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The map label for this gene is virS [H]

Identifier: 189353604

GI number: 189353604

Start: 1860390

End: 1861406

Strand: Direct

Name: virS [H]

Synonym: BMULJ_04848

Alternate gene names: 189353604

Gene position: 1860390-1861406 (Clockwise)

Preceding gene: 189353600

Following gene: 189353605

Centisome position: 75.22

GC content: 64.31

Gene sequence:

>1017_bases
ATGGATCCCTTGCTCAGAGCGAGCGGCCTTCGCGGCTACCCTGCCCTCATGCGCGACATGGGCTGCGATCCCGTGCCGTT
GCTGCGCCGGTATCACATCACGGAAGCGGCACTGGAACGCGACGACACGCTGATATCGCTGCGCTCCGCCACGCATCTGC
TGGAAGCCAGCGCCGAGGTGACCGGATGTGGCGATTTCGGCCTGCGCCTGTCGTCGTATCAAAGCATCGACGTGCTCGGT
CCGTTGAGCGTCGTGCTGCGCAACGCGCCCACGATCCGCGATGCGCTGAACGATGTGATGCGCTACCTGTTCGTGCACAG
CCCGGGCATCGTCGTATCGGTCAACGAGCGTAGCCGTCTGGTCGAGAACACCGTCGCGGTGTCCGTCGAACTTCACCTGT
CGGGTCCGGTCGTCACCCGGCAAAACAGCGACCTGTGCCTCGCGGACGCACACAACTTCCTGCGGCTCTTTGCCGGAGAC
CGCTACGCGCTGCAAGCGGTATCGATACCGCACGAACCGGTCGTCGGCCGCGCGGTGTATGAGCGCTTCTTCGGCGCGAG
ACTGCTGGAGGAACCGGTCGGCGCCACGCTGTATCTGGCGCGCGATACGTTCGCGGCCAATGTGCAGGGCGCGAACGCAT
CGTTTCACCAGATCGCGGAAGACTACATTTTCCGGAATTTCGGGGCCGCTCAAGGAAGCACGTCGGATCGCGTCCGTCAG
GTGTTGCGGCAAACGCTCGGCACGTCGAGCGCCGACAAGGCCGGCGTCGCCGCCGTGCTTGCGCTGCATCCGAGAACGCT
GCAGCGTCGCCTCTGCGCGGAGGGGACGAGCTTCGAAATTCTCCGGGACGACGTCCGCAAGCAGCTCGCCGTGCACTATC
TTCGCAACACCCGGCTGAGCATCGGCCAGATTTCGTTGATGCTCGGCTTTCCTGCGCAATCGGCGTTATCGCGAGCTTGC
CGCCAGTGGTTCGATCTCACGCCCTCGGAAATCCGCGTCGGCAATCGGCCAACGTGA

Upstream 100 bases:

>100_bases
ATCGGATGTCTCCTCGTTGTTGGTGATCGACACCCGCACTCTAGCAATCGCGCACGCGCGCTATTTGACGTCACGAGACT
ATTGTTTTACATTTTGAGAC

Downstream 100 bases:

>100_bases
GTGCCGCCGCGCGGCAAAGTTGACCATCGCGTAGGATGCACGACACGCCGTGCGCCTACGCTGGACGGTCGATACACTTT
GCCGGTACAAATAGCGCTAT

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MDPLLRASGLRGYPALMRDMGCDPVPLLRRYHITEAALERDDTLISLRSATHLLEASAEVTGCGDFGLRLSSYQSIDVLG
PLSVVLRNAPTIRDALNDVMRYLFVHSPGIVVSVNERSRLVENTVAVSVELHLSGPVVTRQNSDLCLADAHNFLRLFAGD
RYALQAVSIPHEPVVGRAVYERFFGARLLEEPVGATLYLARDTFAANVQGANASFHQIAEDYIFRNFGAAQGSTSDRVRQ
VLRQTLGTSSADKAGVAAVLALHPRTLQRRLCAEGTSFEILRDDVRKQLAVHYLRNTRLSIGQISLMLGFPAQSALSRAC
RQWFDLTPSEIRVGNRPT

