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The map label for this gene is gudP [H]

Identifier: 189352227

GI number: 189352227

Start: 266314

End: 267726

Strand: Reverse

Name: gudP [H]

Synonym: BMULJ_03445

Alternate gene names: 189352227

Gene position: 267726-266314 (Counterclockwise)

Preceding gene: 189352229

Following gene: 189352226

Centisome position: 10.83

GC content: 68.01

Gene sequence:

>1413_bases
ATGTCCGCATCCCTGCCCCGCGCTGCCGACGGCAAGCGCTATACGTACGAGTGGTACGTCGTCGTCATCTGCATGCTTGC
GTACGTCTTTTCGTTCGTCGATCGCCAAGTGCTCGTGCTGATGATCGAGCCGATCAAGCGCGATCTGCATCTGACCGATA
CGCAGTTCAGTCTGCTGAACGGCTTCGCGTTCTCGCTGTTCTACGCCGTGATGGGGCTGCCCGTCGCCTATCTCGCCGAT
CGCTATGCGCGCCCGCGCATCATCTCGCTCGGCATCGCGCTGTGGAGCATCGCGACCGCGCTGTGCGGGCTCAGCCAGCA
CTTCGTGCACATGTTCGTCGCGCGCATGGGCGTCGGCGTCGGCGAAGCCGCGCTGTCGCCCGGCGCCTATTCGATGCTCG
CCGACTACTTTCCGAAGGAGAAGCTCGGCCGCGCGATCGCCGTGTATTCGCTCGGCTCGTTCATCGGCGGCGGCGTCGCG
TTCCTGATCGGCGGCTATGTGATCGCGCTGCTCAAGCATGCGAGCGCGTTCACGCTGCCGATCGTCGGGCAGGTGCATGC
GTGGCAGGTCACGTTCCTGATCGTCGGGCTGCCCGGCCTGCTCGTCGCGCTGCTGTTCGTCGCGACCGTGCGCGACCCGC
AGCGCAAGGGGCTCGCGCAGGATCGTTCCGGCGCCGTGCGGCGCGTATCGATGCGCGATTCGCTGCGTTTCGTCGGCACG
CATCGCGCGACGTTCGCGTGCCACTATCTCGGCTTCTCGTTCTATGCGATGGCGCTGTACTGCCTGCTCAGCTGGACGCC
CGCGTTCTATATCCGCCGGTTCGGGATGACGGCCGTCGAAGCCGGCTACACGCTCGGCATCGTGTTGCTCGTCGCGAACA
CGGCCGGCGTATTCTGCGGCGGCTGGCTCAACGACTGGCTGCTGCGGCGCGGCCGCGTCGATGCGCCGATGCGCGCGGGC
GCGATCGGCGCCGCATGCATGATCCTGCCCGCCACGCTGTTCACGCAGCTCGACGCGCTGCCGGCGTCGCTCGCCATGCT
CGTGATCGCGATGTTCTTTGCGTCGTTTCCGATGCCGACGTCGACCGCCGCGATGCAAACGCTCGCACCGAACCAGATGC
GCGCGCAAATCTCCGCGCTGTTCCTGCTCGTCTCGAACCTGATCGCGCTCGGCATCGGCACGACCGTCGTCGCGCTGTTC
ACCGATCGCGTGTTCGGCACACCGGCGGCGGTCGGTCACTCGATGTCGATCGTCAACGTCGCGGCGGCCGCGCTCGCGGC
GCTGCTGCTCGGCGCCGGCTGCCGCCACTATCGCCGCAGCCTCGAGCGCGAGCGCGGCCACGTGCAGGCGGCCGCACCCG
CCGCCGATAGCGCGGCCGGCGCGATCGCCGCGTCTGGATCGGGGGCGCGCTGA

Upstream 100 bases:

>100_bases
CCCGAGCTTTTCGACCTGTTCGACTTTTTTCGCACCGCGACGGCGGCCGCCAGCGGGACCGGCGCCGCGCATTCCCCTCG
CCCGCTGCTGGAGAATCCGC

Downstream 100 bases:

>100_bases
GTCCGGTTTGCGCTTGCCAGTTATCCATCCAGTTGATTAGGGCATCGTTTTTTAATCGATTTGATTTATGCGATGCCGCT
CCCTATTCTCGATCGCATCA

Product: permease of the major facilitator superfamily

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MSASLPRAADGKRYTYEWYVVVICMLAYVFSFVDRQVLVLMIEPIKRDLHLTDTQFSLLNGFAFSLFYAVMGLPVAYLAD
RYARPRIISLGIALWSIATALCGLSQHFVHMFVARMGVGVGEAALSPGAYSMLADYFPKEKLGRAIAVYSLGSFIGGGVA
FLIGGYVIALLKHASAFTLPIVGQVHAWQVTFLIVGLPGLLVALLFVATVRDPQRKGLAQDRSGAVRRVSMRDSLRFVGT
HRATFACHYLGFSFYAMALYCLLSWTPAFYIRRFGMTAVEAGYTLGIVLLVANTAGVFCGGWLNDWLLRRGRVDAPMRAG
AIGAACMILPATLFTQLDALPASLAMLVIAMFFASFPMPTSTAAMQTLAPNQMRAQISALFLLVSNLIALGIGTTVVALF
TDRVFGTPAAVGHSMSIVNVAAAALAALLLGAGCRHYRRSLERERGHVQAAAPAADSAAGAIAASGSGAR

Sequences:

>Translated_470_residues
MSASLPRAADGKRYTYEWYVVVICMLAYVFSFVDRQVLVLMIEPIKRDLHLTDTQFSLLNGFAFSLFYAVMGLPVAYLAD
RYARPRIISLGIALWSIATALCGLSQHFVHMFVARMGVGVGEAALSPGAYSMLADYFPKEKLGRAIAVYSLGSFIGGGVA
FLIGGYVIALLKHASAFTLPIVGQVHAWQVTFLIVGLPGLLVALLFVATVRDPQRKGLAQDRSGAVRRVSMRDSLRFVGT
HRATFACHYLGFSFYAMALYCLLSWTPAFYIRRFGMTAVEAGYTLGIVLLVANTAGVFCGGWLNDWLLRRGRVDAPMRAG
AIGAACMILPATLFTQLDALPASLAMLVIAMFFASFPMPTSTAAMQTLAPNQMRAQISALFLLVSNLIALGIGTTVVALF
TDRVFGTPAAVGHSMSIVNVAAAALAALLLGAGCRHYRRSLERERGHVQAAAPAADSAAGAIAASGSGAR
>Mature_469_residues
SASLPRAADGKRYTYEWYVVVICMLAYVFSFVDRQVLVLMIEPIKRDLHLTDTQFSLLNGFAFSLFYAVMGLPVAYLADR
YARPRIISLGIALWSIATALCGLSQHFVHMFVARMGVGVGEAALSPGAYSMLADYFPKEKLGRAIAVYSLGSFIGGGVAF
LIGGYVIALLKHASAFTLPIVGQVHAWQVTFLIVGLPGLLVALLFVATVRDPQRKGLAQDRSGAVRRVSMRDSLRFVGTH
RATFACHYLGFSFYAMALYCLLSWTPAFYIRRFGMTAVEAGYTLGIVLLVANTAGVFCGGWLNDWLLRRGRVDAPMRAGA
IGAACMILPATLFTQLDALPASLAMLVIAMFFASFPMPTSTAAMQTLAPNQMRAQISALFLLVSNLIALGIGTTVVALFT
DRVFGTPAAVGHSMSIVNVAAAALAALLLGAGCRHYRRSLERERGHVQAAAPAADSAAGAIAASGSGAR

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI2367379, Length=343, Percent_Identity=26.530612244898, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789152, Length=433, Percent_Identity=22.1709006928406, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082320, Length=401, Percent_Identity=22.4438902743142, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789515, Length=325, Percent_Identity=20.9230769230769, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17557872, Length=496, Percent_Identity=22.7822580645161, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17539092, Length=478, Percent_Identity=23.0125523012552, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24654039, Length=301, Percent_Identity=21.9269102990033, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17864456, Length=301, Percent_Identity=21.9269102990033, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24654037, Length=305, Percent_Identity=22.9508196721311, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24654041, Length=305, Percent_Identity=22.9508196721311, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640209, Length=170, Percent_Identity=27.0588235294118, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24654044, Length=253, Percent_Identity=22.5296442687747, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50303; Mature: 50172

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASLPRAADGKRYTYEWYVVVICMLAYVFSFVDRQVLVLMIEPIKRDLHLTDTQFSLLN
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
GFAFSLFYAVMGLPVAYLADRYARPRIISLGIALWSIATALCGLSQHFVHMFVARMGVGV
HHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GEAALSPGAYSMLADYFPKEKLGRAIAVYSLGSFIGGGVAFLIGGYVIALLKHASAFTLP
CHHHCCCCHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEC
IVGQVHAWQVTFLIVGLPGLLVALLFVATVRDPQRKGLAQDRSGAVRRVSMRDSLRFVGT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHEEEHHHHHHHHHCC
HRATFACHYLGFSFYAMALYCLLSWTPAFYIRRFGMTAVEAGYTLGIVLLVANTAGVFCG
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHCCHHHHHHHHHHCCCCCEEC
GWLNDWLLRRGRVDAPMRAGAIGAACMILPATLFTQLDALPASLAMLVIAMFFASFPMPT
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
STAAMQTLAPNQMRAQISALFLLVSNLIALGIGTTVVALFTDRVFGTPAAVGHSMSIVNV
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHH
AAAALAALLLGAGCRHYRRSLERERGHVQAAAPAADSAAGAIAASGSGAR
HHHHHHHHHHHHCHHHHHHHHHHHHCCEEECCCCCCCCCCCEECCCCCCC
>Mature Secondary Structure 
SASLPRAADGKRYTYEWYVVVICMLAYVFSFVDRQVLVLMIEPIKRDLHLTDTQFSLLN
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH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HHHHHHHHHHHHCHHHHHHHHHHHHCCEEECCCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]