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The map label for this gene is dapA [H]

Identifier: 189352039

GI number: 189352039

Start: 55770

End: 56648

Strand: Reverse

Name: dapA [H]

Synonym: BMULJ_03256

Alternate gene names: 189352039

Gene position: 56648-55770 (Counterclockwise)

Preceding gene: 189352040

Following gene: 189352038

Centisome position: 2.29

GC content: 64.05

Gene sequence:

>879_bases
ATGCAACTGAAAGGCATTCTGCCCGCGCTGGTCACGCCGTTCGACGCATCGGGCGCGGTCGATCACGACACGCTCGCGTC
GATCCTCGAATTTCAACTCACCGCGGGCGTCAGCGGCTTCGTCCCGCTCGGCTCGACCGGCGAATACTACGCGCTGACCA
ACGATGAGCGGCGCGCGGTAATGAAGACCGTGCGCGAAGTGGTCGGCCAGCGCGGCGAACTCGTGGTGGGCGCGAACGGG
TCGTCCACGCGCGAAGTGATCGAGCAGGTGCGGCAAGCGCGCGACGCCGGCTACACCAACATCCTGATCGCGCCGCCGTA
CTACGCGCTGCCGTCGCAGCAGGAACTGATCGGCCACTACGACGCGATTCTCGCCGCTGTGACCGACGTCAACGTGATCC
TGTACAACTATCCGGTCCGCACCAACGTCGAAGTCGGCTTCGGCGTGCTCGACGCGTTCAAGGATCATCCGCGCGTGATC
GGCATCAAGGAAAGCAGCGGCAACCTGTTGCGCGCGATCGAGATCGGCGGCAAGTACAAGGATCACTATCAGCTGTCGTG
CGGCTCGGACGATCAGGCGCTCGACTTCTTCCTGTGGGGCGCGACGAGCTGGATCTGCGGGCCCGCGAACTGCTTCGCGA
AGCAGGTCGTGAGCTTCTACGACAAATTCTCGGCCGGCGACATCGCAGGCGCGCAGAACGTGATGCGCGCGCTGTTCCCG
GTGATGGCGAGCATGGAGTCGGGCAAGTTTATCCAGAAGGTCAAGTACGGCTGCGAACTGGCGGGCTTCAAGGTCGGCAA
TGCGCGCATGCCGCTGCAGCCGCTGACCGACCAGGAGAAGGCCGAGTTCCGCGCGATCTTCGAAGCGTCGCAGGCGTAA

Upstream 100 bases:

>100_bases
CGCCTTTCCGCTGACCCGCCTGGTCGGCGTAGTGGAGTCCAGGATGCTCAGGCGCTACGCCTATTAACTCGCAACGCTCT
CAACAAGCCGGAGAAATCTC

Downstream 100 bases:

>100_bases
TCCCATGACGCGCACCGGCACCGCGTGGCGCCGGTGCGCCGACCGAGGAACCTCAACATGACGATTCACGGCTTTACCTG
TATCGAAGGCCATACCGAGG

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MQLKGILPALVTPFDASGAVDHDTLASILEFQLTAGVSGFVPLGSTGEYYALTNDERRAVMKTVREVVGQRGELVVGANG
SSTREVIEQVRQARDAGYTNILIAPPYYALPSQQELIGHYDAILAAVTDVNVILYNYPVRTNVEVGFGVLDAFKDHPRVI
GIKESSGNLLRAIEIGGKYKDHYQLSCGSDDQALDFFLWGATSWICGPANCFAKQVVSFYDKFSAGDIAGAQNVMRALFP
VMASMESGKFIQKVKYGCELAGFKVGNARMPLQPLTDQEKAEFRAIFEASQA

Sequences:

>Translated_292_residues
MQLKGILPALVTPFDASGAVDHDTLASILEFQLTAGVSGFVPLGSTGEYYALTNDERRAVMKTVREVVGQRGELVVGANG
SSTREVIEQVRQARDAGYTNILIAPPYYALPSQQELIGHYDAILAAVTDVNVILYNYPVRTNVEVGFGVLDAFKDHPRVI
GIKESSGNLLRAIEIGGKYKDHYQLSCGSDDQALDFFLWGATSWICGPANCFAKQVVSFYDKFSAGDIAGAQNVMRALFP
VMASMESGKFIQKVKYGCELAGFKVGNARMPLQPLTDQEKAEFRAIFEASQA
>Mature_292_residues
MQLKGILPALVTPFDASGAVDHDTLASILEFQLTAGVSGFVPLGSTGEYYALTNDERRAVMKTVREVVGQRGELVVGANG
SSTREVIEQVRQARDAGYTNILIAPPYYALPSQQELIGHYDAILAAVTDVNVILYNYPVRTNVEVGFGVLDAFKDHPRVI
GIKESSGNLLRAIEIGGKYKDHYQLSCGSDDQALDFFLWGATSWICGPANCFAKQVVSFYDKFSAGDIAGAQNVMRALFP
VMASMESGKFIQKVKYGCELAGFKVGNARMPLQPLTDQEKAEFRAIFEASQA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=293, Percent_Identity=27.9863481228669, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI13540533, Length=303, Percent_Identity=22.4422442244224, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1788823, Length=285, Percent_Identity=30.8771929824561, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1786463, Length=285, Percent_Identity=30.5263157894737, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI87082415, Length=276, Percent_Identity=26.0869565217391, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789620, Length=287, Percent_Identity=25.0871080139373, Blast_Score=91, Evalue=6e-20,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31749; Mature: 31749

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKGILPALVTPFDASGAVDHDTLASILEFQLTAGVSGFVPLGSTGEYYALTNDERRAV
CCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCEEEEECHHHHHH
MKTVREVVGQRGELVVGANGSSTREVIEQVRQARDAGYTNILIAPPYYALPSQQELIGHY
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHH
DAILAAVTDVNVILYNYPVRTNVEVGFGVLDAFKDHPRVIGIKESSGNLLRAIEIGGKYK
HHHHHHHHCCEEEEEECCCCCCCEECHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCC
DHYQLSCGSDDQALDFFLWGATSWICGPANCFAKQVVSFYDKFSAGDIAGAQNVMRALFP
CCEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VMASMESGKFIQKVKYGCELAGFKVGNARMPLQPLTDQEKAEFRAIFEASQA
HHHCCCCCHHHHHHHHCCEEECEEECCCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLKGILPALVTPFDASGAVDHDTLASILEFQLTAGVSGFVPLGSTGEYYALTNDERRAV
CCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCEEEEECHHHHHH
MKTVREVVGQRGELVVGANGSSTREVIEQVRQARDAGYTNILIAPPYYALPSQQELIGHY
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHH
DAILAAVTDVNVILYNYPVRTNVEVGFGVLDAFKDHPRVIGIKESSGNLLRAIEIGGKYK
HHHHHHHHCCEEEEEECCCCCCCEECHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCC
DHYQLSCGSDDQALDFFLWGATSWICGPANCFAKQVVSFYDKFSAGDIAGAQNVMRALFP
CCEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VMASMESGKFIQKVKYGCELAGFKVGNARMPLQPLTDQEKAEFRAIFEASQA
HHHCCCCCHHHHHHHHCCEEECEEECCCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA