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The map label for this gene is cat1 [H]

Identifier: 189423416

GI number: 189423416

Start: 315525

End: 317120

Strand: Reverse

Name: cat1 [H]

Synonym: Glov_0345

Alternate gene names: 189423416

Gene position: 317120-315525 (Counterclockwise)

Preceding gene: 189423417

Following gene: 189423414

Centisome position: 8.09

GC content: 57.52

Gene sequence:

>1596_bases
ATGTCAGAGTACGGAACTTTGCAAGACCGCGTTCAGTGCAAATCACTGCTGGACAAGGTAAAGACCCCAGAGCAGTGCAT
TGAGTACTTCAAAGACGGCATGAACCTTGGCTGGTCAGGCTTTACTCCGGCCGGATACCCCAAAGTGGTACCTATCGCCC
TGGCTGAGCATGTTGAAAAAAACAACCTGCAAGGCAAACTGAAATTCAACCTGTTCATCGGCGCTTCGGTCGGTGCAGAG
ACTGAAAACCGCTGGGCAATCAACGACATGATCGACCGCCGCTGGCCGTATCAGACCGGCAAGGACATTGCCGCCGGTAT
CAACGCCGGCCGCATCCGGATGGGCGACAAGCACCTCTCCCTGTTTGCCCAGGACCTGGGCTACGGCTTCTACACCAAGG
ATACCGAGACCGGTAAACTGGACCTGGCCATCATCGAGGTTTCCGAGATCCTGGAAGACGGCAGCCTGGTACCGACCTCT
TCCTGCGGCGTTATCCCTGAGATCCTGATGATCTGCGACAAGATCATCATCGAGGTAAACACCGGACAGCCTTCCTTCAA
AGGCATCCATGACCTGTTGACCCCCCTGACCCCGCCGAACCGTCAGGTATTCAACATTACCCGTGCCGACTCACGTATCG
GCTCCATCTCCATCCCCTGCGATCCAAGCAAGGTGATTGCAGTGGTTGAGTCCAAGCTGCGTGACCAGGGCCGTGCCTTT
GCCGAGCAGGACGACACCTCCGAGGCGATTGCAAACCACATCATCGACTTCTTCACCCATGAAGTGAAGGCTGGCCGTCT
GCCCAAGAACCTGCTGCCGATCCAATCCGGCGTGGGCTCCATCGCCAACGCTGTTATCGGTGGCCTGGCAAAAGGTCCTT
TCAAGAACCTGACCGTCTACACCGAAGTACTGCAGGACACCATGCTTGACCTGTTTGACTCCGGCAAACTGGACGCCGCT
TCTTCCTGCTCCCTGTCACTGTCCGCTGATCCGGGCTTCCCCCGTTTCTTTGCCAACATGGACAAGTATTTCGACAAGAT
CACCCTGCGTCCGCTCTCCATCTCCAACGCTCCGGAGCCGATCCGCCGTCTGGGTTGTATCGCCATGAACACCCCGGTTG
AGATCGACATCTATGCACACGCCAACTCCACCCTGGTTGGCGGCACCCGGATGATCAACGGCTTGGGCGGTTCCGGTGAC
TTCCTGCGTAACGGCTTCCTGAAGATGATGCATACCCCTTCCAGCCGCCCAAGCAAGACCGACCCGACCGGTATCTCCTG
CGTGGTACCACACTGCTCACACATCGACCACACCGAGCACGACCTGGACTGCGTCATCACCGAGCAGGGTCTGGCCGACC
TGCGTGGTGTAGCTCCGAAAGAGCGCGCCCGTCGCATCATCGAGAAGTGCGCCCACCCGGACTACAAGGCTCAGTTGACC
GAGTACCTGAACATTGCCGAGGCAGACTGCCTCAAGCGTAAGGTTGGTCACGAGCCGCAACTGTGGGATCGCGCCTTCAA
GATGCACCTCAACCTTGAGAAGAACGGCACCATGAAACTCAAGAACTGGGACGTCAAGATCGACCTCTGCGAGTAG

