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The map label for this gene is ywoG [H]

Identifier: 18976515

GI number: 18976515

Start: 152568

End: 153731

Strand: Direct

Name: ywoG [H]

Synonym: PF0143

Alternate gene names: 18976515

Gene position: 152568-153731 (Clockwise)

Preceding gene: 18976514

Following gene: 18976516

Centisome position: 8.0

GC content: 40.72

Gene sequence:

>1164_bases
ATGCTTAAAAGTCTTTGGTATCTAAACTTTTCCACACTATTCTTTTTCCTGGGGGTAAGCATACTTAACCCGTTAGTTTC
CCCTTATGCCATAACATTAGGGGCCACTCCCGTCATAGTAGGAATCGTGGCTGGAACTGTTTCTATTGTTTCCCTCTCCT
CAAAACCACTTGGTGGATACCTGGGAGATAGGGGTTTTAAGTTCCATGCAATGTTTATTGGAAACATAATTGGGATAATA
GCTGTTCTTTTATACGTTCTATCTAATATTTTAGGAAATATATGGGTATTTGCCTTGGGCAGAGCAGTCCACGGTTTTGC
AATGGGGATCTTCTTTCCCTCCTCTCTTGCATTAGCTGTCGACTTGGCACCTAAAGGGAGAGTGGGAGAATCGCTCGGCT
GGAGAGGAATGATGTTTTCTCTAGGGAATATAGTGGGTCCCGGAATTGGAGGGTTTATATCTGATAATTTTGGATTTGTT
AGTGCATTCATCTTCAGTGGAATATTCTCTTTTATTGGATCACTATTTGTTTTGATAGTATGGAGAGAAATAGGCAGTGT
TAAGAGCGAAAAGGCATCAGAGAGAGGTAATTATAGAGAATTACTTAGGAGGTCATTTGTTTCGGCATCAGTTTCCCTAT
TTTTGATATCCATGGCTTATTCTGGTGTTGTAACTTATCTACCCGCTCTTTACAAGGTTTCTGGTTTTGGTCAGAGCGTG
TTCGGGATGTACATGATGTTTGTGGGCATTGCAAGCTTTATAATGAGAGTTTTTGGAGGTAAGATTGCCGATATTAAGGG
TCCAATTCCAGTTGCGAGAGTGGGAATATTAATTTTGGGATCTTCATACTTGGCATTGGCTTTTAATCAATATCCTCCAT
TCTCCTTTATAGTTGGAGTTGTATCTGGATTAGGATTTGGTCTCCTCATTCCTGCATTGCAATATATGGCATTGGCCAAT
CTCCCAGGAAACATTAGAACAATGGGTTCGAGCATTTATACGATGTTCTTTGACCTGGGAATGTTATCGGGGCAACTAGC
CTTTGGAGTTGTTGCTGAAGTTAGAGGGTATGAGGGAATATTTCCCTTTATTGCTCTGCTCCCATTCGTGTCCCTTATAA
CTGTACATTTCCCATTATTAAGGAGGGAAGGAAATGAAGGTTAG

Upstream 100 bases:

>100_bases
TGGTTGACTCTAATGGGAATGTTGGCTTTGCTAAGAATACAAAACACATGAGTTACGCATTTATGAAGGAAGGCATGAAG
GAACCGGAGGCAGGGGTGTA

Downstream 100 bases:

>100_bases
AGTTTCATATGGAACGGCTATAGCCATGGGGCTAATTAAGGCCAAGATGCTCTCTAGCCCTACTACAGCTTATCTCATGA
CGTATCACAATGGGAGATGT

Product: quinolone resistance protein norA - like protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MLKSLWYLNFSTLFFFLGVSILNPLVSPYAITLGATPVIVGIVAGTVSIVSLSSKPLGGYLGDRGFKFHAMFIGNIIGII
AVLLYVLSNILGNIWVFALGRAVHGFAMGIFFPSSLALAVDLAPKGRVGESLGWRGMMFSLGNIVGPGIGGFISDNFGFV
SAFIFSGIFSFIGSLFVLIVWREIGSVKSEKASERGNYRELLRRSFVSASVSLFLISMAYSGVVTYLPALYKVSGFGQSV
FGMYMMFVGIASFIMRVFGGKIADIKGPIPVARVGILILGSSYLALAFNQYPPFSFIVGVVSGLGFGLLIPALQYMALAN
LPGNIRTMGSSIYTMFFDLGMLSGQLAFGVVAEVRGYEGIFPFIALLPFVSLITVHFPLLRREGNEG

