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The map label for this gene is tcp [H]

Identifier: 189353025

GI number: 189353025

Start: 1191727

End: 1193526

Strand: Direct

Name: tcp [H]

Synonym: BMULJ_04259

Alternate gene names: 189353025

Gene position: 1191727-1193526 (Clockwise)

Preceding gene: 189353024

Following gene: 189353027

Centisome position: 48.19

GC content: 69.28

Gene sequence:

>1800_bases
ATGTTTTCGTCCATCCGCACCCGCATCCTCGCCGCGTGCGTCGCCATCGTCGTGTTCGCGCTCGTCGCCACCACCCTCAT
CAACTATTTCATTGCGCGCTCGTACAACAACGATGCGATCGATCGCAACCTGACGTCGGTGGCAAGGGGCCACGTGGTCG
GGATCGCGGACTGGGTCGCGACGCGGCGCCGGATGGTCGAGTCGCTGCAGGACGCCGCGCTGTCCGCCGATCCGCTGCCG
GTGTTCAAGCAGATGGCGGCCGCGGGCGGCTTCACGAACGTCTATGCGGGCTATGCGGACAAATCGTTCCGGTTTTCCGA
TCCGACCGGCATTCCCGCCGACTACGATCCGACCGGCCGGCCGTGGTACCGCCAGGCGGCGCAGGCCGGCAAGCCGGTGG
TCACGCCGCCGTACGTCGATGCGGGCACCGGCAACCTGGTCGTCACGTTCGCGGTGCCGATCCTGCGCGACGGTGCGCTG
AAGGGCGTCGTCGCGGCCGACGTCGGCATGGACAGCGTGATCGCGAACGTGAAGTCGATTCATCCGACGCCGGCGAGCTT
CGGGATGTTGATCGACAGCAGCGGCCACGTGGTCGCGCATCCCGACTCGAAGCTGACGCTGAAGCCGGTCGCCGACCTGT
CGCCCGATCTCGGTGCGATTCCCGCGGCGTCGCTCGCCGGTGCGAGCGCGCCGGTCGAGGTGCACGTCGGCGACGACGCG
AAGCTTGTGCGCGCGCAGCCGGTGCCGGGCACCGACTGGTACGCGCTCGTCGCGCTCGACAAGACCGATGCGACGGGCGG
CATGCGCTCGCTGCTGACCGCTTCGCTGATCACGATGATCGTGATCGTCGCGGTCGCGTCGTTGATCGTCGGCGCAATCA
CGACGACCGCGTTTCGCCGCCTCTCGCAGGTGCGGCTCGCGATGGCCGAGATCGGTTCGGGCGGCGGCGATCTGACGCAG
CGGCTGCCGGCCGACGGCCGCGACGAAGTGGCCGACATCGCGCGCTCGTTCAACCGTTTCGTCGACAAGCTCAGCGACGT
GATCCGGCAGATTCGCGATGCGAGCGAATCGGTGCGCACGGCGGCGAACGAGATCGCGGCGGGCAATCAGGATCTGTCGT
CGCGCACCGAATCGGCGGCCGCGAGCCTCGAGGAAACGGCCGCGTCGATGGAGCAGATCACCGCGACGGTCGGCCAGTCG
GCGGCCGCAGCCGGCCAAGCGGACGAGCGCGCGGCCGCCGCGTCGCGCATCGCGTCGCACGGCGGCGCGGTCGTGTCGGA
CGTCGTCGCGACGATGGCGAAGATCGAGGAAGCGTCGGGCCGGATCGGCGACATCATCGGCGTGATCGACGGCATCGCGT
TCCAGACCAACATCCTCGCGCTGAACGCGGCCGTCGAAGCGGCACGCGCGGGCGAGCAGGGGCGCGGCTTCGCGGTCGTC
GCGCAGGAAGTGCGCAGTCTCGCGCAGCGCAGCGCGCAGGCCGCGCGCGAAGTGAAGGTGCTCGTCGAATCGACGGTCGA
CAGCGTGTCGGCCGGCTCCGGGCAGGTGCGGCAGGCGGGCGAGACGATGCGCGAGATCGTGTCGAACGTCGCCAACGTGA
CGACGATCATCTCCGAGATCACGCATGCCGCGAACGAACAGACGCGCGGCATCCAGGAAGTGAACCGCGCGGTGACGCAG
CTCGACGAGATGGTTCAGCAGAACGCGGCGCTGGTCGAACAGTCGACCGCGGCGGCGTCGGCGCTGCAGACGCAGGCGAA
CGCGCTCGCGTCGACGGTCGGCCAGTTCAGGGTCGCGTAA

Upstream 100 bases:

>100_bases
TCATCGATTTGTCACGAACCCCTCAAGTCGGCGACGCGCGTGCCGTTTACCCGGTGAATCCCTCCACCGGGCGTTTGTGC
ACCCTTACCGAGTCGTCGCC

Downstream 100 bases:

>100_bases
CGCGCTCGCCGGACGCCGGGCGCGCGGCGTCGTCGCCGGCCTCGCGCATCAGCGCGAGCCGGTTGTAGAGCGTCTTCAGG
CTGATGCCGAGCGCCTTCGC

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MFSSIRTRILAACVAIVVFALVATTLINYFIARSYNNDAIDRNLTSVARGHVVGIADWVATRRRMVESLQDAALSADPLP
VFKQMAAAGGFTNVYAGYADKSFRFSDPTGIPADYDPTGRPWYRQAAQAGKPVVTPPYVDAGTGNLVVTFAVPILRDGAL
KGVVAADVGMDSVIANVKSIHPTPASFGMLIDSSGHVVAHPDSKLTLKPVADLSPDLGAIPAASLAGASAPVEVHVGDDA
KLVRAQPVPGTDWYALVALDKTDATGGMRSLLTASLITMIVIVAVASLIVGAITTTAFRRLSQVRLAMAEIGSGGGDLTQ
RLPADGRDEVADIARSFNRFVDKLSDVIRQIRDASESVRTAANEIAAGNQDLSSRTESAAASLEETAASMEQITATVGQS
AAAAGQADERAAAASRIASHGGAVVSDVVATMAKIEEASGRIGDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVV
AQEVRSLAQRSAQAAREVKVLVESTVDSVSAGSGQVRQAGETMREIVSNVANVTTIISEITHAANEQTRGIQEVNRAVTQ
LDEMVQQNAALVEQSTAAASALQTQANALASTVGQFRVA

Sequences:

>Translated_599_residues
MFSSIRTRILAACVAIVVFALVATTLINYFIARSYNNDAIDRNLTSVARGHVVGIADWVATRRRMVESLQDAALSADPLP
VFKQMAAAGGFTNVYAGYADKSFRFSDPTGIPADYDPTGRPWYRQAAQAGKPVVTPPYVDAGTGNLVVTFAVPILRDGAL
KGVVAADVGMDSVIANVKSIHPTPASFGMLIDSSGHVVAHPDSKLTLKPVADLSPDLGAIPAASLAGASAPVEVHVGDDA
KLVRAQPVPGTDWYALVALDKTDATGGMRSLLTASLITMIVIVAVASLIVGAITTTAFRRLSQVRLAMAEIGSGGGDLTQ
RLPADGRDEVADIARSFNRFVDKLSDVIRQIRDASESVRTAANEIAAGNQDLSSRTESAAASLEETAASMEQITATVGQS
AAAAGQADERAAAASRIASHGGAVVSDVVATMAKIEEASGRIGDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVV
AQEVRSLAQRSAQAAREVKVLVESTVDSVSAGSGQVRQAGETMREIVSNVANVTTIISEITHAANEQTRGIQEVNRAVTQ
LDEMVQQNAALVEQSTAAASALQTQANALASTVGQFRVA
>Mature_599_residues
MFSSIRTRILAACVAIVVFALVATTLINYFIARSYNNDAIDRNLTSVARGHVVGIADWVATRRRMVESLQDAALSADPLP
VFKQMAAAGGFTNVYAGYADKSFRFSDPTGIPADYDPTGRPWYRQAAQAGKPVVTPPYVDAGTGNLVVTFAVPILRDGAL
KGVVAADVGMDSVIANVKSIHPTPASFGMLIDSSGHVVAHPDSKLTLKPVADLSPDLGAIPAASLAGASAPVEVHVGDDA
KLVRAQPVPGTDWYALVALDKTDATGGMRSLLTASLITMIVIVAVASLIVGAITTTAFRRLSQVRLAMAEIGSGGGDLTQ
RLPADGRDEVADIARSFNRFVDKLSDVIRQIRDASESVRTAANEIAAGNQDLSSRTESAAASLEETAASMEQITATVGQS
AAAAGQADERAAAASRIASHGGAVVSDVVATMAKIEEASGRIGDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVV
AQEVRSLAQRSAQAAREVKVLVESTVDSVSAGSGQVRQAGETMREIVSNVANVTTIISEITHAANEQTRGIQEVNRAVTQ
LDEMVQQNAALVEQSTAAASALQTQANALASTVGQFRVA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=285, Percent_Identity=57.1929824561403, Blast_Score=277, Evalue=1e-75,
Organism=Escherichia coli, GI2367378, Length=331, Percent_Identity=52.5679758308157, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI1788194, Length=326, Percent_Identity=50, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1787690, Length=319, Percent_Identity=48.58934169279, Blast_Score=254, Evalue=8e-69,
Organism=Escherichia coli, GI1789453, Length=326, Percent_Identity=37.4233128834356, Blast_Score=200, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 62167; Mature: 62167

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSSIRTRILAACVAIVVFALVATTLINYFIARSYNNDAIDRNLTSVARGHVVGIADWVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHH
TRRRMVESLQDAALSADPLPVFKQMAAAGGFTNVYAGYADKSFRFSDPTGIPADYDPTGR
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
PWYRQAAQAGKPVVTPPYVDAGTGNLVVTFAVPILRDGALKGVVAADVGMDSVIANVKSI
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCCHHHHHCCHHHHHHHHHHC
HPTPASFGMLIDSSGHVVAHPDSKLTLKPVADLSPDLGAIPAASLAGASAPVEVHVGDDA
CCCCCCCCEEEECCCCEEECCCCCEEECCHHCCCCCCCCCCCHHHCCCCCCEEEEECCCC
KLVRAQPVPGTDWYALVALDKTDATGGMRSLLTASLITMIVIVAVASLIVGAITTTAFRR
EEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQVRLAMAEIGSGGGDLTQRLPADGRDEVADIARSFNRFVDKLSDVIRQIRDASESVRT
HHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AANEIAAGNQDLSSRTESAAASLEETAASMEQITATVGQSAAAAGQADERAAAASRIASH
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHC
GGAVVSDVVATMAKIEEASGRIGDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVV
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
AQEVRSLAQRSAQAAREVKVLVESTVDSVSAGSGQVRQAGETMREIVSNVANVTTIISEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
THAANEQTRGIQEVNRAVTQLDEMVQQNAALVEQSTAAASALQTQANALASTVGQFRVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFSSIRTRILAACVAIVVFALVATTLINYFIARSYNNDAIDRNLTSVARGHVVGIADWVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHH
TRRRMVESLQDAALSADPLPVFKQMAAAGGFTNVYAGYADKSFRFSDPTGIPADYDPTGR
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
PWYRQAAQAGKPVVTPPYVDAGTGNLVVTFAVPILRDGALKGVVAADVGMDSVIANVKSI
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCCHHHHHCCHHHHHHHHHHC
HPTPASFGMLIDSSGHVVAHPDSKLTLKPVADLSPDLGAIPAASLAGASAPVEVHVGDDA
CCCCCCCCEEEECCCCEEECCCCCEEECCHHCCCCCCCCCCCHHHCCCCCCEEEEECCCC
KLVRAQPVPGTDWYALVALDKTDATGGMRSLLTASLITMIVIVAVASLIVGAITTTAFRR
EEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQVRLAMAEIGSGGGDLTQRLPADGRDEVADIARSFNRFVDKLSDVIRQIRDASESVRT
HHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AANEIAAGNQDLSSRTESAAASLEETAASMEQITATVGQSAAAAGQADERAAAASRIASH
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHC
GGAVVSDVVATMAKIEEASGRIGDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVV
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
AQEVRSLAQRSAQAAREVKVLVESTVDSVSAGSGQVRQAGETMREIVSNVANVTTIISEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
THAANEQTRGIQEVNRAVTQLDEMVQQNAALVEQSTAAASALQTQANALASTVGQFRVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]