Upstream 100 bases:

>100_bases
TTCAACACTCTGTTTTTGCGCATGTTTTTTTAGCTTTATTCGCCGTTGCGTGTATGCTTCGACGCTGTGTAGACACAAAA
ACAAAACAGGAGGTAGTAAG

Downstream 100 bases:

>100_bases
TCGAATTCTGTTACGTAGCGCACACCCCGCCGGGTCACCGGCGGGGTTTTTTATTTCCAGGAGACCTTTTTCACCATCAA
ATTCATTCTTGCGCTTAGGT

Product: acetyl-CoA hydrolase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MSEYGTLQDRVQCKSLLDKVKTPEQCIEYFKDGMNLGWSGFTPAGYPKVVPIALAEHVEKNNLQGKLKFNLFIGASVGAE
TENRWAINDMIDRRWPYQTGKDIAAGINAGRIRMGDKHLSLFAQDLGYGFYTKDTETGKLDLAIIEVSEILEDGSLVPTS
SCGVIPEILMICDKIIIEVNTGQPSFKGIHDLLTPLTPPNRQVFNITRADSRIGSISIPCDPSKVIAVVESKLRDQGRAF
AEQDDTSEAIANHIIDFFTHEVKAGRLPKNLLPIQSGVGSIANAVIGGLAKGPFKNLTVYTEVLQDTMLDLFDSGKLDAA
SSCSLSLSADPGFPRFFANMDKYFDKITLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGD
FLRNGFLKMMHTPSSRPSKTDPTGISCVVPHCSHIDHTEHDLDCVITEQGLADLRGVAPKERARRIIEKCAHPDYKAQLT
EYLNIAEADCLKRKVGHEPQLWDRAFKMHLNLEKNGTMKLKNWDVKIDLCE

Sequences:

>Translated_531_residues
MSEYGTLQDRVQCKSLLDKVKTPEQCIEYFKDGMNLGWSGFTPAGYPKVVPIALAEHVEKNNLQGKLKFNLFIGASVGAE
TENRWAINDMIDRRWPYQTGKDIAAGINAGRIRMGDKHLSLFAQDLGYGFYTKDTETGKLDLAIIEVSEILEDGSLVPTS
SCGVIPEILMICDKIIIEVNTGQPSFKGIHDLLTPLTPPNRQVFNITRADSRIGSISIPCDPSKVIAVVESKLRDQGRAF
AEQDDTSEAIANHIIDFFTHEVKAGRLPKNLLPIQSGVGSIANAVIGGLAKGPFKNLTVYTEVLQDTMLDLFDSGKLDAA
SSCSLSLSADPGFPRFFANMDKYFDKITLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGD
FLRNGFLKMMHTPSSRPSKTDPTGISCVVPHCSHIDHTEHDLDCVITEQGLADLRGVAPKERARRIIEKCAHPDYKAQLT
EYLNIAEADCLKRKVGHEPQLWDRAFKMHLNLEKNGTMKLKNWDVKIDLCE
>Mature_530_residues
SEYGTLQDRVQCKSLLDKVKTPEQCIEYFKDGMNLGWSGFTPAGYPKVVPIALAEHVEKNNLQGKLKFNLFIGASVGAET
ENRWAINDMIDRRWPYQTGKDIAAGINAGRIRMGDKHLSLFAQDLGYGFYTKDTETGKLDLAIIEVSEILEDGSLVPTSS
CGVIPEILMICDKIIIEVNTGQPSFKGIHDLLTPLTPPNRQVFNITRADSRIGSISIPCDPSKVIAVVESKLRDQGRAFA
EQDDTSEAIANHIIDFFTHEVKAGRLPKNLLPIQSGVGSIANAVIGGLAKGPFKNLTVYTEVLQDTMLDLFDSGKLDAAS
SCSLSLSADPGFPRFFANMDKYFDKITLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDF
LRNGFLKMMHTPSSRPSKTDPTGISCVVPHCSHIDHTEHDLDCVITEQGLADLRGVAPKERARRIIEKCAHPDYKAQLTE
YLNIAEADCLKRKVGHEPQLWDRAFKMHLNLEKNGTMKLKNWDVKIDLCE

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=501, Percent_Identity=40.1197604790419, Blast_Score=369, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6319456, Length=525, Percent_Identity=58.2857142857143, Blast_Score=619, Evalue=1e-178,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 58559; Mature: 58428

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYGTLQDRVQCKSLLDKVKTPEQCIEYFKDGMNLGWSGFTPAGYPKVVPIALAEHVEK
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHH
NNLQGKLKFNLFIGASVGAETENRWAINDMIDRRWPYQTGKDIAAGINAGRIRMGDKHLS
CCCCEEEEEEEEEECCCCCCCCCCEEHHHHHHCCCCCCCCCHHHHCCCCCEEEECHHHHH
LFAQDLGYGFYTKDTETGKLDLAIIEVSEILEDGSLVPTSSCGVIPEILMICDKIIIEVN
HHHHHHCCCEEECCCCCCEEEEEEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHEEEEEE
TGQPSFKGIHDLLTPLTPPNRQVFNITRADSRIGSISIPCDPSKVIAVVESKLRDQGRAF
CCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHCCHH
AEQDDTSEAIANHIIDFFTHEVKAGRLPKNLLPIQSGVGSIANAVIGGLAKGPFKNLTVY
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHH
TEVLQDTMLDLFDSGKLDAASSCSLSLSADPGFPRFFANMDKYFDKITLRPLSISNAPEP
HHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHEEEEEECCCCCCHH
IRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDFLRNGFLKMMHTPSSRPSKT
HHHHCCEEECCCEEEEEEEECCCEEECCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
DPTGISCVVPHCSHIDHTEHDLDCVITEQGLADLRGVAPKERARRIIEKCAHPDYKAQLT
CCCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
EYLNIAEADCLKRKVGHEPQLWDRAFKMHLNLEKNGTMKLKNWDVKIDLCE
HHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCEEEEECCEEEEEECC
>Mature Secondary Structure 
SEYGTLQDRVQCKSLLDKVKTPEQCIEYFKDGMNLGWSGFTPAGYPKVVPIALAEHVEK
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHH
NNLQGKLKFNLFIGASVGAETENRWAINDMIDRRWPYQTGKDIAAGINAGRIRMGDKHLS
CCCCEEEEEEEEEECCCCCCCCCCEEHHHHHHCCCCCCCCCHHHHCCCCCEEEECHHHHH
LFAQDLGYGFYTKDTETGKLDLAIIEVSEILEDGSLVPTSSCGVIPEILMICDKIIIEVN
HHHHHHCCCEEECCCCCCEEEEEEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHEEEEEE
TGQPSFKGIHDLLTPLTPPNRQVFNITRADSRIGSISIPCDPSKVIAVVESKLRDQGRAF
CCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHCCHH
AEQDDTSEAIANHIIDFFTHEVKAGRLPKNLLPIQSGVGSIANAVIGGLAKGPFKNLTVY
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHH
TEVLQDTMLDLFDSGKLDAASSCSLSLSADPGFPRFFANMDKYFDKITLRPLSISNAPEP
HHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHEEEEEECCCCCCHH
IRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDFLRNGFLKMMHTPSSRPSKT
HHHHCCEEECCCEEEEEEEECCCEEECCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
DPTGISCVVPHCSHIDHTEHDLDCVITEQGLADLRGVAPKERARRIIEKCAHPDYKAQLT
CCCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
EYLNIAEADCLKRKVGHEPQLWDRAFKMHLNLEKNGTMKLKNWDVKIDLCE
HHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCEEEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]