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The map label for this gene is speB [H]

Identifier: 189353833

GI number: 189353833

Start: 2135775

End: 2136731

Strand: Direct

Name: speB [H]

Synonym: BMULJ_05080

Alternate gene names: 189353833

Gene position: 2135775-2136731 (Clockwise)

Preceding gene: 189353831

Following gene: 189353834

Centisome position: 86.36

GC content: 67.61

Gene sequence:

>957_bases
ATGAACGACCACACCCATTTCCAGCCGCTCGGCGGCAATGAAATGCCGCGCTGCGGCGGCATCGCGACGATGATGCGCCT
GCCGCACGTGGCGAGCGCCGCCGGCCTCGACGCCTGCTTCGTCGGCGTGCCGTTCGATCTCGGCACGTCGAACCGCACCG
GCGCACGCTTCGGCCCGCGCCAGATCCGTACCGAATCCGTGCTGCTGCGCCCGTACAACATGGCGACGCGCGCCGCGCCG
TTCGATTCGCTGCAGATCGCCGACATCGGCGACGTCGCGATCAATCCGTACAACCTGCACGATTCGATCGCGCGCATCGA
AGCCGCGTACGACGCGATCCTCGAGCACGACTGCAAGCCGATCACGCTCGGCGGCGATCATACGATCGCGCTGCCGATCC
TGCGCGCGATCCACCGCAAGCACGGCAAGGTCGCATTGATCCACGTCGATGCGCACGCCGACGTGAACGATACGATGATG
GGCGAAAAGATCGCGCACGGCACGCCGTTTCGCCGCGCGGTCGAGGAAGGCCTGCTGCACGGCGACAAGGTCACGCAGAT
CGGCCTGCGCGGCACCGGCTACGCAGCCGAAGACTTCGACTGGTGCCGCGAGCAGGGTTTCCGCGTCGTTCAGGCGGAAG
AATGCTGGAACAAGTCGCTCGCGCCGCTGATGGACGAAGTGCGCGAGCGTGTCGGCGACACGCCCGTCTACATCAGCTTC
GACATCGACGGCATCGATCCCGCCTACGCACCGGGCACCGGCACGCCCGAAATCGCGGGCCTCACGGTGCCGCAGGCGCT
CGAGATCATCCGCGGCGCGCGCGGGCTGAACATCGTCGGCTGCGATCTCGTCGAAGTCGCGCCGCCGTACGACCCGTTCG
GCACGACGGCACTGCTCGGCGCGAACCTCGCATACGAGCTGCTGTGCGTGCTGCCGGGCGTCGCGTACCGCGACTGA

Upstream 100 bases:

>100_bases
ACGTCGATATCTTCGCATTCTTCTTTAAGGCCGGAACGCGTACAACTGTGCGCCGAGCCGCGTCGAATGATACGGCAACC
CCACATTGGAAGAGCGCCCC

Downstream 100 bases:

>100_bases
CGCGCGCCACGACCATTCCCAATCAGAGGATTCATGAGGAGCCAGAAAAAGATGGAGACTTCCGTCAAGCAACCGAAGCG
GGCGGCGCTTGCGTCGTTCG

Product: agmatinase

Products: NA

Alternate protein names: GBase; D-arginase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MNDHTHFQPLGGNEMPRCGGIATMMRLPHVASAAGLDACFVGVPFDLGTSNRTGARFGPRQIRTESVLLRPYNMATRAAP
FDSLQIADIGDVAINPYNLHDSIARIEAAYDAILEHDCKPITLGGDHTIALPILRAIHRKHGKVALIHVDAHADVNDTMM
GEKIAHGTPFRRAVEEGLLHGDKVTQIGLRGTGYAAEDFDWCREQGFRVVQAEECWNKSLAPLMDEVRERVGDTPVYISF
DIDGIDPAYAPGTGTPEIAGLTVPQALEIIRGARGLNIVGCDLVEVAPPYDPFGTTALLGANLAYELLCVLPGVAYRD

Sequences:

>Translated_318_residues
MNDHTHFQPLGGNEMPRCGGIATMMRLPHVASAAGLDACFVGVPFDLGTSNRTGARFGPRQIRTESVLLRPYNMATRAAP
FDSLQIADIGDVAINPYNLHDSIARIEAAYDAILEHDCKPITLGGDHTIALPILRAIHRKHGKVALIHVDAHADVNDTMM
GEKIAHGTPFRRAVEEGLLHGDKVTQIGLRGTGYAAEDFDWCREQGFRVVQAEECWNKSLAPLMDEVRERVGDTPVYISF
DIDGIDPAYAPGTGTPEIAGLTVPQALEIIRGARGLNIVGCDLVEVAPPYDPFGTTALLGANLAYELLCVLPGVAYRD
>Mature_318_residues
MNDHTHFQPLGGNEMPRCGGIATMMRLPHVASAAGLDACFVGVPFDLGTSNRTGARFGPRQIRTESVLLRPYNMATRAAP
FDSLQIADIGDVAINPYNLHDSIARIEAAYDAILEHDCKPITLGGDHTIALPILRAIHRKHGKVALIHVDAHADVNDTMM
GEKIAHGTPFRRAVEEGLLHGDKVTQIGLRGTGYAAEDFDWCREQGFRVVQAEECWNKSLAPLMDEVRERVGDTPVYISF
DIDGIDPAYAPGTGTPEIAGLTVPQALEIIRGARGLNIVGCDLVEVAPPYDPFGTTALLGANLAYELLCVLPGVAYRD

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=313, Percent_Identity=60.3833865814696, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI10947139, Length=305, Percent_Identity=24.2622950819672, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1789306, Length=276, Percent_Identity=39.8550724637681, Blast_Score=184, Evalue=9e-48,
Organism=Saccharomyces cerevisiae, GI6325146, Length=199, Percent_Identity=32.6633165829146, Blast_Score=76, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.7; =3.5.3.10 [H]

Molecular weight: Translated: 34386; Mature: 34386

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDHTHFQPLGGNEMPRCGGIATMMRLPHVASAAGLDACFVGVPFDLGTSNRTGARFGPR
CCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHH
QIRTESVLLRPYNMATRAAPFDSLQIADIGDVAINPYNLHDSIARIEAAYDAILEHDCKP
HHCCCEEEEECCCHHHHCCCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHCCCCE
ITLGGDHTIALPILRAIHRKHGKVALIHVDAHADVNDTMMGEKIAHGTPFRRAVEEGLLH
EEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCHHHCCCHHHHHHHHHHCC
GDKVTQIGLRGTGYAAEDFDWCREQGFRVVQAEECWNKSLAPLMDEVRERVGDTPVYISF
CCCEEEEECCCCCCCCHHHHHHHHCCCEEEEHHHHHCCCHHHHHHHHHHHHCCCCEEEEE
DIDGIDPAYAPGTGTPEIAGLTVPQALEIIRGARGLNIVGCDLVEVAPPYDPFGTTALLG
EECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCEECCCCCCCCCCHHHHH
ANLAYELLCVLPGVAYRD
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNDHTHFQPLGGNEMPRCGGIATMMRLPHVASAAGLDACFVGVPFDLGTSNRTGARFGPR
CCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHH
QIRTESVLLRPYNMATRAAPFDSLQIADIGDVAINPYNLHDSIARIEAAYDAILEHDCKP
HHCCCEEEEECCCHHHHCCCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHCCCCE
ITLGGDHTIALPILRAIHRKHGKVALIHVDAHADVNDTMMGEKIAHGTPFRRAVEEGLLH
EEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCHHHCCCHHHHHHHHHHCC
GDKVTQIGLRGTGYAAEDFDWCREQGFRVVQAEECWNKSLAPLMDEVRERVGDTPVYISF
CCCEEEEECCCCCCCCHHHHHHHHCCCEEEEHHHHHCCCHHHHHHHHHHHHCCCCEEEEE
DIDGIDPAYAPGTGTPEIAGLTVPQALEIIRGARGLNIVGCDLVEVAPPYDPFGTTALLG
EECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCEECCCCCCCCCCHHHHH
ANLAYELLCVLPGVAYRD
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA