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The map label for this gene is lig [H]

Identifier: 18976968

GI number: 18976968

Start: 617011

End: 617955

Strand: Reverse

Name: lig [H]

Synonym: PF0596

Alternate gene names: 18976968

Gene position: 617955-617011 (Counterclockwise)

Preceding gene: 18976970

Following gene: 18976967

Centisome position: 32.38

GC content: 42.96

Gene sequence:

>945_bases
GTGGAAGTCTCTTCTCCAGGAGATGATTTCGTCCTTAATCTTCATGGCCTCCTCAAGGGGGTTGAACATTTGGACCACCG
AAGGATATATTACCTGGTCGGAGATATTAGGATTTCGATGAAGTTCGATGTGGTAGGATTTGACTGGAAAGGTAAAGTTG
CCTTTCAGAGTCACGCTCACACAGATCACTTTGCAAGCGGGAAGATTGTATACGCCACAAAACCTACAATATTCTTGAGT
CATTTGAGGAACTCCACTCTATATTCCCAGGTCGAATATGGAAAGAGGTTCTACATCGGAGATTACAAGGCAAAACTCTA
TCCTTCTGGCCACATGCTCGGCTCCGCTGGAATTAAAATTTGGTTGGATGAGGGAACCCTCTACTATACTGGAGATATAA
AGCTTGAGAGGTTAAGAACTGCTGAGAGAGCAAAGATCCCAAAAGCTGACTTTTTAATAATAGAAGCGACTTTTGGTGTC
CCCATGTATTCCTTCCCAGAACCAAGGAAAGTAGAGAAAGAGATTATATGGTATGTGGAGGATCAACTTGACAGAGGGAA
GATACCCATCATCCAGGCAAATCCATATGGAAAAGCCCAGGAAATAATTGCCATCCTTAACGCCCATGGATACACTCCCA
GAGTTGATAGGGAAATTTTGAAAGTTTCGAGGGTCTACTCAAAATTTGGGATCGGGCTTAGAACTGATAATGAAGGAGAA
GTTATAGTGTCATCATCCAAAGGCATTCTTGTTTCTGGTTTTGGAAAAGTAAAGCTAAGCAATCACGCCGACTTTTGGGA
GCTAATTAGGATAGTTGAGAAGGTCGACCCAGAGAAAGTGTTCACAATCTTTGGCCACGCGCAGTCATTTGCGAAGATAT
TAAATGGGTTTGGGTATGAGAGCAGGTCGATATCGAGGGGAGAAGAAATTAGGAGGTGGATTTAA

Upstream 100 bases:

>100_bases
TTCCCGTTCCTACTCTCTTTATCTTATACCCCCACTCTTTTAGGTGTTCCTCAACTATTCTGGAAGTTCTCTCCTCTTCG
TAACCTAGTTCTGGGTACAT

Downstream 100 bases:

>100_bases
TGCCCCTATACTTTATTGGACTTGGGTTATATGATGAGAAAGACATAACGCTCAAAGGATTGGAGATTGCAAAAAGGTGC
GATAAGGTGTATGCAGAATT

Product: mRNA 3'-end processing factor

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MEVSSPGDDFVLNLHGLLKGVEHLDHRRIYYLVGDIRISMKFDVVGFDWKGKVAFQSHAHTDHFASGKIVYATKPTIFLS
HLRNSTLYSQVEYGKRFYIGDYKAKLYPSGHMLGSAGIKIWLDEGTLYYTGDIKLERLRTAERAKIPKADFLIIEATFGV
PMYSFPEPRKVEKEIIWYVEDQLDRGKIPIIQANPYGKAQEIIAILNAHGYTPRVDREILKVSRVYSKFGIGLRTDNEGE
VIVSSSKGILVSGFGKVKLSNHADFWELIRIVEKVDPEKVFTIFGHAQSFAKILNGFGYESRSISRGEEIRRWI

Sequences:

>Translated_314_residues
MEVSSPGDDFVLNLHGLLKGVEHLDHRRIYYLVGDIRISMKFDVVGFDWKGKVAFQSHAHTDHFASGKIVYATKPTIFLS
HLRNSTLYSQVEYGKRFYIGDYKAKLYPSGHMLGSAGIKIWLDEGTLYYTGDIKLERLRTAERAKIPKADFLIIEATFGV
PMYSFPEPRKVEKEIIWYVEDQLDRGKIPIIQANPYGKAQEIIAILNAHGYTPRVDREILKVSRVYSKFGIGLRTDNEGE
VIVSSSKGILVSGFGKVKLSNHADFWELIRIVEKVDPEKVFTIFGHAQSFAKILNGFGYESRSISRGEEIRRWI
>Mature_314_residues
MEVSSPGDDFVLNLHGLLKGVEHLDHRRIYYLVGDIRISMKFDVVGFDWKGKVAFQSHAHTDHFASGKIVYATKPTIFLS
HLRNSTLYSQVEYGKRFYIGDYKAKLYPSGHMLGSAGIKIWLDEGTLYYTGDIKLERLRTAERAKIPKADFLIIEATFGV
PMYSFPEPRKVEKEIIWYVEDQLDRGKIPIIQANPYGKAQEIIAILNAHGYTPRVDREILKVSRVYSKFGIGLRTDNEGE
VIVSSSKGILVSGFGKVKLSNHADFWELIRIVEKVDPEKVFTIFGHAQSFAKILNGFGYESRSISRGEEIRRWI

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 35810; Mature: 35810

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS00053 RIBOSOMAL_S8

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVSSPGDDFVLNLHGLLKGVEHLDHRRIYYLVGDIRISMKFDVVGFDWKGKVAFQSHAH
CCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEEEEEEEEEEEEEECCCCCEEEECCCC
TDHFASGKIVYATKPTIFLSHLRNSTLYSQVEYGKRFYIGDYKAKLYPSGHMLGSAGIKI
CCCCCCCEEEEEECCCEEEEHHCCCHHHHHHHCCCEEEEECEEEEEECCCCEEECCCEEE
WLDEGTLYYTGDIKLERLRTAERAKIPKADFLIIEATFGVPMYSFPEPRKVEKEIIWYVE
EEECCEEEEECCEEEEHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCHHEEEEEE
DQLDRGKIPIIQANPYGKAQEIIAILNAHGYTPRVDREILKVSRVYSKFGIGLRTDNEGE
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCC
VIVSSSKGILVSGFGKVKLSNHADFWELIRIVEKVDPEKVFTIFGHAQSFAKILNGFGYE
EEEECCCCEEEECCCEEEECCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCC
SRSISRGEEIRRWI
CCCCCCCHHHHHCC
>Mature Secondary Structure
MEVSSPGDDFVLNLHGLLKGVEHLDHRRIYYLVGDIRISMKFDVVGFDWKGKVAFQSHAH
CCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEEEEEEEEEEEEEECCCCCEEEECCCC
TDHFASGKIVYATKPTIFLSHLRNSTLYSQVEYGKRFYIGDYKAKLYPSGHMLGSAGIKI
CCCCCCCEEEEEECCCEEEEHHCCCHHHHHHHCCCEEEEECEEEEEECCCCEEECCCEEE
WLDEGTLYYTGDIKLERLRTAERAKIPKADFLIIEATFGVPMYSFPEPRKVEKEIIWYVE
EEECCEEEEECCEEEEHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCHHEEEEEE
DQLDRGKIPIIQANPYGKAQEIIAILNAHGYTPRVDREILKVSRVYSKFGIGLRTDNEGE
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCC
VIVSSSKGILVSGFGKVKLSNHADFWELIRIVEKVDPEKVFTIFGHAQSFAKILNGFGYE
EEEECCCCEEEECCCEEEECCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCC
SRSISRGEEIRRWI
CCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA