BacMap

Definition	Burkholderia multivorans ATCC 17616 chromosome 2, complete genome.
Accession	NC_010805
Length	2,473,162

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The map label for this gene is fabG [H]

Identifier: 189353674

GI number: 189353674

Start: 1937321

End: 1938097

Strand: Reverse

Name: fabG [H]

Synonym: BMULJ_04919

Alternate gene names: 189353674

Gene position: 1938097-1937321 (Counterclockwise)

Preceding gene: 189353675

Following gene: 189353673

Centisome position: 78.37

GC content: 68.6

Gene sequence:

>777_bases
GTGGATCTGAATCTGCAGGACAAGGTCGTGATCGTGACGGGCGGCGCGTCGGGCATCGGCGGCGCGATCTCGATGCGGCT
CGCGGAAGAACGCGCGATTCCGGTCGTGTTCGCGCGCCACGCGCCCGACGGCGCGTTCCTCGACGCGCTCGCGCAACGCC
AGCCGCGCGCGACGTATCTGCCGGTCGAACTGCAGGACGATGCGCAATGCCGCGACGCGGTCGCGCAGACGATCGCGACG
TTCGGCCGCCTCGACGGGCTCGTGAACAACGCAGGCGTCAACGACGGCATCGGCCTCGACGCGGGGCGCGACGCGTTCGT
CGCATCGCTCGAGCGCAACCTGATCCACTACTACGCGATGGCGCATTACTGCGTGCCGCATCTGAAGGCGACGCGCGGCG
CGATCGTCAACATTTCGTCGAAGACGGCCGTGACCGGGCAGGGCAACACGAGCGGCTATTGCGCATCGAAGGGCGCGCAG
CTCGCGCTGACGCGCGAATGGGCGGTCGCGCTGCGCGAACACGGCGTGCGCGTGAACGCGGTGATTCCGGCCGAGGTCAT
GACGCCGCTCTACCGGAACTGGATCGCGACGTTCGAGGATCCCGAGGCGAAGCTCGCCGAGATCGCGGCGAAGGTGCCGC
TCGGCAGGCGCTTCACGACGCCGGACGAGATCGCCGATACGGCCGTGTTCCTGCTGTCGCCGCGCGCGTCGCACACGACG
GGCGAATGGCTGTTCGTCGACGGCGGCTATACGCATCTCGATCGTGCGCTCGTCTGA

Upstream 100 bases:

>100_bases
ATGAAGCCCGCCTCGCTCGAGCAATACCGGTTCCGCGGCTGACGCAACTGCGGCCGACAGACGGCCTGCGCGGCCGCGAC
ATGAACGACGGAGACGCGAA

Downstream 100 bases:

>100_bases
ACGCGACGGATACGCCTCATGCAAGCCGATCCGAACGCCGAAGCCGCCGCGCCGCTGATCGCGCTGCGCGGCATCTGCAA
GCGCTTTCCGGGCGTGCAGG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MDLNLQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDALAQRQPRATYLPVELQDDAQCRDAVAQTIAT
FGRLDGLVNNAGVNDGIGLDAGRDAFVASLERNLIHYYAMAHYCVPHLKATRGAIVNISSKTAVTGQGNTSGYCASKGAQ
LALTREWAVALREHGVRVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRASHTT
GEWLFVDGGYTHLDRALV

Sequences:

>Translated_258_residues
MDLNLQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDALAQRQPRATYLPVELQDDAQCRDAVAQTIAT
FGRLDGLVNNAGVNDGIGLDAGRDAFVASLERNLIHYYAMAHYCVPHLKATRGAIVNISSKTAVTGQGNTSGYCASKGAQ
LALTREWAVALREHGVRVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRASHTT
GEWLFVDGGYTHLDRALV
>Mature_258_residues
MDLNLQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDALAQRQPRATYLPVELQDDAQCRDAVAQTIAT
FGRLDGLVNNAGVNDGIGLDAGRDAFVASLERNLIHYYAMAHYCVPHLKATRGAIVNISSKTAVTGQGNTSGYCASKGAQ
LALTREWAVALREHGVRVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRASHTT
GEWLFVDGGYTHLDRALV

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI59889578, Length=203, Percent_Identity=35.9605911330049, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=34.7826086956522, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI19923817, Length=273, Percent_Identity=31.1355311355311, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=31.3253012048193, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI66933014, Length=172, Percent_Identity=33.1395348837209, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=30.0813008130081, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=28.7937743190661, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=30.1587301587302, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI31542939, Length=243, Percent_Identity=27.9835390946502, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4758504, Length=264, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=29.0836653386454, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI7706318, Length=206, Percent_Identity=26.6990291262136, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=32.6771653543307, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=30.2788844621514, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=28.4584980237154, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=30.2788844621514, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=29.8804780876494, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=30.7392996108949, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790717, Length=257, Percent_Identity=28.4046692607004, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=25.8964143426295, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI2367175, Length=260, Percent_Identity=29.2307692307692, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789057, Length=178, Percent_Identity=28.6516853932584, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=29.0196078431373, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=258, Percent_Identity=33.7209302325581, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=32.2709163346614, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=31.0344827586207, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=30.2238805970149, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=30.4182509505703, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=29.2, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=30.2325581395349, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=31.4393939393939, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=29.0697674418605, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=259, Percent_Identity=30.5019305019305, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=29.0076335877863, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=32.1969696969697, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=30.5019305019305, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=29.7297297297297, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=258, Percent_Identity=28.6821705426357, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=31.2741312741313, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=258, Percent_Identity=30.6201550387597, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=31.3953488372093, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=31.0344827586207, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=26.5682656826568, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=29.9242424242424, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=30, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=26.7716535433071, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=274, Percent_Identity=28.4671532846715, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324126, Length=193, Percent_Identity=30.0518134715026, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=36.7588932806324, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=33.0769230769231, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=32.6693227091633, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=32.8125, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=30.2788844621514, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=30.5555555555556, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=28.6852589641434, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644337, Length=169, Percent_Identity=35.5029585798817, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27680; Mature: 27680

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNLQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDALAQRQPRATYL
CCCCCCCCEEEEECCCCCCCHHHEEEEHHCCCCEEEEEECCCCHHHHHHHHHCCCCCEEE
PVELQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGLDAGRDAFVASLERNLIHYYAM
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AHYCVPHLKATRGAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVRVNA
HHHHHHHHHCCCCEEEEECCCEEEECCCCCCCEECCCCCEEEEEHHHHHHHHHCCEEEEE
VIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRASHTT
EECHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHCEEEEECCCCCCCC
GEWLFVDGGYTHLDRALV
CCEEEEECCHHHHHHHCC
>Mature Secondary Structure
MDLNLQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDALAQRQPRATYL
CCCCCCCCEEEEECCCCCCCHHHEEEEHHCCCCEEEEEECCCCHHHHHHHHHCCCCCEEE
PVELQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGLDAGRDAFVASLERNLIHYYAM
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AHYCVPHLKATRGAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVRVNA
HHHHHHHHHCCCCEEEEECCCEEEECCCCCCCEECCCCCEEEEEHHHHHHHHHCCEEEEE
VIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRASHTT
EECHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHCEEEEECCCCCCCC
GEWLFVDGGYTHLDRALV
CCEEEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]