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The map label for this gene is atoC [H]

Identifier: 189353497

GI number: 189353497

Start: 1716281

End: 1717702

Strand: Reverse

Name: atoC [H]

Synonym: BMULJ_04741

Alternate gene names: 189353497

Gene position: 1717702-1716281 (Counterclockwise)

Preceding gene: 189353498

Following gene: 189353495

Centisome position: 69.45

GC content: 69.69

Gene sequence:

>1422_bases
GTGAACAACCGTTGCCCGATCAGTTTCTCCGCCTCGCAGCACAGCGAGCCGCTCGTGTGCCCGCCGTCGTTCGCGGCGCT
TCGGCGCAACCGCGTGCTGCCGGCGCGGCCGCTCGTCTATTTGTCGCCGCACCCCGACGCCGCGCTCGTCGACTGTCTTG
CGTCGAACGGATGGGACGTGTGGCACGCGAAGACCGTTGCGGACGCACTCAATTGCCTGCGCGGCAATCGGCTGTACGCG
GGCATCGTCGATTTCGACGGGTTCGCCGCGCTCGACGTCGCCGCGTTCGAGGCGGTGCTGCGCGATCCGCGCGTGGGCTG
GGTCGCGCTGGCCGGCGACGCGCGGCTGAAGGACGTCGCGCTGTGCCGGCTGATTCGCCAGTGCTGCTTCGACTACGTGC
GCAACGCGAGCGCGTATACGACGATCGGCTATCTCGTCGGCCATGCGTACGGGATGCTGAAGCTCGCGGAAGCCGATCCG
GACCGGCAGACCGACGCGCCGGGCGGCACGATGATCGGCGCGTGCGACGCGATGCGCCGGCTGTTCGCGACGATCCGCAA
GGTCGCGAACACCGATGCGGCCGTGTTCGTCGCCGGCGAGTCGGGCACCGGCAAGGAATTGACGGCCGCCGCGATCCACC
AGCAGTCGGCGCGCGCGCACGGGCCGTTCGTGCCGGTCAACTGCGCGGCGATTCCGCCGACGCTGCTGCAGGCCGAGCTG
TTCGGCTACGAGCGCGGCGCGTTTACGGGCGCGCATCAGCGCAAGATCGGCCGCATCGAGGCCGCGCACGGCGGCACGCT
GTTTCTCGACGAGATCGGCGACATGCCGTTCGAGAGCCAGGCGAGCCTGCTGCGCTTTCTGCAGCAGGGGACGATCGAGC
GTCTCGGCGGCCATGCGTCGATTCCGGTCGACGTGCGGATCGTGTCGGCCACGCACGTCGATCTCGAAGCGGCGATGCAG
GACGGGCGGTTCCGCGCGGATCTCTACTACCGGCTGTGCGTGATGCGGATCGACGAGCCGCCGCTACGCGCACGCGGCCG
CGACATCATGCTGCTCGCCGAGCACATGCTGCAGCGGTTTCGCGGCGACTGCGCGCACCGGATCCGCGGCTTCGCGCCGT
GCGCGGTGGAGGCGATCTACAACTATGGCTGGCCCGGCAACGTGCGCGAACTGATCAACCGGATCCGCTTCGCGATCGTG
ATGACGAACGGCGCGACGATCACGGCCGCCGATCTGGAGCTCGGCGCCTATACGTCGCAACGGCCGCCGACGCTTGCCGA
AGCGCGCCGGCAGGCCGAGCGGCGCGCGATCGAAGAGACGCTGATGCGCCATCGCCACCAGCATGCGGACGTCGCGGCGG
AACTCGGCGTGTCGCGTGCGACGCTGTACCGGCTGATGACCGCGCACGGGCTGCACGCGTAA

Upstream 100 bases:

>100_bases
CCACTTGATCCCGGCGCACGCCGGTATTGCGCGACGCGGCGACGCGACAGCGCGCCGTACCGCACCGGCGTAGCCGATTC
CGCCTTGCGGCGAGGCCACC

Downstream 100 bases:

>100_bases
CGCGCGCTCGCGCAGGGCGGCACGCGCCGTGCCCGACGCGCCTGGGGCGCCCGGTGCGTTGCGCGCCGCGCATCACGCCG
GCCGCGCGTACCCCGATTCG

Product: sigma54-dependent DNA-binding transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MNNRCPISFSASQHSEPLVCPPSFAALRRNRVLPARPLVYLSPHPDAALVDCLASNGWDVWHAKTVADALNCLRGNRLYA
GIVDFDGFAALDVAAFEAVLRDPRVGWVALAGDARLKDVALCRLIRQCCFDYVRNASAYTTIGYLVGHAYGMLKLAEADP
DRQTDAPGGTMIGACDAMRRLFATIRKVANTDAAVFVAGESGTGKELTAAAIHQQSARAHGPFVPVNCAAIPPTLLQAEL
FGYERGAFTGAHQRKIGRIEAAHGGTLFLDEIGDMPFESQASLLRFLQQGTIERLGGHASIPVDVRIVSATHVDLEAAMQ
DGRFRADLYYRLCVMRIDEPPLRARGRDIMLLAEHMLQRFRGDCAHRIRGFAPCAVEAIYNYGWPGNVRELINRIRFAIV
MTNGATITAADLELGAYTSQRPPTLAEARRQAERRAIEETLMRHRHQHADVAAELGVSRATLYRLMTAHGLHA

Sequences:

>Translated_473_residues
MNNRCPISFSASQHSEPLVCPPSFAALRRNRVLPARPLVYLSPHPDAALVDCLASNGWDVWHAKTVADALNCLRGNRLYA
GIVDFDGFAALDVAAFEAVLRDPRVGWVALAGDARLKDVALCRLIRQCCFDYVRNASAYTTIGYLVGHAYGMLKLAEADP
DRQTDAPGGTMIGACDAMRRLFATIRKVANTDAAVFVAGESGTGKELTAAAIHQQSARAHGPFVPVNCAAIPPTLLQAEL
FGYERGAFTGAHQRKIGRIEAAHGGTLFLDEIGDMPFESQASLLRFLQQGTIERLGGHASIPVDVRIVSATHVDLEAAMQ
DGRFRADLYYRLCVMRIDEPPLRARGRDIMLLAEHMLQRFRGDCAHRIRGFAPCAVEAIYNYGWPGNVRELINRIRFAIV
MTNGATITAADLELGAYTSQRPPTLAEARRQAERRAIEETLMRHRHQHADVAAELGVSRATLYRLMTAHGLHA
>Mature_473_residues
MNNRCPISFSASQHSEPLVCPPSFAALRRNRVLPARPLVYLSPHPDAALVDCLASNGWDVWHAKTVADALNCLRGNRLYA
GIVDFDGFAALDVAAFEAVLRDPRVGWVALAGDARLKDVALCRLIRQCCFDYVRNASAYTTIGYLVGHAYGMLKLAEADP
DRQTDAPGGTMIGACDAMRRLFATIRKVANTDAAVFVAGESGTGKELTAAAIHQQSARAHGPFVPVNCAAIPPTLLQAEL
FGYERGAFTGAHQRKIGRIEAAHGGTLFLDEIGDMPFESQASLLRFLQQGTIERLGGHASIPVDVRIVSATHVDLEAAMQ
DGRFRADLYYRLCVMRIDEPPLRARGRDIMLLAEHMLQRFRGDCAHRIRGFAPCAVEAIYNYGWPGNVRELINRIRFAIV
MTNGATITAADLELGAYTSQRPPTLAEARRQAERRAIEETLMRHRHQHADVAAELGVSRATLYRLMTAHGLHA

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=362, Percent_Identity=40.3314917127072, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1790437, Length=355, Percent_Identity=41.1267605633803, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1790299, Length=376, Percent_Identity=39.0957446808511, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI87082117, Length=259, Percent_Identity=47.8764478764479, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1788905, Length=299, Percent_Identity=43.4782608695652, Blast_Score=231, Evalue=5e-62,
Organism=Escherichia coli, GI1789233, Length=319, Percent_Identity=42.6332288401254, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1789087, Length=359, Percent_Identity=38.7186629526462, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1786524, Length=313, Percent_Identity=41.85303514377, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI87081872, Length=320, Percent_Identity=36.5625, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI87082152, Length=317, Percent_Identity=40.6940063091483, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1787583, Length=309, Percent_Identity=35.2750809061489, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI87081858, Length=302, Percent_Identity=32.7814569536424, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789828, Length=236, Percent_Identity=33.0508474576271, Blast_Score=115, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51846; Mature: 51846

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNRCPISFSASQHSEPLVCPPSFAALRRNRVLPARPLVYLSPHPDAALVDCLASNGWDV
CCCCCCEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHCCCCCC
WHAKTVADALNCLRGNRLYAGIVDFDGFAALDVAAFEAVLRDPRVGWVALAGDARLKDVA
HHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHH
LCRLIRQCCFDYVRNASAYTTIGYLVGHAYGMLKLAEADPDRQTDAPGGTMIGACDAMRR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCEEHHHHHHHH
LFATIRKVANTDAAVFVAGESGTGKELTAAAIHQQSARAHGPFVPVNCAAIPPTLLQAEL
HHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHH
FGYERGAFTGAHQRKIGRIEAAHGGTLFLDEIGDMPFESQASLLRFLQQGTIERLGGHAS
HCCCCCCCCCHHHHHHCCEEECCCCEEEEHHHCCCCCCHHHHHHHHHHHCCHHHCCCCCC
IPVDVRIVSATHVDLEAAMQDGRFRADLYYRLCVMRIDEPPLRARGRDIMLLAEHMLQRF
CCEEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
RGDCAHRIRGFAPCAVEAIYNYGWPGNVRELINRIRFAIVMTNGATITAADLELGAYTSQ
HHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHEEEEEEECCCEEEEECCEECCCCCC
RPPTLAEARRQAERRAIEETLMRHRHQHADVAAELGVSRATLYRLMTAHGLHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNNRCPISFSASQHSEPLVCPPSFAALRRNRVLPARPLVYLSPHPDAALVDCLASNGWDV
CCCCCCEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHCCCCCC
WHAKTVADALNCLRGNRLYAGIVDFDGFAALDVAAFEAVLRDPRVGWVALAGDARLKDVA
HHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHH
LCRLIRQCCFDYVRNASAYTTIGYLVGHAYGMLKLAEADPDRQTDAPGGTMIGACDAMRR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCEEHHHHHHHH
LFATIRKVANTDAAVFVAGESGTGKELTAAAIHQQSARAHGPFVPVNCAAIPPTLLQAEL
HHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHH
FGYERGAFTGAHQRKIGRIEAAHGGTLFLDEIGDMPFESQASLLRFLQQGTIERLGGHAS
HCCCCCCCCCHHHHHHCCEEECCCCEEEEHHHCCCCCCHHHHHHHHHHHCCHHHCCCCCC
IPVDVRIVSATHVDLEAAMQDGRFRADLYYRLCVMRIDEPPLRARGRDIMLLAEHMLQRF
CCEEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
RGDCAHRIRGFAPCAVEAIYNYGWPGNVRELINRIRFAIVMTNGATITAADLELGAYTSQ
HHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHEEEEEEECCCEEEEECCEECCCCCC
RPPTLAEARRQAERRAIEETLMRHRHQHADVAAELGVSRATLYRLMTAHGLHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]