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The map label for this gene is chaA [C]

Identifier: 189353145

GI number: 189353145

Start: 1343094

End: 1344182

Strand: Direct

Name: chaA [C]

Synonym: BMULJ_04381

Alternate gene names: 189353145

Gene position: 1343094-1344182 (Clockwise)

Preceding gene: 189353139

Following gene: 189353147

Centisome position: 54.31

GC content: 69.24

Gene sequence:

>1089_bases
ATGCCGATCTCGTCCAACCAGCTTCCACGCTGGACCCTCTGGGCCCCGCTTGCCGCCTGGCTGGTACTCGCGCTGTCGCG
CGTCGTGCCGGCCGAAGGCCTCGTCATCGCGCTGTTCGCCGCCGCACTCGCGGGCGCCGTGTTCGCCGCCGTTCACCATG
CCGAAGTGGTCGCGCATCGCGTCGGCGAGCCGTTCGGCACGCTCGTGCTCGCGGTCGCCGTGACGGTCATCGAAGTCGCG
CTGATCGTGTCCGTGATGCTCGGCGCCGGCCCCGAGAAATCGGGCCTCGCGCGCGATACCGTGTTCGCCGCCGTGATGAT
CATCTGCAACGGCATCGTCGGGCTGTGTCTGCTCGTCGGCGCGTGGAAGCACGGCGAACAGGACTTTCAGGGGCGCGGCG
CGAGCAAGGCGCTCGCGGTGCTCGCCTCGTTGTCGGTGTTGTCGCTCGTGATGCCGAACTACCTGAGCGCGGCGCCCGGC
CCGATGCTGTCGAAGTCGCAGCTCGCGTTCGCCGGCGTGTCGTCGCTCGTGCTGTACGGCGTGTTCGTGTTCGTGCAGAC
GGTGCGCCATCGCGACTACTTCCTCGCCGATCACGACAGCGCGAACGAGGCCGTGCATGCGGCGCCGCCGAGCGGCCGCA
CCGCGCTGATCAGCCTCGCGCTGCTGTTCGCGAGCCTCGTCGCGGTCGTGCTGCTCGCGAAGCTGCTGTCGCCGGCCGTC
GAACATGCCGTGATGAAGCTCGGCGCGCCGGAAGCGGCGGTCGGGATCGTGATCGCCGCGCTCGTGCTGCTGCCCGAAGG
GCTCGCGGCCGTGACGGCCGCGCGCGCGAACCGGCTGCAGACCAGCATGAATCTCGCGCTCGGTTCCGCGCTCGCGAGTA
TCGGGCTCACGATCCCGACGGTCGCGGCCGTGTTCATCTGGGTCGGCCAGCCGCTGACGCTCGGCATCGGTCCGATGGAA
ACCGTGCTGCTGGCGCTCACGCTGCTCGTCAGCACGCTGACACTGAGCCAGGGTCGCACGACCGTGCTGCACGGCGTCGT
GCATCTGTCGCTGTTCGCCGCGTATCTGTTTCTGTCGGTCACGCATTGA

Upstream 100 bases:

>100_bases
TCCTTCAGCTGCATCGTTCTCGTTCGGCGGATTGTCCGGCCGGGCTTCGTCAACCCGTGTCGACGCATCGCGCGTCGCCA
CTCGAATAAGGAAACCCTCC

Downstream 100 bases:

>100_bases
CCTGTCGCCGGGCCTGGCCGCGCGTCGATTCCGGCGTGCGGCCAGGCCTGCGCTCCGCCCCTTTCCCCTCGCCTTTTCGT
TTTGAGCCTTCCCGCGTCGC

Product: Ca2+:H+ antiporter

Products: Na (I) [Periplasm]; Ca (II) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MPISSNQLPRWTLWAPLAAWLVLALSRVVPAEGLVIALFAAALAGAVFAAVHHAEVVAHRVGEPFGTLVLAVAVTVIEVA
LIVSVMLGAGPEKSGLARDTVFAAVMIICNGIVGLCLLVGAWKHGEQDFQGRGASKALAVLASLSVLSLVMPNYLSAAPG
PMLSKSQLAFAGVSSLVLYGVFVFVQTVRHRDYFLADHDSANEAVHAAPPSGRTALISLALLFASLVAVVLLAKLLSPAV
EHAVMKLGAPEAAVGIVIAALVLLPEGLAAVTAARANRLQTSMNLALGSALASIGLTIPTVAAVFIWVGQPLTLGIGPME
TVLLALTLLVSTLTLSQGRTTVLHGVVHLSLFAAYLFLSVTH

Sequences:

>Translated_362_residues
MPISSNQLPRWTLWAPLAAWLVLALSRVVPAEGLVIALFAAALAGAVFAAVHHAEVVAHRVGEPFGTLVLAVAVTVIEVA
LIVSVMLGAGPEKSGLARDTVFAAVMIICNGIVGLCLLVGAWKHGEQDFQGRGASKALAVLASLSVLSLVMPNYLSAAPG
PMLSKSQLAFAGVSSLVLYGVFVFVQTVRHRDYFLADHDSANEAVHAAPPSGRTALISLALLFASLVAVVLLAKLLSPAV
EHAVMKLGAPEAAVGIVIAALVLLPEGLAAVTAARANRLQTSMNLALGSALASIGLTIPTVAAVFIWVGQPLTLGIGPME
TVLLALTLLVSTLTLSQGRTTVLHGVVHLSLFAAYLFLSVTH
>Mature_361_residues
PISSNQLPRWTLWAPLAAWLVLALSRVVPAEGLVIALFAAALAGAVFAAVHHAEVVAHRVGEPFGTLVLAVAVTVIEVAL
IVSVMLGAGPEKSGLARDTVFAAVMIICNGIVGLCLLVGAWKHGEQDFQGRGASKALAVLASLSVLSLVMPNYLSAAPGP
MLSKSQLAFAGVSSLVLYGVFVFVQTVRHRDYFLADHDSANEAVHAAPPSGRTALISLALLFASLVAVVLLAKLLSPAVE
HAVMKLGAPEAAVGIVIAALVLLPEGLAAVTAARANRLQTSMNLALGSALASIGLTIPTVAAVFIWVGQPLTLGIGPMET
VLLALTLLVSTLTLSQGRTTVLHGVVHLSLFAAYLFLSVTH

Specific function: Possible cation transporter [H]

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1787468, Length=353, Percent_Identity=36.2606232294618, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 37329; Mature: 37198

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPISSNQLPRWTLWAPLAAWLVLALSRVVPAEGLVIALFAAALAGAVFAAVHHAEVVAHR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGEPFGTLVLAVAVTVIEVALIVSVMLGAGPEKSGLARDTVFAAVMIICNGIVGLCLLVG
HCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AWKHGEQDFQGRGASKALAVLASLSVLSLVMPNYLSAAPGPMLSKSQLAFAGVSSLVLYG
HHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
VFVFVQTVRHRDYFLADHDSANEAVHAAPPSGRTALISLALLFASLVAVVLLAKLLSPAV
HHHHHHHHHHCCCEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHAVMKLGAPEAAVGIVIAALVLLPEGLAAVTAARANRLQTSMNLALGSALASIGLTIPT
HHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VAAVFIWVGQPLTLGIGPMETVLLALTLLVSTLTLSQGRTTVLHGVVHLSLFAAYLFLSV
HHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
TH
CC
>Mature Secondary Structure 
PISSNQLPRWTLWAPLAAWLVLALSRVVPAEGLVIALFAAALAGAVFAAVHHAEVVAHR
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGEPFGTLVLAVAVTVIEVALIVSVMLGAGPEKSGLARDTVFAAVMIICNGIVGLCLLVG
HCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AWKHGEQDFQGRGASKALAVLASLSVLSLVMPNYLSAAPGPMLSKSQLAFAGVSSLVLYG
HHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
VFVFVQTVRHRDYFLADHDSANEAVHAAPPSGRTALISLALLFASLVAVVLLAKLLSPAV
HHHHHHHHHHCCCEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHAVMKLGAPEAAVGIVIAALVLLPEGLAAVTAARANRLQTSMNLALGSALASIGLTIPT
HHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VAAVFIWVGQPLTLGIGPMETVLLALTLLVSTLTLSQGRTTVLHGVVHLSLFAAYLFLSV
HHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
TH
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm]; Ca (II) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + Proton [Periplasm] = Proton [Cytoplasm] + Na (I) [Periplasm] Ca (II) [Cytoplasm] + Proton [Periplasm] = Ca (II) [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]