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The map label for this gene is bvgS [H]

Identifier: 189353027

GI number: 189353027

Start: 1195106

End: 1197070

Strand: Direct

Name: bvgS [H]

Synonym: BMULJ_04261

Alternate gene names: 189353027

Gene position: 1195106-1197070 (Clockwise)

Preceding gene: 189353025

Following gene: 189353028

Centisome position: 48.32

GC content: 72.06

Gene sequence:

>1965_bases
ATGAGGACCGTTACCCGTGAACTATTCCGGCAGGGTGCCTGGGTCGTGCTGGCCGTCGGCGTCGCGTGCGCGCTGCAGGC
CGGCGCGATTCGCGTGGTCGGCGCGCATGCGCCGTTTGCACCGTTGCCTTTTTATGCCGGCGTCGCCGCTGCCGCGTGGC
TGACGTCGCTTGCCGGCGGGCTGGCCGCGACTGCCGCGAGCACCGTCGTGATCGCCGCGCTCTGGTGGCGCGACGCGCCC
ACGGCGACATGGCTGGCCGATGCCGGCACGTTCGTCGCGATCGGCGTAATCGAATGCGCGTTGATCGCGGCCGTCAGGCC
GTTGTTCGCGCGCACGCGTGCGGATGACGACGCAAACGACGCACGGCGGGAGCCGGCGGCTGCACCGCCGCCGCCGTCCG
AGGACGTGCTGTTACGCCGCGTGGTCGATGCGTCGCCCGATGCGATCGTCGGCGTCGACGGCGCGCGGCGGATCGTCAGC
TGGAACCGCGCGGCGCAGCGCATCTTCGGCGCCGACGCGGCGACGATGATCGGCCGCGACGTGACGACGCTGTTCGCGCC
GCGCTGGCTGCGGCGTCAGCCGGTGCCCGCGTCGATCGACGAAGTACACGCGCCGCTCGGACCGATCGACGTGCTCTGCA
TGCGGCAAGACGCACACTGTTTTCGCGCGACGTTTGCGGCATCGCCGATCGTCGATGCGAACGGGCATGTCGACGGGCTG
TCGATGACGCTGCGCGAGGCGCGCGAGCGCCGTCGCGACGAGCGGCGCGATCACCGGTCGTTGCGCGGCGCGCGCGACGC
ACGCGCGCAGGCCGACACGTCGAACCGGCTGAAGGACGAACTGCTCGCGACCGTGTCGCATGAATTGCGCACGCCGCTGA
ACGTGATCTACGGCTGGGTCGAGGTGCTGCGCAGCGTCGACGGACAGGGCTTCGCGCAGCAGGCGGTCGACGCGATCGAT
CGCAGCGCGCGTTCGCTCGCGCGGATGGTCGGCGATCTGCTCGATGCGTCGTCGCTCGCGACCGGCAAGCTGCGTCTGGA
GCGTACGCCGGTCGACGTCGCGCGCGTCGTGCACGACGCGGCGCGCGAGTTCGGCGCGCCCGCGCATGCGAAGGGCATCA
CGCTCGTCACCGAAGGCGCGGGCACGGCGTGCGTGATCTCGGCCGACGCGGAGCGGCTGCACCAGGTGCTGTCGAACCTG
CTGTCGAATGCGATCAAGTTCACGCCGAGCGGCGGACGCATCGTCGTGTCGCTCGCGCGCGTCGACGCGCACGTCCGCCT
GTCGGTCGCCGACACCGGGCAGGGGATGGCGCCCGAAGCGCTGCCGAACCTGTTCGATCCGTTCAATCGACCGGCCAATG
CGCCGGCATCGCCGCAGCGCGGCCTCGGGCTCGGCCTGTCGATCGTGCGCAACATCGCGGAGTTGCACGGCGGATCCGTG
GAAGCGGCCAGCGAAGGGCCCGGCCGCGGCCTGACCGTCACGGTCATGCTGCCGGCGGGCTGGGACGCGGACATGGCGGT
CGTTCCGCTCGGCACGGCGGACGGCGTGCCGGCGGCGGCACTCGAACACCAGCGCGTGCTCGTCGTCGACGACGAGCCGA
CCTCGCGTGCCAGCCTCTCGGCCGCGCTGCAGACGCTCGGCGCGCAGGTGTCGACCGCGCACTCGGGGCGCGACGCGCTC
GCGAGCATCGAACGCGATCCGCCGACCGTCGTGCTGTCGGACATCGCGATGCCGGACGGCGACGGATTCTGGCTGATCGA
GCGCGTGCGGCGGCTGCCCGGGCGCCACGCACGCATGCCGGTGGTCGCCGTGACCGCGCATGCGGGCGTCGCGGATCGAC
AGCGGGTGATGGCCGCGGGCTTCGACGCGTATCTGTGCAAGCCGGTCGACGTGCCGACGCTCGCGAGCGCGATCGACGAC
GTGACGGCCCGTCGCACGCGCGAGAAGGACGGGCCGGAACGGTAA

Upstream 100 bases:

>100_bases
GCTTGCCGCGTGTCGCTCGCCCGGCCCGTTCGACGGTATGCCGGACCGCCCGGGCGGCACGCCGCCGCGCGAAGGATGCC
GGCGCGAATGCAGGAACGCA

Downstream 100 bases:

>100_bases
TGCCGGCAGGCGCGGCCGGGCGGTCGCGCGCCGGCAGCGGAGGACGGGAGGACAACATGAACGAAACGAAACACGCGCCG
CGCGCGAATGCGCAGCCGGC

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MRTVTRELFRQGAWVVLAVGVACALQAGAIRVVGAHAPFAPLPFYAGVAAAAWLTSLAGGLAATAASTVVIAALWWRDAP
TATWLADAGTFVAIGVIECALIAAVRPLFARTRADDDANDARREPAAAPPPPSEDVLLRRVVDASPDAIVGVDGARRIVS
WNRAAQRIFGADAATMIGRDVTTLFAPRWLRRQPVPASIDEVHAPLGPIDVLCMRQDAHCFRATFAASPIVDANGHVDGL
SMTLREARERRRDERRDHRSLRGARDARAQADTSNRLKDELLATVSHELRTPLNVIYGWVEVLRSVDGQGFAQQAVDAID
RSARSLARMVGDLLDASSLATGKLRLERTPVDVARVVHDAAREFGAPAHAKGITLVTEGAGTACVISADAERLHQVLSNL
LSNAIKFTPSGGRIVVSLARVDAHVRLSVADTGQGMAPEALPNLFDPFNRPANAPASPQRGLGLGLSIVRNIAELHGGSV
EAASEGPGRGLTVTVMLPAGWDADMAVVPLGTADGVPAAALEHQRVLVVDDEPTSRASLSAALQTLGAQVSTAHSGRDAL
ASIERDPPTVVLSDIAMPDGDGFWLIERVRRLPGRHARMPVVAVTAHAGVADRQRVMAAGFDAYLCKPVDVPTLASAIDD
VTARRTREKDGPER

Sequences:

>Translated_654_residues
MRTVTRELFRQGAWVVLAVGVACALQAGAIRVVGAHAPFAPLPFYAGVAAAAWLTSLAGGLAATAASTVVIAALWWRDAP
TATWLADAGTFVAIGVIECALIAAVRPLFARTRADDDANDARREPAAAPPPPSEDVLLRRVVDASPDAIVGVDGARRIVS
WNRAAQRIFGADAATMIGRDVTTLFAPRWLRRQPVPASIDEVHAPLGPIDVLCMRQDAHCFRATFAASPIVDANGHVDGL
SMTLREARERRRDERRDHRSLRGARDARAQADTSNRLKDELLATVSHELRTPLNVIYGWVEVLRSVDGQGFAQQAVDAID
RSARSLARMVGDLLDASSLATGKLRLERTPVDVARVVHDAAREFGAPAHAKGITLVTEGAGTACVISADAERLHQVLSNL
LSNAIKFTPSGGRIVVSLARVDAHVRLSVADTGQGMAPEALPNLFDPFNRPANAPASPQRGLGLGLSIVRNIAELHGGSV
EAASEGPGRGLTVTVMLPAGWDADMAVVPLGTADGVPAAALEHQRVLVVDDEPTSRASLSAALQTLGAQVSTAHSGRDAL
ASIERDPPTVVLSDIAMPDGDGFWLIERVRRLPGRHARMPVVAVTAHAGVADRQRVMAAGFDAYLCKPVDVPTLASAIDD
VTARRTREKDGPER
>Mature_654_residues
MRTVTRELFRQGAWVVLAVGVACALQAGAIRVVGAHAPFAPLPFYAGVAAAAWLTSLAGGLAATAASTVVIAALWWRDAP
TATWLADAGTFVAIGVIECALIAAVRPLFARTRADDDANDARREPAAAPPPPSEDVLLRRVVDASPDAIVGVDGARRIVS
WNRAAQRIFGADAATMIGRDVTTLFAPRWLRRQPVPASIDEVHAPLGPIDVLCMRQDAHCFRATFAASPIVDANGHVDGL
SMTLREARERRRDERRDHRSLRGARDARAQADTSNRLKDELLATVSHELRTPLNVIYGWVEVLRSVDGQGFAQQAVDAID
RSARSLARMVGDLLDASSLATGKLRLERTPVDVARVVHDAAREFGAPAHAKGITLVTEGAGTACVISADAERLHQVLSNL
LSNAIKFTPSGGRIVVSLARVDAHVRLSVADTGQGMAPEALPNLFDPFNRPANAPASPQRGLGLGLSIVRNIAELHGGSV
EAASEGPGRGLTVTVMLPAGWDADMAVVPLGTADGVPAAALEHQRVLVVDDEPTSRASLSAALQTLGAQVSTAHSGRDAL
ASIERDPPTVVLSDIAMPDGDGFWLIERVRRLPGRHARMPVVAVTAHAGVADRQRVMAAGFDAYLCKPVDVPTLASAIDD
VTARRTREKDGPER

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=373, Percent_Identity=31.0991957104558, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI48994928, Length=519, Percent_Identity=27.9383429672447, Blast_Score=155, Evalue=9e-39,
Organism=Escherichia coli, GI87081816, Length=374, Percent_Identity=30.7486631016043, Blast_Score=119, Evalue=9e-28,
Organism=Escherichia coli, GI1788393, Length=237, Percent_Identity=32.4894514767932, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=32.3275862068966, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=33.59375, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786783, Length=221, Percent_Identity=33.4841628959276, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=30.9917355371901, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=33.9366515837104, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=29.7297297297297, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788549, Length=370, Percent_Identity=23.7837837837838, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1790861, Length=220, Percent_Identity=32.7272727272727, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=29.5154185022026, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1790346, Length=221, Percent_Identity=28.0542986425339, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1788279, Length=198, Percent_Identity=28.7878787878788, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1788905, Length=116, Percent_Identity=36.2068965517241, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=36.036036036036, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=28.6995515695067, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787375, Length=122, Percent_Identity=29.5081967213115, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69241; Mature: 69241

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTVTRELFRQGAWVVLAVGVACALQAGAIRVVGAHAPFAPLPFYAGVAAAAWLTSLAGG
CCCHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LAATAASTVVIAALWWRDAPTATWLADAGTFVAIGVIECALIAAVRPLFARTRADDDAND
HHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
ARREPAAAPPPPSEDVLLRRVVDASPDAIVGVDGARRIVSWNRAAQRIFGADAATMIGRD
HHCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHCCH
VTTLFAPRWLRRQPVPASIDEVHAPLGPIDVLCMRQDAHCFRATFAASPIVDANGHVDGL
HHHHHCCHHHHCCCCCCCHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCHH
SMTLREARERRRDERRDHRSLRGARDARAQADTSNRLKDELLATVSHELRTPLNVIYGWV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVLRSVDGQGFAQQAVDAIDRSARSLARMVGDLLDASSLATGKLRLERTPVDVARVVHDA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHH
AREFGAPAHAKGITLVTEGAGTACVISADAERLHQVLSNLLSNAIKFTPSGGRIVVSLAR
HHHHCCCCCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHEEECCCCCEEEEEEEE
VDAHVRLSVADTGQGMAPEALPNLFDPFNRPANAPASPQRGLGLGLSIVRNIAELHGGSV
CCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCE
EAASEGPGRGLTVTVMLPAGWDADMAVVPLGTADGVPAAALEHQRVLVVDDEPTSRASLS
EECCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCHHHHCCCEEEEECCCCCCHHHHH
AALQTLGAQVSTAHSGRDALASIERDPPTVVLSDIAMPDGDGFWLIERVRRLPGRHARMP
HHHHHHCCHHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCC
VVAVTAHAGVADRQRVMAAGFDAYLCKPVDVPTLASAIDDVTARRTREKDGPER
EEEEEECCCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRTVTRELFRQGAWVVLAVGVACALQAGAIRVVGAHAPFAPLPFYAGVAAAAWLTSLAGG
CCCHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LAATAASTVVIAALWWRDAPTATWLADAGTFVAIGVIECALIAAVRPLFARTRADDDAND
HHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
ARREPAAAPPPPSEDVLLRRVVDASPDAIVGVDGARRIVSWNRAAQRIFGADAATMIGRD
HHCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHCCH
VTTLFAPRWLRRQPVPASIDEVHAPLGPIDVLCMRQDAHCFRATFAASPIVDANGHVDGL
HHHHHCCHHHHCCCCCCCHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCHH
SMTLREARERRRDERRDHRSLRGARDARAQADTSNRLKDELLATVSHELRTPLNVIYGWV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVLRSVDGQGFAQQAVDAIDRSARSLARMVGDLLDASSLATGKLRLERTPVDVARVVHDA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHH
AREFGAPAHAKGITLVTEGAGTACVISADAERLHQVLSNLLSNAIKFTPSGGRIVVSLAR
HHHHCCCCCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHEEECCCCCEEEEEEEE
VDAHVRLSVADTGQGMAPEALPNLFDPFNRPANAPASPQRGLGLGLSIVRNIAELHGGSV
CCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCE
EAASEGPGRGLTVTVMLPAGWDADMAVVPLGTADGVPAAALEHQRVLVVDDEPTSRASLS
EECCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCHHHHCCCEEEEECCCCCCHHHHH
AALQTLGAQVSTAHSGRDALASIERDPPTVVLSDIAMPDGDGFWLIERVRRLPGRHARMP
HHHHHHCCHHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCC
VVAVTAHAGVADRQRVMAAGFDAYLCKPVDVPTLASAIDDVTARRTREKDGPER
EEEEEECCCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]