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The map label for this gene is folE2-1 [H]

Identifier: 189352478

GI number: 189352478

Start: 528791

End: 529600

Strand: Direct

Name: folE2-1 [H]

Synonym: BMULJ_03697

Alternate gene names: 189352478

Gene position: 528791-529600 (Clockwise)

Preceding gene: 189352477

Following gene: 189352480

Centisome position: 21.38

GC content: 64.2

Gene sequence:

>810_bases
ATGAACCAGATGAATCCCGCCTTCGTGATGCCCGACGTGCAGAGCACGGTGGATACCCGTCAGATTCCGATTCAGCGCGT
GGGCGTGAAGGCGGTCCGGCATCCGTTGACGGTGCTCACCGAAAGCGGCGACGTGCAGCCGACGGTCGGCGTCTGGAATC
TCGACGTTCGTTTGCCGGCCGAGCAGAAGGGCACGCACATGTCGCGTTTCGTCGCGCTGCTCGAGGAGAACCGCGCGCCG
CTGACGATCGAGCGCTTCCGCGCGATGATCGCGTCGATGCTCGAGAAGCTCGAGGCGGAAGCCGGCCGCATCGAAGTGAC
GTTCCCGTACTTCGTCAACAAGACCGCACCGGTGTCGGGCGTGCAGAGTCTGCTGGACTACGAAGTGACGCTCGCAGGCG
AAAGCCGCAACGGCGACACGCGCCTGTTCCTCAAGGTGCTCGTTCCGGTGACGAGCCTGTGCCCGTGCTCGAAGAAGATC
TCGCAGTACGGTGCGCACAACCAGCGCTCGCACGTGACGATCGACGCCGAACTCGCGGCCGACGTGCCGGTCGAGGCGCT
GATCCGCATCGCGGAAGAAGAGGCGTCGTGCGAGCTGTGGGGGCTGCTGAAGCGCCCGGACGAGAAGTTCGTCACCGAGC
GTGCGTACGAGAATCCGAAGTTCGTCGAGGACCTCGTGCGCGACGTCGCGGCGCGTCTCGATGCGGACGCACGCATTGTC
GCGTATGTGCTCGAAGCGGAGAACTTCGAGTCGATTCACAATCACAGCGCGTATGCGCTGATCGAGCGCGACAAGCGGCA
TGCCGCGTAA

Upstream 100 bases:

>100_bases
TGCGGAAAAACATGGGCCTGCGGGCCCATGTTGCTTTTCCGGCTGCCGCATGATGCGGCGTGCGCGTCGTCGAACGCGCG
GCTTACAAGGATTGAACAAG

Downstream 100 bases:

>100_bases
CGCGCGACCGACTACGCGCCGGCTTCGGCACGGCGCGAGCGTCGAATGAAGAAAAGGCCGCAGCAGCGGCCTTTTTCATC
TGCGCGGATCGCGCGGCGCG

Product: putative GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MNQMNPAFVMPDVQSTVDTRQIPIQRVGVKAVRHPLTVLTESGDVQPTVGVWNLDVRLPAEQKGTHMSRFVALLEENRAP
LTIERFRAMIASMLEKLEAEAGRIEVTFPYFVNKTAPVSGVQSLLDYEVTLAGESRNGDTRLFLKVLVPVTSLCPCSKKI
SQYGAHNQRSHVTIDAELAADVPVEALIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVAARLDADARIV
AYVLEAENFESIHNHSAYALIERDKRHAA

Sequences:

>Translated_269_residues
MNQMNPAFVMPDVQSTVDTRQIPIQRVGVKAVRHPLTVLTESGDVQPTVGVWNLDVRLPAEQKGTHMSRFVALLEENRAP
LTIERFRAMIASMLEKLEAEAGRIEVTFPYFVNKTAPVSGVQSLLDYEVTLAGESRNGDTRLFLKVLVPVTSLCPCSKKI
SQYGAHNQRSHVTIDAELAADVPVEALIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVAARLDADARIV
AYVLEAENFESIHNHSAYALIERDKRHAA
>Mature_269_residues
MNQMNPAFVMPDVQSTVDTRQIPIQRVGVKAVRHPLTVLTESGDVQPTVGVWNLDVRLPAEQKGTHMSRFVALLEENRAP
LTIERFRAMIASMLEKLEAEAGRIEVTFPYFVNKTAPVSGVQSLLDYEVTLAGESRNGDTRLFLKVLVPVTSLCPCSKKI
SQYGAHNQRSHVTIDAELAADVPVEALIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVAARLDADARIV
AYVLEAENFESIHNHSAYALIERDKRHAA

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate [H]

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042 [H]

Pfam domain/function: PF02649 DUF198 [H]

EC number: =3.5.4.16 [H]

Molecular weight: Translated: 30106; Mature: 30106

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQMNPAFVMPDVQSTVDTRQIPIQRVGVKAVRHPLTVLTESGDVQPTVGVWNLDVRLPA
CCCCCCCEECCCHHHHHHHHCCCHHHHHHHHHHCCHHEEECCCCCCCCEEEEEEEEECCC
EQKGTHMSRFVALLEENRAPLTIERFRAMIASMLEKLEAEAGRIEVTFPYFVNKTAPVSG
HHCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCHHH
VQSLLDYEVTLAGESRNGDTRLFLKVLVPVTSLCPCSKKISQYGAHNQRSHVTIDAELAA
HHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEHHHCC
DVPVEALIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVAARLDADARIV
CCCHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEE
AYVLEAENFESIHNHSAYALIERDKRHAA
EEEECCCCHHHHHCCCEEEEEECCCCCCC
>Mature Secondary Structure
MNQMNPAFVMPDVQSTVDTRQIPIQRVGVKAVRHPLTVLTESGDVQPTVGVWNLDVRLPA
CCCCCCCEECCCHHHHHHHHCCCHHHHHHHHHHCCHHEEECCCCCCCCEEEEEEEEECCC
EQKGTHMSRFVALLEENRAPLTIERFRAMIASMLEKLEAEAGRIEVTFPYFVNKTAPVSG
HHCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCHHH
VQSLLDYEVTLAGESRNGDTRLFLKVLVPVTSLCPCSKKISQYGAHNQRSHVTIDAELAA
HHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEHHHCC
DVPVEALIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVAARLDADARIV
CCCHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEE
AYVLEAENFESIHNHSAYALIERDKRHAA
EEEECCCCHHHHHCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA