Click here to switch to the map view.

The map label for this gene is moeB [H]

Identifier: 18976381

GI number: 18976381

Start: 8538

End: 9230

Strand: Direct

Name: moeB [H]

Synonym: PF0009

Alternate gene names: 18976381

Gene position: 8538-9230 (Clockwise)

Preceding gene: 18976380

Following gene: 161484715

Centisome position: 0.45

GC content: 43.15

Gene sequence:

>693_bases
ATGCTGAGTGAAAGAGAGCTTGAGCGATACGACAGACAGATAATGATCTTCGGCATTGAAGGACAGGAAAAGCTGAAAAA
AGCCAATGTTGCTGTTGTTGGAGTAGGAGGACTAGGCAGCCCTGTCGCCTATTACCTAGCTGCTGCCGGAGTTGGAACAA
TTCTCTTAATAGACGAGCAGACTCCAGAGCTCAGCAACTTAAACAGACAGATACTCCACTGGGAGGAGGATATTGAGAAA
AACCCCAAACCAATATCCGCAAAGTGGAAACTTGAAAGGTTCAACTCGAACATAAAAATTGAGACATTTGTTGGGAGGTT
AAGTGAGGAGAACATCGACGAAGTTCTCTCCGGGGTTGATGTAATCGTTGATTGCCTGGATAACTTTGAGACAAGATACT
TACTTGATGATTTTGCACACAAGAAGGGAATACCCCTCGTTCACGGGGCCGTAGAGGGGTTTTATGGACAAGTAACTACA
ATAATCCCAGGAAAGACAAAGAGACTCAGAGAAATATTTCCCAAGGTTAAAAAGAAGGGCAAATTCCCAATAGTCGGGGC
AACCGCTGGAGTAATAGGAACTATCCAGGCAAGTGAGGTAATAAAGCTAATTACAGGATATGGCGAGCCACTTGCAAATA
AGCTTTTGATTATAGACTTGGCGAACAACACCTACGAAATAATCGAAATTTAA

Upstream 100 bases:

>100_bases
GATACAAACTTCATGCCAGTAATAGCGGACACAAAAGTAATTCCTGAGTCACTGGAGCAAGCATATGAAGAGCTCAAGAA
AGCTTTAGAGGAGATAGAAA

Downstream 100 bases:

>100_bases
ATTAGGGCTCAGCCACTCTGGGGCCAATCATCGCCTTTGCTCAGCATTGGATTCAGTCGTCATCGCCTAAGTGAAAATAC
TTGATAGCACTTGAAAAATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MLSERELERYDRQIMIFGIEGQEKLKKANVAVVGVGGLGSPVAYYLAAAGVGTILLIDEQTPELSNLNRQILHWEEDIEK
NPKPISAKWKLERFNSNIKIETFVGRLSEENIDEVLSGVDVIVDCLDNFETRYLLDDFAHKKGIPLVHGAVEGFYGQVTT
IIPGKTKRLREIFPKVKKKGKFPIVGATAGVIGTIQASEVIKLITGYGEPLANKLLIIDLANNTYEIIEI

Sequences:

>Translated_230_residues
MLSERELERYDRQIMIFGIEGQEKLKKANVAVVGVGGLGSPVAYYLAAAGVGTILLIDEQTPELSNLNRQILHWEEDIEK
NPKPISAKWKLERFNSNIKIETFVGRLSEENIDEVLSGVDVIVDCLDNFETRYLLDDFAHKKGIPLVHGAVEGFYGQVTT
IIPGKTKRLREIFPKVKKKGKFPIVGATAGVIGTIQASEVIKLITGYGEPLANKLLIIDLANNTYEIIEI
>Mature_230_residues
MLSERELERYDRQIMIFGIEGQEKLKKANVAVVGVGGLGSPVAYYLAAAGVGTILLIDEQTPELSNLNRQILHWEEDIEK
NPKPISAKWKLERFNSNIKIETFVGRLSEENIDEVLSGVDVIVDCLDNFETRYLLDDFAHKKGIPLVHGAVEGFYGQVTT
IIPGKTKRLREIFPKVKKKGKFPIVGATAGVIGTIQASEVIKLITGYGEPLANKLLIIDLANNTYEIIEI

Specific function: Involved In The Biosynthesis Of A Demolybdo Cofactor (Molybdopterin), Necessary For Molybdoenzymes. Plays A Role In The Activation Of The Small Subunit Of The Molybdopterin Converting Factor (Moad). [C]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=226, Percent_Identity=38.0530973451327, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI23510338, Length=149, Percent_Identity=31.5436241610738, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI23510340, Length=149, Percent_Identity=31.5436241610738, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI150417996, Length=170, Percent_Identity=32.9411764705882, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI38045948, Length=168, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787048, Length=225, Percent_Identity=36, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI87082356, Length=236, Percent_Identity=33.4745762711864, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1789177, Length=148, Percent_Identity=25, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17540406, Length=228, Percent_Identity=35.0877192982456, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI193203301, Length=165, Percent_Identity=28.4848484848485, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI86565433, Length=175, Percent_Identity=30.8571428571429, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI86565431, Length=175, Percent_Identity=30.8571428571429, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321903, Length=215, Percent_Identity=36.7441860465116, Blast_Score=119, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6320598, Length=183, Percent_Identity=31.1475409836066, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322639, Length=176, Percent_Identity=31.25, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24582879, Length=237, Percent_Identity=39.662447257384, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28573937, Length=167, Percent_Identity=34.1317365269461, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24660640, Length=169, Percent_Identity=31.9526627218935, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 25549; Mature: 25549

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSERELERYDRQIMIFGIEGQEKLKKANVAVVGVGGLGSPVAYYLAAAGVGTILLIDEQ
CCCHHHHHHCCCEEEEEECCCHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECC
TPELSNLNRQILHWEEDIEKNPKPISAKWKLERFNSNIKIETFVGRLSEENIDEVLSGVD
CCCHHCCCHHHHCCHHHHCCCCCCCCCEEEEECCCCCEEEEEEEHHCCCCCHHHHHHHHH
VIVDCLDNFETRYLLDDFAHKKGIPLVHGAVEGFYGQVTTIIPGKTKRLREIFPKVKKKG
HHHHHHHCCCHHHHHHHHHHHCCCCEEEHHHHHHCCEEEEECCCCHHHHHHHHHHHHHCC
KFPIVGATAGVIGTIQASEVIKLITGYGEPLANKLLIIDLANNTYEIIEI
CCCEEEECCCEEEECCHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEC
>Mature Secondary Structure
MLSERELERYDRQIMIFGIEGQEKLKKANVAVVGVGGLGSPVAYYLAAAGVGTILLIDEQ
CCCHHHHHHCCCEEEEEECCCHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECC
TPELSNLNRQILHWEEDIEKNPKPISAKWKLERFNSNIKIETFVGRLSEENIDEVLSGVD
CCCHHCCCHHHHCCHHHHCCCCCCCCCEEEEECCCCCEEEEEEEHHCCCCCHHHHHHHHH
VIVDCLDNFETRYLLDDFAHKKGIPLVHGAVEGFYGQVTTIIPGKTKRLREIFPKVKKKG
HHHHHHHCCCHHHHHHHHHHHCCCCEEEHHHHHHCCEEEEECCCCHHHHHHHHHHHHHCC
KFPIVGATAGVIGTIQASEVIKLITGYGEPLANKLLIIDLANNTYEIIEI
CCCEEEECCCEEEECCHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA