Click here to switch to the map view.

The map label for this gene is lrp [H]

Identifier: 189352643

GI number: 189352643

Start: 730672

End: 731136

Strand: Direct

Name: lrp [H]

Synonym: BMULJ_03874

Alternate gene names: 189352643

Gene position: 730672-731136 (Clockwise)

Preceding gene: 189352642

Following gene: 189352644

Centisome position: 29.54

GC content: 64.73

Gene sequence:

>465_bases
ATGACCGACAAGAAGATGCAGCTCGACAAGATCGATCTCCGGATCCTCGACATCCTGCGCACCGACGGCCGGATTTCGTA
CCGGAAGCTGTCGGAGCTCGTGAATCTCACGCCGCGCCCGTGTCAGGCACGCGTGGAACGGCTCGAGGCGCTCGGCGTGA
TCGCGGGTTACCGCGCAGTGATCAACGCGCCGCGCGCGACCAAGCCGATCGTCGTGATCGCGCAGATCGTGCTGGCCGAT
CATGGGCGCTCGCAGGCGCCGTTCGAGGACGAGATGCGCGCGAATCCGGCCGTGCTCGATTGCTGGCTCGTCAGCGGCAC
GTTCGATTTCGTCGTGCGGATCGCGTGCGAGGATCTCGACGAATACCGCCGAATCGCGAATGCGTGGCTCGACAGCCCGC
GCTTCCGGATCGAGAAGATCGTGACGACGGCCGAGCTGCAGGCGATCAAGCGCAGCGTCGTTTGA

Upstream 100 bases:

>100_bases
TAGCCGATTGGCGCGCAGTCGCTTCGGCCGGATAATGTGGCCCGCGGAACCGGAGCACGCGTTCCGCGCACCAGCCACGA
CCCGACCGGAGCGAATGCGG

Downstream 100 bases:

>100_bases
CGCGACCGTGCGCGCCGCGCCGTCGTGCATGGAGCGCGCGGCGGGATGGAAGCGCGCCGGGTTCGATTCGACCAACCGGC
ATGATCATCGATCTGCATTC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MTDKKMQLDKIDLRILDILRTDGRISYRKLSELVNLTPRPCQARVERLEALGVIAGYRAVINAPRATKPIVVIAQIVLAD
HGRSQAPFEDEMRANPAVLDCWLVSGTFDFVVRIACEDLDEYRRIANAWLDSPRFRIEKIVTTAELQAIKRSVV

Sequences:

>Translated_154_residues
MTDKKMQLDKIDLRILDILRTDGRISYRKLSELVNLTPRPCQARVERLEALGVIAGYRAVINAPRATKPIVVIAQIVLAD
HGRSQAPFEDEMRANPAVLDCWLVSGTFDFVVRIACEDLDEYRRIANAWLDSPRFRIEKIVTTAELQAIKRSVV
>Mature_153_residues
TDKKMQLDKIDLRILDILRTDGRISYRKLSELVNLTPRPCQARVERLEALGVIAGYRAVINAPRATKPIVVIAQIVLADH
GRSQAPFEDEMRANPAVLDCWLVSGTFDFVVRIACEDLDEYRRIANAWLDSPRFRIEKIVTTAELQAIKRSVV

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=128, Percent_Identity=37.5, Blast_Score=80, Evalue=7e-17,
Organism=Escherichia coli, GI87081742, Length=126, Percent_Identity=31.7460317460317, Blast_Score=67, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17504; Mature: 17372

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKKMQLDKIDLRILDILRTDGRISYRKLSELVNLTPRPCQARVERLEALGVIAGYRAV
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
INAPRATKPIVVIAQIVLADHGRSQAPFEDEMRANPAVLDCWLVSGTFDFVVRIACEDLD
HCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCCCEEEEEECCCHHHHHHHHHHHHHH
EYRRIANAWLDSPRFRIEKIVTTAELQAIKRSVV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDKKMQLDKIDLRILDILRTDGRISYRKLSELVNLTPRPCQARVERLEALGVIAGYRAV
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
INAPRATKPIVVIAQIVLADHGRSQAPFEDEMRANPAVLDCWLVSGTFDFVVRIACEDLD
HCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCCCEEEEEECCCHHHHHHHHHHHHHH
EYRRIANAWLDSPRFRIEKIVTTAELQAIKRSVV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]