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The map label for this gene is kdgR [H]

Identifier: 189352749

GI number: 189352749

Start: 856519

End: 857340

Strand: Reverse

Name: kdgR [H]

Synonym: BMULJ_03981

Alternate gene names: 189352749

Gene position: 857340-856519 (Counterclockwise)

Preceding gene: 189352757

Following gene: 189352745

Centisome position: 34.67

GC content: 71.05

Gene sequence:

>822_bases
ATGCGCGATACGGCCCCCGCGCCGCCCGATGCGGCACCCGACGACGCGCGCGTGCTGCGCGCGCTCGCCGTCCTCGAAGC
GCTCGCGTCGGGCGGTCAGCCCTATACGCTGTCGCAGCTCGCCGCGCGCCTGCACATTCCGAAGGCGACGCTGCTGCGGC
TGATCGAATCGCTCGAAGCGCGCGGCTACGTGATCCACATGCCCGACTCGCGCGGCCACGATCGCGGCATCGCGCTCGGT
CCGCGCGCCGCGCAGTTCGCGCTCGCGGCGCTGTCGAACAACACGTTCACGCGCGGCTGCCGCTCGGTGCTGCGTTCGCT
CGTCGACGTGCTCGGCGAGACCTGCAACCTGACGGCCCTCGACGGCGACACCGTGCTGTATGTCGAACGCGTCGAAACGA
CCGAACCGCTGCGGCTCGAAATGCGGCCCGGCATGCGCGTGCCGCTGCATTGCACGGCGAGCGGCAAGCTGTTTCTGTCG
CAGATGAACGCGCTGGAGCGCAACGCGATGCTCGCGCGGCTCACGCTGAAGAAGATGACCTACCGGACGCTGACCGATAC
GCAACTGCTCGCGGCCGAGCTCGACCGGCTGTCGGTGCGCGGCGTCGGCATCGACAACGAGGAATTCGTGCGCGGGATGG
TGGCGGTCGCGGTGCCCGTGAAGGATGCGGCGAGCGGGCGCGTGCTCGCGGCGCTCGCCGTGCACGCGCCGACTGCGCGC
GCAACGCTCGCCGATCTGCTCGAGACGGTACCGAAGCTGAAGGATGCGGCGAGCCGGCTCGCGCCGCTGCTGCATGCGTC
CGACGCGGCGCAGCCCGCGTGA

Upstream 100 bases:

>100_bases
ATTGTCCACGCGGGGAATGTGGTACAAAAACCGTTCAATTCGTTTCATTTCTCACGTAGCACAGACGCGGGACGCACGAC
GATCCCGACGGAGGAGACAG

Downstream 100 bases:

>100_bases
GCGGGACACGGCCGCGCATGGCACGCGCCGCGCAGCCGCCATCAAGACACACGCGTCGCGCCGCGACGAGCGGCCGATCG
CGCGGCCGCGAATGCGGCTT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MRDTAPAPPDAAPDDARVLRALAVLEALASGGQPYTLSQLAARLHIPKATLLRLIESLEARGYVIHMPDSRGHDRGIALG
PRAAQFALAALSNNTFTRGCRSVLRSLVDVLGETCNLTALDGDTVLYVERVETTEPLRLEMRPGMRVPLHCTASGKLFLS
QMNALERNAMLARLTLKKMTYRTLTDTQLLAAELDRLSVRGVGIDNEEFVRGMVAVAVPVKDAASGRVLAALAVHAPTAR
ATLADLLETVPKLKDAASRLAPLLHASDAAQPA

Sequences:

>Translated_273_residues
MRDTAPAPPDAAPDDARVLRALAVLEALASGGQPYTLSQLAARLHIPKATLLRLIESLEARGYVIHMPDSRGHDRGIALG
PRAAQFALAALSNNTFTRGCRSVLRSLVDVLGETCNLTALDGDTVLYVERVETTEPLRLEMRPGMRVPLHCTASGKLFLS
QMNALERNAMLARLTLKKMTYRTLTDTQLLAAELDRLSVRGVGIDNEEFVRGMVAVAVPVKDAASGRVLAALAVHAPTAR
ATLADLLETVPKLKDAASRLAPLLHASDAAQPA
>Mature_273_residues
MRDTAPAPPDAAPDDARVLRALAVLEALASGGQPYTLSQLAARLHIPKATLLRLIESLEARGYVIHMPDSRGHDRGIALG
PRAAQFALAALSNNTFTRGCRSVLRSLVDVLGETCNLTALDGDTVLYVERVETTEPLRLEMRPGMRVPLHCTASGKLFLS
QMNALERNAMLARLTLKKMTYRTLTDTQLLAAELDRLSVRGVGIDNEEFVRGMVAVAVPVKDAASGRVLAALAVHAPTAR
ATLADLLETVPKLKDAASRLAPLLHASDAAQPA

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=265, Percent_Identity=31.6981132075472, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786468, Length=245, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI87082359, Length=225, Percent_Identity=27.1111111111111, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786715, Length=223, Percent_Identity=27.3542600896861, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790752, Length=218, Percent_Identity=27.0642201834862, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789999, Length=229, Percent_Identity=26.6375545851528, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788581, Length=215, Percent_Identity=26.9767441860465, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29221; Mature: 29221

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDTAPAPPDAAPDDARVLRALAVLEALASGGQPYTLSQLAARLHIPKATLLRLIESLEA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHH
RGYVIHMPDSRGHDRGIALGPRAAQFALAALSNNTFTRGCRSVLRSLVDVLGETCNLTAL
CCEEEECCCCCCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
DGDTVLYVERVETTEPLRLEMRPGMRVPLHCTASGKLFLSQMNALERNAMLARLTLKKMT
CCCEEEEEEECCCCCCEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YRTLTDTQLLAAELDRLSVRGVGIDNEEFVRGMVAVAVPVKDAASGRVLAALAVHAPTAR
HHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHEEEECCCCCCCCEEEEEECCCCCHH
ATLADLLETVPKLKDAASRLAPLLHASDAAQPA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRDTAPAPPDAAPDDARVLRALAVLEALASGGQPYTLSQLAARLHIPKATLLRLIESLEA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHH
RGYVIHMPDSRGHDRGIALGPRAAQFALAALSNNTFTRGCRSVLRSLVDVLGETCNLTAL
CCEEEECCCCCCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
DGDTVLYVERVETTEPLRLEMRPGMRVPLHCTASGKLFLSQMNALERNAMLARLTLKKMT
CCCEEEEEEECCCCCCEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YRTLTDTQLLAAELDRLSVRGVGIDNEEFVRGMVAVAVPVKDAASGRVLAALAVHAPTAR
HHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHEEEECCCCCCCCEEEEEECCCCCHH
ATLADLLETVPKLKDAASRLAPLLHASDAAQPA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]