BacMap

Definition	Burkholderia multivorans ATCC 17616 chromosome 2, complete genome.
Accession	NC_010805
Length	2,473,162

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The map label for this gene is fabG [H]

Identifier: 189353469

GI number: 189353469

Start: 1687988

End: 1688701

Strand: Reverse

Name: fabG [H]

Synonym: BMULJ_04713

Alternate gene names: 189353469

Gene position: 1688701-1687988 (Counterclockwise)

Preceding gene: 189353470

Following gene: 189353467

Centisome position: 68.28

GC content: 70.17

Gene sequence:

>714_bases
ATGGAGCAACACATCAACGGAAAAGTCGTCGCGATTACCGGCGGCTTCGGCCATCTCGGCATCGCGACGGCGGCATGGCT
CGGCGCGCGAGGCGCCCGCGTCGCGCTGATCGGCCGCGGCGCCGCGCCCGATTCGAACGCGCTGCCCGACGTGCCGGCCA
CCGCGCTGCGGCTCGGCGGCATCGATCTCGTCGATCCGCAGGCCGCCGTGCACGCACTCGACGCCGTGCATCGCCAGTTC
GGCGGGGTCGACGCGCTGCTCAACATCGCGGGCGCATTCGTGTGGCAAACGATCGCGGACGGCGATGTCGACACCTGGGA
CCGCATGTACGCGCTGAACGTGAAAACGGCGCTGAATGCGTCGAAGGCCGCGCTGCCGTATCTGCTGCAGAGCGCCGCCG
GCCGCATCGTCAATATCGGCGCGGGCGCGGCATCGAAGGCGGGCACCGGCATGGGCGCCTATGCGGCCGCGAAGGCGGGC
GTCGCCCGGCTCACCGAGGCGTTGGCGGCCGAGCTGCTCGATCGCGGCATCACGGTGAACGCGGTCCTGCCGAGCATCAT
CGACACGCCGTCGAATCGCGCCGACATGCCCGACGCCGATTTCACGCGCTGGGTGCAACCCCAGCAGATCGCGGCGACGA
TCGGATTTCTGCTGTCGCCCGAAGCGCAGGCCATCTCGGGCGCCTCGATTCCGGTCAGCGGGCGCGTCGCGTAA

Upstream 100 bases:

>100_bases
GCGGTCACATCCAACGTGACCCGTCCGTCGTCCTGCACCGACCGCGCGCACCGAACACACGCGCCGCACGCGAACCCGAT
CAATCACGGAGAGCAATTCG

Downstream 100 bases:

>100_bases
CGATTGCGCGCGCGGCGGCACGCCGATGCGCGCCGCCTGCGCGGCGCGTCATTCCTGGATCAGGAAGCGATCGCGATTCT
TCACGTCCTTGATCCAGCCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MEQHINGKVVAITGGFGHLGIATAAWLGARGARVALIGRGAAPDSNALPDVPATALRLGGIDLVDPQAAVHALDAVHRQF
GGVDALLNIAGAFVWQTIADGDVDTWDRMYALNVKTALNASKAALPYLLQSAAGRIVNIGAGAASKAGTGMGAYAAAKAG
VARLTEALAAELLDRGITVNAVLPSIIDTPSNRADMPDADFTRWVQPQQIAATIGFLLSPEAQAISGASIPVSGRVA

Sequences:

>Translated_237_residues
MEQHINGKVVAITGGFGHLGIATAAWLGARGARVALIGRGAAPDSNALPDVPATALRLGGIDLVDPQAAVHALDAVHRQF
GGVDALLNIAGAFVWQTIADGDVDTWDRMYALNVKTALNASKAALPYLLQSAAGRIVNIGAGAASKAGTGMGAYAAAKAG
VARLTEALAAELLDRGITVNAVLPSIIDTPSNRADMPDADFTRWVQPQQIAATIGFLLSPEAQAISGASIPVSGRVA
>Mature_237_residues
MEQHINGKVVAITGGFGHLGIATAAWLGARGARVALIGRGAAPDSNALPDVPATALRLGGIDLVDPQAAVHALDAVHRQF
GGVDALLNIAGAFVWQTIADGDVDTWDRMYALNVKTALNASKAALPYLLQSAAGRIVNIGAGAASKAGTGMGAYAAAKAG
VARLTEALAAELLDRGITVNAVLPSIIDTPSNRADMPDADFTRWVQPQQIAATIGFLLSPEAQAISGASIPVSGRVA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=27.3469387755102, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=27.8884462151394, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=28.1632653061224, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI40254992, Length=233, Percent_Identity=25.7510729613734, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=26.7206477732794, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4503817, Length=220, Percent_Identity=24.5454545454545, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI15277342, Length=141, Percent_Identity=32.6241134751773, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI119392083, Length=192, Percent_Identity=32.2916666666667, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=29.8969072164948, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=31.25, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788459, Length=178, Percent_Identity=33.7078651685393, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=28.1746031746032, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367365, Length=238, Percent_Identity=29.8319327731092, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789208, Length=243, Percent_Identity=27.1604938271605, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=25.7142857142857, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=26.2295081967213, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=28.2258064516129, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=26, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=28.8, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=195, Percent_Identity=31.2820512820513, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=24.901185770751, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=27.3076923076923, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=231, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=194, Percent_Identity=28.8659793814433, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=28.2527881040892, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=199, Percent_Identity=29.1457286432161, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=237, Percent_Identity=28.2700421940928, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=244, Percent_Identity=27.8688524590164, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=25.296442687747, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=238, Percent_Identity=25.2100840336134, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=217, Percent_Identity=26.7281105990783, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=220, Percent_Identity=29.0909090909091, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=195, Percent_Identity=26.1538461538462, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=26.615969581749, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=240, Percent_Identity=28.75, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=208, Percent_Identity=29.8076923076923, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=194, Percent_Identity=28.3505154639175, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=197, Percent_Identity=26.9035532994924, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=190, Percent_Identity=26.8421052631579, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=225, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=25.4098360655738, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=221, Percent_Identity=27.1493212669683, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=241, Percent_Identity=26.9709543568465, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=205, Percent_Identity=27.3170731707317, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=187, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=30.1204819277108, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571526, Length=245, Percent_Identity=27.3469387755102, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=27.3469387755102, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=28.4, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=26.953125, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24639444, Length=240, Percent_Identity=28.3333333333333, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357673, Length=238, Percent_Identity=27.7310924369748, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24643142, Length=238, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=31.0756972111554, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355631, Length=174, Percent_Identity=27.0114942528736, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356301, Length=229, Percent_Identity=23.5807860262009, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24089; Mature: 24089

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQHINGKVVAITGGFGHLGIATAAWLGARGARVALIGRGAAPDSNALPDVPATALRLGG
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCC
IDLVDPQAAVHALDAVHRQFGGVDALLNIAGAFVWQTIADGDVDTWDRMYALNVKTALNA
CCEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEHHHHHCC
SKAALPYLLQSAAGRIVNIGAGAASKAGTGMGAYAAAKAGVARLTEALAAELLDRGITVN
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
AVLPSIIDTPSNRADMPDADFTRWVQPQQIAATIGFLLSPEAQAISGASIPVSGRVA
HHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEQHINGKVVAITGGFGHLGIATAAWLGARGARVALIGRGAAPDSNALPDVPATALRLGG
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCC
IDLVDPQAAVHALDAVHRQFGGVDALLNIAGAFVWQTIADGDVDTWDRMYALNVKTALNA
CCEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEHHHHHCC
SKAALPYLLQSAAGRIVNIGAGAASKAGTGMGAYAAAKAGVARLTEALAAELLDRGITVN
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
AVLPSIIDTPSNRADMPDADFTRWVQPQQIAATIGFLLSPEAQAISGASIPVSGRVA
HHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]