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The map label for this gene is linR [H]

Identifier: 189353744

GI number: 189353744

Start: 2015121

End: 2016080

Strand: Direct

Name: linR [H]

Synonym: BMULJ_04989

Alternate gene names: 189353744

Gene position: 2015121-2016080 (Clockwise)

Preceding gene: 189353742

Following gene: 189353746

Centisome position: 81.48

GC content: 68.65

Gene sequence:

>960_bases
ATGTCACGCGTCGACCTGAACCTGCTGACCGCGCTGGATGCGTTGCTGACAGAACGCAGCGTCACCGGCGCGGCGCGCCG
CCTGAACCTGAGCGTATCGGCGACGAGCCGCACGCTCGCGCGCCTGCGCGCGCTGACGGGCGATCGCCTGTTGCTGCAGG
CAGGCCGAACGCTCGTGCTGACGCCCTACGCGGAGCAGTTGAGCCGGCGCATTCCCGCCCTCGCGCGCGAAGCGGAATCG
GTCCTGAGCCGCGCCGCGTACCGGTTCGACAGCGCGACGCTCGCGCAGCGCTTCACGTTGTGCGCGGGCGAAGGCTTCGT
CGATCTGCTCGGCGCCGCGTTGACGAACCGCGTCCGCCGCGCGGCGCCCGGCGTACAGCTGCGCTTCGTGCCGAAGCCGG
ACTGGAATGCACAGGCGTTGCGGGAGGGGCTCGTCGATCTGGAAATCGGCGTCGTGAAAACCGCGGCGCCCGAAATCCGC
ACGCGTGTGCTGTTCACGGATCGCTACGTCGGCCTGTGCAGGATCGGCCATCCGCTGCTCGCTGCGGGCGAGATCGACAT
GCAGCGATGGCTTGCATACGACCACGTGACGATCTCGCGTACCGGCGAGGCCGACAATCCGATCGACGCCCGGCTCGAAT
CGACAGGCGTGCCGCGCAACGTGCCGATCGTCGTGCCGTCCTATACCGGCGCGATGCAGCTCGTCCGTCATTCGGATCTG
CTCGCCATCGTCCCGCATTCCTGTCTCGGCAATGCGTTCATGCCCGACTACGCGGCCGAGAATGGCGTGCAATCTTTCGC
ACTGCCACTGCCGTTGCCCGCGTTCAACATCTCGGCGATCTGGCATCCGCGGCTCGATCACGATCCGGCGCACCGCTGGC
TGCGCGACGAAGTGCGCGCCGTCTGCGCGGCCGCCTATCCGGACAGCACGCCGGCCGCTCCGTCGCGCGCCGATCGCTAG

Upstream 100 bases:

>100_bases
GCATTGTCGGGATCGCGTCCGGTTTGCACCAGACGCGCCGCATGCAATCGTCGATTGCATCGGACGCCATCCGTACGGCG
TTTTCGATTATGCTCGCCGC

Downstream 100 bases:

>100_bases
GCGCCCGGCCGCCCGCTATTGCCGCGCAAGCATCAGGTCGAGGTTCTGAACCGCGGCGCCTGATGCCCCCTTGCCGAGAT
TGTCGAACACCGCGGCGAGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSRVDLNLLTALDALLTERSVTGAARRLNLSVSATSRTLARLRALTGDRLLLQAGRTLVLTPYAEQLSRRIPALAREAES
VLSRAAYRFDSATLAQRFTLCAGEGFVDLLGAALTNRVRRAAPGVQLRFVPKPDWNAQALREGLVDLEIGVVKTAAPEIR
TRVLFTDRYVGLCRIGHPLLAAGEIDMQRWLAYDHVTISRTGEADNPIDARLESTGVPRNVPIVVPSYTGAMQLVRHSDL
LAIVPHSCLGNAFMPDYAAENGVQSFALPLPLPAFNISAIWHPRLDHDPAHRWLRDEVRAVCAAAYPDSTPAAPSRADR

Sequences:

>Translated_319_residues
MSRVDLNLLTALDALLTERSVTGAARRLNLSVSATSRTLARLRALTGDRLLLQAGRTLVLTPYAEQLSRRIPALAREAES
VLSRAAYRFDSATLAQRFTLCAGEGFVDLLGAALTNRVRRAAPGVQLRFVPKPDWNAQALREGLVDLEIGVVKTAAPEIR
TRVLFTDRYVGLCRIGHPLLAAGEIDMQRWLAYDHVTISRTGEADNPIDARLESTGVPRNVPIVVPSYTGAMQLVRHSDL
LAIVPHSCLGNAFMPDYAAENGVQSFALPLPLPAFNISAIWHPRLDHDPAHRWLRDEVRAVCAAAYPDSTPAAPSRADR
>Mature_318_residues
SRVDLNLLTALDALLTERSVTGAARRLNLSVSATSRTLARLRALTGDRLLLQAGRTLVLTPYAEQLSRRIPALAREAESV
LSRAAYRFDSATLAQRFTLCAGEGFVDLLGAALTNRVRRAAPGVQLRFVPKPDWNAQALREGLVDLEIGVVKTAAPEIRT
RVLFTDRYVGLCRIGHPLLAAGEIDMQRWLAYDHVTISRTGEADNPIDARLESTGVPRNVPIVVPSYTGAMQLVRHSDLL
AIVPHSCLGNAFMPDYAAENGVQSFALPLPLPAFNISAIWHPRLDHDPAHRWLRDEVRAVCAAAYPDSTPAAPSRADR

Specific function: Positively regulates the transcription of the linD and linE genes that are involved in gamma-hexachlorocyclohexane degradation [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=307, Percent_Identity=25.7328990228013, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790147, Length=311, Percent_Identity=23.4726688102894, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081766, Length=281, Percent_Identity=28.1138790035587, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34877; Mature: 34746

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVDLNLLTALDALLTERSVTGAARRLNLSVSATSRTLARLRALTGDRLLLQAGRTLVL
CCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHHCCCHHEECCCCEEEE
TPYAEQLSRRIPALAREAESVLSRAAYRFDSATLAQRFTLCAGEGFVDLLGAALTNRVRR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AAPGVQLRFVPKPDWNAQALREGLVDLEIGVVKTAAPEIRTRVLFTDRYVGLCRIGHPLL
HCCCCEEEEECCCCCCHHHHHCCCCEEEEEEEECCCHHHHEEEEEECCHHHHHHCCCCCE
AAGEIDMQRWLAYDHVTISRTGEADNPIDARLESTGVPRNVPIVVPSYTGAMQLVRHSDL
ECCCHHHHHHHHHCCEEEEECCCCCCCHHHHHHHCCCCCCCCEEECCCHHHHHHHHHCCE
LAIVPHSCLGNAFMPDYAAENGVQSFALPLPLPAFNISAIWHPRLDHDPAHRWLRDEVRA
EEECCHHHCCCCCCCCHHHHCCCCCEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
VCAAAYPDSTPAAPSRADR
HHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRVDLNLLTALDALLTERSVTGAARRLNLSVSATSRTLARLRALTGDRLLLQAGRTLVL
CCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHHCCCHHEECCCCEEEE
TPYAEQLSRRIPALAREAESVLSRAAYRFDSATLAQRFTLCAGEGFVDLLGAALTNRVRR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AAPGVQLRFVPKPDWNAQALREGLVDLEIGVVKTAAPEIRTRVLFTDRYVGLCRIGHPLL
HCCCCEEEEECCCCCCHHHHHCCCCEEEEEEEECCCHHHHEEEEEECCHHHHHHCCCCCE
AAGEIDMQRWLAYDHVTISRTGEADNPIDARLESTGVPRNVPIVVPSYTGAMQLVRHSDL
ECCCHHHHHHHHHCCEEEEECCCCCCCHHHHHHHCCCCCCCCEEECCCHHHHHHHHHCCE
LAIVPHSCLGNAFMPDYAAENGVQSFALPLPLPAFNISAIWHPRLDHDPAHRWLRDEVRA
EEECCHHHCCCCCCCCHHHHCCCCCEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
VCAAAYPDSTPAAPSRADR
HHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11916699 [H]