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The map label for this gene is mntH [H]

Identifier: 189352053

GI number: 189352053

Start: 71706

End: 73043

Strand: Direct

Name: mntH [H]

Synonym: BMULJ_03270

Alternate gene names: 189352053

Gene position: 71706-73043 (Clockwise)

Preceding gene: 189352050

Following gene: 189352056

Centisome position: 2.9

GC content: 67.12

Gene sequence:

>1338_bases
ATGTCGACTGTCGGCCGTAATCCACTGACCGAGCGCACTGCGTCGGGCATCCGCGACGTGTTCGCCGGCAGGCGGCGCGG
CCCCGGCACGCTGTTCCTGTTCGCGGGCCCGGCCGTGATCGCGTCGGTCGCGTATATGGACCCCGGCAACTTCGCGACCA
ACATTCGTGCAGGCGCGCAGTTCGGCTATGCGCTGCTATGGGTCGTGCTGCTCGCGAACGTGATCGCGATGCTGTTTCAG
TCGCTGTCGGCGAAGCTCGGCATCGTGACGGGCCGCAACCTCGCGGAGCTGTGCGCCGAGCACTTCCCGCGGCCGATCGT
CTATGCGATGTGGATCGTCAGCGAACTGGCGGCGATGGCGACCGATCTCGCGGAATTCCTCGGCGGCGCGATCGCGCTGG
CGCTGCTGTTCGAGCTGCCCTTGATCGTCGGGATGTTCGTCGTCGCGATGGTCACGTACGCGATCCTGCTGTTCGACCGG
AACGGCTTTCGGCCGATGGAGATCATGGTCGGCGCGCTGGTCAGCCTGATCGGGCTCTGCTATCTCGCGGAGATGTTCAT
CGCGCCGGTGGACTGGGCGCAGGTCGCGATGCACGCGGTCGTGCCGCAGATGCCGCGCGGCGATGCGCTACTCGTGTCGG
TCGGCATCGTCGGCGCGACGGTGATGCCGCATGCGCTCTATCTGCACTCGGGGCTCACGCAGCGGCGCGTGCCGGGGCTC
GATGCGGCACAGCGCCGGCTGCTCGTGCGTTATTCGAATCTCGAGGTGATCGTCGCGCTGTCGGTGGCGGGCGCGATCAA
CATGGCGATGGTCATCATGGCGAGCGCCGCGTTTCATGCCGGATTCAGCGACGTCGCGGAAATCGAGACCGCCTATCACA
CGCTGACGCCGCTGCTCGGCACGACGGCCGCCGCATTCTTTCTCGTGTCGCTGATGAGCTCCGGCATTTCGAGCTCCGCC
GTTGGCACGCTCGCCGGACAGATGATCATGCAGGGCTTCGTCGGCTTCCGGATGCCGGTGTGGCTGCGGCGGCTCGTGAC
GATGGTGCCGGCCTTCATCGTCGTCGGCGTCGGTGTCGATGCGACGCAGGCGCTGCTGATCAGCCAGGTCGTGCTGTCGT
TCGTGCTGCCGGTGCCGATGGCGGCGCTCGTCTACTTCACCGCGCGCCGCGACATCATGGGCGAGTTCGTCACGCGTCCG
GCGATGCGCTGGACCGCAATCGCGGCCGCAGTCGTCATCGCCGTGTTGAATCTCGGCTTGGGCGTCGCGATGGTGCAAAA
CGCGACGTCGACGGACGCGGCCGCACCTGCTGCTGTGCACGGCGGCGCGTCGTCGTGA

Upstream 100 bases:

>100_bases
GTTTCCCGCGGCGGATTTTTCAAGTGCCTTGCATTTCCGGCGCATCGTCAGTGCCGTTCGCGGCCGCCGCGTGCCGCCGC
CCATTCCCGCAGGAGGGACG

Downstream 100 bases:

>100_bases
TGGCGGGATGAAGCGGAGTCGGTGCGCCGCGCACGCCGCGTGACGGCCGACGGCGGCTGCGCGCTCAGTGCACGCCGGCC
GGCGCGATCGCGCGCACGGT

Product: Nramp family metal ion transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSTVGRNPLTERTASGIRDVFAGRRRGPGTLFLFAGPAVIASVAYMDPGNFATNIRAGAQFGYALLWVVLLANVIAMLFQ
SLSAKLGIVTGRNLAELCAEHFPRPIVYAMWIVSELAAMATDLAEFLGGAIALALLFELPLIVGMFVVAMVTYAILLFDR
NGFRPMEIMVGALVSLIGLCYLAEMFIAPVDWAQVAMHAVVPQMPRGDALLVSVGIVGATVMPHALYLHSGLTQRRVPGL
DAAQRRLLVRYSNLEVIVALSVAGAINMAMVIMASAAFHAGFSDVAEIETAYHTLTPLLGTTAAAFFLVSLMSSGISSSA
VGTLAGQMIMQGFVGFRMPVWLRRLVTMVPAFIVVGVGVDATQALLISQVVLSFVLPVPMAALVYFTARRDIMGEFVTRP
AMRWTAIAAAVVIAVLNLGLGVAMVQNATSTDAAAPAAVHGGASS

Sequences:

>Translated_445_residues
MSTVGRNPLTERTASGIRDVFAGRRRGPGTLFLFAGPAVIASVAYMDPGNFATNIRAGAQFGYALLWVVLLANVIAMLFQ
SLSAKLGIVTGRNLAELCAEHFPRPIVYAMWIVSELAAMATDLAEFLGGAIALALLFELPLIVGMFVVAMVTYAILLFDR
NGFRPMEIMVGALVSLIGLCYLAEMFIAPVDWAQVAMHAVVPQMPRGDALLVSVGIVGATVMPHALYLHSGLTQRRVPGL
DAAQRRLLVRYSNLEVIVALSVAGAINMAMVIMASAAFHAGFSDVAEIETAYHTLTPLLGTTAAAFFLVSLMSSGISSSA
VGTLAGQMIMQGFVGFRMPVWLRRLVTMVPAFIVVGVGVDATQALLISQVVLSFVLPVPMAALVYFTARRDIMGEFVTRP
AMRWTAIAAAVVIAVLNLGLGVAMVQNATSTDAAAPAAVHGGASS
>Mature_444_residues
STVGRNPLTERTASGIRDVFAGRRRGPGTLFLFAGPAVIASVAYMDPGNFATNIRAGAQFGYALLWVVLLANVIAMLFQS
LSAKLGIVTGRNLAELCAEHFPRPIVYAMWIVSELAAMATDLAEFLGGAIALALLFELPLIVGMFVVAMVTYAILLFDRN
GFRPMEIMVGALVSLIGLCYLAEMFIAPVDWAQVAMHAVVPQMPRGDALLVSVGIVGATVMPHALYLHSGLTQRRVPGLD
AAQRRLLVRYSNLEVIVALSVAGAINMAMVIMASAAFHAGFSDVAEIETAYHTLTPLLGTTAAAFFLVSLMSSGISSSAV
GTLAGQMIMQGFVGFRMPVWLRRLVTMVPAFIVVGVGVDATQALLISQVVLSFVLPVPMAALVYFTARRDIMGEFVTRPA
MRWTAIAAAVVIAVLNLGLGVAMVQNATSTDAAAPAAVHGGASS

