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The map label for this gene is surA [H]

Identifier: 189423767

GI number: 189423767

Start: 707640

End: 708707

Strand: Reverse

Name: surA [H]

Synonym: Glov_0698

Alternate gene names: 189423767

Gene position: 708707-707640 (Counterclockwise)

Preceding gene: 189423768

Following gene: 189423760

Centisome position: 18.09

GC content: 54.03

Gene sequence:

>1068_bases
ATGAATCATCTTCGCCTGCTTTCCCTTGCCTCCCTCCTGAGCATATCTCTGCTGGGAGGTTGCGCATCCACCCCCGATGT
CATAACAGACACCGCCAAACAGCAACCACCAACCCTTACGGTGCCAAAACTCGCACCGCTTCCAGCCGGCGCCAAGCGTA
TTAATGGTGTTGCAGCCATTGTCAATGACGATATCATCACCTTCCGGGAGGTACTGCGCGAATCCCAGGCGGTCATTCAG
GATGCCCAGAAAAAAGGGCTCGTGGATGACACGGCTCGTCACAATCTGCGCGTCATGGTGCTAGACCGGCTGATTGAGAA
ACTCCTGACCGAGCAGAAGATTAAAGAACTGGGTATCAAGATCGGTGATGATGAAATCCGCCAAGCCATTGATGACGTCA
AGCGCCAGAACAACAATATGACCCAGAGTCAACTGGAGGCAGCGCTTAAATCCCAGGGCTACACGTTTGCCCAGTATGAG
GTCCAGCTCCGCGAACAGTTGGAACGGCTGCGTCTGGTGAGTATGGAAGTTCGCTCAAAGATATATGTCAGCGAAAAGGA
AGCGGAAGAGTATTATCAGTCCCATCTGAGCAGTTATGCCGAAGAAGAGACCTTCAAGGCCAGTCACATCTTTATCAAGG
TTGACGAAAAGGCCCCCGCCGATCAGATTCAACAGGCCATGAACAAGGCCCTGAAGGTGCTGTTTGAGGCCCGGCAGGGC
AAGGACTTTGCTCAACTAGCCAGGGAATACTCCGACGACGCGGCGGCAAAGAAGGATGGTGGCAGCCTGGGAACGTTTAA
ACGGGGAGAGATGCTGGCGGACCTTGAAAAGGCGATCCTGCCGCTCAAACCGGGCGAGGTCGGCGAACTGGTTTCAACCC
CGTCCGGATTGCACATTGTTAAGCTGGATGAGCGCTCAAGCGGTAAAGTCAAGCCCTTTGAGACCGTCAAGGCCGATATC
TCAGACCTGCTCTACCGCCAGAAGCAGGATAGCCGCTTTACCTCCTGGATGAAGGAACTGCGGACAAAGGCCAGCATCGA
GATCAAAGACGGGACCGGACTTATCTGA

Upstream 100 bases:

>100_bases
CGCTCCAGCTCCAGCTCCTGCAGCAGAAAAGAAATAATCGCTATTAACGTGATCCAGGCCGGGCAGCCAGTTGGTTGCCC
GGCCTGCTTTCGAGGCCTTC

Downstream 100 bases:

>100_bases
CTTTTCTCGAAAGCCCCCTGCGCTGCGGCCTCTGTGCCAAACAGGAAAAGCCCCGGCAACCGTTCTGGTTTGCCGGGGCT
TTCCTGTTATGTTCTCCGTC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MNHLRLLSLASLLSISLLGGCASTPDVITDTAKQQPPTLTVPKLAPLPAGAKRINGVAAIVNDDIITFREVLRESQAVIQ
DAQKKGLVDDTARHNLRVMVLDRLIEKLLTEQKIKELGIKIGDDEIRQAIDDVKRQNNNMTQSQLEAALKSQGYTFAQYE
VQLREQLERLRLVSMEVRSKIYVSEKEAEEYYQSHLSSYAEEETFKASHIFIKVDEKAPADQIQQAMNKALKVLFEARQG
KDFAQLAREYSDDAAAKKDGGSLGTFKRGEMLADLEKAILPLKPGEVGELVSTPSGLHIVKLDERSSGKVKPFETVKADI
SDLLYRQKQDSRFTSWMKELRTKASIEIKDGTGLI

Sequences:

>Translated_355_residues
MNHLRLLSLASLLSISLLGGCASTPDVITDTAKQQPPTLTVPKLAPLPAGAKRINGVAAIVNDDIITFREVLRESQAVIQ
DAQKKGLVDDTARHNLRVMVLDRLIEKLLTEQKIKELGIKIGDDEIRQAIDDVKRQNNNMTQSQLEAALKSQGYTFAQYE
VQLREQLERLRLVSMEVRSKIYVSEKEAEEYYQSHLSSYAEEETFKASHIFIKVDEKAPADQIQQAMNKALKVLFEARQG
KDFAQLAREYSDDAAAKKDGGSLGTFKRGEMLADLEKAILPLKPGEVGELVSTPSGLHIVKLDERSSGKVKPFETVKADI
SDLLYRQKQDSRFTSWMKELRTKASIEIKDGTGLI
>Mature_355_residues
MNHLRLLSLASLLSISLLGGCASTPDVITDTAKQQPPTLTVPKLAPLPAGAKRINGVAAIVNDDIITFREVLRESQAVIQ
DAQKKGLVDDTARHNLRVMVLDRLIEKLLTEQKIKELGIKIGDDEIRQAIDDVKRQNNNMTQSQLEAALKSQGYTFAQYE
VQLREQLERLRLVSMEVRSKIYVSEKEAEEYYQSHLSSYAEEETFKASHIFIKVDEKAPADQIQQAMNKALKVLFEARQG
KDFAQLAREYSDDAAAKKDGGSLGTFKRGEMLADLEKAILPLKPGEVGELVSTPSGLHIVKLDERSSGKVKPFETVKADI
SDLLYRQKQDSRFTSWMKELRTKASIEIKDGTGLI

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=209, Percent_Identity=29.1866028708134, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786645, Length=335, Percent_Identity=25.0746268656716, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 39652; Mature: 39652

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHLRLLSLASLLSISLLGGCASTPDVITDTAKQQPPTLTVPKLAPLPAGAKRINGVAAI
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEE
VNDDIITFREVLRESQAVIQDAQKKGLVDDTARHNLRVMVLDRLIEKLLTEQKIKELGIK
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
IGDDEIRQAIDDVKRQNNNMTQSQLEAALKSQGYTFAQYEVQLREQLERLRLVSMEVRSK
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
IYVSEKEAEEYYQSHLSSYAEEETFKASHIFIKVDEKAPADQIQQAMNKALKVLFEARQG
HHCCHHHHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
KDFAQLAREYSDDAAAKKDGGSLGTFKRGEMLADLEKAILPLKPGEVGELVSTPSGLHIV
CHHHHHHHHHCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEE
KLDERSSGKVKPFETVKADISDLLYRQKQDSRFTSWMKELRTKASIEIKDGTGLI
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEECCCCCCC
>Mature Secondary Structure
MNHLRLLSLASLLSISLLGGCASTPDVITDTAKQQPPTLTVPKLAPLPAGAKRINGVAAI
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEE
VNDDIITFREVLRESQAVIQDAQKKGLVDDTARHNLRVMVLDRLIEKLLTEQKIKELGIK
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
IGDDEIRQAIDDVKRQNNNMTQSQLEAALKSQGYTFAQYEVQLREQLERLRLVSMEVRSK
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
IYVSEKEAEEYYQSHLSSYAEEETFKASHIFIKVDEKAPADQIQQAMNKALKVLFEARQG
HHCCHHHHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
KDFAQLAREYSDDAAAKKDGGSLGTFKRGEMLADLEKAILPLKPGEVGELVSTPSGLHIV
CHHHHHHHHHCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEE
KLDERSSGKVKPFETVKADISDLLYRQKQDSRFTSWMKELRTKASIEIKDGTGLI
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]