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The map label for this gene is yebU [C]

Identifier: 18976541

GI number: 18976541

Start: 178650

End: 179810

Strand: Direct

Name: yebU [C]

Synonym: PF0169

Alternate gene names: 18976541

Gene position: 178650-179810 (Clockwise)

Preceding gene: 18976540

Following gene: 18976542

Centisome position: 9.36

GC content: 40.31

Gene sequence:

>1161_bases
ATGAGCTATTTAGAAGCATTTCCTCCAGAGCTTCAGGAATATTATCGGAAACTTTTCGGGGAGGAAGCAGAAGAGATTAT
GAAAAGGCTTAGAGAGCCGGTTGAACACTACTACATTAGGGTTAATACCCTAAAGATTAGTCGGGAAAAGCTCATTGAAG
AACTAAGAAAGGAGGGCTTACGTCCAAGAAGGAGCCCCTACCTTCAAGAAGCTTTGTATTTTGTAAGGGAGGGGCCGAAC
TTTCCTGACGACTACAATCCAAATCTGCCAACAGTGGTTGCCAATAAGTATGCAGCAGAGAGCGTTTATCAAGGAGCCAT
GCTTTATGCTCCAGGCGTTCTCAAGGCTGAGAAAGGAATAAAAGAAGGGGATATGGTTCAAATTAGAGACCCAAGAGGAC
TTTTAGTTGGAATTGGAATAGCGAAAATGGACTACAGGGAAATGATAGAAGCTACTAGAGGGTTAGCAGTTGAAGTAACT
CTCCCAAAATTTAAGCTGCCTAGCTTAAGTGAGCTAAAATCTTTTGAGAAGGGTTATTTCTATCCTCAGAGTTTGCCATC
AATGGTGACTTCTAGAGTCTTAGAGCCTAAGGAAGAGGAAATTATAATAGACATGGCCGCTGCTCCTGGGGGTAAAACAT
CTCATATAGCTCAGCTTCTTCAAAATAGGGGGGAGATAATAGCCATAGACAAATCAAAGAACAGATTAAAGAAGATGGAA
GAAAATCTCAAAAGATTAGGAGTAAAAAACGTAAAATTAATTCAGATGGATGCTCGAAACCTTCCAGAGCTCGGAATTAA
GGCAGATAAGATACTTTTGGATGCTCCGTGTACTGCTTTGGGTGTAAGGCCAAAGCTTTGGGAATTGAGAACACCAAAGG
ATATTGAGGCCACTGCAAGATATCAAAGGGCATTTATCTGGGCTGCAATAAAAAGTCTAAGAAAAGGTGGGATATTAGTT
TATTCCACTTGCACTTTAAGTTATGAGGAAAATGAAGGAAATGTAAAGTTTATGCTCAAAAAAGGTATGAAGCTTGAAGA
GCAGAGCCTCTTTATTGGTTCTCCTGGAATAGGAATTGATGAGGTTCAGAGATTCTACCCACACAAACATCTAACTCAGG
GGTTCTTTATTGCAAAGTTAAGAAAGGTGAGAGAAATATGA

Upstream 100 bases:

>100_bases
AGGAGATGATAAACTTTGAGGTTGATCTTGGTTTCGACAAGGAGGAAGTTAAAAGAGAAATAAAGAGGTTTATTGAGCTG
GCAAGGAGGTACAACTTGCT

Downstream 100 bases:

>100_bases
AGATAAAGAAGAGATATGTAACTGTGGTAGCGGGGATTGGATTATTGGGAGTTCTTCTTTGGTGGGCAGGAATTAGAGAA
ACTCTAACATTGCTCTTTTC

Product: nol1-nop2-sun family nucleolar protein III

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSYLEAFPPELQEYYRKLFGEEAEEIMKRLREPVEHYYIRVNTLKISREKLIEELRKEGLRPRRSPYLQEALYFVREGPN
FPDDYNPNLPTVVANKYAAESVYQGAMLYAPGVLKAEKGIKEGDMVQIRDPRGLLVGIGIAKMDYREMIEATRGLAVEVT
LPKFKLPSLSELKSFEKGYFYPQSLPSMVTSRVLEPKEEEIIIDMAAAPGGKTSHIAQLLQNRGEIIAIDKSKNRLKKME
ENLKRLGVKNVKLIQMDARNLPELGIKADKILLDAPCTALGVRPKLWELRTPKDIEATARYQRAFIWAAIKSLRKGGILV
YSTCTLSYEENEGNVKFMLKKGMKLEEQSLFIGSPGIGIDEVQRFYPHKHLTQGFFIAKLRKVREI

Sequences:

>Translated_386_residues
MSYLEAFPPELQEYYRKLFGEEAEEIMKRLREPVEHYYIRVNTLKISREKLIEELRKEGLRPRRSPYLQEALYFVREGPN
FPDDYNPNLPTVVANKYAAESVYQGAMLYAPGVLKAEKGIKEGDMVQIRDPRGLLVGIGIAKMDYREMIEATRGLAVEVT
LPKFKLPSLSELKSFEKGYFYPQSLPSMVTSRVLEPKEEEIIIDMAAAPGGKTSHIAQLLQNRGEIIAIDKSKNRLKKME
ENLKRLGVKNVKLIQMDARNLPELGIKADKILLDAPCTALGVRPKLWELRTPKDIEATARYQRAFIWAAIKSLRKGGILV
YSTCTLSYEENEGNVKFMLKKGMKLEEQSLFIGSPGIGIDEVQRFYPHKHLTQGFFIAKLRKVREI
>Mature_385_residues
SYLEAFPPELQEYYRKLFGEEAEEIMKRLREPVEHYYIRVNTLKISREKLIEELRKEGLRPRRSPYLQEALYFVREGPNF
PDDYNPNLPTVVANKYAAESVYQGAMLYAPGVLKAEKGIKEGDMVQIRDPRGLLVGIGIAKMDYREMIEATRGLAVEVTL
PKFKLPSLSELKSFEKGYFYPQSLPSMVTSRVLEPKEEEIIIDMAAAPGGKTSHIAQLLQNRGEIIAIDKSKNRLKKMEE
NLKRLGVKNVKLIQMDARNLPELGIKADKILLDAPCTALGVRPKLWELRTPKDIEATARYQRAFIWAAIKSLRKGGILVY
STCTLSYEENEGNVKFMLKKGMKLEEQSLFIGSPGIGIDEVQRFYPHKHLTQGFFIAKLRKVREI

Specific function: May act as RNA methyltransferase [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI32698918, Length=404, Percent_Identity=30.6930693069307, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI76150625, Length=223, Percent_Identity=39.9103139013453, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI76150623, Length=223, Percent_Identity=39.9103139013453, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI270288818, Length=237, Percent_Identity=30.379746835443, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI23199998, Length=237, Percent_Identity=30.379746835443, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI8922322, Length=237, Percent_Identity=30.379746835443, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI270288816, Length=237, Percent_Identity=30.379746835443, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI301336155, Length=201, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI39995082, Length=201, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI87081985, Length=225, Percent_Identity=36, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI2367212, Length=249, Percent_Identity=32.5301204819277, Blast_Score=109, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17536757, Length=225, Percent_Identity=36.4444444444444, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI25143471, Length=194, Percent_Identity=28.8659793814433, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI115534021, Length=229, Percent_Identity=26.6375545851528, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71998419, Length=229, Percent_Identity=26.6375545851528, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324268, Length=225, Percent_Identity=36, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319447, Length=271, Percent_Identity=26.5682656826568, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24668781, Length=417, Percent_Identity=31.6546762589928, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI21356513, Length=342, Percent_Identity=33.0409356725146, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI22024126, Length=223, Percent_Identity=35.4260089686099, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI21356579, Length=224, Percent_Identity=29.4642857142857, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19920494, Length=163, Percent_Identity=36.1963190184049, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR011023 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu [H]

EC number: NA

Molecular weight: Translated: 44201; Mature: 44070

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50890 PUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLEAFPPELQEYYRKLFGEEAEEIMKRLREPVEHYYIRVNTLKISREKLIEELRKEGL
CCCHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEEEEECCHHHHHHHHHHCCC
RPRRSPYLQEALYFVREGPNFPDDYNPNLPTVVANKYAAESVYQGAMLYAPGVLKAEKGI
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEECCCCHHHHCCC
KEGDMVQIRDPRGLLVGIGIAKMDYREMIEATRGLAVEVTLPKFKLPSLSELKSFEKGYF
CCCCEEEEECCCCEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCC
YPQSLPSMVTSRVLEPKEEEIIIDMAAAPGGKTSHIAQLLQNRGEIIAIDKSKNRLKKME
CHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHH
ENLKRLGVKNVKLIQMDARNLPELGIKADKILLDAPCTALGVRPKLWELRTPKDIEATAR
HHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCCHHHHHH
YQRAFIWAAIKSLRKGGILVYSTCTLSYEENEGNVKFMLKKGMKLEEQSLFIGSPGIGID
HHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCCEEEEEECCCCCCCCEEEECCCCCCHH
EVQRFYPHKHLTQGFFIAKLRKVREI
HHHHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SYLEAFPPELQEYYRKLFGEEAEEIMKRLREPVEHYYIRVNTLKISREKLIEELRKEGL
CCHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEEEEECCHHHHHHHHHHCCC
RPRRSPYLQEALYFVREGPNFPDDYNPNLPTVVANKYAAESVYQGAMLYAPGVLKAEKGI
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEECCCCHHHHCCC
KEGDMVQIRDPRGLLVGIGIAKMDYREMIEATRGLAVEVTLPKFKLPSLSELKSFEKGYF
CCCCEEEEECCCCEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCC
YPQSLPSMVTSRVLEPKEEEIIIDMAAAPGGKTSHIAQLLQNRGEIIAIDKSKNRLKKME
CHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHH
ENLKRLGVKNVKLIQMDARNLPELGIKADKILLDAPCTALGVRPKLWELRTPKDIEATAR
HHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCCHHHHHH
YQRAFIWAAIKSLRKGGILVYSTCTLSYEENEGNVKFMLKKGMKLEEQSLFIGSPGIGID
HHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCCEEEEEECCCCCCCCEEEECCCCCCHH
EVQRFYPHKHLTQGFFIAKLRKVREI
HHHHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]