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The map label for this gene is qseC [H]

Identifier: 189352201

GI number: 189352201

Start: 239473

End: 240882

Strand: Reverse

Name: qseC [H]

Synonym: BMULJ_03419

Alternate gene names: 189352201

Gene position: 240882-239473 (Counterclockwise)

Preceding gene: 189352202

Following gene: 189352196

Centisome position: 9.74

GC content: 69.72

Gene sequence:

>1410_bases
TTGCCGCGCACTGACTGGTTCCCGAAGACGCTGTTCGGGCGCACGCTGCTGTTCATCGCGCTCGTCGTCGCGACCGGCGC
GCTCGCGCTCGCCGCGATCGCGCGCTACTACGCCGGCGTCGCGGCCGAGCGCGCCTACGATCAGCTGCTCGCCGGCGCGT
CGATCCAGGTCGCGGAGAATCTTTACGTACAGGGCGGCGTGCTCGCGCTGAATCCGCCGGTCGCCGCGCTCTCGACGCTG
TCGCGCTACGACCTCGTCTACTACAAGGTCGTCGATTCGCGCGGCGTCGTCGTGGCCGGCTACAACGATCTGGCGAGCTC
CGCGACGCTCGCGGCCGCGAAACAGGGGCCCGCGTTCGCAAACGCCGTCTATCACGGGCACCGGATCCGCACGGCCACCA
TCGCGCGCTACATGCCGGAAGAAAGTACGCCGGGCTGGGCGCTCGTGACCGTTGCGCAGACAACGAATGCACGTCAGCAG
CTGACGAACGAGATGAGCATCAAGGTGTGGACGCTGATCCTGCTGATGAGCGTGCTCGCGATCGGCGCAAGCGGGCTGGC
GATCCGGCGCGGGCTGCGCCCGCTCGCGCAGATCGGCGCGATCATCGCGGCGCGCGATCCGGCCGATTTGCGGCCGGTGG
CCGTCGATACGCCGAGCGAGATCGACGCGATCATCGGCGCGATCAACGGGCTGATGCGGCGGCTCGCCGAGCGCATCAAC
GCGATGCAGCGCTTCATCGCCGACGCCGCGCACCAGATGCGCACGCCGCTCGCGCGGCTCGATGCGCAGATCGAGCTGCT
CGACGGCGACGACGATCCTGCGCGTCATGCGGCGCGGCTCGATGCGTTGCGCGCGACCTGCGCCGATGTCGGCCGGCTCA
CCGGGCAGCTGCTCAATCACGCGATGGTGATTCATCGCACCGAGGCCGTGCCGCTGCAGCCCGTCGATCTGGTCGCGCTC
GCGAAGGACGTGCTCGGCCGCGCGATCCCGCTTGCGGGCGAGCGCGACGTCGCCGTCGCATTCGCAAGCGACGCGCCGCA
CGCCTGGATCGACGGCGATGCGATCAGCCTGCAGGAAGCGCTGTCGAACGTGCTGCACAACGCGCTGCTGCACGGCCATG
CCGACGACATCGTCGTGTCGGTCGCGACGTCGGGCCATGCCGACGATGCGGTGACGCTGACCGTCACCGACAACGGGCGC
GGCATTCCGCGCGAGCATTGGGATGCCGCATTGCAGCCGTTCGTGCGGATCGCGCCGGACGGGACGGAGCGCCGTACGGG
ATCGGGGCTCGGCCTCGCGATCGTGCAGGAAGTGATGAAGGCGCACGGCGGGCGCGTCGGGTTCGCGTTTCCGGATGCGG
GCGGGTTTGCGGTCGTGCTGACGTTTCCGAAGGCGGCGCGAACGGGCTAG

Upstream 100 bases:

>100_bases
CCGAGCGCGAACGCGGTCGAGCAGTATGTAACGCGCGTGCGCAAAAAGCTGCAAGGCAGCTCGGTCGAGATCCGCACCGC
GCGCGGGATGGGGTATCAGA

Downstream 100 bases:

>100_bases
CGTCTACGCGCGAACCGACAACCGTCGCGGTTGTGCATCGCCGGTCGATTCCGTTCGTCATACGGTCGGGCCTTGAACGC
GTTGAACAGGCGGCACGACA

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MPRTDWFPKTLFGRTLLFIALVVATGALALAAIARYYAGVAAERAYDQLLAGASIQVAENLYVQGGVLALNPPVAALSTL
SRYDLVYYKVVDSRGVVVAGYNDLASSATLAAAKQGPAFANAVYHGHRIRTATIARYMPEESTPGWALVTVAQTTNARQQ
LTNEMSIKVWTLILLMSVLAIGASGLAIRRGLRPLAQIGAIIAARDPADLRPVAVDTPSEIDAIIGAINGLMRRLAERIN
AMQRFIADAAHQMRTPLARLDAQIELLDGDDDPARHAARLDALRATCADVGRLTGQLLNHAMVIHRTEAVPLQPVDLVAL
AKDVLGRAIPLAGERDVAVAFASDAPHAWIDGDAISLQEALSNVLHNALLHGHADDIVVSVATSGHADDAVTLTVTDNGR
GIPREHWDAALQPFVRIAPDGTERRTGSGLGLAIVQEVMKAHGGRVGFAFPDAGGFAVVLTFPKAARTG

Sequences:

>Translated_469_residues
MPRTDWFPKTLFGRTLLFIALVVATGALALAAIARYYAGVAAERAYDQLLAGASIQVAENLYVQGGVLALNPPVAALSTL
SRYDLVYYKVVDSRGVVVAGYNDLASSATLAAAKQGPAFANAVYHGHRIRTATIARYMPEESTPGWALVTVAQTTNARQQ
LTNEMSIKVWTLILLMSVLAIGASGLAIRRGLRPLAQIGAIIAARDPADLRPVAVDTPSEIDAIIGAINGLMRRLAERIN
AMQRFIADAAHQMRTPLARLDAQIELLDGDDDPARHAARLDALRATCADVGRLTGQLLNHAMVIHRTEAVPLQPVDLVAL
AKDVLGRAIPLAGERDVAVAFASDAPHAWIDGDAISLQEALSNVLHNALLHGHADDIVVSVATSGHADDAVTLTVTDNGR
GIPREHWDAALQPFVRIAPDGTERRTGSGLGLAIVQEVMKAHGGRVGFAFPDAGGFAVVLTFPKAARTG
>Mature_468_residues
PRTDWFPKTLFGRTLLFIALVVATGALALAAIARYYAGVAAERAYDQLLAGASIQVAENLYVQGGVLALNPPVAALSTLS
RYDLVYYKVVDSRGVVVAGYNDLASSATLAAAKQGPAFANAVYHGHRIRTATIARYMPEESTPGWALVTVAQTTNARQQL
TNEMSIKVWTLILLMSVLAIGASGLAIRRGLRPLAQIGAIIAARDPADLRPVAVDTPSEIDAIIGAINGLMRRLAERINA
MQRFIADAAHQMRTPLARLDAQIELLDGDDDPARHAARLDALRATCADVGRLTGQLLNHAMVIHRTEAVPLQPVDLVALA
KDVLGRAIPLAGERDVAVAFASDAPHAWIDGDAISLQEALSNVLHNALLHGHADDIVVSVATSGHADDAVTLTVTDNGRG
IPREHWDAALQPFVRIAPDGTERRTGSGLGLAIVQEVMKAHGGRVGFAFPDAGGFAVVLTFPKAARTG

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=321, Percent_Identity=26.1682242990654, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790551, Length=324, Percent_Identity=27.7777777777778, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790346, Length=257, Percent_Identity=28.4046692607004, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1789403, Length=298, Percent_Identity=29.8657718120805, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789808, Length=476, Percent_Identity=22.2689075630252, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788279, Length=366, Percent_Identity=24.0437158469945, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=236, Percent_Identity=28.8135593220339, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=233, Percent_Identity=28.755364806867, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=27.0742358078603, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=28.2700421940928, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788393, Length=255, Percent_Identity=27.0588235294118, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693157, Length=207, Percent_Identity=23.6714975845411, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788549, Length=233, Percent_Identity=26.1802575107296, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081816, Length=233, Percent_Identity=30.0429184549356, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49688; Mature: 49556

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRTDWFPKTLFGRTLLFIALVVATGALALAAIARYYAGVAAERAYDQLLAGASIQVAEN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHH
LYVQGGVLALNPPVAALSTLSRYDLVYYKVVDSRGVVVAGYNDLASSATLAAAKQGPAFA
EEEECCEEEECCCHHHHHHHHHHCEEEEEEECCCCEEEECCHHHHCHHHHHHHHCCCHHH
NAVYHGHRIRTATIARYMPEESTPGWALVTVAQTTNARQQLTNEMSIKVWTLILLMSVLA
HHHHCCCEEHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGASGLAIRRGLRPLAQIGAIIAARDPADLRPVAVDTPSEIDAIIGAINGLMRRLAERIN
HCCCCHHHHHCCHHHHHHHHHEEECCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHH
AMQRFIADAAHQMRTPLARLDAQIELLDGDDDPARHAARLDALRATCADVGRLTGQLLNH
HHHHHHHHHHHHHHCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMVIHRTEAVPLQPVDLVALAKDVLGRAIPLAGERDVAVAFASDAPHAWIDGDAISLQEA
HHEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEECCCHHHHHHH
LSNVLHNALLHGHADDIVVSVATSGHADDAVTLTVTDNGRGIPREHWDAALQPFVRIAPD
HHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCEEECCC
GTERRTGSGLGLAIVQEVMKAHGGRVGFAFPDAGGFAVVLTFPKAARTG
CCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCHHCCCC
>Mature Secondary Structure 
PRTDWFPKTLFGRTLLFIALVVATGALALAAIARYYAGVAAERAYDQLLAGASIQVAEN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHH
LYVQGGVLALNPPVAALSTLSRYDLVYYKVVDSRGVVVAGYNDLASSATLAAAKQGPAFA
EEEECCEEEECCCHHHHHHHHHHCEEEEEEECCCCEEEECCHHHHCHHHHHHHHCCCHHH
NAVYHGHRIRTATIARYMPEESTPGWALVTVAQTTNARQQLTNEMSIKVWTLILLMSVLA
HHHHCCCEEHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGASGLAIRRGLRPLAQIGAIIAARDPADLRPVAVDTPSEIDAIIGAINGLMRRLAERIN
HCCCCHHHHHCCHHHHHHHHHEEECCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHH
AMQRFIADAAHQMRTPLARLDAQIELLDGDDDPARHAARLDALRATCADVGRLTGQLLNH
HHHHHHHHHHHHHHCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMVIHRTEAVPLQPVDLVALAKDVLGRAIPLAGERDVAVAFASDAPHAWIDGDAISLQEA
HHEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEECCCHHHHHHH
LSNVLHNALLHGHADDIVVSVATSGHADDAVTLTVTDNGRGIPREHWDAALQPFVRIAPD
HHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCEEECCC
GTERRTGSGLGLAIVQEVMKAHGGRVGFAFPDAGGFAVVLTFPKAARTG
CCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]