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The map label for this gene is dctB [H]

Identifier: 189353885

GI number: 189353885

Start: 2193795

End: 2195678

Strand: Direct

Name: dctB [H]

Synonym: BMULJ_05137

Alternate gene names: 189353885

Gene position: 2193795-2195678 (Clockwise)

Preceding gene: 189353884

Following gene: 189353886

Centisome position: 88.7

GC content: 69.43

Gene sequence:

>1884_bases
ATGAGGGCGAACGTGCAGAAGAGCTTCAAGGGAATCCCGTGGTGGGGCTGGGCGTCGGCGGCCGTGCTGTATGTCGGCGT
CGCGGGCGCGGTCGTCGATTTCGCGTGGGAACGCGCGATCGACGCGCTCGAGGAAGCCGGCGCGCATCGGCTCGACCTGT
ACGCATCGAGCCTGAAGAGCGAGCTCGGCCGCTTCGAGATCCTGCCCGCACTGGTCGCGCGGCAGGACAGCGTGCGTGCG
TTGCTGAAGGCGTCGCCGCAACAGGCGCGTGACCTGCTGCATCCGGTCGACGTCTATCTCGAAGCCGTGAACCGCGACGC
AGGCAGCGGCGCGGTAGACGTAATCGATCTGCACGGCGACGTGATCGCCGCGAGCAACTGGAACGAGCCGGTCAGCTTCG
TCGGCACGAACGTGTCGTACCGGCCGTATTTCAAGGACGCGCTCGCGCGCGGCAGCGGCCGCTTCTTCGGGATCGGCACG
AACACCGGCGTGCTGGGCGTCTATTTCGCGAGCGCGGTGCGCGACGACGGCACGCCGATCGGCGTCGCGGCCGCGAAGAT
CAGCGTCGATCCGCTCGAATCTGCGTGGCGCGCGCCCGGTGTCGCGGCGATGGTCGTCGACGGCAACGGCGTCGTCGTCA
TCTCGACCGAGCCCGCATGGAAATTCACGGCGCTGCGCCCGATCACCGCGCAGCAGCAGCGCGACATCCAGGCGTCGCGC
CAGTATGCGGGCCGCACCGTCGACGCGCTGCCGTACCACCGCATCGGCGAGCACAGCGCGGCCGCGTGGTTCGGCACGTT
TTCCGATCCGCATCGCGCGGGCCGCACCGCGCGCTATCTCGTGATGTCGCGTCCCGCGCCGCAGGCCGGCGATTCGCTGA
TGGTGCTGCTCGACACCGCCGGCGCGCGCCGTCAGCAGCAGACGGCATTCGTGTTCGTGACGGGCGCGTTCCTGATCGTC
GCGCTGCTGGTCGGCTATGCGATCCAGCGGCGCCGGGCGATCGCCGCACGGCTGAGCGCGCAGGACGCGCTGCGCCGCGC
GAACGATCGGCTCGAGCTGACCGTCGCGCAGCGCACCGCGGCGCTCACCGAGGCGAACGAGCGGATGCAGCGCGAGATCG
TCGAGCGCGAACGCACCGAACAGCGGCTGCGCGATTCGCAGCAGGAAGTCGTGCACGCCGGCAAGCTCGCCGTGCTCGGA
CAGATGGCGGCCGGCCTCACGCACGAGCTGAACCAGCCGCTCGTCGCGATCCGCACGCTGTGCGACAACGCGCGCACGTT
CTTCGAGCGCGATCAACCCGCGCAGGCGTTTGCGAATCTCGAACGGATCGGCAAGCTCGTCGACGGGATGGCTGTGCTCA
CCGGTGAACTGAAGACGTTCGCGCGCAAGCCCGACGTGGAACGCGTCGCGGTGTCGCTGAACGAAGCCGTCGCGCATGCG
CGGCTGATCTACGATGCGCGGCTGCGCGACGAAGGCGTGCAGCTCGACGTGAACATCGCGCCCGGCACGACCGTGTCGGC
CGAATCGAGCCAGTTGCAGCAGGTGATCGTGAACCTGCTCGGCAACGCGCTCGATGCCGTTCACGACGCGCCGGTGCGCC
GCATCGCGATCGCCGCCGACGCGCCCGATGCGCACGGGCGCGTGCGCTTCACCGTGACGGATTCCGGCGCCGGCATCGCA
CCCGACGTGCTGCCGCACCTGTTCGAGCCGTTCGTCACGACGAAGCCGCGCGGCCAGGGCCTCGGGCTCGGGCTTGCGAT
CACGTCGCGGATCGTCGAAGGATTCGGCGCGAAGATCGCCGCGACGAACCGTGACGGCGGCGGTGCGCAGTTCACCATCG
AATTCGCGGCGGCCACGCCGCAAAGGACAGAGCATGGAAGATGA

Upstream 100 bases:

>100_bases
CGTTGAGGACGGCCGGTTGGACGGCCAGTTGGACGGCCAGTTGGACGGCCAGTTGGACGGCCGGTTGGACGGCCGATGCG
GCAACCGATTGCGGGCTTCG

Downstream 100 bases:

>100_bases
GATTCGCGTGCTGGTCGTCGAGGACGATGAAAACGTCCGGATCGGCGTCGAGCAGGCTGTTGCGCTCGCCGGGTTTCCTG
TGCAGGCGTTCGCGTCGGCA

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MRANVQKSFKGIPWWGWASAAVLYVGVAGAVVDFAWERAIDALEEAGAHRLDLYASSLKSELGRFEILPALVARQDSVRA
LLKASPQQARDLLHPVDVYLEAVNRDAGSGAVDVIDLHGDVIAASNWNEPVSFVGTNVSYRPYFKDALARGSGRFFGIGT
NTGVLGVYFASAVRDDGTPIGVAAAKISVDPLESAWRAPGVAAMVVDGNGVVVISTEPAWKFTALRPITAQQQRDIQASR
QYAGRTVDALPYHRIGEHSAAAWFGTFSDPHRAGRTARYLVMSRPAPQAGDSLMVLLDTAGARRQQQTAFVFVTGAFLIV
ALLVGYAIQRRRAIAARLSAQDALRRANDRLELTVAQRTAALTEANERMQREIVERERTEQRLRDSQQEVVHAGKLAVLG
QMAAGLTHELNQPLVAIRTLCDNARTFFERDQPAQAFANLERIGKLVDGMAVLTGELKTFARKPDVERVAVSLNEAVAHA
RLIYDARLRDEGVQLDVNIAPGTTVSAESSQLQQVIVNLLGNALDAVHDAPVRRIAIAADAPDAHGRVRFTVTDSGAGIA
PDVLPHLFEPFVTTKPRGQGLGLGLAITSRIVEGFGAKIAATNRDGGGAQFTIEFAAATPQRTEHGR

Sequences:

>Translated_627_residues
MRANVQKSFKGIPWWGWASAAVLYVGVAGAVVDFAWERAIDALEEAGAHRLDLYASSLKSELGRFEILPALVARQDSVRA
LLKASPQQARDLLHPVDVYLEAVNRDAGSGAVDVIDLHGDVIAASNWNEPVSFVGTNVSYRPYFKDALARGSGRFFGIGT
NTGVLGVYFASAVRDDGTPIGVAAAKISVDPLESAWRAPGVAAMVVDGNGVVVISTEPAWKFTALRPITAQQQRDIQASR
QYAGRTVDALPYHRIGEHSAAAWFGTFSDPHRAGRTARYLVMSRPAPQAGDSLMVLLDTAGARRQQQTAFVFVTGAFLIV
ALLVGYAIQRRRAIAARLSAQDALRRANDRLELTVAQRTAALTEANERMQREIVERERTEQRLRDSQQEVVHAGKLAVLG
QMAAGLTHELNQPLVAIRTLCDNARTFFERDQPAQAFANLERIGKLVDGMAVLTGELKTFARKPDVERVAVSLNEAVAHA
RLIYDARLRDEGVQLDVNIAPGTTVSAESSQLQQVIVNLLGNALDAVHDAPVRRIAIAADAPDAHGRVRFTVTDSGAGIA
PDVLPHLFEPFVTTKPRGQGLGLGLAITSRIVEGFGAKIAATNRDGGGAQFTIEFAAATPQRTEHGR
>Mature_627_residues
MRANVQKSFKGIPWWGWASAAVLYVGVAGAVVDFAWERAIDALEEAGAHRLDLYASSLKSELGRFEILPALVARQDSVRA
LLKASPQQARDLLHPVDVYLEAVNRDAGSGAVDVIDLHGDVIAASNWNEPVSFVGTNVSYRPYFKDALARGSGRFFGIGT
NTGVLGVYFASAVRDDGTPIGVAAAKISVDPLESAWRAPGVAAMVVDGNGVVVISTEPAWKFTALRPITAQQQRDIQASR
QYAGRTVDALPYHRIGEHSAAAWFGTFSDPHRAGRTARYLVMSRPAPQAGDSLMVLLDTAGARRQQQTAFVFVTGAFLIV
ALLVGYAIQRRRAIAARLSAQDALRRANDRLELTVAQRTAALTEANERMQREIVERERTEQRLRDSQQEVVHAGKLAVLG
QMAAGLTHELNQPLVAIRTLCDNARTFFERDQPAQAFANLERIGKLVDGMAVLTGELKTFARKPDVERVAVSLNEAVAHA
RLIYDARLRDEGVQLDVNIAPGTTVSAESSQLQQVIVNLLGNALDAVHDAPVRRIAIAADAPDAHGRVRFTVTDSGAGIA
PDVLPHLFEPFVTTKPRGQGLGLGLAITSRIVEGFGAKIAATNRDGGGAQFTIEFAAATPQRTEHGR

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=241, Percent_Identity=34.0248962655602, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=30, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787894, Length=228, Percent_Identity=28.0701754385965, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790861, Length=215, Percent_Identity=30.2325581395349, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=29.646017699115, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67599; Mature: 67599

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRANVQKSFKGIPWWGWASAAVLYVGVAGAVVDFAWERAIDALEEAGAHRLDLYASSLKS
CCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ELGRFEILPALVARQDSVRALLKASPQQARDLLHPVDVYLEAVNRDAGSGAVDVIDLHGD
HHCHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
VIAASNWNEPVSFVGTNVSYRPYFKDALARGSGRFFGIGTNTGVLGVYFASAVRDDGTPI
EEEECCCCCCHHHEECCCCCCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCCE
GVAAAKISVDPLESAWRAPGVAAMVVDGNGVVVISTEPAWKFTALRPITAQQQRDIQASR
EEEEEEEECCHHHHHHCCCCEEEEEECCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHH
QYAGRTVDALPYHRIGEHSAAAWFGTFSDPHRAGRTARYLVMSRPAPQAGDSLMVLLDTA
HHCCCCCCCCCCHHCCCCCCCEEECCCCCHHHCCCCEEEEEEECCCCCCCCCEEEEEECC
GARRQQQTAFVFVTGAFLIVALLVGYAIQRRRAIAARLSAQDALRRANDRLELTVAQRTA
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHH
ALTEANERMQREIVERERTEQRLRDSQQEVVHAGKLAVLGQMAAGLTHELNQPLVAIRTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
CDNARTFFERDQPAQAFANLERIGKLVDGMAVLTGELKTFARKPDVERVAVSLNEAVAHA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
RLIYDARLRDEGVQLDVNIAPGTTVSAESSQLQQVIVNLLGNALDAVHDAPVRRIAIAAD
HHHHHHHCCCCCCEEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
APDAHGRVRFTVTDSGAGIAPDVLPHLFEPFVTTKPRGQGLGLGLAITSRIVEGFGAKIA
CCCCCCEEEEEEECCCCCCCHHHHHHHHCCHHCCCCCCCCCEEHHHHHHHHHHHCCCEEE
ATNRDGGGAQFTIEFAAATPQRTEHGR
EECCCCCCEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MRANVQKSFKGIPWWGWASAAVLYVGVAGAVVDFAWERAIDALEEAGAHRLDLYASSLKS
CCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ELGRFEILPALVARQDSVRALLKASPQQARDLLHPVDVYLEAVNRDAGSGAVDVIDLHGD
HHCHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
VIAASNWNEPVSFVGTNVSYRPYFKDALARGSGRFFGIGTNTGVLGVYFASAVRDDGTPI
EEEECCCCCCHHHEECCCCCCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCCE
GVAAAKISVDPLESAWRAPGVAAMVVDGNGVVVISTEPAWKFTALRPITAQQQRDIQASR
EEEEEEEECCHHHHHHCCCCEEEEEECCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHH
QYAGRTVDALPYHRIGEHSAAAWFGTFSDPHRAGRTARYLVMSRPAPQAGDSLMVLLDTA
HHCCCCCCCCCCHHCCCCCCCEEECCCCCHHHCCCCEEEEEEECCCCCCCCCEEEEEECC
GARRQQQTAFVFVTGAFLIVALLVGYAIQRRRAIAARLSAQDALRRANDRLELTVAQRTA
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHH
ALTEANERMQREIVERERTEQRLRDSQQEVVHAGKLAVLGQMAAGLTHELNQPLVAIRTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
CDNARTFFERDQPAQAFANLERIGKLVDGMAVLTGELKTFARKPDVERVAVSLNEAVAHA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
RLIYDARLRDEGVQLDVNIAPGTTVSAESSQLQQVIVNLLGNALDAVHDAPVRRIAIAAD
HHHHHHHCCCCCCEEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
APDAHGRVRFTVTDSGAGIAPDVLPHLFEPFVTTKPRGQGLGLGLAITSRIVEGFGAKIA
CCCCCCEEEEEEECCCCCCCHHHHHHHHCCHHCCCCCCCCCEEHHHHHHHHHHHCCCEEE
ATNRDGGGAQFTIEFAAATPQRTEHGR
EECCCCCCEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]