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The map label for this gene is pcaI [H]

Identifier: 189352016

GI number: 189352016

Start: 34976

End: 35689

Strand: Direct

Name: pcaI [H]

Synonym: BMULJ_03233

Alternate gene names: 189352016

Gene position: 34976-35689 (Clockwise)

Preceding gene: 189352015

Following gene: 189352017

Centisome position: 1.41

GC content: 66.95

Gene sequence:

>714_bases
ATGGTCAACAAGATTTTCGAATCGCTTCAGTCGGCGGTCGCCGACGTTCACGACGGCGCGACGATCATGATCGGCGGCTT
CGGCACGGCCGGCATGCCGTCCGAGCTGATCGACGCGCTGATCGAGCAGGGCGCGCGCGACCTGACGATCGTCAACAACA
ACGCGGGCAACGGCGAGACGGGCCTGGCGGCCCTGCTGAAGGCGAAGCGGGTGCGCAAGATCATCTGCTCGTTCCCGCGC
CAGAGCGACTCGCAGGTGTTCGACGCGCTGTACCGCGCGGGCGAGATCGAGCTGGAGCTCGTGCCGCAGGGCAACCTGGC
CGAGCGCATTCGCGCGGCGGGTGCCGGCATCGGCGGCTTCTTCACGCCGACCGGCTATGGCACGAAGCTCGCGGAAGGCA
AGGAAACGCGCGTGATCGACGGCAAGCCGTACGTCTTCGAAACGCCGATTCACGCCGATTTCGCGCTCGTGAAGGCGTAC
AAGGGCGATCGCTGGGGCAATCTCGTCTATCGCAAGACCGCGCGCAACTTCGGGCCGATCATGGCGAGCGCCGCGAAGGT
CGCGATCGTGCAGGTGTCGCAGGTCGTGCCGCTCGGCGCGCTGAACCCGGAACACATCGTGACGCCGGGGATTTTCGTGC
AGCGCATCGTCGAAGTGCCGCAGGCCGCGCATGCGGCCGAGCTGGCCGCAGAACGCGCATCGCAAGCCGCCTGA

Upstream 100 bases:

>100_bases
CAAAACGCCGAAGCCGGAGCCGGTTTCGGCACGGCACGCGGCACGCGCGTGTTCCTCCGACAGCCGCGCATCGTGCCGCG
GGTTCGTATCAGGAAGAGAC

Downstream 100 bases:

>100_bases
CCGCCCGAGGAGATCCGACATGAAACGACTGACCCGCGATGAAATGGCCAAGCGCGTCGCCCAGGACATCCCCGAAGGCG
CGTATGTGAACCTCGGCATC

Product: 3-oxoadipate CoA-transferase alpha subunit

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MVNKIFESLQSAVADVHDGATIMIGGFGTAGMPSELIDALIEQGARDLTIVNNNAGNGETGLAALLKAKRVRKIICSFPR
QSDSQVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGFFTPTGYGTKLAEGKETRVIDGKPYVFETPIHADFALVKAY
KGDRWGNLVYRKTARNFGPIMASAAKVAIVQVSQVVPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERASQAA

Sequences:

>Translated_237_residues
MVNKIFESLQSAVADVHDGATIMIGGFGTAGMPSELIDALIEQGARDLTIVNNNAGNGETGLAALLKAKRVRKIICSFPR
QSDSQVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGFFTPTGYGTKLAEGKETRVIDGKPYVFETPIHADFALVKAY
KGDRWGNLVYRKTARNFGPIMASAAKVAIVQVSQVVPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERASQAA
>Mature_237_residues
MVNKIFESLQSAVADVHDGATIMIGGFGTAGMPSELIDALIEQGARDLTIVNNNAGNGETGLAALLKAKRVRKIICSFPR
QSDSQVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGFFTPTGYGTKLAEGKETRVIDGKPYVFETPIHADFALVKAY
KGDRWGNLVYRKTARNFGPIMASAAKVAIVQVSQVVPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERASQAA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=234, Percent_Identity=43.1623931623932, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI11545841, Length=233, Percent_Identity=44.6351931330472, Blast_Score=192, Evalue=3e-49,
Organism=Escherichia coli, GI1788551, Length=214, Percent_Identity=44.8598130841121, Blast_Score=194, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17531517, Length=237, Percent_Identity=41.7721518987342, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21358325, Length=231, Percent_Identity=46.7532467532467, Blast_Score=202, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24655794, Length=231, Percent_Identity=46.7532467532467, Blast_Score=202, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 25154; Mature: 25154

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKIFESLQSAVADVHDGATIMIGGFGTAGMPSELIDALIEQGARDLTIVNNNAGNGET
CHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHH
GLAALLKAKRVRKIICSFPRQSDSQVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGF
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCC
FTPTGYGTKLAEGKETRVIDGKPYVFETPIHADFALVKAYKGDRWGNLVYRKTARNFGPI
CCCCCCCCCCCCCCCCEEECCCCEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
MASAAKVAIVQVSQVVPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERASQAA
HHHHHHHHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVNKIFESLQSAVADVHDGATIMIGGFGTAGMPSELIDALIEQGARDLTIVNNNAGNGET
CHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHH
GLAALLKAKRVRKIICSFPRQSDSQVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGF
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCC
FTPTGYGTKLAEGKETRVIDGKPYVFETPIHADFALVKAYKGDRWGNLVYRKTARNFGPI
CCCCCCCCCCCCCCCCEEECCCCEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
MASAAKVAIVQVSQVVPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERASQAA
HHHHHHHHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]