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The map label for this gene is ampC [H]

Identifier: 189352969

GI number: 189352969

Start: 1128386

End: 1129345

Strand: Direct

Name: ampC [H]

Synonym: BMULJ_04203

Alternate gene names: 189352969

Gene position: 1128386-1129345 (Clockwise)

Preceding gene: 189352967

Following gene: 189352970

Centisome position: 45.63

GC content: 66.56

Gene sequence:

>960_bases
ATGGCCAAAGCATTCGCCTCCCAAGCCGATCTGGAAGAGAAGAAGATCACCTGGACGCAGCTGTCCGAGAACGCGTACGC
GTACACCGCCGAAGGCGACCCGAACTCGGGCGTGATCATCGGCGACGACAGCGTGCTGATCGTCGATACGACCGCGACGC
CCGCGATGGCGCAGGATCTGATCGCGAAGATCCGCAGCGTGACCGACAAGCCGATCAAGCACGTCGTGCTGTCGCACTAC
CACGCCGTGCGCGTGCTCGGCGCGTCGGCGTACTTCGCGGAAGGCGCGCAGCACGTGATCGCGAGCCGCGGCACGTACGA
GATGATCGTCGAGCGCGGCGAGGCCGACATGAAGTCGGAGATCGAGCGCTTTCCGCGCCTGTTCGCGGGCGTCGAGACGG
TGCCGGGGCTGACCTGGCCGACGCTCGTGTTCGAGCGCGAGATCACGCTGTTCCTCGGCAAGCTCGAGGTGAAGATCATG
CACGTCGGCTCGGGCCATACGAAGGGCGACACGATCGTCTGGCTGCCGTCGCAGAAGGTGCTGTTCTCGGGCGACCTCGT
CGAATACGACGCCGCGTGCTACTGCGGCGACGCGCAGCTCGAGCAGTGGCCGGCCACGCTCGAAGCGCTGCGCGCGCTCG
GCGCCGAGAAGCTCGTGCCGGGCCGCGGCCCCGCGCTGCTGAATCCGGCGGAAGTGAACCGGGGTCTCGACTACACGAAG
GACTTCGTGACCACGCTGCTCGCGCAGGGCCGCAAGGCGGTCGAGCGCAAACTCGATCTGAAGGCCGCGATGGCGCTCAC
GCGCGAAGCGATGGATCCGAAGTTCGGCCACGTGTTCATCTACGAGCACTGCCTGCCGTTCGACGTGTCGCGCGCATTCG
ACGAAGCGAGCGGCATCACGCATCCGCGCATCTGGACCGCGGAGCGCGACAAGGAAATGTGGGCCGCCCTGCAGGACTGA

Upstream 100 bases:

>100_bases
TTAGACAATAGCAAGCGACTTTGTCATTGACAAATAATCGGCGCAAGACGATGATCGGCGCATTCCCCTCAACACATGGC
TCGCAGCCACGGAACGCAAC

Downstream 100 bases:

>100_bases
GCGGCCTCCGGCGGCGCGTCGCGCCGCCGCCTTGCCGCGATGCGGTCCGGCCGCCGCGCAGCGCGACGGTCCGCACGGCC
TGACCCGCTCTCATAGAAAG

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MAKAFASQADLEEKKITWTQLSENAYAYTAEGDPNSGVIIGDDSVLIVDTTATPAMAQDLIAKIRSVTDKPIKHVVLSHY
HAVRVLGASAYFAEGAQHVIASRGTYEMIVERGEADMKSEIERFPRLFAGVETVPGLTWPTLVFEREITLFLGKLEVKIM
HVGSGHTKGDTIVWLPSQKVLFSGDLVEYDAACYCGDAQLEQWPATLEALRALGAEKLVPGRGPALLNPAEVNRGLDYTK
DFVTTLLAQGRKAVERKLDLKAAMALTREAMDPKFGHVFIYEHCLPFDVSRAFDEASGITHPRIWTAERDKEMWAALQD

Sequences:

>Translated_319_residues
MAKAFASQADLEEKKITWTQLSENAYAYTAEGDPNSGVIIGDDSVLIVDTTATPAMAQDLIAKIRSVTDKPIKHVVLSHY
HAVRVLGASAYFAEGAQHVIASRGTYEMIVERGEADMKSEIERFPRLFAGVETVPGLTWPTLVFEREITLFLGKLEVKIM
HVGSGHTKGDTIVWLPSQKVLFSGDLVEYDAACYCGDAQLEQWPATLEALRALGAEKLVPGRGPALLNPAEVNRGLDYTK
DFVTTLLAQGRKAVERKLDLKAAMALTREAMDPKFGHVFIYEHCLPFDVSRAFDEASGITHPRIWTAERDKEMWAALQD
>Mature_318_residues
AKAFASQADLEEKKITWTQLSENAYAYTAEGDPNSGVIIGDDSVLIVDTTATPAMAQDLIAKIRSVTDKPIKHVVLSHYH
AVRVLGASAYFAEGAQHVIASRGTYEMIVERGEADMKSEIERFPRLFAGVETVPGLTWPTLVFEREITLFLGKLEVKIMH
VGSGHTKGDTIVWLPSQKVLFSGDLVEYDAACYCGDAQLEQWPATLEALRALGAEKLVPGRGPALLNPAEVNRGLDYTKD
FVTTLLAQGRKAVERKLDLKAAMALTREAMDPKFGHVFIYEHCLPFDVSRAFDEASGITHPRIWTAERDKEMWAALQD

Specific function: Can hydrolyze carbapenem compounds [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001018
- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 35223; Mature: 35091

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAFASQADLEEKKITWTQLSENAYAYTAEGDPNSGVIIGDDSVLIVDTTATPAMAQDL
CCCCCCCCCCCHHHCEEHEEECCCCEEEEECCCCCCCEEECCCCEEEEECCCCHHHHHHH
IAKIRSVTDKPIKHVVLSHYHAVRVLGASAYFAEGAQHVIASRGTYEMIVERGEADMKSE
HHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHH
IERFPRLFAGVETVPGLTWPTLVFEREITLFLGKLEVKIMHVGSGHTKGDTIVWLPSQKV
HHHHHHHHHCHHHCCCCCCHHHHHHHHHEEEEEEEEEEEEEECCCCCCCCEEEEECCCCE
LFSGDLVEYDAACYCGDAQLEQWPATLEALRALGAEKLVPGRGPALLNPAEVNRGLDYTK
EEECCEEEECCEEEECCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHCCCCHHH
DFVTTLLAQGRKAVERKLDLKAAMALTREAMDPKFGHVFIYEHCLPFDVSRAFDEASGIT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCC
HPRIWTAERDKEMWAALQD
CCEEECCCCHHHHHHHCCC
>Mature Secondary Structure 
AKAFASQADLEEKKITWTQLSENAYAYTAEGDPNSGVIIGDDSVLIVDTTATPAMAQDL
CCCCCCCCCCHHHCEEHEEECCCCEEEEECCCCCCCEEECCCCEEEEECCCCHHHHHHH
IAKIRSVTDKPIKHVVLSHYHAVRVLGASAYFAEGAQHVIASRGTYEMIVERGEADMKSE
HHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHH
IERFPRLFAGVETVPGLTWPTLVFEREITLFLGKLEVKIMHVGSGHTKGDTIVWLPSQKV
HHHHHHHHHCHHHCCCCCCHHHHHHHHHEEEEEEEEEEEEEECCCCCCCCEEEEECCCCE
LFSGDLVEYDAACYCGDAQLEQWPATLEALRALGAEKLVPGRGPALLNPAEVNRGLDYTK
EEECCEEEECCEEEECCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHCCCCHHH
DFVTTLLAQGRKAVERKLDLKAAMALTREAMDPKFGHVFIYEHCLPFDVSRAFDEASGIT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCC
HPRIWTAERDKEMWAALQD
CCEEECCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1856163 [H]