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The map label for this gene is acuC [H]

Identifier: 189423588

GI number: 189423588

Start: 488712

End: 489863

Strand: Reverse

Name: acuC [H]

Synonym: Glov_0517

Alternate gene names: 189423588

Gene position: 489863-488712 (Counterclockwise)

Preceding gene: 189423589

Following gene: 189423587

Centisome position: 12.5

GC content: 61.46

Gene sequence:

>1152_bases
GTGCCACGTACCGCCCTCGTCTATTCATCCCGTTTTGAACAGTTCAGCTACGGCAGTCAGCACCCGTTTCAGCTGCACCG
TTACGGCCTGGCACTGGAGCTGCTGGAGGCCTATGGCCTGCTTGACCTGCCCGGCATGGAACGCCGTGACTGCACTCCGG
TGACCGACAAGCAGATCCTCAGCTTTCATACCCCGGCCTATCTGCAGCGTCTGAAAGAGTTCAGCGCCTCGGATGACCCC
CGGGCCGACTTCATGTTCGGCCTGGGTGATGCTGATTGTCCGGTCTTCAAAGGGCTCTACGACTATGCCGCCCTGGGGGC
AGGCGCCACACTGGAGGCCTGCCGCCTGATCGAGGAAGAGCGCTTTGACAGCGTACTGTCTCTGGCCGGCGGCTGGCACC
ATGGCCACCCTGCCAGGGCTTCAGGATTCTGCTACCTGAATGATGCAGTGATTGCCATCAACTGGCTGCGGGAACGGGGA
CGCCGGGTGGCCTACCTTGATCTGGATGCCCACCACGGTGACGGTGTCCAGGAGGGGTTCTACGCGGATGATCAGGTGCT
GACCATCTCACTGCATGAAAGCGGGGTCTACTTCTTTCCCGGCACCGGCTTTGAAGATGAGACCGGCATCGAGCGCGGAC
AGGGGTACAGTGTCAACCTGCCGCTCCTGGCCCATACCGATGATCCGCTCTACATGCGGGCCTTCGATGAGGTGGTCTAC
CCCCTGCTGGCGGCCTTTAACCCGGATATTATCGTGGCTCAGATCGGGGCTGATGCCTTCCGCACCGATCCGCTGACCAG
ACTGGAGATTACCACCCACAGCTATGCCTACATCATGCGCAAGCTGCAGGCCCTGCAGATCCCCTGGGTGGCGCTGGGGG
GGGGCGGCTATGACCTGATGAACACCGCCAGGGCCTGGACCATCGCCTGGGGCGCCATGAACAAGGTGGCACTGCCACCT
CGGTTGCCGGCTGCCTTTGTAAAAAAAATCCGCCAGCAGGGCTACCCGCACACCATGCTGCTGGATGCCCTGCACTGGGC
TGACGAGCATGACCGCGGCCTGGCGCTGGATGCCCTGGAACGCAGCATCAACGTCATCAAGAAGCAGATCTTCCCGGTGA
TTATCGGTGGAGAACTGGCGGTACTGCTCTGA

Upstream 100 bases:

>100_bases
AAAAACAGCAACCCCACTCAACCGGCGGCAACCAGATCAGGCAGCAGCTCTTCTCAAACCCGCGCCGATCTGCTGATTTC
AGCCTTTGCCTGATCCCACC

Downstream 100 bases:

>100_bases
TGCCGAAGCTGCCGGGAAACAGCCCGATGCTTGGCCGGCATGGCCACGCGCTGACCTCACTGGCGGCCATCAACCGGCTG
GATACACCGGAAAAAGAAGC

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MPRTALVYSSRFEQFSYGSQHPFQLHRYGLALELLEAYGLLDLPGMERRDCTPVTDKQILSFHTPAYLQRLKEFSASDDP
RADFMFGLGDADCPVFKGLYDYAALGAGATLEACRLIEEERFDSVLSLAGGWHHGHPARASGFCYLNDAVIAINWLRERG
RRVAYLDLDAHHGDGVQEGFYADDQVLTISLHESGVYFFPGTGFEDETGIERGQGYSVNLPLLAHTDDPLYMRAFDEVVY
PLLAAFNPDIIVAQIGADAFRTDPLTRLEITTHSYAYIMRKLQALQIPWVALGGGGYDLMNTARAWTIAWGAMNKVALPP
RLPAAFVKKIRQQGYPHTMLLDALHWADEHDRGLALDALERSINVIKKQIFPVIIGGELAVLL

Sequences:

>Translated_383_residues
MPRTALVYSSRFEQFSYGSQHPFQLHRYGLALELLEAYGLLDLPGMERRDCTPVTDKQILSFHTPAYLQRLKEFSASDDP
RADFMFGLGDADCPVFKGLYDYAALGAGATLEACRLIEEERFDSVLSLAGGWHHGHPARASGFCYLNDAVIAINWLRERG
RRVAYLDLDAHHGDGVQEGFYADDQVLTISLHESGVYFFPGTGFEDETGIERGQGYSVNLPLLAHTDDPLYMRAFDEVVY
PLLAAFNPDIIVAQIGADAFRTDPLTRLEITTHSYAYIMRKLQALQIPWVALGGGGYDLMNTARAWTIAWGAMNKVALPP
RLPAAFVKKIRQQGYPHTMLLDALHWADEHDRGLALDALERSINVIKKQIFPVIIGGELAVLL
>Mature_382_residues
PRTALVYSSRFEQFSYGSQHPFQLHRYGLALELLEAYGLLDLPGMERRDCTPVTDKQILSFHTPAYLQRLKEFSASDDPR
ADFMFGLGDADCPVFKGLYDYAALGAGATLEACRLIEEERFDSVLSLAGGWHHGHPARASGFCYLNDAVIAINWLRERGR
RVAYLDLDAHHGDGVQEGFYADDQVLTISLHESGVYFFPGTGFEDETGIERGQGYSVNLPLLAHTDDPLYMRAFDEVVYP
LLAAFNPDIIVAQIGADAFRTDPLTRLEITTHSYAYIMRKLQALQIPWVALGGGGYDLMNTARAWTIAWGAMNKVALPPR
LPAAFVKKIRQQGYPHTMLLDALHWADEHDRGLALDALERSINVIKKQIFPVIIGGELAVLL

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI8923769, Length=301, Percent_Identity=38.2059800664452, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI13128862, Length=327, Percent_Identity=36.697247706422, Blast_Score=208, Evalue=6e-54,
Organism=Homo sapiens, GI13128860, Length=324, Percent_Identity=33.9506172839506, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI293336691, Length=324, Percent_Identity=33.641975308642, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI262073088, Length=185, Percent_Identity=41.0810810810811, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI262073092, Length=211, Percent_Identity=40.2843601895735, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI17158039, Length=242, Percent_Identity=31.8181818181818, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI30795204, Length=242, Percent_Identity=31.8181818181818, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI30795202, Length=242, Percent_Identity=31.8181818181818, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI153085395, Length=191, Percent_Identity=32.9842931937173, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI148539870, Length=196, Percent_Identity=34.6938775510204, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI169234807, Length=196, Percent_Identity=34.6938775510204, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI62750347, Length=207, Percent_Identity=34.2995169082126, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI62750349, Length=207, Percent_Identity=34.2995169082126, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI13128864, Length=329, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI20070354, Length=292, Percent_Identity=28.0821917808219, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI217272877, Length=316, Percent_Identity=26.5822784810127, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI209862883, Length=292, Percent_Identity=26.027397260274, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17508561, Length=309, Percent_Identity=34.9514563106796, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17534739, Length=330, Percent_Identity=34.5454545454545, Blast_Score=204, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI17561978, Length=326, Percent_Identity=35.2760736196319, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17540334, Length=338, Percent_Identity=26.3313609467456, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI193206283, Length=338, Percent_Identity=26.3313609467456, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17540332, Length=338, Percent_Identity=26.3313609467456, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI193209491, Length=213, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17537347, Length=311, Percent_Identity=27.0096463022508, Blast_Score=101, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6321244, Length=326, Percent_Identity=36.8098159509202, Blast_Score=231, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6323999, Length=324, Percent_Identity=36.7283950617284, Blast_Score=229, Evalue=7e-61,
Organism=Saccharomyces cerevisiae, GI6324307, Length=323, Percent_Identity=33.1269349845201, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6325325, Length=233, Percent_Identity=32.618025751073, Blast_Score=119, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24644244, Length=330, Percent_Identity=35.7575757575758, Blast_Score=214, Evalue=8e-56,
Organism=Drosophila melanogaster, GI24657891, Length=324, Percent_Identity=34.2592592592593, Blast_Score=201, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24641720, Length=178, Percent_Identity=37.0786516853933, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281360799, Length=178, Percent_Identity=37.0786516853933, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281360801, Length=178, Percent_Identity=37.0786516853933, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281360899, Length=318, Percent_Identity=27.9874213836478, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24642142, Length=318, Percent_Identity=27.9874213836478, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24642146, Length=318, Percent_Identity=27.9874213836478, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24642144, Length=318, Percent_Identity=27.9874213836478, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24649807, Length=180, Percent_Identity=31.1111111111111, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 42750; Mature: 42619

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRTALVYSSRFEQFSYGSQHPFQLHRYGLALELLEAYGLLDLPGMERRDCTPVTDKQIL
CCCCEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
SFHTPAYLQRLKEFSASDDPRADFMFGLGDADCPVFKGLYDYAALGAGATLEACRLIEEE
HCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
RFDSVLSLAGGWHHGHPARASGFCYLNDAVIAINWLRERGRRVAYLDLDAHHGDGVQEGF
HHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEHHHHHHCCEEEEEEEECCCCCCCCCCC
YADDQVLTISLHESGVYFFPGTGFEDETGIERGQGYSVNLPLLAHTDDPLYMRAFDEVVY
CCCCEEEEEEEECCCEEEECCCCCCCCCCCCCCCCEEEECCEEEECCCCHHHHHHHHHHH
PLLAAFNPDIIVAQIGADAFRTDPLTRLEITTHSYAYIMRKLQALQIPWVALGGGGYDLM
HHHHHCCCCEEEEEECCCHHCCCCCEEEEEECHHHHHHHHHHHHHCCCEEEECCCCHHHH
NTARAWTIAWGAMNKVALPPRLPAAFVKKIRQQGYPHTMLLDALHWADEHDRGLALDALE
HCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHH
RSINVIKKQIFPVIIGGELAVLL
HHHHHHHHHHCCEEECCEEEEEC
>Mature Secondary Structure 
PRTALVYSSRFEQFSYGSQHPFQLHRYGLALELLEAYGLLDLPGMERRDCTPVTDKQIL
CCCEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
SFHTPAYLQRLKEFSASDDPRADFMFGLGDADCPVFKGLYDYAALGAGATLEACRLIEEE
HCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
RFDSVLSLAGGWHHGHPARASGFCYLNDAVIAINWLRERGRRVAYLDLDAHHGDGVQEGF
HHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEHHHHHHCCEEEEEEEECCCCCCCCCCC
YADDQVLTISLHESGVYFFPGTGFEDETGIERGQGYSVNLPLLAHTDDPLYMRAFDEVVY
CCCCEEEEEEEECCCEEEECCCCCCCCCCCCCCCCEEEECCEEEECCCCHHHHHHHHHHH
PLLAAFNPDIIVAQIGADAFRTDPLTRLEITTHSYAYIMRKLQALQIPWVALGGGGYDLM
HHHHHCCCCEEEEEECCCHHCCCCCEEEEEECHHHHHHHHHHHHHCCCEEEECCCCHHHH
NTARAWTIAWGAMNKVALPPRLPAAFVKKIRQQGYPHTMLLDALHWADEHDRGLALDALE
HCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHH
RSINVIKKQIFPVIIGGELAVLL
HHHHHHHHHHCCEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]