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The map label for this gene is rhtB [H]

Identifier: 189352965

GI number: 189352965

Start: 1124697

End: 1125341

Strand: Reverse

Name: rhtB [H]

Synonym: BMULJ_04199

Alternate gene names: 189352965

Gene position: 1125341-1124697 (Counterclockwise)

Preceding gene: 189352968

Following gene: 189352964

Centisome position: 45.5

GC content: 70.54

Gene sequence:

>645_bases
ATGTCGTTCCAGCTTTACCTGTCGTTCGTCGCTGCTTCCGTCGTTCTCGTCTACGCCCCCGGCCCCGTCAACCTGCTCAC
GATGAACCAGGCGCTGCGCGCCGGCTGGCGTCGCGCGCTGCCGTGCGTCTGGGGCGGCACGCTCGCCGTGCTGCTGCAAC
TGGCGCTCACCGCGCTGTGCCTGAACTCGCTCGTCCATCTCGACGACCGCGCGCTCGCCGTGCTGCGCTGGGCCGGCGCC
GCCTATCTCGTCTGGCTCGGCGCGAAGCAATGGCTGAGCCGCACGCCGGCGAACGCCTCCGCCGCCAATGCGACCGCCGC
GGCCGACGCCGCGCCGCCCGACACCGATCGCGCGCTGTTCTGGCGCGGCGTCGCGACGTCCGGACTCAATCCGAAGACGC
TGCTGTTCTTCCCGTCGTTCTTTCCGCAATTCATCCACCCCGACGCCGGCTGGAGCCTCAACGCCCAGTACCTGCTGCTC
GCGACGACGTTCGCGCTGCTGTTCGCGGGCGGCGTCGCGTCGATGGCGCTGTTCTCGCACCGGCTCAGCCGCACCTTGCA
GCGACCCGCGCGGATGCGCGCGATGAACCGCGTGACGGGCGGGCTGCTCGTCGGCATGGGCGCAATCATGGCCGGCTGGA
ACTGA

Upstream 100 bases:

>100_bases
ACGAGTTGCGGCGCCGGTCACGCAGGCATGCGAATGCCCGCCGCGCGCCCGTCCATCCGATCGGGCGCGCGGCGCCCGTC
CCGTTCCTGCGCTTCCTGTC

Downstream 100 bases:

>100_bases
GCGCCCGCGATCGCGCGACGCCGTTCGAAGATACGGTCCGCGCCGCCGGCAGCGCGCCCGGTACAATCGCGCGATGCCCG
AACTGCTCACCTACGGCGGC

Product: putative threonine efflux protein

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MSFQLYLSFVAASVVLVYAPGPVNLLTMNQALRAGWRRALPCVWGGTLAVLLQLALTALCLNSLVHLDDRALAVLRWAGA
AYLVWLGAKQWLSRTPANASAANATAAADAAPPDTDRALFWRGVATSGLNPKTLLFFPSFFPQFIHPDAGWSLNAQYLLL
ATTFALLFAGGVASMALFSHRLSRTLQRPARMRAMNRVTGGLLVGMGAIMAGWN

Sequences:

>Translated_214_residues
MSFQLYLSFVAASVVLVYAPGPVNLLTMNQALRAGWRRALPCVWGGTLAVLLQLALTALCLNSLVHLDDRALAVLRWAGA
AYLVWLGAKQWLSRTPANASAANATAAADAAPPDTDRALFWRGVATSGLNPKTLLFFPSFFPQFIHPDAGWSLNAQYLLL
ATTFALLFAGGVASMALFSHRLSRTLQRPARMRAMNRVTGGLLVGMGAIMAGWN
>Mature_213_residues
SFQLYLSFVAASVVLVYAPGPVNLLTMNQALRAGWRRALPCVWGGTLAVLLQLALTALCLNSLVHLDDRALAVLRWAGAA
YLVWLGAKQWLSRTPANASAANATAAADAAPPDTDRALFWRGVATSGLNPKTLLFFPSFFPQFIHPDAGWSLNAQYLLLA
TTFALLFAGGVASMALFSHRLSRTLQRPARMRAMNRVTGGLLVGMGAIMAGWN

Specific function: Conducts the efflux of homoserine and homoserine lactone [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=211, Percent_Identity=30.3317535545024, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23001; Mature: 22870

Theoretical pI: Translated: 11.56; Mature: 11.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFQLYLSFVAASVVLVYAPGPVNLLTMNQALRAGWRRALPCVWGGTLAVLLQLALTALC
CCHHHHHHHHHHHHEEEECCCCCEEEEHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHH
LNSLVHLDDRALAVLRWAGAAYLVWLGAKQWLSRTPANASAANATAAADAAPPDTDRALF
HHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEE
WRGVATSGLNPKTLLFFPSFFPQFIHPDAGWSLNAQYLLLATTFALLFAGGVASMALFSH
EECHHCCCCCCCEEEECHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLSRTLQRPARMRAMNRVTGGLLVGMGAIMAGWN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFQLYLSFVAASVVLVYAPGPVNLLTMNQALRAGWRRALPCVWGGTLAVLLQLALTALC
CHHHHHHHHHHHHEEEECCCCCEEEEHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHH
LNSLVHLDDRALAVLRWAGAAYLVWLGAKQWLSRTPANASAANATAAADAAPPDTDRALF
HHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEE
WRGVATSGLNPKTLLFFPSFFPQFIHPDAGWSLNAQYLLLATTFALLFAGGVASMALFSH
EECHHCCCCCCCEEEECHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLSRTLQRPARMRAMNRVTGGLLVGMGAIMAGWN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]