   PIRSF003314
- TIGRFAMs:   TIGR02151

Pfam domain/function: PF01070 FMN_dh

EC number: =5.3.3.2

Molecular weight: Translated: 43726; Mature: 43726

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEGTRTVLRKFEHIEHCLKRNVEAHATNGFEDVHFVHMSLPEIDKDEIDLSVKFLGRKF
CCCHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEEEEECCCCCCCHHHCEEEEEECCCC
DYPIMITGMTGGTRKGEVAWKINRTLAQAAEELNIPLGVGSQRAMIEKPETWESYYVRDV
CCCEEEEECCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCC
APNVFLVGNLGAPQFGRNAKRKYGVKEVLYAIEKIDADAIAIHMNPLQESVQPEGDTTFS
CCCEEEEECCCCCCCCCCCHHHCCHHHHHHHHHHCCCCEEEEEECHHHHHCCCCCCCHHH
GVLEALAEITSSIDYPVIAKETGAGVSKEVAIKLESIGVSAIDISGVGGTSWSGVEYYRA
HHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCHHHHH
KDELGKRLALRFWDWGIKTAISLAEVRFSTNLPIIASGGMRDGITMAKALAMGASLVGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
LPVLKPAAKGDVEGVIKVIKGYVEEIKNAMFLVGARNVEELRKVPIVFTGFVREWLEQRI
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHCCCCHHHHHHHHHHHHCC
DLQEFVKKRAKLRFEFWNVGFYSYPYTSSSTHLF
CHHHHHHHHHCEEEEEEECCEEECCCCCCCCCCC
>Mature Secondary Structure
MDEGTRTVLRKFEHIEHCLKRNVEAHATNGFEDVHFVHMSLPEIDKDEIDLSVKFLGRKF
CCCHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEEEEECCCCCCCHHHCEEEEEECCCC
DYPIMITGMTGGTRKGEVAWKINRTLAQAAEELNIPLGVGSQRAMIEKPETWESYYVRDV
CCCEEEEECCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCC
APNVFLVGNLGAPQFGRNAKRKYGVKEVLYAIEKIDADAIAIHMNPLQESVQPEGDTTFS
CCCEEEEECCCCCCCCCCCHHHCCHHHHHHHHHHCCCCEEEEEECHHHHHCCCCCCCHHH
GVLEALAEITSSIDYPVIAKETGAGVSKEVAIKLESIGVSAIDISGVGGTSWSGVEYYRA
HHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCHHHHH
KDELGKRLALRFWDWGIKTAISLAEVRFSTNLPIIASGGMRDGITMAKALAMGASLVGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
LPVLKPAAKGDVEGVIKVIKGYVEEIKNAMFLVGARNVEELRKVPIVFTGFVREWLEQRI
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHCCCCHHHHHHHHHHHHCC
DLQEFVKKRAKLRFEFWNVGFYSYPYTSSSTHLF
CHHHHHHHHHCEEEEEEECCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA