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The map label for this gene is ptxB [H]

Identifier: 189424218

GI number: 189424218

Start: 1206312

End: 1207223

Strand: Reverse

Name: ptxB [H]

Synonym: Glov_1153

Alternate gene names: 189424218

Gene position: 1207223-1206312 (Counterclockwise)

Preceding gene: 189424226

Following gene: 189424217

Centisome position: 30.81

GC content: 57.02

Gene sequence:

>912_bases
ATGACTGTACTCCCCCTACAACGGTTCGGCCTTTCAGGCAGCTTGTTTGCAGCAGCAGTGGCGCTCTGCACCTTTCTGCT
GTGTGTACCGCCGGCGGCCGAAGCTGCCGGAAAGCCGTTGATCCGCTTTGGTGTGATTCCCCGCTATAACCCGCTGGTCA
TGTACAAGCGTTACCAGCCGATCATGGATTATCTGACCGCCGAAACCCCCTACCGTTTTGAACTGAAGATCAGCAAAGAC
TACCCTGAGGCGGTCCGTTTTCTGCAACAGGGGGTAACCCAGATCAGCTCACTGGGGGATGTGACCTTTGCCGAAGCCAA
TCTGCGCTACCAGGCCATGCCGATCCTGAAACCGCTCAACAAAGAGGGTGTTCCCTTTTACCGCAGCGCCATCATTGTCC
GCAACGACTCTGCATTGAGGAGCATTACAGAATTAAAGGGCAAGACCATGGCCTTCGGCTCACCGCATTCCACCTCAGGC
AACCTGATCCCGCGCTATCTGCTCTGGGACAACAAGGTACGCATGCAGGATCTGAAATCCTTCACCAACCTGCAGCACCA
CGATGCCGTGGCCAAGGCGATCCTGAAAGGTCAGTTTGATGCCGGCGCCGTCAAGGATGTGGTGGCCGAAAAATACAAAC
CGCACGGCCTGCGAATCCTGGCTTGGTCCAAACCGATCCCGGCCGTGCCGCTGGTGGTCAGGCGGGACACGCCGCCAGAG
GTGGTGGAGGCAATTACCCGGGCACTCCTCAAGCTGGATCGCACCACCCCCCGGCACAAGGCGATTATGAAAAACTGGGA
TGATGAGTTCAACAACGGTTTTGCCACAGCCCGTCAGCAGGATTATGCCGACATCTTCCGTATGATCCGTGCCATACCAA
CCGGCTGCGGCATCGGATGCCACCACAAATGA

Upstream 100 bases:

>100_bases
GCGGAGCCTGGTTTCTTCCGACAGGGATTTGAAGAGATAGGCAACCTGTTTCATATCAAAACAAATATCCGCATAAGCGG
ATGAGGTCAAGCAGAAAATC

Downstream 100 bases:

>100_bases
CCCGCCGCTTTATCAGCATCAAGACGCAGTTTGTGCTGATTGCCATGCTGATGGTGGCACTGTCGTCAACACTGTGGGGC
GTTTTTGCCTGGAAGACCGA

Product: phosphonate ABC transporter periplasmic phosphonate-binding protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MTVLPLQRFGLSGSLFAAAVALCTFLLCVPPAAEAAGKPLIRFGVIPRYNPLVMYKRYQPIMDYLTAETPYRFELKISKD
YPEAVRFLQQGVTQISSLGDVTFAEANLRYQAMPILKPLNKEGVPFYRSAIIVRNDSALRSITELKGKTMAFGSPHSTSG
NLIPRYLLWDNKVRMQDLKSFTNLQHHDAVAKAILKGQFDAGAVKDVVAEKYKPHGLRILAWSKPIPAVPLVVRRDTPPE
VVEAITRALLKLDRTTPRHKAIMKNWDDEFNNGFATARQQDYADIFRMIRAIPTGCGIGCHHK

Sequences:

>Translated_303_residues
MTVLPLQRFGLSGSLFAAAVALCTFLLCVPPAAEAAGKPLIRFGVIPRYNPLVMYKRYQPIMDYLTAETPYRFELKISKD
YPEAVRFLQQGVTQISSLGDVTFAEANLRYQAMPILKPLNKEGVPFYRSAIIVRNDSALRSITELKGKTMAFGSPHSTSG
NLIPRYLLWDNKVRMQDLKSFTNLQHHDAVAKAILKGQFDAGAVKDVVAEKYKPHGLRILAWSKPIPAVPLVVRRDTPPE
VVEAITRALLKLDRTTPRHKAIMKNWDDEFNNGFATARQQDYADIFRMIRAIPTGCGIGCHHK
>Mature_302_residues
TVLPLQRFGLSGSLFAAAVALCTFLLCVPPAAEAAGKPLIRFGVIPRYNPLVMYKRYQPIMDYLTAETPYRFELKISKDY
PEAVRFLQQGVTQISSLGDVTFAEANLRYQAMPILKPLNKEGVPFYRSAIIVRNDSALRSITELKGKTMAFGSPHSTSGN
LIPRYLLWDNKVRMQDLKSFTNLQHHDAVAKAILKGQFDAGAVKDVVAEKYKPHGLRILAWSKPIPAVPLVVRRDTPPEV
VEAITRALLKLDRTTPRHKAIMKNWDDEFNNGFATARQQDYADIFRMIRAIPTGCGIGCHHK

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790543, Length=260, Percent_Identity=25.3846153846154, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 33982; Mature: 33851

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLPLQRFGLSGSLFAAAVALCTFLLCVPPAAEAAGKPLIRFGVIPRYNPLVMYKRYQP
CCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCEEEECCCCCCCCEEEEHHHHH
IMDYLTAETPYRFELKISKDYPEAVRFLQQGVTQISSLGDVTFAEANLRYQAMPILKPLN
HHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEHHHCCCC
KEGVPFYRSAIIVRNDSALRSITELKGKTMAFGSPHSTSGNLIPRYLLWDNKVRMQDLKS
CCCCCHHHEEEEEECCHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEECCCHHHHHHHH
FTNLQHHDAVAKAILKGQFDAGAVKDVVAEKYKPHGLRILAWSKPIPAVPLVVRRDTPPE
HHCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCCCHH
VVEAITRALLKLDRTTPRHKAIMKNWDDEFNNGFATARQQDYADIFRMIRAIPTGCGIGC
HHHHHHHHHHHHHCCCHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
HHK
CCC
>Mature Secondary Structure 
TVLPLQRFGLSGSLFAAAVALCTFLLCVPPAAEAAGKPLIRFGVIPRYNPLVMYKRYQP
CCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCEEEECCCCCCCCEEEEHHHHH
IMDYLTAETPYRFELKISKDYPEAVRFLQQGVTQISSLGDVTFAEANLRYQAMPILKPLN
HHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEHHHCCCC
KEGVPFYRSAIIVRNDSALRSITELKGKTMAFGSPHSTSGNLIPRYLLWDNKVRMQDLKS
CCCCCHHHEEEEEECCHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEECCCHHHHHHHH
FTNLQHHDAVAKAILKGQFDAGAVKDVVAEKYKPHGLRILAWSKPIPAVPLVVRRDTPPE
HHCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCCCHH
VVEAITRALLKLDRTTPRHKAIMKNWDDEFNNGFATARQQDYADIFRMIRAIPTGCGIGC
HHHHHHHHHHHHHCCCHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
HHK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]