Sequences:

>Translated_387_residues
MLKSLWYLNFSTLFFFLGVSILNPLVSPYAITLGATPVIVGIVAGTVSIVSLSSKPLGGYLGDRGFKFHAMFIGNIIGII
AVLLYVLSNILGNIWVFALGRAVHGFAMGIFFPSSLALAVDLAPKGRVGESLGWRGMMFSLGNIVGPGIGGFISDNFGFV
SAFIFSGIFSFIGSLFVLIVWREIGSVKSEKASERGNYRELLRRSFVSASVSLFLISMAYSGVVTYLPALYKVSGFGQSV
FGMYMMFVGIASFIMRVFGGKIADIKGPIPVARVGILILGSSYLALAFNQYPPFSFIVGVVSGLGFGLLIPALQYMALAN
LPGNIRTMGSSIYTMFFDLGMLSGQLAFGVVAEVRGYEGIFPFIALLPFVSLITVHFPLLRREGNEG
>Mature_387_residues
MLKSLWYLNFSTLFFFLGVSILNPLVSPYAITLGATPVIVGIVAGTVSIVSLSSKPLGGYLGDRGFKFHAMFIGNIIGII
AVLLYVLSNILGNIWVFALGRAVHGFAMGIFFPSSLALAVDLAPKGRVGESLGWRGMMFSLGNIVGPGIGGFISDNFGFV
SAFIFSGIFSFIGSLFVLIVWREIGSVKSEKASERGNYRELLRRSFVSASVSLFLISMAYSGVVTYLPALYKVSGFGQSV
FGMYMMFVGIASFIMRVFGGKIADIKGPIPVARVGILILGSSYLALAFNQYPPFSFIVGVVSGLGFGLLIPALQYMALAN
LPGNIRTMGSSIYTMFFDLGMLSGQLAFGVVAEVRGYEGIFPFIALLPFVSLITVHFPLLRREGNEG

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41563; Mature: 41563

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKSLWYLNFSTLFFFLGVSILNPLVSPYAITLGATPVIVGIVAGTVSIVSLSSKPLGGY
CCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHEECCCCCCCC
LGDRGFKFHAMFIGNIIGIIAVLLYVLSNILGNIWVFALGRAVHGFAMGIFFPSSLALAV
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
DLAPKGRVGESLGWRGMMFSLGNIVGPGIGGFISDNFGFVSAFIFSGIFSFIGSLFVLIV
ECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WREIGSVKSEKASERGNYRELLRRSFVSASVSLFLISMAYSGVVTYLPALYKVSGFGQSV
HHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
FGMYMMFVGIASFIMRVFGGKIADIKGPIPVARVGILILGSSYLALAFNQYPPFSFIVGV
HHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHCCCCHHEEEECCCCCHHHHHHH
VSGLGFGLLIPALQYMALANLPGNIRTMGSSIYTMFFDLGMLSGQLAFGVVAEVRGYEGI
HHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCH
FPFIALLPFVSLITVHFPLLRREGNEG
HHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLKSLWYLNFSTLFFFLGVSILNPLVSPYAITLGATPVIVGIVAGTVSIVSLSSKPLGGY
CCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHEECCCCCCCC
LGDRGFKFHAMFIGNIIGIIAVLLYVLSNILGNIWVFALGRAVHGFAMGIFFPSSLALAV
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
DLAPKGRVGESLGWRGMMFSLGNIVGPGIGGFISDNFGFVSAFIFSGIFSFIGSLFVLIV
ECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WREIGSVKSEKASERGNYRELLRRSFVSASVSLFLISMAYSGVVTYLPALYKVSGFGQSV
HHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
FGMYMMFVGIASFIMRVFGGKIADIKGPIPVARVGILILGSSYLALAFNQYPPFSFIVGV
HHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHCCCCHHEEEECCCCCHHHHHHH
VSGLGFGLLIPALQYMALANLPGNIRTMGSSIYTMFFDLGMLSGQLAFGVVAEVRGYEGI
HHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCH
FPFIALLPFVSLITVHFPLLRREGNEG
HHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]