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=358, Percent_Identity=33.5195530726257, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI295293167, Length=435, Percent_Identity=29.6551724137931, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI295293178, Length=435, Percent_Identity=29.6551724137931, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI295293171, Length=435, Percent_Identity=29.6551724137931, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI295293169, Length=435, Percent_Identity=29.6551724137931, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI295293175, Length=435, Percent_Identity=29.6551724137931, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI295293173, Length=435, Percent_Identity=29.6551724137931, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI10835169, Length=435, Percent_Identity=29.6551724137931, Blast_Score=155, Evalue=9e-38,
Organism=Escherichia coli, GI1788736, Length=386, Percent_Identity=45.0777202072539, Blast_Score=341, Evalue=5e-95,
Organism=Caenorhabditis elegans, GI193210616, Length=449, Percent_Identity=30.2895322939866, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17569473, Length=378, Percent_Identity=30.4232804232804, Blast_Score=181, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI71999499, Length=431, Percent_Identity=28.538283062645, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI71993856, Length=232, Percent_Identity=36.2068965517241, Blast_Score=152, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6323062, Length=389, Percent_Identity=35.4755784061697, Blast_Score=220, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6324450, Length=434, Percent_Identity=31.1059907834101, Blast_Score=202, Evalue=8e-53,
Organism=Saccharomyces cerevisiae, GI6321841, Length=399, Percent_Identity=35.3383458646617, Blast_Score=199, Evalue=6e-52,
Organism=Drosophila melanogaster, GI24648607, Length=440, Percent_Identity=32.2727272727273, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI281362176, Length=440, Percent_Identity=32.2727272727273, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI24648609, Length=440, Percent_Identity=32.2727272727273, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI45553443, Length=411, Percent_Identity=32.8467153284672, Blast_Score=195, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 46974; Mature: 46843

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVGRNPLTERTASGIRDVFAGRRRGPGTLFLFAGPAVIASVAYMDPGNFATNIRAGAQ
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHCCCCCCHHCCHHHHH
FGYALLWVVLLANVIAMLFQSLSAKLGIVTGRNLAELCAEHFPRPIVYAMWIVSELAAMA
HHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
TDLAEFLGGAIALALLFELPLIVGMFVVAMVTYAILLFDRNGFRPMEIMVGALVSLIGLC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
YLAEMFIAPVDWAQVAMHAVVPQMPRGDALLVSVGIVGATVMPHALYLHSGLTQRRVPGL
HHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHCCCCC
DAAQRRLLVRYSNLEVIVALSVAGAINMAMVIMASAAFHAGFSDVAEIETAYHTLTPLLG
CHHHHHHHHEECCCEEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TTAAAFFLVSLMSSGISSSAVGTLAGQMIMQGFVGFRMPVWLRRLVTMVPAFIVVGVGVD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
ATQALLISQVVLSFVLPVPMAALVYFTARRDIMGEFVTRPAMRWTAIAAAVVIAVLNLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
GVAMVQNATSTDAAAPAAVHGGASS
HHHHHCCCCCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
STVGRNPLTERTASGIRDVFAGRRRGPGTLFLFAGPAVIASVAYMDPGNFATNIRAGAQ
CCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHCCCCCCHHCCHHHHH
FGYALLWVVLLANVIAMLFQSLSAKLGIVTGRNLAELCAEHFPRPIVYAMWIVSELAAMA
HHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
TDLAEFLGGAIALALLFELPLIVGMFVVAMVTYAILLFDRNGFRPMEIMVGALVSLIGLC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
YLAEMFIAPVDWAQVAMHAVVPQMPRGDALLVSVGIVGATVMPHALYLHSGLTQRRVPGL
HHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHCCCCC
DAAQRRLLVRYSNLEVIVALSVAGAINMAMVIMASAAFHAGFSDVAEIETAYHTLTPLLG
CHHHHHHHHEECCCEEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TTAAAFFLVSLMSSGISSSAVGTLAGQMIMQGFVGFRMPVWLRRLVTMVPAFIVVGVGVD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
ATQALLISQVVLSFVLPVPMAALVYFTARRDIMGEFVTRPAMRWTAIAAAVVIAVLNLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
GVAMVQNATSTDAAAPAAVHGGASS
HHHHHCCCCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA