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The map label for this gene is rpoD [H]

Identifier: 189352484

GI number: 189352484

Start: 535029

End: 537443

Strand: Direct

Name: rpoD [H]

Synonym: BMULJ_03703

Alternate gene names: 189352484

Gene position: 535029-537443 (Clockwise)

Preceding gene: 189352483

Following gene: 189352486

Centisome position: 21.63

GC content: 63.35

Gene sequence:

>2415_bases
ATGGCAAAGACGACAGGCGGAAAGAAAGCAACGGGCAAGGGCTCGACGGAGCCGACCAAGAAGGTCACAGCGGCCAAGTC
TGCTTCTTCCGCCAGGACGACGTCTTCGGCTACATCAACCCCTGCAGGAAAGAAAACCGCGGCCGGCACTGCTCAAGCTG
CGCCGGCGCCGGCAGCCAGAACACGGGCTGCCGCCAGACCCGACTCCGGGCCGGCCAAGCCGGCGGCGAAGCGGGCAAGT
GCGAAAAGCGCAAGGGACGCGGCTGCCGCGGCGGACGAAACGGCAGTACGTACTACTCATGCACCCACGGTTCAACCGGC
TGTCGTCCAGCAGCCGCGAGTCGATATAGCCGGTACGGCGAACTCCATGACGAAAAAGCTGAACGAAGTATCCGTCGATG
ACGACGCAAATCAGAGCGACGAGCAGCCCGCAGCGGCGGCTGCCCCGGGCAAGTCCAAGGTGCGCGACCGCCGCGCCAAG
GAAAAGGCGCTGCTGAAGGAAGCGTTCGCGACGAGCACGCCCGGCACGGCCGAGGAGCTCGAAGAGCGCCGCGTGAAGCT
GCGCGCGCTGATCAAGCTCGGCAAGGAGCGGGGCTTCCTGACGTACGCCGAAATCAACGACCACCTGCCGGACAACTTCA
CCGAGACCGAAGCCCTCGAAGGCATCATCGGCACGTTCAACGATATGGGCGTGGCGGTTTACGAGCAGGCGCCGGACGCG
GAAACGCTGCTCCTGAACGACAACGCGCCGGCCGCGTCGTCGGACGACGAAGTCGAAGAGGAAGCGGAAGTTGCGCTGTC
CACCGTCGATTCCGAATTCGGCCGCACGACCGATCCGGTCCGGATGTACATGCGCGAGATGGGCACGGTCGAGCTGCTCA
CGCGCGAAGGCGAAATCGAGATCGCGAAGCGCATCGAAGACGGCCTGCGCCACATGGTGATGGCCATCTCCGCATGCCCG
ACGACGATCGCCGACATCCTCGCGATGGCGGAGCGCGTCGCGAACGACGAGATTCGCGTCGACGAGCTCGTCGACGGCCT
GCTCGATCCGAACGCTTCGGACACCGACACGGACGGTTTCTCCGCGAAGGAAGCGGAGGAAATCGAGAACGAGGACGAAG
AGGTCGAAGAGGAAGAGGAAGAAGAGGAAGAGGAGGACGATGACGGCGCCGCGCAGGCGACCGCCAACGCCGCCCAGCTC
GAAGCGCTGAAGCGCGCCTCGCTCGAGAAGTTCGCGCTGATCAGCGAGTGGTTCGACAAGATGCGCCGCGCGTTCGAGAA
GGAGGGCTACAAGTCGAAGTCCTACCTGAAGGCGCAGGAAACGATCCAGAGCGAGCTGATGACGATCCGCTTCACCGCGC
GTACCGTCGAGCGCCTCTGCGACACGCTGCGTGCGCAGGTGGATGAAGTGCGTCAGGTCGAGCGCCAGATCCTGCACATC
GTCGTCGACAAGTGCGGGATGCCGCGTTCGGAATTCATCGCGCGCTTCCCGGGCAACGAGACGGACCTCGACTGGGCCGA
GAAGATCGCGGCCGAAGGCCATTCGTACAGCGCGATCCTGTCGCGCAACATCCCGGCGATTCGCGAACAGCAGCAGCGTC
TGCTCGACCTGCAGGCGCGCGTCGTGCTGCCGCTGAAGGACCTGAAGGAAACCAACCGTCAGATGGCGGCCGGCGAACTG
AAGGCGCGTCAGGCGAAGCGCGAAATGACCGAGGCGAACCTGCGTCTCGTGATCTCGATCGCGAAGAAGTACACGAACCG
CGGCCTGCAGTTCCTCGACCTGATCCAGGAAGGCAACATCGGCCTGATGAAGGCGGTGGACAAGTTCGAATACCGTCGCG
GCTACAAGTTCTCGACGTATGCGACGTGGTGGATTCGTCAGGCCATCACGCGCTCGATCGCGGACCAGGCGCGCACGATC
CGTATTCCGGTTCACATGATCGAGACGATCAACAAGATGAACCGCATCTCGCGGCAGATTCTGCAGGAAACCGGTCTCGA
GCCGGATCCGGCGACGCTGGCCGAGAAGATGGAGATGCCGGAAGACAAGATCCGCAAGATCATGAAGATCGCGAAGGAGC
CGATCTCGATGGAAACGCCGATCGGCGACGACGACGATTCCCATCTCGGCGACTTCATCGAGGACACCAACACGGTCGCG
CCGGCGGATGCCGCGCTGCATGCGAGCATGCGCGACGTCGTGAAGGACGTTCTCGATTCGCTGACGCCGCGCGAGGCGAA
GGTGCTGCGGATGCGTTTCGGTATCGAAATGAGCACCGATCACACGCTCGAGGAAGTCGGCAAGCAGTTCGACGTCACGC
GTGAGCGGATCCGTCAGATCGAGGCCAAGGCACTGCGCAAGCTGCGTCACCCGAGCCGTTCCGACAAGCTGAAGTCGTTC
CTCGAAGGGAACTGA

Upstream 100 bases:

>100_bases
TCGGGCTGTAGGCAGCCGGGGCGCCAGGAGAGAGGCTCCCCAGCGTGCTATAATATAAGGTTTCCAGCGGTTTGTTTTCT
AAGCAGAGGCGAGATTCGCG

Downstream 100 bases:

>100_bases
TTTTCGGCTTCTCCCTGTCGAACGCCGCCGGCATCCGTCGGATGCCGGTGGCGTTTGTTCCCTTTGTTGTTACAATGCCG
GCCCGGCGTCTTTGCCGGTG

Product: RNA polymerase sigma factor RpoD

Products: NA

Alternate protein names: Sigma-70 [H]

Number of amino acids: Translated: 804; Mature: 803

Protein sequence:

>804_residues
MAKTTGGKKATGKGSTEPTKKVTAAKSASSARTTSSATSTPAGKKTAAGTAQAAPAPAARTRAAARPDSGPAKPAAKRAS
AKSARDAAAAADETAVRTTHAPTVQPAVVQQPRVDIAGTANSMTKKLNEVSVDDDANQSDEQPAAAAAPGKSKVRDRRAK
EKALLKEAFATSTPGTAEELEERRVKLRALIKLGKERGFLTYAEINDHLPDNFTETEALEGIIGTFNDMGVAVYEQAPDA
ETLLLNDNAPAASSDDEVEEEAEVALSTVDSEFGRTTDPVRMYMREMGTVELLTREGEIEIAKRIEDGLRHMVMAISACP
TTIADILAMAERVANDEIRVDELVDGLLDPNASDTDTDGFSAKEAEEIENEDEEVEEEEEEEEEEDDDGAAQATANAAQL
EALKRASLEKFALISEWFDKMRRAFEKEGYKSKSYLKAQETIQSELMTIRFTARTVERLCDTLRAQVDEVRQVERQILHI
VVDKCGMPRSEFIARFPGNETDLDWAEKIAAEGHSYSAILSRNIPAIREQQQRLLDLQARVVLPLKDLKETNRQMAAGEL
KARQAKREMTEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTI
RIPVHMIETINKMNRISRQILQETGLEPDPATLAEKMEMPEDKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDTNTVA
PADAALHASMRDVVKDVLDSLTPREAKVLRMRFGIEMSTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSDKLKSF
LEGN

Sequences:

>Translated_804_residues
MAKTTGGKKATGKGSTEPTKKVTAAKSASSARTTSSATSTPAGKKTAAGTAQAAPAPAARTRAAARPDSGPAKPAAKRAS
AKSARDAAAAADETAVRTTHAPTVQPAVVQQPRVDIAGTANSMTKKLNEVSVDDDANQSDEQPAAAAAPGKSKVRDRRAK
EKALLKEAFATSTPGTAEELEERRVKLRALIKLGKERGFLTYAEINDHLPDNFTETEALEGIIGTFNDMGVAVYEQAPDA
ETLLLNDNAPAASSDDEVEEEAEVALSTVDSEFGRTTDPVRMYMREMGTVELLTREGEIEIAKRIEDGLRHMVMAISACP
TTIADILAMAERVANDEIRVDELVDGLLDPNASDTDTDGFSAKEAEEIENEDEEVEEEEEEEEEEDDDGAAQATANAAQL
EALKRASLEKFALISEWFDKMRRAFEKEGYKSKSYLKAQETIQSELMTIRFTARTVERLCDTLRAQVDEVRQVERQILHI
VVDKCGMPRSEFIARFPGNETDLDWAEKIAAEGHSYSAILSRNIPAIREQQQRLLDLQARVVLPLKDLKETNRQMAAGEL
KARQAKREMTEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTI
RIPVHMIETINKMNRISRQILQETGLEPDPATLAEKMEMPEDKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDTNTVA
PADAALHASMRDVVKDVLDSLTPREAKVLRMRFGIEMSTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSDKLKSF
LEGN
>Mature_803_residues
AKTTGGKKATGKGSTEPTKKVTAAKSASSARTTSSATSTPAGKKTAAGTAQAAPAPAARTRAAARPDSGPAKPAAKRASA
KSARDAAAAADETAVRTTHAPTVQPAVVQQPRVDIAGTANSMTKKLNEVSVDDDANQSDEQPAAAAAPGKSKVRDRRAKE
KALLKEAFATSTPGTAEELEERRVKLRALIKLGKERGFLTYAEINDHLPDNFTETEALEGIIGTFNDMGVAVYEQAPDAE
TLLLNDNAPAASSDDEVEEEAEVALSTVDSEFGRTTDPVRMYMREMGTVELLTREGEIEIAKRIEDGLRHMVMAISACPT
TIADILAMAERVANDEIRVDELVDGLLDPNASDTDTDGFSAKEAEEIENEDEEVEEEEEEEEEEDDDGAAQATANAAQLE
ALKRASLEKFALISEWFDKMRRAFEKEGYKSKSYLKAQETIQSELMTIRFTARTVERLCDTLRAQVDEVRQVERQILHIV
VDKCGMPRSEFIARFPGNETDLDWAEKIAAEGHSYSAILSRNIPAIREQQQRLLDLQARVVLPLKDLKETNRQMAAGELK
ARQAKREMTEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIR
IPVHMIETINKMNRISRQILQETGLEPDPATLAEKMEMPEDKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDTNTVAP
ADAALHASMRDVVKDVLDSLTPREAKVLRMRFGIEMSTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSDKLKSFL
EGN

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium [H]

COG id: COG0568

COG function: function code K; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

Organism=Escherichia coli, GI1789448, Length=620, Percent_Identity=55.3225806451613, Blast_Score=637, Evalue=0.0,
Organism=Escherichia coli, GI1789098, Length=225, Percent_Identity=41.7777777777778, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI1789871, Length=243, Percent_Identity=26.7489711934156, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: 700 (log & stationary phase) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000943
- InterPro:   IPR009042
- InterPro:   IPR007627
- InterPro:   IPR007624
- InterPro:   IPR007630
- InterPro:   IPR007631
- InterPro:   IPR007127
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR012760
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04546 Sigma70_ner; PF03979 Sigma70_r1_1; PF00140 Sigma70_r1_2; PF04542 Sigma70_r2; PF04539 Sigma70_r3; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 88914; Mature: 88783

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00715 SIGMA70_1 ; PS00716 SIGMA70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTTGGKKATGKGSTEPTKKVTAAKSASSARTTSSATSTPAGKKTAAGTAQAAPAPAAR
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
TRAAARPDSGPAKPAAKRASAKSARDAAAAADETAVRTTHAPTVQPAVVQQPRVDIAGTA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCH
NSMTKKLNEVSVDDDANQSDEQPAAAAAPGKSKVRDRRAKEKALLKEAFATSTPGTAEEL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
EERRVKLRALIKLGKERGFLTYAEINDHLPDNFTETEALEGIIGTFNDMGVAVYEQAPDA
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCC
ETLLLNDNAPAASSDDEVEEEAEVALSTVDSEFGRTTDPVRMYMREMGTVELLTREGEIE
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCHH
IAKRIEDGLRHMVMAISACPTTIADILAMAERVANDEIRVDELVDGLLDPNASDTDTDGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCC
SAKEAEEIENEDEEVEEEEEEEEEEDDDGAAQATANAAQLEALKRASLEKFALISEWFDK
CCHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRRAFEKEGYKSKSYLKAQETIQSELMTIRFTARTVERLCDTLRAQVDEVRQVERQILHI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVDKCGMPRSEFIARFPGNETDLDWAEKIAAEGHSYSAILSRNIPAIREQQQRLLDLQAR
HHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHH
VVLPLKDLKETNRQMAAGELKARQAKREMTEANLRLVISIAKKYTNRGLQFLDLIQEGNI
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
GLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKMNRISRQI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHH
LQETGLEPDPATLAEKMEMPEDKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDTNTVA
HHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCC
PADAALHASMRDVVKDVLDSLTPREAKVLRMRFGIEMSTDHTLEEVGKQFDVTRERIRQI
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
EAKALRKLRHPSRSDKLKSFLEGN
HHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AKTTGGKKATGKGSTEPTKKVTAAKSASSARTTSSATSTPAGKKTAAGTAQAAPAPAAR
CCCCCCCCCCCCCCCCCHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
TRAAARPDSGPAKPAAKRASAKSARDAAAAADETAVRTTHAPTVQPAVVQQPRVDIAGTA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCH
NSMTKKLNEVSVDDDANQSDEQPAAAAAPGKSKVRDRRAKEKALLKEAFATSTPGTAEEL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
EERRVKLRALIKLGKERGFLTYAEINDHLPDNFTETEALEGIIGTFNDMGVAVYEQAPDA
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCC
ETLLLNDNAPAASSDDEVEEEAEVALSTVDSEFGRTTDPVRMYMREMGTVELLTREGEIE
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCHH
IAKRIEDGLRHMVMAISACPTTIADILAMAERVANDEIRVDELVDGLLDPNASDTDTDGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCC
SAKEAEEIENEDEEVEEEEEEEEEEDDDGAAQATANAAQLEALKRASLEKFALISEWFDK
CCHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRRAFEKEGYKSKSYLKAQETIQSELMTIRFTARTVERLCDTLRAQVDEVRQVERQILHI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVDKCGMPRSEFIARFPGNETDLDWAEKIAAEGHSYSAILSRNIPAIREQQQRLLDLQAR
HHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHH
VVLPLKDLKETNRQMAAGELKARQAKREMTEANLRLVISIAKKYTNRGLQFLDLIQEGNI
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
GLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKMNRISRQI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHH
LQETGLEPDPATLAEKMEMPEDKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDTNTVA
HHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCC
PADAALHASMRDVVKDVLDSLTPREAKVLRMRFGIEMSTDHTLEEVGKQFDVTRERIRQI
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
EAKALRKLRHPSRSDKLKSFLEGN
HHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA