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The map label for this gene is phnW [H]

Identifier: 189353651

GI number: 189353651

Start: 1911498

End: 1912625

Strand: Direct

Name: phnW [H]

Synonym: BMULJ_04896

Alternate gene names: 189353651

Gene position: 1911498-1912625 (Clockwise)

Preceding gene: 189353650

Following gene: 189353659

Centisome position: 77.29

GC content: 64.45

Gene sequence:

>1128_bases
GTGCCAGGATTACTTCCCGATGTCGACCGCGACGGACTGCTCGAATACTCGGTCGTCTACACGGACCGCTCGATCAATCA
CATGTCGCAGCGCTTTCAGCACGTGATGCGCGACATCTCCGATCAGCTGAAAAAGGTCTATCACGCGAAGTCGGTCGCGA
TCGTCCCCGGCAGCGGCACGTTCGGCATGGAAGCCGTTGCGCGCCAGTTCGCGACGAACAGAAAGTGCCTCGTCATCCGC
AACGGCTGGTTCAGCTACCGCTGGTCGCAGATCTTCGAGATGGGCAGCATTCCGTCCGAGTCGATCGTGCTGAAGGCACG
CCCTGTCGAATCGGGACGACAGGCCGCGTATGCGCCTGCGCCGATCGACGAAGTCGTCGCGGCGATCCGCGAGCACAAAC
CCGATCTCGTGTTCGCGCCGCATGTCGAAACCGCATCGGGGATGCTGCTGCCGGACGCTTACCTGCGCGCGGTGGCGGAC
GCGGTACATGAGGTCGGCGGCATGTTCGTGCTCGACTGCATCGCGTCCGGCACGATCTGGGTCGACATGGAAGCAAGCGG
CGTGGACGTGCTGATCAGCGCGCCGCAGAAGGGATGGAGCGCATCGCCGGGCTGCGCGCTCGTGATGCTGAGCCCGCTGG
CGCGCGAGCGGATCGACGGCACGACGAGCACGAGTTTCGCGTGCGATCTTCGCAAGTGGCTGCAGATCATGGAAGCGTAC
GAGGGCGGCGGGTTCGCGTATCACGCGACGATGCCGACCGACAGCCTCGCGACGCTGCGCGACGTGATCAAGGAGACCGA
CGCGTACGGCTTCGACAAGGTGCGCGACGAACAGCTCGAACTCGGCACGCGCATTCGCGCGCTGCTCGCCGAAAAGGGTT
TCCGGAGCGTGGCGGCGGAAGGGTTTCAGGCGCCCGGTGTGGTGGTCTGCTACACCGACGACGACGATATCCGCTCGGGC
AAGAAGTTTGCCGACGTCGGCGTGCAGATCGCGGCCGGTGTTCCGCTGCAATGCGACGAGCCCGCGGACTTCAAGACGTT
CCGGATCGGGCTGTTCGGTCTCGACAAACTGCATGACGTCGATGGCGCGGTGGCGCGGTTTGCCGATGCGTTGGAGCGGG
CTTTGTAG

Upstream 100 bases:

>100_bases
TCGTCGTCGCAGCAAACCGCAGATTTGCACGAGGCGGCTGGATTCGCTCGCGAACGCCGCGCGCGCTCATGACAGACTCA
TTCTTTCCCCGGAGGCGAAC

Downstream 100 bases:

>100_bases
GGTGGTTTTTTCGCGGTTTCGGCGCGGCAGCGGGGGTGTCGCGCCGGGAGCTGCGGGTGATTGTCGAGGGCTATGAGTGG
CGGTGACGCGGGGGATCGAT

Product: serine-glyoxylate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MPGLLPDVDRDGLLEYSVVYTDRSINHMSQRFQHVMRDISDQLKKVYHAKSVAIVPGSGTFGMEAVARQFATNRKCLVIR
NGWFSYRWSQIFEMGSIPSESIVLKARPVESGRQAAYAPAPIDEVVAAIREHKPDLVFAPHVETASGMLLPDAYLRAVAD
AVHEVGGMFVLDCIASGTIWVDMEASGVDVLISAPQKGWSASPGCALVMLSPLARERIDGTTSTSFACDLRKWLQIMEAY
EGGGFAYHATMPTDSLATLRDVIKETDAYGFDKVRDEQLELGTRIRALLAEKGFRSVAAEGFQAPGVVVCYTDDDDIRSG
KKFADVGVQIAAGVPLQCDEPADFKTFRIGLFGLDKLHDVDGAVARFADALERAL

