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The map label for this gene is gcp [H]

Identifier: 18976845

GI number: 18976845

Start: 487387

End: 488067

Strand: Direct

Name: gcp [H]

Synonym: PF0473

Alternate gene names: 18976845

Gene position: 487387-488067 (Clockwise)

Preceding gene: 18976840

Following gene: 18976849

Centisome position: 25.54

GC content: 41.12

Gene sequence:

>681_bases
GTGAGAGGGGAGTTAAAGATGAAGCTCATAAAGCAGGGGGCTGAAGCAAAGATATATCTTGCAGACTTTTCCGAATTATA
CTATGATCTTCCCATCAAGGTGATCGTTAAGGAAAGGGTCTCGAAAAGATATAGGATTCCTGAAATCGACATAAAACTCA
GAAAAGAGAGAACAATAAGAGAAGCTAGAATACTCCATAGAGCTAAGAAAGCTGGTGTAAATGTTCCCTACGTGTTTGAA
GTTGATACCAAGAACATGATAATAGTTATGGAGTTCATAGAGGGGGAGAGGCTCAAGGAGCTTTTGGAAAAACTTCCCAT
AGAAGAAAGGTTGGAGATATGTAAGGAAATTGGCAGGGTCATAGGAAAGTTACATGAGGCAGGTATTGTCCATGGGGATT
TGACGACCTCCAATATGATAATGAGAGATGGAAAAATTTACCTCATAGACTTCGGGTTAGCTGAGTTTGACGATACTTTA
GAAGCCCAGGGTGTTGATCTTCACTTGCTGAGGAGAGCAATGGAGAGTACTCACTACAGCTGGGTTGAAGAGGGATTTAA
AGCTGTTCTAAGAGGATATGAAGAGGTAAGGGGGAAAGAGAAGAGGCGTGAGATTGAGGAAAAAATCAAGGAAATTGAAT
TGAGAGGGAGATATAGGGAGAGAAGCTGGATTACTTCCTAA

Upstream 100 bases:

>100_bases
GCAGCCAGCATGAGGAGATATTCAATGGCAGTTTGAGCTCTTTTCATGGGGCCCTCATTAAAAGTTGTTCACAAAATAAT
TTAAGGCTTTTGCTGTTTAA

Downstream 100 bases:

>100_bases
ATTTTTTAAGTATTCTGTTCATTATCATTTTTTCTTCTCCTCTTCCCTTTCTAGCAAGTCTTTCTACTATTAATTCTGGC
GTACTTCTTCCAATAACTCC

Product: o-sialoglycoprotein endopeptidase

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MRGELKMKLIKQGAEAKIYLADFSELYYDLPIKVIVKERVSKRYRIPEIDIKLRKERTIREARILHRAKKAGVNVPYVFE
VDTKNMIIVMEFIEGERLKELLEKLPIEERLEICKEIGRVIGKLHEAGIVHGDLTTSNMIMRDGKIYLIDFGLAEFDDTL
EAQGVDLHLLRRAMESTHYSWVEEGFKAVLRGYEEVRGKEKRREIEEKIKEIELRGRYRERSWITS

Sequences:

>Translated_226_residues
MRGELKMKLIKQGAEAKIYLADFSELYYDLPIKVIVKERVSKRYRIPEIDIKLRKERTIREARILHRAKKAGVNVPYVFE
VDTKNMIIVMEFIEGERLKELLEKLPIEERLEICKEIGRVIGKLHEAGIVHGDLTTSNMIMRDGKIYLIDFGLAEFDDTL
EAQGVDLHLLRRAMESTHYSWVEEGFKAVLRGYEEVRGKEKRREIEEKIKEIELRGRYRERSWITS
>Mature_226_residues
MRGELKMKLIKQGAEAKIYLADFSELYYDLPIKVIVKERVSKRYRIPEIDIKLRKERTIREARILHRAKKAGVNVPYVFE
VDTKNMIIVMEFIEGERLKELLEKLPIEERLEICKEIGRVIGKLHEAGIVHGDLTTSNMIMRDGKIYLIDFGLAEFDDTL
EAQGVDLHLLRRAMESTHYSWVEEGFKAVLRGYEEVRGKEKRREIEEKIKEIELRGRYRERSWITS

Specific function: Unknown

COG id: COG3642

COG function: function code T; Mn2+-dependent serine/threonine protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI41327715, Length=224, Percent_Identity=36.1607142857143, Blast_Score=134, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6321701, Length=248, Percent_Identity=35.0806451612903, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24658177, Length=228, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022449
- InterPro:   IPR022495
- InterPro:   IPR011009
- InterPro:   IPR009220
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR008266 [H]

Pfam domain/function: PF00814 Peptidase_M22; PF00069 Pkinase [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 26680; Mature: 26680

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGELKMKLIKQGAEAKIYLADFSELYYDLPIKVIVKERVSKRYRIPEIDIKLRKERTIR
CCCCHHHHHHHCCCCCEEEEECHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHH
EARILHRAKKAGVNVPYVFEVDTKNMIIVMEFIEGERLKELLEKLPIEERLEICKEIGRV
HHHHHHHHHHCCCCCCEEEEECCCCEEEEEEHHCCHHHHHHHHHCCHHHHHHHHHHHHHH
IGKLHEAGIVHGDLTTSNMIMRDGKIYLIDFGLAEFDDTLEAQGVDLHLLRRAMESTHYS
HHHHHHCCEEECCCCCCCEEEECCEEEEEECCCHHHCHHHHCCCCHHHHHHHHHHHHHHH
WVEEGFKAVLRGYEEVRGKEKRREIEEKIKEIELRGRYRERSWITS
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHCCCCC
>Mature Secondary Structure
MRGELKMKLIKQGAEAKIYLADFSELYYDLPIKVIVKERVSKRYRIPEIDIKLRKERTIR
CCCCHHHHHHHCCCCCEEEEECHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHH
EARILHRAKKAGVNVPYVFEVDTKNMIIVMEFIEGERLKELLEKLPIEERLEICKEIGRV
HHHHHHHHHHCCCCCCEEEEECCCCEEEEEEHHCCHHHHHHHHHCCHHHHHHHHHHHHHH
IGKLHEAGIVHGDLTTSNMIMRDGKIYLIDFGLAEFDDTLEAQGVDLHLLRRAMESTHYS
HHHHHHCCEEECCCCCCCEEEECCEEEEEECCCHHHCHHHHCCCCHHHHHHHHHHHHHHH
WVEEGFKAVLRGYEEVRGKEKRREIEEKIKEIELRGRYRERSWITS
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]