| Definition | Burkholderia multivorans ATCC 17616 chromosome 2, complete genome. |
|---|---|
| Accession | NC_010805 |
| Length | 2,473,162 |
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The map label for this gene is fabG [H]
Identifier: 189353470
GI number: 189353470
Start: 1689418
End: 1690227
Strand: Reverse
Name: fabG [H]
Synonym: BMULJ_04714
Alternate gene names: 189353470
Gene position: 1690227-1689418 (Counterclockwise)
Preceding gene: 189353471
Following gene: 189353469
Centisome position: 68.34
GC content: 70.49
Gene sequence:
>810_bases ATGACGGCCGCGCTCGGTAGCGGCCGCGTGCGCGCGGACTTCACCGGCCGCGTCGTGCTCGTGACGGGCGCGGCGCACGG CATCGGCGCCGCGATCGCGCGACGCTTCGCGGAATCCGACGCGTTCGTCGCGCTCGCGGATCTCGACGAAGCCGCCGCCG TCGCGCAGGCCGATGCGATCGCGCGCGCAGGCGGCGCCGCACGCGCGTACCGCGTCGATGCGGGAAGCCGCGACGAGCTT TGTGCACTCGTTAGCGACGTGGAGCGCGACGGCGGACGGCTCGACGTCGTCGTCCACAATGCGGCGTATTTTCCGCTGAC GCCGTTCGTCGACATCGACGTGCAGACGCTCGAACGCACACTGTCGGTCAACCTGTCGGCACTGTTCTGGCTCGCGCAGG CGGCACTGCCCGCATTCGAGCGTGCAGAAGGCGGGCGGCTGCTCGTGACGTCGTCGGTGACGGGGCCACGCGTCGCGTTT CCCGGGCTCGCGCACTACGCGGCATCGAAGGCGGGTGTGAACGGCTTCATTCGTGCGGCAGCGCTCGAGCTGGCGCGCCG CAACGTGACGGTCAACGGCGTCGAGCCGGGGATGATCCGCACGTCGGCGGCCGGCAATCTCGGCGACGCCTCCGTTGCGG AGCGCATCGCGCGCGACATTCCGCTCGCGAGAATGGGCGAGCCGGACGACATCGCGAACGCGATGCTGTATCTCGCGTCG GCTGATGCCGCGTATGTCACGGGGCAGACGATCGTCGTCGACGGTGGCGCGACGCTGCCGGAAAGCGGCGCCGCGCTCGA TGCGATATAG
Upstream 100 bases:
>100_bases GCTACGCGCAAGACGACTTCGGCACGCTGTCGAACTTCCCCGTCGGCGCGCATGCGCAGGTGCTGAACGAAACCGTGCAT CCGCTCGACGGTGTGCAGCG
Downstream 100 bases:
>100_bases CGCAAGGGCAGGTTTCGCCGCGCGACGCGCGGCGACGGCATGGGCGGTCGTTCGGGTGCGGTGCGGACCGCTCGACGGAG CGCGTCGTGTCGACGCTCGA
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: Acetoin(diacetyl) reductase; AR; Meso-2,3-butanediol dehydrogenase [H]
Number of amino acids: Translated: 269; Mature: 268
Protein sequence:
>269_residues MTAALGSGRVRADFTGRVVLVTGAAHGIGAAIARRFAESDAFVALADLDEAAAVAQADAIARAGGAARAYRVDAGSRDEL CALVSDVERDGGRLDVVVHNAAYFPLTPFVDIDVQTLERTLSVNLSALFWLAQAALPAFERAEGGRLLVTSSVTGPRVAF PGLAHYAASKAGVNGFIRAAALELARRNVTVNGVEPGMIRTSAAGNLGDASVAERIARDIPLARMGEPDDIANAMLYLAS ADAAYVTGQTIVVDGGATLPESGAALDAI
Sequences:
>Translated_269_residues MTAALGSGRVRADFTGRVVLVTGAAHGIGAAIARRFAESDAFVALADLDEAAAVAQADAIARAGGAARAYRVDAGSRDEL CALVSDVERDGGRLDVVVHNAAYFPLTPFVDIDVQTLERTLSVNLSALFWLAQAALPAFERAEGGRLLVTSSVTGPRVAF PGLAHYAASKAGVNGFIRAAALELARRNVTVNGVEPGMIRTSAAGNLGDASVAERIARDIPLARMGEPDDIANAMLYLAS ADAAYVTGQTIVVDGGATLPESGAALDAI >Mature_268_residues TAALGSGRVRADFTGRVVLVTGAAHGIGAAIARRFAESDAFVALADLDEAAAVAQADAIARAGGAARAYRVDAGSRDELC ALVSDVERDGGRLDVVVHNAAYFPLTPFVDIDVQTLERTLSVNLSALFWLAQAALPAFERAEGGRLLVTSSVTGPRVAFP GLAHYAASKAGVNGFIRAAALELARRNVTVNGVEPGMIRTSAAGNLGDASVAERIARDIPLARMGEPDDIANAMLYLASA DAAYVTGQTIVVDGGATLPESGAALDAI
Specific function: Catalyzes the reversible reduction of (S)-acetoin to 2,3-butanediol in the presence of NADH [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=261, Percent_Identity=34.8659003831418, Blast_Score=135, Evalue=4e-32, Organism=Homo sapiens, GI126723750, Length=261, Percent_Identity=31.4176245210728, Blast_Score=111, Evalue=6e-25, Organism=Homo sapiens, GI15277342, Length=246, Percent_Identity=33.739837398374, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=34.8, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=28.2352941176471, Blast_Score=104, Evalue=9e-23, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=30.327868852459, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI210032110, Length=174, Percent_Identity=29.8850574712644, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI142976729, Length=230, Percent_Identity=26.5217391304348, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI126723191, Length=207, Percent_Identity=32.3671497584541, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=29.6, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=29.2181069958848, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=31.4893617021277, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI310128830, Length=204, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI310115468, Length=204, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI40807363, Length=198, Percent_Identity=28.2828282828283, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI33667109, Length=248, Percent_Identity=32.258064516129, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4504505, Length=217, Percent_Identity=33.1797235023041, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=25.8964143426295, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI31542939, Length=245, Percent_Identity=29.7959183673469, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI7657478, Length=207, Percent_Identity=28.5024154589372, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI25282469, Length=194, Percent_Identity=26.2886597938144, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI109715829, Length=242, Percent_Identity=24.7933884297521, Blast_Score=66, Evalue=4e-11, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=32.421875, Blast_Score=134, Evalue=6e-33, Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=34.5238095238095, Blast_Score=131, Evalue=5e-32, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=34.8360655737705, Blast_Score=121, Evalue=4e-29, Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=33.469387755102, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=29.3388429752066, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=31.0204081632653, Blast_Score=107, Evalue=6e-25, Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=33.2046332046332, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI1789378, Length=261, Percent_Identity=31.4176245210728, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=29.0983606557377, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=29.3172690763052, Blast_Score=97, Evalue=8e-22, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=29.1828793774319, Blast_Score=81, Evalue=9e-17, Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=25.6198347107438, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1787526, Length=239, Percent_Identity=30.1255230125523, Blast_Score=72, Evalue=3e-14, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=36.5853658536585, Blast_Score=127, Evalue=6e-30, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=3e-28, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=31.6205533596838, Blast_Score=120, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=32.824427480916, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=29.0076335877863, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=30.8, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=28.6792452830189, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17531453, Length=272, Percent_Identity=29.0441176470588, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=32.4427480916031, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=30.5660377358491, Blast_Score=104, Evalue=6e-23, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=31.5789473684211, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=29.9242424242424, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=30.5220883534137, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=29.3233082706767, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=26.7924528301887, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=29.0076335877863, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=28.4090909090909, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=27.3764258555133, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=26.6917293233083, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=27.5471698113208, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17564282, Length=194, Percent_Identity=30.4123711340206, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=27.3764258555133, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=27.8195488721804, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI115534694, Length=261, Percent_Identity=30.2681992337165, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=29.3814432989691, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17560332, Length=273, Percent_Identity=28.2051282051282, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=26.8774703557312, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=27.9245283018868, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI193203117, Length=189, Percent_Identity=29.1005291005291, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17567345, Length=172, Percent_Identity=29.0697674418605, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=27.1794871794872, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17536025, Length=274, Percent_Identity=28.4671532846715, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17536651, Length=262, Percent_Identity=25.1908396946565, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI193207185, Length=148, Percent_Identity=30.4054054054054, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=28.6458333333333, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17538182, Length=259, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=27.843137254902, Blast_Score=84, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6322861, Length=234, Percent_Identity=28.6324786324786, Blast_Score=80, Evalue=3e-16, Organism=Saccharomyces cerevisiae, GI6323882, Length=267, Percent_Identity=24.3445692883895, Blast_Score=65, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322227, Length=202, Percent_Identity=28.2178217821782, Blast_Score=64, Evalue=4e-11, Organism=Drosophila melanogaster, GI24644337, Length=259, Percent_Identity=36.2934362934363, Blast_Score=117, Evalue=1e-26, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=33.8709677419355, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=6e-26, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=33.0677290836653, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=29.7959183673469, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI24640492, Length=199, Percent_Identity=31.1557788944724, Blast_Score=101, Evalue=6e-22, Organism=Drosophila melanogaster, GI281364892, Length=225, Percent_Identity=28.8888888888889, Blast_Score=98, Evalue=5e-21, Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=29.1828793774319, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=32.1285140562249, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24581726, Length=169, Percent_Identity=30.1775147928994, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI21355631, Length=178, Percent_Identity=27.5280898876405, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24649181, Length=194, Percent_Identity=28.8659793814433, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI18859837, Length=198, Percent_Identity=33.8383838383838, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI221510726, Length=233, Percent_Identity=26.6094420600858, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=29.0196078431373, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014007 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.304 [H]
Molecular weight: Translated: 27573; Mature: 27442
Theoretical pI: Translated: 4.70; Mature: 4.70
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTAALGSGRVRADFTGRVVLVTGAAHGIGAAIARRFAESDAFVALADLDEAAAVAQADAI CCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH ARAGGAARAYRVDAGSRDELCALVSDVERDGGRLDVVVHNAAYFPLTPFVDIDVQTLERT HHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCEECCCCCEEECCHHHHHHH LSVNLSALFWLAQAALPAFERAEGGRLLVTSSVTGPRVAFPGLAHYAASKAGVNGFIRAA HHCCHHHHHHHHHHHCCHHHHCCCCEEEEEECCCCCCEECCCHHHHHHHHCCCHHHHHHH ALELARRNVTVNGVEPGMIRTSAAGNLGDASVAERIARDIPLARMGEPDDIANAMLYLAS HHHHHHCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHHCCHHHCCCCHHHHHHHHHEEC ADAAYVTGQTIVVDGGATLPESGAALDAI CCCEEEECCEEEEECCCCCCCCCCCCCCC >Mature Secondary Structure TAALGSGRVRADFTGRVVLVTGAAHGIGAAIARRFAESDAFVALADLDEAAAVAQADAI CCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH ARAGGAARAYRVDAGSRDELCALVSDVERDGGRLDVVVHNAAYFPLTPFVDIDVQTLERT HHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCEECCCCCEEECCHHHHHHH LSVNLSALFWLAQAALPAFERAEGGRLLVTSSVTGPRVAFPGLAHYAASKAGVNGFIRAA HHCCHHHHHHHHHHHCCHHHHCCCCEEEEEECCCCCCEECCCHHHHHHHHCCCHHHHHHH ALELARRNVTVNGVEPGMIRTSAAGNLGDASVAERIARDIPLARMGEPDDIANAMLYLAS HHHHHHCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHHCCHHHCCCCHHHHHHHHHEEC ADAAYVTGQTIVVDGGATLPESGAALDAI CCCEEEECCEEEEECCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11173520 [H]