Sequences:

>Translated_375_residues
MPGLLPDVDRDGLLEYSVVYTDRSINHMSQRFQHVMRDISDQLKKVYHAKSVAIVPGSGTFGMEAVARQFATNRKCLVIR
NGWFSYRWSQIFEMGSIPSESIVLKARPVESGRQAAYAPAPIDEVVAAIREHKPDLVFAPHVETASGMLLPDAYLRAVAD
AVHEVGGMFVLDCIASGTIWVDMEASGVDVLISAPQKGWSASPGCALVMLSPLARERIDGTTSTSFACDLRKWLQIMEAY
EGGGFAYHATMPTDSLATLRDVIKETDAYGFDKVRDEQLELGTRIRALLAEKGFRSVAAEGFQAPGVVVCYTDDDDIRSG
KKFADVGVQIAAGVPLQCDEPADFKTFRIGLFGLDKLHDVDGAVARFADALERAL
>Mature_374_residues
PGLLPDVDRDGLLEYSVVYTDRSINHMSQRFQHVMRDISDQLKKVYHAKSVAIVPGSGTFGMEAVARQFATNRKCLVIRN
GWFSYRWSQIFEMGSIPSESIVLKARPVESGRQAAYAPAPIDEVVAAIREHKPDLVFAPHVETASGMLLPDAYLRAVADA
VHEVGGMFVLDCIASGTIWVDMEASGVDVLISAPQKGWSASPGCALVMLSPLARERIDGTTSTSFACDLRKWLQIMEAYE
GGGFAYHATMPTDSLATLRDVIKETDAYGFDKVRDEQLELGTRIRALLAEKGFRSVAAEGFQAPGVVVCYTDDDDIRSGK
KFADVGVQIAAGVPLQCDEPADFKTFRIGLFGLDKLHDVDGAVARFADALERAL

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=365, Percent_Identity=24.3835616438356, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17536281, Length=342, Percent_Identity=25.4385964912281, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6321079, Length=275, Percent_Identity=25.0909090909091, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 40955; Mature: 40824

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGLLPDVDRDGLLEYSVVYTDRSINHMSQRFQHVMRDISDQLKKVYHAKSVAIVPGSGT
CCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
FGMEAVARQFATNRKCLVIRNGWFSYRWSQIFEMGSIPSESIVLKARPVESGRQAAYAPA
CCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCC
PIDEVVAAIREHKPDLVFAPHVETASGMLLPDAYLRAVADAVHEVGGMFVLDCIASGTIW
CHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHCCCEEE
VDMEASGVDVLISAPQKGWSASPGCALVMLSPLARERIDGTTSTSFACDLRKWLQIMEAY
EEEECCCCEEEEECCCCCCCCCCCEEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
EGGGFAYHATMPTDSLATLRDVIKETDAYGFDKVRDEQLELGTRIRALLAEKGFRSVAAE
CCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFQAPGVVVCYTDDDDIRSGKKFADVGVQIAAGVPLQCDEPADFKTFRIGLFGLDKLHDV
CCCCCCEEEEECCCHHHHCCCHHHHCCEEEECCCCCCCCCCCCCEEEEEEEECCHHHHHH
DGAVARFADALERAL
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
PGLLPDVDRDGLLEYSVVYTDRSINHMSQRFQHVMRDISDQLKKVYHAKSVAIVPGSGT
CCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
FGMEAVARQFATNRKCLVIRNGWFSYRWSQIFEMGSIPSESIVLKARPVESGRQAAYAPA
CCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCC
PIDEVVAAIREHKPDLVFAPHVETASGMLLPDAYLRAVADAVHEVGGMFVLDCIASGTIW
CHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHCCCEEE
VDMEASGVDVLISAPQKGWSASPGCALVMLSPLARERIDGTTSTSFACDLRKWLQIMEAY
EEEECCCCEEEEECCCCCCCCCCCEEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
EGGGFAYHATMPTDSLATLRDVIKETDAYGFDKVRDEQLELGTRIRALLAEKGFRSVAAE
CCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFQAPGVVVCYTDDDDIRSGKKFADVGVQIAAGVPLQCDEPADFKTFRIGLFGLDKLHDV
CCCCCCEEEEECCCHHHHCCCHHHHCCEEEECCCCCCCCCCCCCEEEEEEEECCHHHHHH
DGAVARFADALERAL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA