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The map label for this gene is shlB [H]

Identifier: 189352167

GI number: 189352167

Start: 197730

End: 199430

Strand: Reverse

Name: shlB [H]

Synonym: BMULJ_03385

Alternate gene names: 189352167

Gene position: 199430-197730 (Counterclockwise)

Preceding gene: 189352172

Following gene: 189352166

Centisome position: 8.06

GC content: 70.78

Gene sequence:

>1701_bases
ATGCGCAACCCGATTTATGCAGTGCGAACGCTATGCACTGTCGCCCTGCTGTTGCGCTGCGTCATCTCCGTCGCGCAGGA
CACGCGCTCCTATGCGCCGCCTACCGACACCGCCCATCGCCAGGCCGAACAGATCGATCATCTGCGCGAGCAGCTCGCGC
CGCCCATCGACGCGCTGTCCGCACGGTCGCCGCACGCGACCGACCGCTTGTCGCTGCCGGCCGAAGCCGATTGTTTTGCG
ATCCATACGATCGAATGGCGGCACGCCGAAGCGTTTCCATGGCTGCCGCGCGAAGCGGCCGTCGAGCACGCATGCATCGG
GCCGCAAGGCTTGCGGACGCTGCGCGACTGGGTCACGCGCCGGCTGATCGCACGCGGCTATATCACCTCCGTCGCCGTCA
TTCCCGAACAGGATCTGTCCGGCGGCCGGCTCGTCGTCGAGATCGTGCCCGGCCGCATCGGCGCGATCCGCGACGCGGGT
GGCCGCATCGGCTGGCCCGCGCCGCTGTTCCCGCGGCACGCGCATGGGCTCTTGAACGTGCGCGATCTCGATCAGGCGCT
CGAAAACGTGCGGCGTCTGCCGGGCCAGGCCGCGACCGCGTTCGATCTCCTACCGGGCGCGGCGCTCGGCGACACCGACA
TCGTCGTCCGTCATCCGGCGGACGCACGCCGCGTGCGCGTACTCGCGACCGCCGACAACGCCGGTCTCGATGCAACGGGA
CGCAACCAGCTCGGCGCGATCGTCGCGGTCGATTCGCCGCTCCATCTCTACGACCAGCTCGTCCTCACCTACAACACCGA
TGCCGCGCGCGGCAACAAGACGCTCGGCTCGCAAGCCAAAAGCGCCGCGTGGAACGTGCCGATCGGCTATGCGTCGGTGT
CGGTCGGCATCAGCGAATGGACGTCGCGGCGGACACTGCCCGCCACGGCCGGCGGCGAAGCCGCGCTGTCGCTCGCGCAG
CGCACGCGGCGCTACGAGGCCGCATTGCGCGTCGTGCCGTACCGGACGAGCCACGGCAAGACGACGCTGCGCTTCACGCT
GTCGCGCCGCGACGACCGGAGCCGGCTCGGTTCGACCGAACTCGACGTCAATCGGCGCGACATCGTCGGCTACGACGTCG
GCATCGCGCATCGCGAGAAGCTCGCCGACGGCGCGGTCGACGCCGGCTTCGGCATGCGCGGCAGCATCCCCGCGCTCAGC
GCGCATCCGGGACGCGTCAACGATCGGCCCGCGTGGGACGGCCGCTATCGCCTCTTCACGGCGACGCTCGCGGCCGACGC
GCGCTTTCGTGTCGGCGCGCGTCGCTTCGGCTATCGCGGCACGTTGCGCGTGCAGCACGCACCGGGCGCCGCACCGTCCA
CCGAATTTCTCCAGATCGGCGGCCGCTACACGGTGCGCGGCTTCGACGGCAATCAGACGCTCGCCGGCGCGAACGGCTGG
ATCTGGCGCAACGAACTCGCGACCGGCGCGTTCGGCGCGAACGAAATCTATGCGGCGCTCGACGCCGGCCGCGTGGCGGG
CGCCGGAGCGGCTGAAGGCGCAGGCCGCGGCGGACGCACGCTCGTCGGCACGTCGGTCGGCGTACGGGGCGGCTATCGGC
TCGTCGGCTACGACGTCGCGCTCGGCGCGCCGCTGTACAAGCCCGCCCTGCTGAACACGGCGGCGGTCGCGCTCGACGTA
TCGCTGACCGCCCGTTTCTGA

Upstream 100 bases:

>100_bases
TACAAAATTATCTCGATTTAGTCGACAAAAACGGATGCCATTCAAATTCGCTTCACGCATATAGAATCCGGTCGATTTCA
CCGTCTCAATCGATCCGGAC

Downstream 100 bases:

>100_bases
TGCGCGTGCGCGTCCGCACGCGCCGTTCGTCATGGAGGATCACGCCATGTAAATCGTTCGCCCGTCACGGCCGCGCCGCA
GCGCGGCCCGTTCCGGCGCG

Product: hemolysin activation/secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MRNPIYAVRTLCTVALLLRCVISVAQDTRSYAPPTDTAHRQAEQIDHLREQLAPPIDALSARSPHATDRLSLPAEADCFA
IHTIEWRHAEAFPWLPREAAVEHACIGPQGLRTLRDWVTRRLIARGYITSVAVIPEQDLSGGRLVVEIVPGRIGAIRDAG
GRIGWPAPLFPRHAHGLLNVRDLDQALENVRRLPGQAATAFDLLPGAALGDTDIVVRHPADARRVRVLATADNAGLDATG
RNQLGAIVAVDSPLHLYDQLVLTYNTDAARGNKTLGSQAKSAAWNVPIGYASVSVGISEWTSRRTLPATAGGEAALSLAQ
RTRRYEAALRVVPYRTSHGKTTLRFTLSRRDDRSRLGSTELDVNRRDIVGYDVGIAHREKLADGAVDAGFGMRGSIPALS
AHPGRVNDRPAWDGRYRLFTATLAADARFRVGARRFGYRGTLRVQHAPGAAPSTEFLQIGGRYTVRGFDGNQTLAGANGW
IWRNELATGAFGANEIYAALDAGRVAGAGAAEGAGRGGRTLVGTSVGVRGGYRLVGYDVALGAPLYKPALLNTAAVALDV
SLTARF

Sequences:

>Translated_566_residues
MRNPIYAVRTLCTVALLLRCVISVAQDTRSYAPPTDTAHRQAEQIDHLREQLAPPIDALSARSPHATDRLSLPAEADCFA
IHTIEWRHAEAFPWLPREAAVEHACIGPQGLRTLRDWVTRRLIARGYITSVAVIPEQDLSGGRLVVEIVPGRIGAIRDAG
GRIGWPAPLFPRHAHGLLNVRDLDQALENVRRLPGQAATAFDLLPGAALGDTDIVVRHPADARRVRVLATADNAGLDATG
RNQLGAIVAVDSPLHLYDQLVLTYNTDAARGNKTLGSQAKSAAWNVPIGYASVSVGISEWTSRRTLPATAGGEAALSLAQ
RTRRYEAALRVVPYRTSHGKTTLRFTLSRRDDRSRLGSTELDVNRRDIVGYDVGIAHREKLADGAVDAGFGMRGSIPALS
AHPGRVNDRPAWDGRYRLFTATLAADARFRVGARRFGYRGTLRVQHAPGAAPSTEFLQIGGRYTVRGFDGNQTLAGANGW
IWRNELATGAFGANEIYAALDAGRVAGAGAAEGAGRGGRTLVGTSVGVRGGYRLVGYDVALGAPLYKPALLNTAAVALDV
SLTARF
>Mature_566_residues
MRNPIYAVRTLCTVALLLRCVISVAQDTRSYAPPTDTAHRQAEQIDHLREQLAPPIDALSARSPHATDRLSLPAEADCFA
IHTIEWRHAEAFPWLPREAAVEHACIGPQGLRTLRDWVTRRLIARGYITSVAVIPEQDLSGGRLVVEIVPGRIGAIRDAG
GRIGWPAPLFPRHAHGLLNVRDLDQALENVRRLPGQAATAFDLLPGAALGDTDIVVRHPADARRVRVLATADNAGLDATG
RNQLGAIVAVDSPLHLYDQLVLTYNTDAARGNKTLGSQAKSAAWNVPIGYASVSVGISEWTSRRTLPATAGGEAALSLAQ
RTRRYEAALRVVPYRTSHGKTTLRFTLSRRDDRSRLGSTELDVNRRDIVGYDVGIAHREKLADGAVDAGFGMRGSIPALS
AHPGRVNDRPAWDGRYRLFTATLAADARFRVGARRFGYRGTLRVQHAPGAAPSTEFLQIGGRYTVRGFDGNQTLAGANGW
IWRNELATGAFGANEIYAALDAGRVAGAGAAEGAGRGGRTLVGTSVGVRGGYRLVGYDVALGAPLYKPALLNTAAVALDV
SLTARF

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 60750; Mature: 60750

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNPIYAVRTLCTVALLLRCVISVAQDTRSYAPPTDTAHRQAEQIDHLREQLAPPIDALS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHC
ARSPHATDRLSLPAEADCFAIHTIEWRHAEAFPWLPREAAVEHACIGPQGLRTLRDWVTR
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
RLIARGYITSVAVIPEQDLSGGRLVVEIVPGRIGAIRDAGGRIGWPAPLFPRHAHGLLNV
HHHHHHHHEEEEEECCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCHHCCCCCH
RDLDQALENVRRLPGQAATAFDLLPGAALGDTDIVVRHPADARRVRVLATADNAGLDATG
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCCCCCCC
RNQLGAIVAVDSPLHLYDQLVLTYNTDAARGNKTLGSQAKSAAWNVPIGYASVSVGISEW
CCCCEEEEEECCCHHHEEEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCEEEEECCHHHH
TSRRTLPATAGGEAALSLAQRTRRYEAALRVVPYRTSHGKTTLRFTLSRRDDRSRLGSTE
HCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEEECCCCHHHCCCCC
LDVNRRDIVGYDVGIAHREKLADGAVDAGFGMRGSIPALSAHPGRVNDRPAWDGRYRLFT
CCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
ATLAADARFRVGARRFGYRGTLRVQHAPGAAPSTEFLQIGGRYTVRGFDGNQTLAGANGW
EEECCCCHHHHCHHHCCCCCEEEEEECCCCCCCCHHEEECCEEEEEEECCCCEEECCCCC
IWRNELATGAFGANEIYAALDAGRVAGAGAAEGAGRGGRTLVGTSVGVRGGYRLVGYDVA
EEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEEE
LGAPLYKPALLNTAAVALDVSLTARF
ECCCCCCHHHHCCEEEEEEEEEEECC
>Mature Secondary Structure
MRNPIYAVRTLCTVALLLRCVISVAQDTRSYAPPTDTAHRQAEQIDHLREQLAPPIDALS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHC
ARSPHATDRLSLPAEADCFAIHTIEWRHAEAFPWLPREAAVEHACIGPQGLRTLRDWVTR
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
RLIARGYITSVAVIPEQDLSGGRLVVEIVPGRIGAIRDAGGRIGWPAPLFPRHAHGLLNV
HHHHHHHHEEEEEECCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCHHCCCCCH
RDLDQALENVRRLPGQAATAFDLLPGAALGDTDIVVRHPADARRVRVLATADNAGLDATG
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCCCCCCC
RNQLGAIVAVDSPLHLYDQLVLTYNTDAARGNKTLGSQAKSAAWNVPIGYASVSVGISEW
CCCCEEEEEECCCHHHEEEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCEEEEECCHHHH
TSRRTLPATAGGEAALSLAQRTRRYEAALRVVPYRTSHGKTTLRFTLSRRDDRSRLGSTE
HCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEEECCCCHHHCCCCC
LDVNRRDIVGYDVGIAHREKLADGAVDAGFGMRGSIPALSAHPGRVNDRPAWDGRYRLFT
CCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
ATLAADARFRVGARRFGYRGTLRVQHAPGAAPSTEFLQIGGRYTVRGFDGNQTLAGANGW
EEECCCCHHHHCHHHCCCCCEEEEEECCCCCCCCHHEEECCEEEEEEECCCCEEECCCCC
IWRNELATGAFGANEIYAALDAGRVAGAGAAEGAGRGGRTLVGTSVGVRGGYRLVGYDVA
EEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEEE
LGAPLYKPALLNTAAVALDVSLTARF
ECCCCCCHHHHCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]