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The map label for this gene is dppB [H]

Identifier: 18976730

GI number: 18976730

Start: 372068

End: 373060

Strand: Direct

Name: dppB [H]

Synonym: PF0358

Alternate gene names: 18976730

Gene position: 372068-373060 (Clockwise)

Preceding gene: 18976729

Following gene: 18976731

Centisome position: 19.5

GC content: 41.89

Gene sequence:

>993_bases
ATGGGGTTTAAAGAATATCTAAAGAGGAAAATTATTGTTTACCTCCTGACGTTTATTTTTGCTGTAACTTTAAACTGGTT
ACTTCCCAGGCTCATGCCCGGGGATCCAATTCAAATTATGATTAATTCTGCCTTAGGATTATCTCCCCAAGAGAGGGAAA
TATTATTGAGATTTTATGAAGAATTATATGGATTAAATAAGCCCCTTTACGCTCAGTTTGTTAGCTTCTGGGTGGCCCTC
TTCAAAGGGGATTTGGGATACAGCATACTTTATAGAGCTCCCGTTTCAAGGTTACTTAAGAATGCCCTCCCATATGACAT
TGCAATTTTGTTCCCAGCTATAGTATTAAGCTGGGTGATAGGAAACTGGTTGGGGGCACTAGCAGGCAAGAACAAAAGAT
ACGACACATATATGATGCCCCTATTTTATTTCCTAGCCAGCATGCCATACTTCTGGTTTGCAATGCTCCTCGTATACTTC
GTTGGTGTAAAGGCAGGAATCCTTCCTTATCAAGGGGCCTACAGCCCTAACCTAGTTCCAAGCCTTTCTCTAAGATTCAT
CGTGGATTTCCTCAAACACTGGATAATGCCATTTCTCAGCTTATTTGTCGTAATGATTGGCAGCTGGGCAATTGGTATGA
GAAATATGATAATATACGAGTTAGAAGCAGATTACGTAAGATACTTGGAGGCCCTTGGAGCAAGTGAAAAGCTAATGACA
AAACATGCATACAAGAATGCAATTCTGCCTCAAATTACAGGACTTGCGCTCCAGCTCGGTTTAATGGTAGCAGGAGCGAT
AGCTACTGAGATCGTCTTTAACTATCCAGGAGTGGGGGTCCTTTTAATGAGAGCTGCAATGAGCCAAGACTATTTTCTTC
TCCAAGGGGGTTTTCTAATGATCGTAATCTCAGTTCTCGTCGCCAACTTCCTGATAGATATCGCCTATGCCTTCATTGAT
CCACGTGTTAGGGCTAGCTATACGGAGGGATGA

Upstream 100 bases:

>100_bases
GGCCCGCAATTTTAGTAGGTCTAGCTGTAGTCCCACTCCTTCTAAGAAGGAGGAGGCGTTGAGTTTCTTCTTTTTCTAAA
TTTTTCTAGGGGGGAGTGTT

Downstream 100 bases:

>100_bases
TAAATGAAAACAATAAAGCTCGCATTCAAAAATAACAAATTTAAATTTGGATTTGGAATATTAGTAGCTTTTATAATCTT
TGGGCTAATTGGCCCGCTTT

Product: oppbc family ABC transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MGFKEYLKRKIIVYLLTFIFAVTLNWLLPRLMPGDPIQIMINSALGLSPQEREILLRFYEELYGLNKPLYAQFVSFWVAL
FKGDLGYSILYRAPVSRLLKNALPYDIAILFPAIVLSWVIGNWLGALAGKNKRYDTYMMPLFYFLASMPYFWFAMLLVYF
VGVKAGILPYQGAYSPNLVPSLSLRFIVDFLKHWIMPFLSLFVVMIGSWAIGMRNMIIYELEADYVRYLEALGASEKLMT
KHAYKNAILPQITGLALQLGLMVAGAIATEIVFNYPGVGVLLMRAAMSQDYFLLQGGFLMIVISVLVANFLIDIAYAFID
PRVRASYTEG

Sequences:

>Translated_330_residues
MGFKEYLKRKIIVYLLTFIFAVTLNWLLPRLMPGDPIQIMINSALGLSPQEREILLRFYEELYGLNKPLYAQFVSFWVAL
FKGDLGYSILYRAPVSRLLKNALPYDIAILFPAIVLSWVIGNWLGALAGKNKRYDTYMMPLFYFLASMPYFWFAMLLVYF
VGVKAGILPYQGAYSPNLVPSLSLRFIVDFLKHWIMPFLSLFVVMIGSWAIGMRNMIIYELEADYVRYLEALGASEKLMT
KHAYKNAILPQITGLALQLGLMVAGAIATEIVFNYPGVGVLLMRAAMSQDYFLLQGGFLMIVISVLVANFLIDIAYAFID
PRVRASYTEG
>Mature_329_residues
GFKEYLKRKIIVYLLTFIFAVTLNWLLPRLMPGDPIQIMINSALGLSPQEREILLRFYEELYGLNKPLYAQFVSFWVALF
KGDLGYSILYRAPVSRLLKNALPYDIAILFPAIVLSWVIGNWLGALAGKNKRYDTYMMPLFYFLASMPYFWFAMLLVYFV
GVKAGILPYQGAYSPNLVPSLSLRFIVDFLKHWIMPFLSLFVVMIGSWAIGMRNMIIYELEADYVRYLEALGASEKLMTK
HAYKNAILPQITGLALQLGLMVAGAIATEIVFNYPGVGVLLMRAAMSQDYFLLQGGFLMIVISVLVANFLIDIAYAFIDP
RVRASYTEG

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=29.2035398230088, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1787053, Length=323, Percent_Identity=27.5541795665635, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1787761, Length=341, Percent_Identity=28.1524926686217, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1789888, Length=325, Percent_Identity=28, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787497, Length=324, Percent_Identity=25.3086419753086, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788504, Length=361, Percent_Identity=24.3767313019391, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=27.6119402985075, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37536; Mature: 37404

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHCCHHCCCCCCC
>Mature Secondary Structure 
GFKEYLKRKIIVYLLTFIFAVTLNWLLPRLMPGDPIQIMINSALGLSPQEREILLRFYE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEHHHCCCCCHHHHHHHHHHH
ELYGLNKPLYAQFVSFWVALFKGDLGYSILYRAPVSRLLKNALPYDIAILFPAIVLSWVI
HHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GNWLGALAGKNKRYDTYMMPLFYFLASMPYFWFAMLLVYFVGVKAGILPYQGAYSPNLVP
HHHHHHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
SLSLRFIVDFLKHWIMPFLSLFVVMIGSWAIGMRNMIIYELEADYVRYLEALGASEKLMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHCCHHHHHH
KHAYKNAILPQITGLALQLGLMVAGAIATEIVFNYPGVGVLLMRAAMSQDYFLLQGGFLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEECCCHHH
IVISVLVANFLIDIAYAFIDPRVRASYTEG
HHHHHHHHHHHHHHHHHHHCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]