BacMap

Definition	Pyrococcus furiosus DSM 3638, complete genome.
Accession	NC_003413
Length	1,908,256

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The map label for this gene is yocR [H]

Identifier: 18976743

GI number: 18976743

Start: 385602

End: 386894

Strand: Direct

Name: yocR [H]

Synonym: PF0371

Alternate gene names: 18976743

Gene position: 385602-386894 (Clockwise)

Preceding gene: 18976737

Following gene: 18976744

Centisome position: 20.21

GC content: 45.01

Gene sequence:

>1293_bases
GTGAAAGTTTTGGCAAGGGAAACTTGGGGGAGTAGAGTAGGTTTTGTTGCAGCTGCAATAGGAAGTGCTGTGGGACTTGG
AAACATCTGGATGTTTCCAATGAGGGCAGGACTCTATGGAGGAGCTGCATTTCTCATCCCATATTTAGTTCTATTGTTTG
CCGTGGGAGTAGTTGCCCTTACGGTAGAGTGGACGCTTGGAAGAGCAACAAAGGGCGGGCCAATTGAGGCGTTTGAAAAG
ACATTACCAGGTGGAAAATATCTAGGGATTCTGGTGAACGTAACTATCCTCATGATATTCGCCTTTTATTCCTTGGTGCT
CGGATGGGTGATCAGATACTTCATAGCTTCACTAAGCGGTGAGCTAACAAGGATAGAACCAGATAAGTTCTTTAACGCCC
TCGCCTTTAGCAGGGAGGCCCTCCTGTGGCTATTCGTAGTTATTGCATTAACAATAGCAATAGTAGCTATGGGTGTTCAG
AGAGGAATCGAGAGGGCAAACAAGATCATGATGCCTCTTCTCTTCGTTCTCCTAATCGTGTTGGCAGTTAGGAGCGTTAC
ACTACCAAACGCATACGAGGGCTTGAAGTTCTACCTACTACCAGATCTGAGCAAAATAGCAAGTGGAAAAACATGGATGA
TAGCACTCTCTCAGATGTTCTTCTCCCTAAGTGTTTTAGGGAATACAATGGTTGTTTATGGAAGCTATCTTAGAGAGGAG
GACGACATACCGTTATCAGCAATCGCCACTGCATTCGGTGATACTGCAGTAGCGGTCACTGCTGGATTTATAGTCTTTCC
AGCAGTCTTCTCATTTGGCCTTGAGCCCACAGCTGGCCCAGGGCTAGTGTTTGTAACCCTGCCAATGGTGTTCCAAAAAA
TGCCAGGAGGAATGATCTTCAGTGCATTGTTCTTCCTCTTGCTAATATTTGCAGGACTTTCTTCAACTGTTTCGATGCTT
GAAGTTTATGTTGATTCTGCAATAACAAAGCTCAAAATCAGCAGAAAAAATGCCTCAGTGCTTTTAGGCTTGCTAACTTT
CCTGGTGGGAGCACCTTCCGCACTTTATCCTGCCTACTTTGATTGGCTCATCAACATTTCAACCGTATACGTAGGTCCCC
TAGGAGCATTAATAGCAGCTCTTGCCCTCATAAAGCTGGGAGTTGATAGAGCATATGAAGAACTCCAAAAAGGTGCCCTT
ATTAAAGTGCCAGAGCTCTGGAAGCCCTGGGTTAAGTTCCTATATCCAATAGTGATAGTGGTAATATACATCTCCCAATT
CCTACTGGGGTGA

Upstream 100 bases:

>100_bases
TGGACAGTTTGAGTAATTGATGCCTTATGATAGGCAGGAGTGATCGTTTTTGGATGTTCTAGTCTTATTCTCCTGATTTG
TCTAACAAACCTTCTAGGAG

Downstream 100 bases:

>100_bases
GGAAAGTTGGATGTGGTTTACATAGCAGCCTTGATAGTAATCGTAATAGTCTATGGGCCTCTCTTGTGGGCTCTCTACAA
GCTCTCAAAGGCTTCTTAAT

Product: putative transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MKVLARETWGSRVGFVAAAIGSAVGLGNIWMFPMRAGLYGGAAFLIPYLVLLFAVGVVALTVEWTLGRATKGGPIEAFEK
TLPGGKYLGILVNVTILMIFAFYSLVLGWVIRYFIASLSGELTRIEPDKFFNALAFSREALLWLFVVIALTIAIVAMGVQ
RGIERANKIMMPLLFVLLIVLAVRSVTLPNAYEGLKFYLLPDLSKIASGKTWMIALSQMFFSLSVLGNTMVVYGSYLREE
DDIPLSAIATAFGDTAVAVTAGFIVFPAVFSFGLEPTAGPGLVFVTLPMVFQKMPGGMIFSALFFLLLIFAGLSSTVSML
EVYVDSAITKLKISRKNASVLLGLLTFLVGAPSALYPAYFDWLINISTVYVGPLGALIAALALIKLGVDRAYEELQKGAL
IKVPELWKPWVKFLYPIVIVVIYISQFLLG

Sequences:

>Translated_430_residues
MKVLARETWGSRVGFVAAAIGSAVGLGNIWMFPMRAGLYGGAAFLIPYLVLLFAVGVVALTVEWTLGRATKGGPIEAFEK
TLPGGKYLGILVNVTILMIFAFYSLVLGWVIRYFIASLSGELTRIEPDKFFNALAFSREALLWLFVVIALTIAIVAMGVQ
RGIERANKIMMPLLFVLLIVLAVRSVTLPNAYEGLKFYLLPDLSKIASGKTWMIALSQMFFSLSVLGNTMVVYGSYLREE
DDIPLSAIATAFGDTAVAVTAGFIVFPAVFSFGLEPTAGPGLVFVTLPMVFQKMPGGMIFSALFFLLLIFAGLSSTVSML
EVYVDSAITKLKISRKNASVLLGLLTFLVGAPSALYPAYFDWLINISTVYVGPLGALIAALALIKLGVDRAYEELQKGAL
IKVPELWKPWVKFLYPIVIVVIYISQFLLG
>Mature_430_residues
MKVLARETWGSRVGFVAAAIGSAVGLGNIWMFPMRAGLYGGAAFLIPYLVLLFAVGVVALTVEWTLGRATKGGPIEAFEK
TLPGGKYLGILVNVTILMIFAFYSLVLGWVIRYFIASLSGELTRIEPDKFFNALAFSREALLWLFVVIALTIAIVAMGVQ
RGIERANKIMMPLLFVLLIVLAVRSVTLPNAYEGLKFYLLPDLSKIASGKTWMIALSQMFFSLSVLGNTMVVYGSYLREE
DDIPLSAIATAFGDTAVAVTAGFIVFPAVFSFGLEPTAGPGLVFVTLPMVFQKMPGGMIFSALFFLLLIFAGLSSTVSML
EVYVDSAITKLKISRKNASVLLGLLTFLVGAPSALYPAYFDWLINISTVYVGPLGALIAALALIKLGVDRAYEELQKGAL
IKVPELWKPWVKFLYPIVIVVIYISQFLLG

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=407, Percent_Identity=27.027027027027, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI4507043, Length=400, Percent_Identity=26.5, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI171184408, Length=405, Percent_Identity=27.1604938271605, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI171184406, Length=405, Percent_Identity=27.1604938271605, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI171184404, Length=405, Percent_Identity=27.1604938271605, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI7657587, Length=378, Percent_Identity=27.7777777777778, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI188528618, Length=486, Percent_Identity=24.8971193415638, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI4507041, Length=388, Percent_Identity=25.5154639175258, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI197276623, Length=346, Percent_Identity=26.3005780346821, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI54607094, Length=346, Percent_Identity=26.3005780346821, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI289191351, Length=397, Percent_Identity=24.4332493702771, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI4557046, Length=397, Percent_Identity=24.4332493702771, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI289191377, Length=397, Percent_Identity=24.4332493702771, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI134304856, Length=344, Percent_Identity=26.453488372093, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI51468073, Length=519, Percent_Identity=23.5067437379576, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI194018524, Length=295, Percent_Identity=27.1186440677966, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI67782317, Length=420, Percent_Identity=26.9047619047619, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI67782313, Length=420, Percent_Identity=26.9047619047619, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI67782315, Length=420, Percent_Identity=26.9047619047619, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI58219014, Length=301, Percent_Identity=27.906976744186, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI5032097, Length=352, Percent_Identity=28.9772727272727, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI33354281, Length=302, Percent_Identity=25.8278145695364, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI11181770, Length=292, Percent_Identity=26.027397260274, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI6005715, Length=431, Percent_Identity=24.8259860788863, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI300360519, Length=370, Percent_Identity=24.5945945945946, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI218563756, Length=352, Percent_Identity=28.125, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI12408638, Length=270, Percent_Identity=24.8148148148148, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI197276625, Length=132, Percent_Identity=34.0909090909091, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI92859670, Length=185, Percent_Identity=28.1081081081081, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI21361693, Length=216, Percent_Identity=25.462962962963, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI289191353, Length=303, Percent_Identity=21.7821782178218, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI133952791, Length=496, Percent_Identity=25.8064516129032, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17555248, Length=415, Percent_Identity=26.5060240963855, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25146584, Length=406, Percent_Identity=25.8620689655172, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71995588, Length=391, Percent_Identity=23.0179028132992, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17554804, Length=353, Percent_Identity=25.7790368271955, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17569475, Length=399, Percent_Identity=24.0601503759398, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71998244, Length=345, Percent_Identity=27.536231884058, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17535731, Length=120, Percent_Identity=35, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17542050, Length=120, Percent_Identity=30.8333333333333, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI212642127, Length=98, Percent_Identity=32.6530612244898, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24762620, Length=481, Percent_Identity=29.1060291060291, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI17136952, Length=369, Percent_Identity=29.5392953929539, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI45550877, Length=417, Percent_Identity=25.8992805755396, Blast_Score=151, Evalue=8e-37,
Organism=Drosophila melanogaster, GI281364394, Length=369, Percent_Identity=29.5392953929539, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28574704, Length=369, Percent_Identity=29.5392953929539, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI17136950, Length=369, Percent_Identity=29.5392953929539, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28574702, Length=369, Percent_Identity=29.5392953929539, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI45551183, Length=417, Percent_Identity=25.8992805755396, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281365034, Length=492, Percent_Identity=27.0325203252033, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24661428, Length=407, Percent_Identity=28.7469287469287, Blast_Score=138, Evalue=9e-33,
Organism=Drosophila melanogaster, GI19921352, Length=497, Percent_Identity=26.1569416498994, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24584353, Length=497, Percent_Identity=26.1569416498994, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI19921936, Length=397, Percent_Identity=27.2040302267003, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281363702, Length=366, Percent_Identity=28.9617486338798, Blast_Score=121, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24652942, Length=373, Percent_Identity=27.3458445040214, Blast_Score=121, Evalue=9e-28,
Organism=Drosophila melanogaster, GI45551088, Length=373, Percent_Identity=27.3458445040214, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281364136, Length=392, Percent_Identity=27.0408163265306, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24582567, Length=413, Percent_Identity=25.90799031477, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24639514, Length=491, Percent_Identity=23.2179226069246, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221329674, Length=491, Percent_Identity=23.2179226069246, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281363700, Length=337, Percent_Identity=27.893175074184, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24639853, Length=507, Percent_Identity=24.65483234714, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24655079, Length=517, Percent_Identity=22.0502901353965, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24639516, Length=511, Percent_Identity=22.3091976516634, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24654186, Length=292, Percent_Identity=27.0547945205479, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24582569, Length=377, Percent_Identity=24.4031830238727, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 46726; Mature: 46726

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLARETWGSRVGFVAAAIGSAVGLGNIWMFPMRAGLYGGAAFLIPYLVLLFAVGVVAL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
TVEWTLGRATKGGPIEAFEKTLPGGKYLGILVNVTILMIFAFYSLVLGWVIRYFIASLSG
HHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ELTRIEPDKFFNALAFSREALLWLFVVIALTIAIVAMGVQRGIERANKIMMPLLFVLLIV
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVRSVTLPNAYEGLKFYLLPDLSKIASGKTWMIALSQMFFSLSVLGNTMVVYGSYLREE
HHHHHCCCCCHHCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCC
DDIPLSAIATAFGDTAVAVTAGFIVFPAVFSFGLEPTAGPGLVFVTLPMVFQKMPGGMIF
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHH
SALFFLLLIFAGLSSTVSMLEVYVDSAITKLKISRKNASVLLGLLTFLVGAPSALYPAYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHH
DWLINISTVYVGPLGALIAALALIKLGVDRAYEELQKGALIKVPELWKPWVKFLYPIVIV
HHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHH
VIYISQFLLG
HHHHHHHHCC
>Mature Secondary Structure
MKVLARETWGSRVGFVAAAIGSAVGLGNIWMFPMRAGLYGGAAFLIPYLVLLFAVGVVAL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
TVEWTLGRATKGGPIEAFEKTLPGGKYLGILVNVTILMIFAFYSLVLGWVIRYFIASLSG
HHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ELTRIEPDKFFNALAFSREALLWLFVVIALTIAIVAMGVQRGIERANKIMMPLLFVLLIV
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVRSVTLPNAYEGLKFYLLPDLSKIASGKTWMIALSQMFFSLSVLGNTMVVYGSYLREE
HHHHHCCCCCHHCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCC
DDIPLSAIATAFGDTAVAVTAGFIVFPAVFSFGLEPTAGPGLVFVTLPMVFQKMPGGMIF
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHH
SALFFLLLIFAGLSSTVSMLEVYVDSAITKLKISRKNASVLLGLLTFLVGAPSALYPAYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHH
DWLINISTVYVGPLGALIAALALIKLGVDRAYEELQKGALIKVPELWKPWVKFLYPIVIV
HHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHH
VIYISQFLLG
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]