Sequences:

>Translated_338_residues
MDPLLRASGLRGYPALMRDMGCDPVPLLRRYHITEAALERDDTLISLRSATHLLEASAEVTGCGDFGLRLSSYQSIDVLG
PLSVVLRNAPTIRDALNDVMRYLFVHSPGIVVSVNERSRLVENTVAVSVELHLSGPVVTRQNSDLCLADAHNFLRLFAGD
RYALQAVSIPHEPVVGRAVYERFFGARLLEEPVGATLYLARDTFAANVQGANASFHQIAEDYIFRNFGAAQGSTSDRVRQ
VLRQTLGTSSADKAGVAAVLALHPRTLQRRLCAEGTSFEILRDDVRKQLAVHYLRNTRLSIGQISLMLGFPAQSALSRAC
RQWFDLTPSEIRVGNRPT
>Mature_338_residues
MDPLLRASGLRGYPALMRDMGCDPVPLLRRYHITEAALERDDTLISLRSATHLLEASAEVTGCGDFGLRLSSYQSIDVLG
PLSVVLRNAPTIRDALNDVMRYLFVHSPGIVVSVNERSRLVENTVAVSVELHLSGPVVTRQNSDLCLADAHNFLRLFAGD
RYALQAVSIPHEPVVGRAVYERFFGARLLEEPVGATLYLARDTFAANVQGANASFHQIAEDYIFRNFGAAQGSTSDRVRQ
VLRQTLGTSSADKAGVAAVLALHPRTLQRRLCAEGTSFEILRDDVRKQLAVHYLRNTRLSIGQISLMLGFPAQSALSRAC
RQWFDLTPSEIRVGNRPT

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37225; Mature: 37225

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPLLRASGLRGYPALMRDMGCDPVPLLRRYHITEAALERDDTLISLRSATHLLEASAEV
CCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCC
TGCGDFGLRLSSYQSIDVLGPLSVVLRNAPTIRDALNDVMRYLFVHSPGIVVSVNERSRL
CCCCHHCCEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHH
VENTVAVSVELHLSGPVVTRQNSDLCLADAHNFLRLFAGDRYALQAVSIPHEPVVGRAVY
HHCEEEEEEEEEECCCEEECCCCCEEHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
ERFFGARLLEEPVGATLYLARDTFAANVQGANASFHQIAEDYIFRNFGAAQGSTSDRVRQ
HHHHHHHHHHCCCCCEEEEEECCCEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
VLRQTLGTSSADKAGVAAVLALHPRTLQRRLCAEGTSFEILRDDVRKQLAVHYLRNTRLS
HHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
IGQISLMLGFPAQSALSRACRQWFDLTPSEIRVGNRPT
CEEEEEEECCCHHHHHHHHHHHHHCCCHHHCCCCCCCC
>Mature Secondary Structure
MDPLLRASGLRGYPALMRDMGCDPVPLLRRYHITEAALERDDTLISLRSATHLLEASAEV
CCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCC
TGCGDFGLRLSSYQSIDVLGPLSVVLRNAPTIRDALNDVMRYLFVHSPGIVVSVNERSRL
CCCCHHCCEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHH
VENTVAVSVELHLSGPVVTRQNSDLCLADAHNFLRLFAGDRYALQAVSIPHEPVVGRAVY
HHCEEEEEEEEEECCCEEECCCCCEEHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
ERFFGARLLEEPVGATLYLARDTFAANVQGANASFHQIAEDYIFRNFGAAQGSTSDRVRQ
HHHHHHHHHHCCCCCEEEEEECCCEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
VLRQTLGTSSADKAGVAAVLALHPRTLQRRLCAEGTSFEILRDDVRKQLAVHYLRNTRLS
HHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
IGQISLMLGFPAQSALSRACRQWFDLTPSEIRVGNRPT
CEEEEEEECCCHHHHHHHHHHHHHCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]