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The map label for this gene is murG

Identifier: 189423739

GI number: 189423739

Start: 676989

End: 678134

Strand: Reverse

Name: murG

Synonym: Glov_0670

Alternate gene names: 189423739

Gene position: 678134-676989 (Counterclockwise)

Preceding gene: 189423740

Following gene: 189423738

Centisome position: 17.31

GC content: 58.29

Gene sequence:

>1146_bases
ATGAAACTGATTGTAGCCGGTGGCGGCACTGGCGGACACCTTTTTCCCGGCATTGCAGTGGCGGAAGAGTTTCTGTCGCG
GGATCCCGCCAACCAGGTGCTGTTTGTCGGATCAGAGCGGGGCATCGAGGCACGGGCCATCCCACGTCTTGGCTATCAGC
TGGAGTTGATCTCGGCCGCCGGAATTCGCGGCAAAGGCAGCCTGGCCAAGCTGAAAGGGGCGGCCATGATGATCTATGGC
TACGCCCAGTCCCGTAAAATCCTGCATCGTTTTCAACCGGATCTGGTGCTGGGGGTAGGCGGGTATGCCTCTCTGCCGAT
GGTAATGGCAGCGCGGGGGATGGAGATTCCACGCTATATCCATGAACAGAACGCCCTGCCCGGCATGTCCAACAAGGTCC
TGTCCCGGGTTGCCAACAAGGTCTTTATCTCTCTGGAAGAGTCGGCAAAGTTCTTTCCAAAGGACTGCACGCTGCTGACC
GGCAACCCGCTCAGAAAACAGATCCTTGAAATGCTGACACAGACAGAAACAGAAAATCCTCCCTCAATCCCCCCTTTGCT
AAAGGGGGGAAGCGAGCCGTGCGAGCAGAGGGGATTTAACCTCTTCATCTTTGGGGGCAGCCAAGGTGCCCATGCCCTGA
ATGTAGCGCTCCCCCAGGCTGTGGCACAGTTGAGTCCCAAACAGCAGAGGCTGATAAAGATCATCCACCAGACCGGTGAG
GCAGACCTGCAGCAGGTCCAGGCAGCCTATCAGGCAAACGGCCTTGAGGCTGATGTCCGCCCCTTTATTGACGACATGGC
AACCGCCTACCGGCAGGCCGATCTGATCATCTGCCGCGCAGGGGCCACCACCATTGCCGAGGTGACGGCACTGGGCAAGG
CCTGCCTGTTTGTGCCGTTTCCCCATGCCACTGATGACCATCAACGCAAGAACGCCGAGGCCCTGCTGAAAAAAGGGGCC
TGTGAGATGCTGGTGGAACAGGAGATCGGCGGCAAAGGGTTGTCCGAGGCCATTGCCAGGCTGATGGAGAACCGCGACGC
ACTGAAACTGATTGGTGAAAATGCCGCTGCCCTGGCCCGGCTGGATGCAGCCAGGGTTATTGTTGACCAGATGCTGGAAG
GGGTACAGCCATGTACGGAAACATAG

Upstream 100 bases:

>100_bases
ACGGCGGCAGCTCGTTATTGATCAGTCTGTTTGCCGTGGGGATTCTGTTGAACATCTCAGCCGGGCTGAAGCTGGCCCCG
CTGACCGGGAAGGACGCAAA

Downstream 100 bases:

>100_bases
AAAAGATCCACTTTGTAGGTATTGGCGGCATCGGCATGAGCGGTATTGCCGAAGTGCTGCTGAACCTGGGGTACCAGGTA
TCCGGTTCCGACCTGCGGGA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKLIVAGGGTGGHLFPGIAVAEEFLSRDPANQVLFVGSERGIEARAIPRLGYQLELISAAGIRGKGSLAKLKGAAMMIYG
YAQSRKILHRFQPDLVLGVGGYASLPMVMAARGMEIPRYIHEQNALPGMSNKVLSRVANKVFISLEESAKFFPKDCTLLT
GNPLRKQILEMLTQTETENPPSIPPLLKGGSEPCEQRGFNLFIFGGSQGAHALNVALPQAVAQLSPKQQRLIKIIHQTGE
ADLQQVQAAYQANGLEADVRPFIDDMATAYRQADLIICRAGATTIAEVTALGKACLFVPFPHATDDHQRKNAEALLKKGA
CEMLVEQEIGGKGLSEAIARLMENRDALKLIGENAAALARLDAARVIVDQMLEGVQPCTET

Sequences:

>Translated_381_residues
MKLIVAGGGTGGHLFPGIAVAEEFLSRDPANQVLFVGSERGIEARAIPRLGYQLELISAAGIRGKGSLAKLKGAAMMIYG
YAQSRKILHRFQPDLVLGVGGYASLPMVMAARGMEIPRYIHEQNALPGMSNKVLSRVANKVFISLEESAKFFPKDCTLLT
GNPLRKQILEMLTQTETENPPSIPPLLKGGSEPCEQRGFNLFIFGGSQGAHALNVALPQAVAQLSPKQQRLIKIIHQTGE
ADLQQVQAAYQANGLEADVRPFIDDMATAYRQADLIICRAGATTIAEVTALGKACLFVPFPHATDDHQRKNAEALLKKGA
CEMLVEQEIGGKGLSEAIARLMENRDALKLIGENAAALARLDAARVIVDQMLEGVQPCTET
>Mature_381_residues
MKLIVAGGGTGGHLFPGIAVAEEFLSRDPANQVLFVGSERGIEARAIPRLGYQLELISAAGIRGKGSLAKLKGAAMMIYG
YAQSRKILHRFQPDLVLGVGGYASLPMVMAARGMEIPRYIHEQNALPGMSNKVLSRVANKVFISLEESAKFFPKDCTLLT
GNPLRKQILEMLTQTETENPPSIPPLLKGGSEPCEQRGFNLFIFGGSQGAHALNVALPQAVAQLSPKQQRLIKIIHQTGE
ADLQQVQAAYQANGLEADVRPFIDDMATAYRQADLIICRAGATTIAEVTALGKACLFVPFPHATDDHQRKNAEALLKKGA
CEMLVEQEIGGKGLSEAIARLMENRDALKLIGENAAALARLDAARVIVDQMLEGVQPCTET

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=371, Percent_Identity=34.7708894878706, Blast_Score=209, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_GEOLS (B3E3Y2)

Other databases:

- EMBL:   CP001089
- RefSeq:   YP_001950916.1
- ProteinModelPortal:   B3E3Y2
- SMR:   B3E3Y2
- GeneID:   6369085
- GenomeReviews:   CP001089_GR
- KEGG:   glo:Glov_0670
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 40990; Mature: 40990

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIVAGGGTGGHLFPGIAVAEEFLSRDPANQVLFVGSERGIEARAIPRLGYQLELISAA
CEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHCCCCCCCEEEEEECC
GIRGKGSLAKLKGAAMMIYGYAQSRKILHRFQPDLVLGVGGYASLPMVMAARGMEIPRYI
CCCCCCCHHHHCCCEEEEEECHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCCHHHH
HEQNALPGMSNKVLSRVANKVFISLEESAKFFPKDCTLLTGNPLRKQILEMLTQTETENP
HHCCCCCCCHHHHHHHHHHHHEEEEHHHCCCCCCCCEEECCCHHHHHHHHHHHHCCCCCC
PSIPPLLKGGSEPCEQRGFNLFIFGGSQGAHALNVALPQAVAQLSPKQQRLIKIIHQTGE
CCCCHHHCCCCCCHHHCCCEEEEEECCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHCCH
ADLQQVQAAYQANGLEADVRPFIDDMATAYRQADLIICRAGATTIAEVTALGKACLFVPF
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCEEEEEEC
PHATDDHQRKNAEALLKKGACEMLVEQEIGGKGLSEAIARLMENRDALKLIGENAAALAR
CCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCCHHHHHH
LDAARVIVDQMLEGVQPCTET
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKLIVAGGGTGGHLFPGIAVAEEFLSRDPANQVLFVGSERGIEARAIPRLGYQLELISAA
CEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHCCCCCCCEEEEEECC
GIRGKGSLAKLKGAAMMIYGYAQSRKILHRFQPDLVLGVGGYASLPMVMAARGMEIPRYI
CCCCCCCHHHHCCCEEEEEECHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCCHHHH
HEQNALPGMSNKVLSRVANKVFISLEESAKFFPKDCTLLTGNPLRKQILEMLTQTETENP
HHCCCCCCCHHHHHHHHHHHHEEEEHHHCCCCCCCCEEECCCHHHHHHHHHHHHCCCCCC
PSIPPLLKGGSEPCEQRGFNLFIFGGSQGAHALNVALPQAVAQLSPKQQRLIKIIHQTGE
CCCCHHHCCCCCCHHHCCCEEEEEECCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHCCH
ADLQQVQAAYQANGLEADVRPFIDDMATAYRQADLIICRAGATTIAEVTALGKACLFVPF
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCEEEEEEC
PHATDDHQRKNAEALLKKGACEMLVEQEIGGKGLSEAIARLMENRDALKLIGENAAALAR
CCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCCHHHHHH
LDAARVIVDQMLEGVQPCTET
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA