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The map label for this gene is ypnP [H]

Identifier: 18977195

GI number: 18977195

Start: 800694

End: 802109

Strand: Direct

Name: ypnP [H]

Synonym: PF0823

Alternate gene names: 18977195

Gene position: 800694-802109 (Clockwise)

Preceding gene: 18977194

Following gene: 18977196

Centisome position: 41.96

GC content: 43.36

Gene sequence:

>1416_bases
ATGAGCAGAGAAAAAATAGAGGCCAACAGGGAGAAGATACTCAACGGTCCCATTGTCCCTACTCTCTTAGTGTTAGCTTA
TCCTATAATAATTAATCAACTCGTTCACGTTCTCTACAATTTAACCGACACTTTTTGGCTTGGTAAATTGGGGAGAATTG
AGCTTTCAGCCCCTGGGACGGCCTGGCCCCTAGTTTGGTTTCTCATGAGCATAGGTAGTGGATTCGTGGTTGCCGGCTTC
GCCTTTGTGAGTCAATACATTGGGGCAGGAGATTATGAGAAGGCCAACCGCTATGCTGGAGCTCTGTATTCGCTCCTCTT
AATTTTTGCCACTGGGATGAGTATATTTGGAATAGTATTAGCTCCCTACTTTTTGAGATTCATGAAGGTTAGCGAAACTA
TATTTCCCTATGCCCTAACATACACAAGAATAATCTTTGCAGGAATACCTTTCTCATTTACGCTCTTCGCGTTTAACTTT
CTCCTGAGAGCTATTGGAGATACGAAAACTCCCGTTAAGATCAACATAGGTACAATCATCCTAAACATTATCTTAGATCC
ATTCTTTATCTTTGGCTGGGGACCATTTCCCAGGTTGGGAGTTGCTGGAGCGGCCATTGCAACGATGCTCTCGAACAGCG
TTGGCTCCTTGATTGGGGGTTACCTCCTCTTTACTGGAAAAGTTGGGATACACTTAACCCTGGAGAACTTAAAGCCTGAT
CTAAAATTCTACTCTAGAATATTTAGGGTTGGCTTGCCTTCAAGCATTGGAGACTCAACCTCCGCCCTTGGATTCGTAGT
ACTCACTAGAGTAATATTTACGGTTGGAAGAATTTATGGTGAAGCCCATGGGATTAAGGGGTATGAGGACGTTGCCTTTC
CCACCTATAGCATAACTAACAGGTTAACGAACTTCATGTTTGCCTTTTCAGATGGAATTAGCATGGCAATGGGTACTATG
GTTGGGCAAAATATTGGGGCCAGAAAGTACGAGAGGGCTAAGGAAATAGCTGAAAAAGCCATGCTCATAAACTTCACGAT
ATTGAGCATTGGAACGCTTTTGTTTGCAATATTTAGGGTTCCAATTTTCAAGTTCTTCGTCAATGATCCCATGGTAATAG
CTGAGAGCAAAAAAGTTGTCATGTACTTCTCAGCTTCCTTACCCTTCTTCGGTATATTCTCTGCTGTAAATCAGGTTTTT
AATAGTGCGGGACACACGAAGAAGAGCATGGTACTTGGAATAATAAGGCTGTGGATCCTCAGAATTCCGTTGAGCTATTG
GCTGGGAGTTGCCATGAAAGACACTGCAGGAATGTGGCTTGGAATGGGATTAAGTAACGTTATAGGAGCTCTTATAGGCT
TGGCTTGGTTCCTCAAGGGAAGCTGGTTAAGGGGTGTTATTGAGGAGCACCACTGA

Upstream 100 bases:

>100_bases
CGCCGTTAAAGATCTATTGTCTGAGCTAAGGAAGAGGAAGTAGTGGGCTTTTTTATCCATAATAAATTTTTTAAAACGCT
TAGATTCCTATCTAATCGAG

Downstream 100 bases:

>100_bases
CGTGGTAAAAATGGAGCGCGGAAAGATTCAAGCGATGCGAGAGCAAATCCTTAATGGTCCAATAGAAAAGACTCTCATCA
AGTTAGCGTATCCTTTAATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSREKIEANREKILNGPIVPTLLVLAYPIIINQLVHVLYNLTDTFWLGKLGRIELSAPGTAWPLVWFLMSIGSGFVVAGF
AFVSQYIGAGDYEKANRYAGALYSLLLIFATGMSIFGIVLAPYFLRFMKVSETIFPYALTYTRIIFAGIPFSFTLFAFNF
LLRAIGDTKTPVKINIGTIILNIILDPFFIFGWGPFPRLGVAGAAIATMLSNSVGSLIGGYLLFTGKVGIHLTLENLKPD
LKFYSRIFRVGLPSSIGDSTSALGFVVLTRVIFTVGRIYGEAHGIKGYEDVAFPTYSITNRLTNFMFAFSDGISMAMGTM
VGQNIGARKYERAKEIAEKAMLINFTILSIGTLLFAIFRVPIFKFFVNDPMVIAESKKVVMYFSASLPFFGIFSAVNQVF
NSAGHTKKSMVLGIIRLWILRIPLSYWLGVAMKDTAGMWLGMGLSNVIGALIGLAWFLKGSWLRGVIEEHH

Sequences:

>Translated_471_residues
MSREKIEANREKILNGPIVPTLLVLAYPIIINQLVHVLYNLTDTFWLGKLGRIELSAPGTAWPLVWFLMSIGSGFVVAGF
AFVSQYIGAGDYEKANRYAGALYSLLLIFATGMSIFGIVLAPYFLRFMKVSETIFPYALTYTRIIFAGIPFSFTLFAFNF
LLRAIGDTKTPVKINIGTIILNIILDPFFIFGWGPFPRLGVAGAAIATMLSNSVGSLIGGYLLFTGKVGIHLTLENLKPD
LKFYSRIFRVGLPSSIGDSTSALGFVVLTRVIFTVGRIYGEAHGIKGYEDVAFPTYSITNRLTNFMFAFSDGISMAMGTM
VGQNIGARKYERAKEIAEKAMLINFTILSIGTLLFAIFRVPIFKFFVNDPMVIAESKKVVMYFSASLPFFGIFSAVNQVF
NSAGHTKKSMVLGIIRLWILRIPLSYWLGVAMKDTAGMWLGMGLSNVIGALIGLAWFLKGSWLRGVIEEHH
>Mature_470_residues
SREKIEANREKILNGPIVPTLLVLAYPIIINQLVHVLYNLTDTFWLGKLGRIELSAPGTAWPLVWFLMSIGSGFVVAGFA
FVSQYIGAGDYEKANRYAGALYSLLLIFATGMSIFGIVLAPYFLRFMKVSETIFPYALTYTRIIFAGIPFSFTLFAFNFL
LRAIGDTKTPVKINIGTIILNIILDPFFIFGWGPFPRLGVAGAAIATMLSNSVGSLIGGYLLFTGKVGIHLTLENLKPDL
KFYSRIFRVGLPSSIGDSTSALGFVVLTRVIFTVGRIYGEAHGIKGYEDVAFPTYSITNRLTNFMFAFSDGISMAMGTMV
GQNIGARKYERAKEIAEKAMLINFTILSIGTLLFAIFRVPIFKFFVNDPMVIAESKKVVMYFSASLPFFGIFSAVNQVFN
SAGHTKKSMVLGIIRLWILRIPLSYWLGVAMKDTAGMWLGMGLSNVIGALIGLAWFLKGSWLRGVIEEHH

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=461, Percent_Identity=22.1258134490239, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 52034; Mature: 51903

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SREKIEANREKILNGPIVPTLLVLAYPIIINQLVHVLYNLTDTFWLGKLGRIELSAPGT
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC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HHHHHHHHCCHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]