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The map label for this gene is fnr [H]

Identifier: 189352007

GI number: 189352007

Start: 27073

End: 27819

Strand: Reverse

Name: fnr [H]

Synonym: BMULJ_03224

Alternate gene names: 189352007

Gene position: 27819-27073 (Counterclockwise)

Preceding gene: 189352008

Following gene: 189352005

Centisome position: 1.12

GC content: 65.33

Gene sequence:

>747_bases
ATGCTGACGCCCGTCGCCACACGCCCCGCCGCCACGCCGCAAGCAAACGGCTGGGCGCCTCGTCAGGCTGCGCACTGCTC
GTCGTGCGCGATGCGGCACCTTTGCATGCCGCAAGGCCTCGCCCCCGAAGCGCTGAGCCGCCTCGAAGCGGTGATCTGCG
CCGCGCGTCCCGTCAAGCGCGGTGAAGCGCTGTTCCGCGAAGGCGATGCGTTCGACAACCTGTATGCGGTCCGTTCCGGT
TCGCTGAAAACGGTTGCGACGCGTCACGACGGTCGCGAGCAGGTCACGGGTCTCCATCTCGCCGGCGAAGCGCTCGGCCT
CGACGGCATCTGCGACGACACCCACCCGCGTACCGCGATCGCGCTCGAAGACAGCTCCGTCTGCGTGATTCCGTACGCCG
CGCTGAAAGCGCTGTGCTCGGAAGCCGGCTCGATGCAACTGCGCATGCACAAGCTGATGAGCGAGCAGATCGTGCGCGAA
ACGTCGCAAGCGATGCTGCTCGGTTCGCTGAACGCCGAAGAGCGTGTCGCCGCGTTCCTGCTCGACGTATCGTCGCGCTA
TCTGAAGCGCGGTTACTCGCCGTCGGAATTCAATCTGCGGATGACGCGCGAAGACATCGGCAGCTATCTCGGCATGACGC
TCGAAACGGTCAGCCGCACGCTCTCGAAATTCCAGAAGCGCGGCCTCATCGAAATGCGCGGCCGCCTCGTTCAGATCGTC
GACTTCGACGGCCTGCATCACGTGTGA

Upstream 100 bases:

>100_bases
GCTTGCACGCGCGGGCGCGCCGTCGCGACGTTTTGTCACCCGACACGCGCATCTTGCGGTGGGACAATGATTCCGTCGAT
TCAACGCCGGAGTAAACATC

Downstream 100 bases:

>100_bases
TCGTGCGACGCGCGGCGCCTGTACTGCGCGCCGCCTTAGCGCCCCTCTCCCGCCTTCCCCGCCGCATCGTCAATCGAGAA
ACAGCGCGGCGCGCGCCTTC

Product: CRP/FNR family anaerobic regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MLTPVATRPAATPQANGWAPRQAAHCSSCAMRHLCMPQGLAPEALSRLEAVICAARPVKRGEALFREGDAFDNLYAVRSG
SLKTVATRHDGREQVTGLHLAGEALGLDGICDDTHPRTAIALEDSSVCVIPYAALKALCSEAGSMQLRMHKLMSEQIVRE
TSQAMLLGSLNAEERVAAFLLDVSSRYLKRGYSPSEFNLRMTREDIGSYLGMTLETVSRTLSKFQKRGLIEMRGRLVQIV
DFDGLHHV

Sequences:

>Translated_248_residues
MLTPVATRPAATPQANGWAPRQAAHCSSCAMRHLCMPQGLAPEALSRLEAVICAARPVKRGEALFREGDAFDNLYAVRSG
SLKTVATRHDGREQVTGLHLAGEALGLDGICDDTHPRTAIALEDSSVCVIPYAALKALCSEAGSMQLRMHKLMSEQIVRE
TSQAMLLGSLNAEERVAAFLLDVSSRYLKRGYSPSEFNLRMTREDIGSYLGMTLETVSRTLSKFQKRGLIEMRGRLVQIV
DFDGLHHV
>Mature_248_residues
MLTPVATRPAATPQANGWAPRQAAHCSSCAMRHLCMPQGLAPEALSRLEAVICAARPVKRGEALFREGDAFDNLYAVRSG
SLKTVATRHDGREQVTGLHLAGEALGLDGICDDTHPRTAIALEDSSVCVIPYAALKALCSEAGSMQLRMHKLMSEQIVRE
TSQAMLLGSLNAEERVAAFLLDVSSRYLKRGYSPSEFNLRMTREDIGSYLGMTLETVSRTLSKFQKRGLIEMRGRLVQIV
DFDGLHHV

Specific function: Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metab

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=223, Percent_Identity=43.0493273542601, Blast_Score=207, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27125; Mature: 27125

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPVATRPAATPQANGWAPRQAAHCSSCAMRHLCMPQGLAPEALSRLEAVICAARPVKR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHH
GEALFREGDAFDNLYAVRSGSLKTVATRHDGREQVTGLHLAGEALGLDGICDDTHPRTAI
HHHHHHCCCCHHHHHEECCCCEEEEEECCCCHHHHHHHEECCHHHCCCCCCCCCCCCEEE
ALEDSSVCVIPYAALKALCSEAGSMQLRMHKLMSEQIVRETSQAMLLGSLNAEERVAAFL
EECCCCEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LDVSSRYLKRGYSPSEFNLRMTREDIGSYLGMTLETVSRTLSKFQKRGLIEMRGRLVQIV
HHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEE
DFDGLHHV
ECCCCCCC
>Mature Secondary Structure
MLTPVATRPAATPQANGWAPRQAAHCSSCAMRHLCMPQGLAPEALSRLEAVICAARPVKR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHH
GEALFREGDAFDNLYAVRSGSLKTVATRHDGREQVTGLHLAGEALGLDGICDDTHPRTAI
HHHHHHCCCCHHHHHEECCCCEEEEEECCCCHHHHHHHEECCHHHCCCCCCCCCCCCEEE
ALEDSSVCVIPYAALKALCSEAGSMQLRMHKLMSEQIVRETSQAMLLGSLNAEERVAAFL
EECCCCEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LDVSSRYLKRGYSPSEFNLRMTREDIGSYLGMTLETVSRTLSKFQKRGLIEMRGRLVQIV
HHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEE
DFDGLHHV
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA